AR099553A1 - Construcciones de proteína uspa2 y usos de las mismas - Google Patents
Construcciones de proteína uspa2 y usos de las mismasInfo
- Publication number
- AR099553A1 AR099553A1 ARP150100500A ARP150100500A AR099553A1 AR 099553 A1 AR099553 A1 AR 099553A1 AR P150100500 A ARP150100500 A AR P150100500A AR P150100500 A ARP150100500 A AR P150100500A AR 099553 A1 AR099553 A1 AR 099553A1
- Authority
- AR
- Argentina
- Prior art keywords
- uspa2
- compositions
- same
- immunogenic compositions
- immunogenic
- Prior art date
Links
- 102000004169 proteins and genes Human genes 0.000 title abstract 3
- 108090000623 proteins and genes Proteins 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 abstract 6
- 230000002163 immunogen Effects 0.000 abstract 5
- 241000588655 Moraxella catarrhalis Species 0.000 abstract 3
- 239000000427 antigen Substances 0.000 abstract 2
- 102000036639 antigens Human genes 0.000 abstract 2
- 108091007433 antigens Proteins 0.000 abstract 2
- 230000001225 therapeutic effect Effects 0.000 abstract 2
- 229960005486 vaccine Drugs 0.000 abstract 2
- 241000606768 Haemophilus influenzae Species 0.000 abstract 1
- 102000018697 Membrane Proteins Human genes 0.000 abstract 1
- 108010052285 Membrane Proteins Proteins 0.000 abstract 1
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 1
- 239000012634 fragment Substances 0.000 abstract 1
- 229940047650 haemophilus influenzae Drugs 0.000 abstract 1
- HNDVDQJCIGZPNO-UHFFFAOYSA-N histidine Natural products OC(=O)C(N)CC1=CN=CN1 HNDVDQJCIGZPNO-UHFFFAOYSA-N 0.000 abstract 1
- 125000000487 histidyl group Chemical group [H]N([H])C(C(=O)O*)C([H])([H])C1=C([H])N([H])C([H])=N1 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/21—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pseudomonadaceae (F)
- C07K14/212—Moraxellaceae, e.g. Acinetobacter, Moraxella, Oligella, Psychrobacter
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
- C07K16/1203—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
- C07K16/1217—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria from Neisseriaceae (F)
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Mycology (AREA)
- Gastroenterology & Hepatology (AREA)
- Veterinary Medicine (AREA)
- Microbiology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
Abstract
La presente solicitud se refiere a composiciones que comprenden la proteína superficial ubicua A2 (UspA2) de Moraxella catarrhalis (M. catarrhalis). De una manera más particular, la presente solicitud se refiere a construcciones de proteína UspA2 y a composiciones inmunogénicas que comprenden las construcciones, a vacunas que comprenden estas composiciones inmunogénicas, y a los usos terapéuticos de las mismas. La solicitud se refiere además a composiciones que comprenden UspA2 en combinación con cuando menos un antígeno a partir de Haemophilus influenzae, a composiciones inmunogénicas que comprenden los antígenos, a vacunas que comprenden estas composiciones inmunogénicas, y a los usos terapéuticos de las mismas. Reivindicación 1: Una proteína de la fórmula (1): A-(R¹)ₘ-(B)ₙ (1) en donde: A es UspA2 a partir de Moraxella catarrhalis o un fragmento inmunogénico de la misma; R¹ es un aminoácido; m es 0 ó 2; B es histidina; y n es 0, 1, 2, 3, 4, 5 ó 6.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461943909P | 2014-02-24 | 2014-02-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR099553A1 true AR099553A1 (es) | 2016-08-03 |
Family
ID=53476606
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP150100500A AR099553A1 (es) | 2014-02-24 | 2015-02-20 | Construcciones de proteína uspa2 y usos de las mismas |
Country Status (1)
| Country | Link |
|---|---|
| AR (1) | AR099553A1 (es) |
-
2015
- 2015-02-20 AR ARP150100500A patent/AR099553A1/es active IP Right Grant
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| UY36006A (es) | Construcciones de proteína uspa2 y usos de las mismas. | |
| CO2018004321A2 (es) | Anticuerpo que neutraliza el virus respiratorio sincitial humano | |
| CY1122824T1 (el) | Πρωτεϊνες συντηξης και εμβολια συνδυασμου | |
| BR112017008165A2 (pt) | anticorpos de domínio único direcionados contra antígenos intracelulares | |
| BR112018011073A2 (pt) | anticorpos antimiostatina, polipeptídeos contendo regiões fc variantes e métodos de utilização | |
| EA201790294A1 (ru) | Средства на основе флагеллина и применения, включающие эффективную вакцинацию | |
| CY1120740T1 (el) | Βελτιωμενα ευλογοϊικα εμβολια | |
| MX2015013065A (es) | Proteinas f de rsv de prefusion y su uso. | |
| EP4272750A3 (en) | Protein antigens that provide protection against pneumococcal colonization and/or disease | |
| EA201790507A1 (ru) | Способы и композиции для усиления иммунных ответов | |
| MY189495A (en) | Hand, foot, and mouth vaccines and methods of manufacture and use thereof | |
| DK3146042T3 (da) | Rekombinant klassisk svinepestvirus (CSFV) med substitution i E2-proteinets TAV-epitop | |
| EA201790558A1 (ru) | Композиция с пониженной иммуногенностью | |
| EA201690115A1 (ru) | Комбинированные иммуногенные композиции | |
| MX363149B (es) | Vacunas de nucleoproteina de la influenza. | |
| BR112014020025A8 (pt) | Vacinas de subunidade de rotavirus e métodos de produção e uso das mesmas | |
| MX2019007924A (es) | Vacunas contra la influenza. | |
| EA201990768A1 (ru) | Оптимизированные синтетические консенсусные иммуногенные композиции, нацеленные на белок активации фибробластов | |
| EA201390735A1 (ru) | Композиции вакцин с фрагментами расщепленных иммуноглобулинов | |
| AR099553A1 (es) | Construcciones de proteína uspa2 y usos de las mismas | |
| WO2018066948A3 (ko) | 다수의 에피토프로 구성된 재조합 항원 단백질 및 이의 제조방법 | |
| WO2015070207A3 (en) | Ama-1 epitopes, antibodies, compositions, and methods of making and using the same | |
| PL406631A1 (pl) | Antygen, szczepionka przeciwko grypie, układ do wytwarzania szczepionki, sposób wytwarzania antygenu oraz zastosowanie antygenu określonego powyżej do wytwarzania szczepionki przeciwko grypie | |
| MX2015013808A (es) | Vacuna contra garrapatas rhipicephalus. | |
| ECSP18039827A (es) | Anticuerpo que neutraliza el virus respiratorio sincitial humano |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant, registration |