AR119202A1 - Hidroxiisoxazolinas y derivados de las mismas - Google Patents

Hidroxiisoxazolinas y derivados de las mismas

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Publication number
AR119202A1
AR119202A1 ARP200101740A ARP200101740A AR119202A1 AR 119202 A1 AR119202 A1 AR 119202A1 AR P200101740 A ARP200101740 A AR P200101740A AR P200101740 A ARP200101740 A AR P200101740A AR 119202 A1 AR119202 A1 AR 119202A1
Authority
AR
Argentina
Prior art keywords
alkyl
halo
oxazol
dihydro
trifluoromethyl
Prior art date
Application number
ARP200101740A
Other languages
English (en)
Inventor
Anne Rebstock
- Desbordes Philippe Sophie
Jeremy Dufour
Pierre Coqueron
- Genix Pierre Yves
Vincent Thomas
Sophie Ducerf
Aurelie Mallinger
Jacopo Negroni
Grtz Andreas Dr
Braun Christoph Andreas Dr
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of AR119202A1 publication Critical patent/AR119202A1/es

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/72—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
    • A01N43/80—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms five-membered rings with one nitrogen atom and either one oxygen atom or one sulfur atom in positions 1,2

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

Reivindicación 1: Un compuesto que posee la fórmula (1) siendo que R¹ se selecciona a partir del conjunto que consiste en hidrógeno, C₁₋₈-alquilo, C₃₋₈-cicloalquilo, C₂₋₈-alquenilo, C₂₋₈-alquinilo, -C₁₋₈-alquil-arilo, -C₁₋₈-alquil-C₁₋₈-alcoxi, -Si(C₁₋₈-alquil)₃, -Si-aril(C₁₋₈-alquil)₂, -C₁₋₈-alquilC₃₋₈-cicloalquilo, arilo, heteroarilo, -C₁₋₈-alquil-heteroarilo, di-C₁₋₈-alquil-fosfato, -C(=O)Rᵃ, -C(=O)N(Rᵃ)₂, -C₁₋₆-alquil-OC(=O)Rᵃ y -C₁₋₆-alquilC(=O)Rᵃ, siendo que Rᵃ se selecciona a partir del conjunto que consiste en hidrógeno, amino, C₁₋₁₀-alquilo, C₁₋₆-haloalquilo, C₂₋₈-alquenilo, C₂₋₈-haloalquenilo, C₂₋₈-alquinilo, C₂₋₈-haloalquinilo, C₁₋₈-alcoxi, C₁₋₈-haloalcoxi, C₁₋₈-alquilsulfanilo, C₁₋₈-alquilamino, di-C₁₋₈-alquilamino, -C₁₋₆-alquil-C₁₋₆-alcoxi, C₃₋₁₀-carbociclilo, C₃₋₁₀-halocarbociclilo, heterociclilo de 3 a 10 miembros, arilo, heteroarilo, heterocicliloxi, ariloxi y heteroariloxi, siendo que los radicales R¹ o Rᵃ acíclicos pueden estar sustituidos con uno o más sustituyentes R¹ᵃ y siendo que los radicales R¹ o Rᵃ cíclicos pueden estar sustituidos con uno o más sustituyentes R¹ᶜ; X es un átomo de hidrógeno, flúor o cloro; m es 0, 1 ó 2; Het es un heteroarilo de 6 miembros; n es 0, 1, 2, 3 ó 4; R² es un sustituyente que considerado en forma independiente se selecciona a partir del conjunto que consiste en halógeno, ciano, hidroxi, sulfanilo, sulfinilo, sulfonilo, amino, nitro, C₁₋₆-alquilo, C₁₋₆-haloalquilo, C₁₋₆-hidroxialquilo, C₁₋₆-cianoalquilo, C₁₋₆-alcoxi, C₁₋₆-haloalcoxi, C₁₋₆-alquilamino, di-C₁₋₆-alquilamino, C₂₋₆-alquenilo, C₂₋₆-haloalquenilo, C₂₋₆-hidroxialquenilo, C₂₋₆-cianoalquenilo, C₂₋₆-alquinilo, C₂₋₆-haloalquinilo, C₂₋₆-hidroxialquilino, C₂₋₆-cianoalquinilo, C₁₋₆-alquilsulfanilo, pentafluoro-l⁶-sulfanilo, arilsulfanilo, C₁₋₆-alquilsulfinilo, arilsulfinilo, C₁₋₆-alquilsulfonilo, arilsulfonilo, C₃₋₁₀-carbociclilo, heterociclilo de 3 a 10 miembros, arilo, heteroarilo, C₃₋₁₀-carbocicliloxi, heterocicliloxi de 3 a 10 miembros, ariloxi, heteroariloxi, -Si(C₁₋₆-alquil)₃, -C(=O)R²¹, -C(=O)OR²¹, -C(=O)N(R²¹)₂, -C(=O)N(OR²¹)R²¹, -C(=O)NR²¹N(R²¹)₂, -C(=S)N(R²¹)₂, -C(=NR²¹)R²¹, -C(=NR²¹)N(R²¹)₂, -C(=NOR²¹)R²¹, -N(R²¹)₂, -NR²¹C(=O)OR²¹, -N(OR²¹)C(=O)OR²¹, -NR²¹C(=O)N(R²¹)₂, -NR²¹C(=O)R²¹, -N(OR²¹)C(=O)R²¹, -NR²¹C(=S)R²¹, -NR²¹C(=S)N(R²¹)₂, -NR²¹C(=NR²¹)R²¹, -OC(=O)R²¹, -OC(=O)N(R²¹)₂, -NR²¹S(=O)₂R²¹, -N=CR²¹-N(R²¹)₂, -S(=O)₂R²¹, -S(=O)₂N(R²¹)₂, -P(=O)(OR²¹)₂, -O-C₁₋₆-(halo)alquil-arilo, -C₁₋₆-(halo)alquil-C₃₋₁₀-carbociclilo, -C₁₋₆-(halo)alquil-O-C₃₋₁₀-carbociclilo, -C₁₋₆-(halo)alquil-heterociclilo de 3 a 10 miembros, -C₁₋₆-(halo)alquil-O-heterociclilo de 3 a 10 miembros, -C₁₋₆-(halo)alquil-arilo, -C₁₋₆-(halo)alquil-heteroarilo, -C₁₋₆-(halo)alquil-heteroariloxi, -C₁₋₆-(halo)alquil-OR²¹, -C₁₋₆-(halo)alquil-C(=O)R²¹, -C₁₋₆-(halo)alquil-C(=O)OR²¹, -C₁₋₆-(halo)alquil-C(=O)N(R²¹)₂, -C₁₋₆-(halo)alquil-C(=O)N(OR²¹)R²¹, -C₁₋₆-(halo)alquil-C(=O)NR²¹N(R²¹)₂, -C₁₋₆-(halo)alquil-C(=S)N(R²¹)₂, -C₁₋₆-(halo)alquil-C(=NR²¹)R²¹, -C₁₋₆-(halo)alquil-C(=NR²¹)N(R²¹)₂, -C₁₋₆-(halo)alquil-C(=NOH)R²¹, -C₁₋₆-(halo)alquil-N(R²¹)₂, -C₁₋₆-(halo)alquil-NR²¹C(=O)OR²¹, -C₁₋₆-(halo)alquil-N(OR²¹)C(=O)OR²¹, -C₁₋₆-(halo)alquil-NR²¹C(=O)N(R²¹)₂, -C₁₋₆-(halo)alquil-NR²¹C(=O)R²¹, -C₁₋₆-(halo)alquil-N(OR²¹)C(=O)R²¹, -C₁₋₆-(halo)alquil-NR²¹C(=S)R²¹, -C₁₋₆-(halo)alquil-NR²¹C(=S)N(R²¹)₂, -C₁₋₆-(halo)alquil-NR²¹C(=NR²¹)R²¹, -C₁₋₆-(halo)alquil-OC(=O)R²¹, -C₁₋₆-(halo)alquil-OC(=O)N(R²¹)₂, -C₁₋₆-(halo)alquilNR²¹S(=O)₂R²¹, -C₁₋₆-(halo)alquil-N=CR²¹-N(R²¹)₂, -C₁₋₆-(halo)alquil-SR²¹, -C₁₋₆-(halo)alquil-S(=O)R²¹, -C₁₋₆-(halo)alquil-S(=O)OR²¹, -C₁₋₆-(halo)alquil-S(=O)₂R²¹, -C₁₋₆-(halo)alquil-S(=O)₂OR²¹, -C₁₋₆-(halo)alquil-S(=O)₂N(R²¹)₂ y -C₁₋₆-(halo)alquil-P(=O)(OR²¹)₂, siendo que R²¹ se selecciona en forma independiente a partir del conjunto que consiste en hidrógeno, C₁₋₆-(halo)alquilo, C₃₋₁₀-carbociclilo, heterociclilo de 3 a 10 miembros, arilo, heteroarilo y -C₁₋₆-(halo)alquil-arilo, siendo que los radicales R² y R²¹ acíclicos pueden estar sustituidos con uno o más sustituyentes R²²ᵃ y los radicales R² y R²¹ cíclicos pueden estar sustituidos con uno o más sustituyentes R²²ᶜ; R¹ᵃ, R²²ᵃ, R¹ᶜ y R²²ᶜ considerados en forma independiente se seleccionan a partir del conjunto que consiste en átomo de halógeno, nitro, hidroxilo, ciano, carboxilo, amino, sulfanilo, pentafluoro-l⁶-sulfanilo, formilo, carbamoilo, carbamato, C₁₋₆-alquilo, C₃₋₇-cicloalquilo, C₁₋₆-haloalquilo, C₃₋₈-halocicloalquilo, C₂₋₆-(halo)alquenilo, C₂₋₆-(halo)alquinilo, C₁₋₆-alquilamino, di-C₁₋₆-alquilamino, -Si(C₁₋₆-alquil)₃, C₁₋₆-(halo)alcoxiC₁₋₆-(halo)alquilsulfanilo, C₁₋₆-(halo)alquilcarbonilo, C₁₋₆-alquilcarbamoilo, di-C₁₋₆-alquilcarbamoilo, C₁₋₆-(halo)alcoxicarbonilo, ariloxi, C₁₋₆-(halo)alquilcarboniloxi, C₁₋₆-(halo)alquilcarbonilamino, C₁₋₈-(halo)alquilsulfanilo, C₁₋₈-(halo)alquilsulfinilo, C₁₋₈-(halo)alquilsulfonilo, C₁₋₈-alquilsulfonilamino, C₁₋₈-haloalquilsulfonilamino, sulfamoilo, C₁₋₈-alquilsulfamoilo y di-C₁₋₈-alquilsulfamoilo; o una sal, N-óxido o solvato de [la estructura representada por dicha fórmula], siendo que el compuesto conforme a la fórmula (1) no es: 3-[4-(2-metoxipiridin-3-il)fenil)-5-(trifluorometil)-4,5-dihidro-1,2-oxazol-5-ol, 3-[4-(piridin-3-il)fenil)-5-(trifluorometil)-4,5-dihidro-1,2-oxazol-5-ol, 3-[4-(pirimidin-5-il)fenil)-5-(trifluorometil)-4,5-dihidro-1,2-oxazol-5-ol, 3-[4-(6-fluoropiridin-3-il)fenil)-5-(trifluorometil)-4,5-dihidro-1,2-oxazol-5-ol, N-(4-{4-[5-hidroxi-5-(trifluorometil)-4,5-dihidro-1,2-oxazol-3-il)fenil}piridin-2-il)acetamida, N-(5-{4-[5-hidroxi-5-(trifluorometil)-4,5-dihidro-1,2-oxazol-3-il)fenil}piridin-2-il)acetamida, 3-[4-(6-metoxipiridin-3-il)fenil)-5-(trifluorometil)-4,5-dihidro-1,2-oxazol-5-ol, 3-[4-(2-fluoropiridin-4-il)fenil)-5-(trifluorometil)-4,5-dihidro-1,2-oxazol-5-ol, 3-[4-(piridin-4-il)fenil)-5-(trifluorometil)-4,5-dihidro-1,2-oxazol-5-ol, 3-[4-(3-fluoropiridin-4-il)fenil)-5-(trifluorometil)-4,5-dihidro-1,2-oxazol-5-ol, 3-[4-(4-metoxipiridin-3-il)fenil)-5-(trifluorometil)-4,5-dihidro-1,2-oxazol-5-ol, 3-[4-(2-fluoropiridin-3-il)fenil)-5-(trifluorometil)-4,5-dihidro-1,2-oxazol-5-ol, ni 3-[4-(3-metoxipiridin-4-il)fenil)-5-(trifluorometil)-4,5-dihidro-1,2-oxazol-5-ol.
ARP200101740A 2019-06-21 2020-06-19 Hidroxiisoxazolinas y derivados de las mismas AR119202A1 (es)

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EP (1) EP3986891A1 (es)
AR (1) AR119202A1 (es)
BR (1) BR112021025242A2 (es)
TW (1) TW202116761A (es)
UY (1) UY38758A (es)
WO (1) WO2020254486A1 (es)

Family Cites Families (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3639877A1 (de) 1986-11-21 1988-05-26 Bayer Ag Hetarylalkyl substituierte 5- und 6-ringheterocyclen
SK283036B6 (sk) 1997-05-09 2003-02-04 Agraquest, Inc. Biologicky čistá kultúra kmeňa Bacillus subtilis, metabolit, supernatant, prostriedok a spôsob ochrany alebo ošetrenia rastlín a plodov
AU8977398A (en) 1997-07-23 1999-02-16 Basf Aktiengesellschaft Substituted 3-phenyl isoxazolines
US6245551B1 (en) 1999-03-30 2001-06-12 Agraquest, Inc. Strain of Bacillus pumilus for controlling plant diseases caused by fungi
JP4071036B2 (ja) 2001-11-26 2008-04-02 クミアイ化学工業株式会社 バシルスｓｐ．Ｄ７４７菌株およびそれを用いた植物病害防除剤および害虫防除剤
GB0213715D0 (en) 2002-06-14 2002-07-24 Syngenta Ltd Chemical compounds
TWI312272B (en) 2003-05-12 2009-07-21 Sumitomo Chemical Co Pyrimidine compound and pests controlling composition containing the same
GB0414438D0 (en) 2004-06-28 2004-07-28 Syngenta Participations Ag Chemical compounds
RU2392273C2 (ru) 2004-09-10 2010-06-20 Синджента Лимитед Замещенные изоксазолы в качестве фунгицидов
KR101310073B1 (ko) 2004-10-20 2013-09-24 이하라케미칼 고교가부시키가이샤 3-트리아졸릴페닐설파이드 유도체 및 그것을유효성분으로서 함유하는 살충·살진드기·살선충제
BRPI0616839A2 (pt) 2005-10-06 2013-01-01 Nippon Soda Co agentes para controle de praga, e, compostos de amina cìclicos
EP1878730A1 (en) 2006-07-12 2008-01-16 Bayer Schering Pharma Aktiengesellschaft Substituted isoxazolines, pharmaceutical compositions containing the same, methods of preparing the same, and uses of the same
WO2009051956A2 (en) 2007-10-16 2009-04-23 E. I. Du Pont De Nemours And Company Pyrazole-substituted isoxazoline insecticides
JP5268461B2 (ja) 2008-07-14 2013-08-21 Ｍｅｉｊｉ Ｓｅｉｋａファルマ株式会社 Ｐｆ１３６４物質、その製造方法、生産菌株、及び、それを有効成分とする農園芸用殺虫剤
CN101337940B (zh) 2008-08-12 2012-05-02 国家农药创制工程技术研究中心 具杀虫活性的含氮杂环二氯烯丙醚类化合物
CN101337937B (zh) 2008-08-12 2010-12-22 国家农药创制工程技术研究中心 具有杀虫活性的n-苯基-5-取代氨基吡唑类化合物
CN101715774A (zh) 2008-10-09 2010-06-02 浙江化工科技集团有限公司 一个具有杀虫活性化合物制备及用途
EP2184273A1 (de) 2008-11-05 2010-05-12 Bayer CropScience AG Halogen-substituierte Verbindungen als Pestizide
GB0820344D0 (en) 2008-11-06 2008-12-17 Syngenta Ltd Herbicidal compositions
CA2746394C (en) 2008-12-12 2017-08-29 Syngenta Limited Spiroheterocyclic n-oxypiperidines as pesticides
WO2011085575A1 (zh) 2010-01-15 2011-07-21 江苏省农药研究所股份有限公司 邻杂环甲酰苯胺类化合物及其合成方法和应用
AR081721A1 (es) 2010-02-25 2012-10-17 Nippon Soda Co Compuesto de amina ciclica y acaricida
CN103002741A (zh) 2010-05-31 2013-03-27 先正达参股股份有限公司 作物增强的方法
EP2628389A4 (en) 2010-08-31 2014-01-01 Meiji Seika Pharma Co Ltd AGENT FOR COMBATING HARMFUL ORGANISMS
CN101967139B (zh) 2010-09-14 2013-06-05 中化蓝天集团有限公司 一种含一氟甲氧基吡唑的邻甲酰氨基苯甲酰胺类化合物、其合成方法及应用
WO2013050317A1 (en) 2011-10-03 2013-04-11 Syngenta Limited Polymorphs of an isoxazoline derivative
CN102391261A (zh) 2011-10-14 2012-03-28 上海交通大学 一种n-取代噁二嗪类化合物及其制备方法和应用
TWI566701B (zh) 2012-02-01 2017-01-21 日本農藥股份有限公司 芳烷氧基嘧啶衍生物及包含該衍生物作為有效成分的農園藝用殺蟲劑及其使用方法
ES2626360T3 (es) 2012-03-30 2017-07-24 Basf Se Compuestos de piridinilideno tiocarbonilo N-sustituidos y su uso para combatir plagas de animales
EP2647626A1 (en) 2012-04-03 2013-10-09 Syngenta Participations AG. 1-Aza-spiro[4.5]dec-3-ene and 1,8-diaza-spiro[4.5]dec-3-ene derivatives as pesticides
MA37572B1 (fr) 2012-04-27 2017-10-31 Dow Agrosciences Llc Compositions pesticides et procédés correspondants
US9282739B2 (en) 2012-04-27 2016-03-15 Dow Agrosciences Llc Pesticidal compositions and processes related thereto
CN103232431B (zh) 2013-01-25 2014-11-05 青岛科技大学 一种二卤代吡唑酰胺类化合物及其应用
CN103109816B (zh) 2013-01-25 2014-09-10 青岛科技大学 硫代苯甲酰胺类化合物及其应用
WO2014158644A1 (en) 2013-03-13 2014-10-02 Dow Agrosciences Llc Process for the preparation of triaryl rhamnose carbamates
EP2999333B1 (en) 2013-05-23 2018-06-13 Syngenta Participations AG Tank-mix formulations
CN103265527B (zh) 2013-06-07 2014-08-13 江苏省农用激素工程技术研究中心有限公司 邻氨基苯甲酰胺化合物及其制备方法和应用
CN103524422B (zh) 2013-10-11 2015-05-27 中国农业科学院植物保护研究所 苯并咪唑衍生物及其制备方法和用途
CN105636440A (zh) 2013-10-17 2016-06-01 美国陶氏益农公司 制备杀虫化合物的方法
CN105636441B (zh) 2013-10-17 2018-06-15 美国陶氏益农公司 制备杀虫化合物的方法
JP2017078022A (ja) 2014-02-28 2017-04-27 クミアイ化学工業株式会社 イソキサゾール誘導体及びそれを用いた農園芸用植物病害防除剤
WO2016005276A1 (en) 2014-07-07 2016-01-14 Bayer Cropscience Aktiengesellschaft Process for preparing fluorinated iminopyridine compounds
PE20171735A1 (es) 2015-02-17 2017-12-04 Nippon Soda Co Composicion agroquimica
CN107995925B (zh) 2015-03-26 2022-04-29 拜耳作物科学有限合伙公司 新型类芽孢杆菌属菌株、抗真菌化合物以及它们的使用方法
CN110621669A (zh) 2017-05-04 2019-12-27 巴斯夫欧洲公司 防除植物病原性真菌的取代5-卤代烷基-5-羟基异噁唑类
WO2019034602A1 (de) 2017-08-17 2019-02-21 Bayer Aktiengesellschaft Herbizid wirksame 3-phenyl-5-trifluormethylisoxazolin-5-carboxamide von cyclopentylcarbonsäuren und -estern
BR112020012518A2 (pt) 2017-12-22 2020-11-24 Bayer Aktiengesellschaft hidroxi-isoxazolinas e derivados das mesmas

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EP3986891A1 (en) 2022-04-27

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