AR098588A1 - Composiciones para el cuidado oral - Google Patents
Composiciones para el cuidado oralInfo
- Publication number
- AR098588A1 AR098588A1 ARP140104484A ARP140104484A AR098588A1 AR 098588 A1 AR098588 A1 AR 098588A1 AR P140104484 A ARP140104484 A AR P140104484A AR P140104484 A ARP140104484 A AR P140104484A AR 098588 A1 AR098588 A1 AR 098588A1
- Authority
- AR
- Argentina
- Prior art keywords
- amount
- phosphate
- calcium
- effective amount
- orally acceptable
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 13
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 abstract 10
- 239000000551 dentifrice Substances 0.000 abstract 5
- 239000000377 silicon dioxide Substances 0.000 abstract 5
- 229910019142 PO4 Inorganic materials 0.000 abstract 4
- XPPKVPWEQAFLFU-UHFFFAOYSA-J diphosphate(4-) Chemical class [O-]P([O-])(=O)OP([O-])([O-])=O XPPKVPWEQAFLFU-UHFFFAOYSA-J 0.000 abstract 4
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 abstract 4
- 239000010452 phosphate Substances 0.000 abstract 4
- 239000004475 Arginine Substances 0.000 abstract 3
- KRHYYFGTRYWZRS-UHFFFAOYSA-M Fluoride anion Chemical compound [F-] KRHYYFGTRYWZRS-UHFFFAOYSA-M 0.000 abstract 3
- ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 abstract 3
- 235000009697 arginine Nutrition 0.000 abstract 3
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 abstract 2
- GWEVSGVZZGPLCZ-UHFFFAOYSA-N Titan oxide Chemical compound O=[Ti]=O GWEVSGVZZGPLCZ-UHFFFAOYSA-N 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- PUZPDOWCWNUUKD-UHFFFAOYSA-M sodium fluoride Chemical group [F-].[Na+] PUZPDOWCWNUUKD-UHFFFAOYSA-M 0.000 abstract 2
- 239000001488 sodium phosphate Substances 0.000 abstract 2
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 abstract 1
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 abstract 1
- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 abstract 1
- 229930064664 L-arginine Natural products 0.000 abstract 1
- 235000014852 L-arginine Nutrition 0.000 abstract 1
- 125000002059 L-arginyl group Chemical group O=C([*])[C@](N([H])[H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H] 0.000 abstract 1
- 239000002202 Polyethylene glycol Substances 0.000 abstract 1
- DBMJMQXJHONAFJ-UHFFFAOYSA-M Sodium laurylsulphate Chemical compound [Na+].CCCCCCCCCCCCOS([O-])(=O)=O DBMJMQXJHONAFJ-UHFFFAOYSA-M 0.000 abstract 1
- 239000011230 binding agent Substances 0.000 abstract 1
- 239000011575 calcium Substances 0.000 abstract 1
- 229910052791 calcium Inorganic materials 0.000 abstract 1
- JUNWLZAGQLJVLR-UHFFFAOYSA-J calcium diphosphate Chemical class [Ca+2].[Ca+2].[O-]P([O-])(=O)OP([O-])([O-])=O JUNWLZAGQLJVLR-UHFFFAOYSA-J 0.000 abstract 1
- 239000001506 calcium phosphate Substances 0.000 abstract 1
- 229910000389 calcium phosphate Inorganic materials 0.000 abstract 1
- 235000011010 calcium phosphates Nutrition 0.000 abstract 1
- BNIILDVGGAEEIG-UHFFFAOYSA-L disodium hydrogen phosphate Chemical compound [Na+].[Na+].OP([O-])([O-])=O BNIILDVGGAEEIG-UHFFFAOYSA-L 0.000 abstract 1
- 229910000397 disodium phosphate Inorganic materials 0.000 abstract 1
- 235000019800 disodium phosphate Nutrition 0.000 abstract 1
- 235000003599 food sweetener Nutrition 0.000 abstract 1
- -1 for example Substances 0.000 abstract 1
- 235000011187 glycerol Nutrition 0.000 abstract 1
- 239000003906 humectant Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 229910000403 monosodium phosphate Inorganic materials 0.000 abstract 1
- 235000019799 monosodium phosphate Nutrition 0.000 abstract 1
- 239000000049 pigment Substances 0.000 abstract 1
- 229920001223 polyethylene glycol Polymers 0.000 abstract 1
- AJPJDKMHJJGVTQ-UHFFFAOYSA-M sodium dihydrogen phosphate Chemical compound [Na+].OP(O)([O-])=O AJPJDKMHJJGVTQ-UHFFFAOYSA-M 0.000 abstract 1
- FQENQNTWSFEDLI-UHFFFAOYSA-J sodium diphosphate Chemical compound [Na+].[Na+].[Na+].[Na+].[O-]P([O-])(=O)OP([O-])([O-])=O FQENQNTWSFEDLI-UHFFFAOYSA-J 0.000 abstract 1
- 235000013024 sodium fluoride Nutrition 0.000 abstract 1
- 239000011775 sodium fluoride Substances 0.000 abstract 1
- 235000019333 sodium laurylsulphate Nutrition 0.000 abstract 1
- 239000000600 sorbitol Substances 0.000 abstract 1
- 239000003765 sweetening agent Substances 0.000 abstract 1
- 235000019818 tetrasodium diphosphate Nutrition 0.000 abstract 1
- 239000002562 thickening agent Substances 0.000 abstract 1
- 239000004408 titanium dioxide Substances 0.000 abstract 1
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
- A61K8/86—Polyethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/20—Halogens; Compounds thereof
- A61K8/21—Fluorides; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/24—Phosphorous; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/25—Silicon; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/29—Titanium; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/46—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur
- A61K8/463—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur containing sulfuric acid derivatives, e.g. sodium lauryl sulfate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
- A61K2800/28—Rubbing or scrubbing compositions; Peeling or abrasive compositions; Containing exfoliants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/42—Colour properties
- A61K2800/43—Pigments; Dyes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/48—Thickener, Thickening system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Inorganic Chemistry (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Cosmetics (AREA)
Abstract
Composiciones dentífricas que comprenden arginina junto con sales de fluoruro, fosfato y pirofosfato, en una base de dentífrico con abrasivo de sílice libre de calcio, cuyas composiciones proporcionan remineralización, junto con métodos de uso y de fabricación de estas composiciones. Reivindicación 1: Una composición de dentífrico, caracterizada porque comprende una cantidad efectiva de arginina, en forma libre o de sal oralmente aceptable; una cantidad efectiva de fuente de iones de fluoruro; una cantidad efectiva de una mezcla de sales de fosfato y pirofosfato oralmente aceptables; en una base de dentífrico con un abrasivo de sílice libre de calcio. Reivindicación 3: La composición de conformidad con cualquier reivindicación precedente, caracterizada porque la composición comprende menos de 2% de calcio. Reivindicación 4: La composición de conformidad con cualquier reivindicación precedente, caracterizada porque la mezcla de sales de fosfato y pirofosfato oralmente aceptables no comprende sales de fosfato de calcio o pirofosfato de calcio. Reivindicación 13: La composición de conformidad con cualquier reivindicación precedente, caracterizada porque la cantidad efectiva de arginina en forma de sal libre u oralmente aceptable es L-arginina, presente en una cantidad de 4 - 8%; la cantidad efectiva de fuente de iones de fluoruro es fluoruro de sodio presente en una cantidad de 0.1 - 0.5%; la cantidad efectiva de una mezcla de sales de fosfato y pirofosfato oralmente aceptables comprende: fosfato disódico en una cantidad de 3 - 4%, fosfato monosódico en una cantidad de 0.1 - 0.5%; y pirofosfato tetrasódico en una cantidad de 0.1 - 1%; y la base del dentífrico con abrasivo de sílice comprende: humectante, por ejemplo seleccionado de sorbitol, glicerina y mezclas de los mismos en una cantidad de 40 - 60%; espesante de sílice en una cantidad de 5 - 15%; abrasivo de sílice en una cantidad de 5 - 25%; polietilenglicol en una cantidad de 1 - 5%; aglutinante en una cantidad de 0.5 - 2%; lauril sulfato de sodio en una cantidad de 1 - 2%; saborizante y edulcorante en una cantidad de 1 - 3%; pigmento, por ejemplo, dióxido de titanio: 0.5 - 2%; y agua.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US2013/072755 WO2015084321A1 (en) | 2013-12-03 | 2013-12-03 | Oral care compositions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR098588A1 true AR098588A1 (es) | 2016-06-01 |
Family
ID=50023837
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP140104484A AR098588A1 (es) | 2013-12-03 | 2014-12-02 | Composiciones para el cuidado oral |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US10543163B2 (es) |
| EP (1) | EP3076920B1 (es) |
| CN (1) | CN105792800B (es) |
| AR (1) | AR098588A1 (es) |
| AU (1) | AU2013406790B2 (es) |
| BR (1) | BR112016012151B1 (es) |
| CA (1) | CA2927611C (es) |
| IL (1) | IL245700A0 (es) |
| MX (1) | MX363315B (es) |
| PH (1) | PH12016500875B1 (es) |
| RU (1) | RU2683030C1 (es) |
| TW (2) | TWI712427B (es) |
| WO (1) | WO2015084321A1 (es) |
| ZA (1) | ZA201602211B (es) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3095048C (en) * | 2018-03-29 | 2023-07-11 | The Procter & Gamble Company | Oral care compositions comprising a stannous ion source and a neutral amino acid for promoting gum health |
| CN111936115A (zh) * | 2018-03-29 | 2020-11-13 | 宝洁公司 | 用于促进牙龈健康的口腔护理组合物 |
| EP3773452A1 (en) * | 2018-03-29 | 2021-02-17 | The Procter & Gamble Company | Oral care compositions for promoting gum health |
| CA3155870C (en) | 2019-09-30 | 2024-04-16 | The Procter & Gamble Company | Dentifrice compositions for treatment of dental biofilm |
| WO2021062607A1 (en) | 2019-09-30 | 2021-04-08 | The Procter & Gamble Company | Oral care compositions comprising hops beta acid and amino acid |
| EP4037637A1 (en) | 2019-09-30 | 2022-08-10 | The Procter & Gamble Company | Dentifrice compositions for treatment of dental biofilm |
| EP4037777A1 (en) | 2019-09-30 | 2022-08-10 | The Procter & Gamble Company | Methods of use of oral care compositions comprising hops |
| WO2021195110A1 (en) * | 2020-03-24 | 2021-09-30 | Colgate-Palmolive Company | Improved methods for manufacturing arginine dentifrice |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3943241A (en) | 1971-08-30 | 1976-03-09 | General Mills, Inc. | Cariostatic composition |
| GB1408922A (en) | 1972-02-02 | 1975-10-08 | Blendax Werke Schneider Co | Process and composition for the remineralisation and prevention of demineralisation of human teeth |
| US4064138A (en) | 1975-11-12 | 1977-12-20 | General Mills, Inc. | Amino acid derivatives |
| US4340583A (en) * | 1979-05-23 | 1982-07-20 | J. M. Huber Corporation | High fluoride compatibility dentifrice abrasives and compositions |
| US4528181A (en) | 1984-02-01 | 1985-07-09 | Colgate-Palmolive Company | Dentifrice containing dual sources of fluoride |
| EP0634924A4 (en) | 1992-04-07 | 1996-07-31 | Smithkline Beecham Corp | DENTAL FORMULATIONS. |
| WO1997002802A1 (en) * | 1995-07-10 | 1997-01-30 | Unilever N.V. | Self-heating dentifrice |
| US6436370B1 (en) | 1999-06-23 | 2002-08-20 | The Research Foundation Of State University Of New York | Dental anti-hypersensitivity composition and method |
| US9139731B2 (en) | 1999-11-12 | 2015-09-22 | The Procter & Gamble Company | Compositions and methods for improving overall tooth health and appearance |
| ITMI20070555A1 (it) | 2007-03-21 | 2007-06-20 | Giuliani Spa | Composizione provvista di attivita' di inibizione sulla 5 alfa-reduttasi |
| CN103083208A (zh) | 2007-10-01 | 2013-05-08 | 高露洁-棕榄公司 | 含有植物提取物的口腔组合物 |
| CN101938982B (zh) | 2008-02-08 | 2014-06-04 | 高露洁-棕榄公司 | 口腔护理产品和其使用和制备方法 |
| PL2249784T3 (pl) | 2008-02-08 | 2016-12-30 | Produkt do higieny jamy ustnej i sposoby jego stosowania i wytwarzania | |
| EP2249786B1 (en) | 2008-02-08 | 2017-07-19 | Colgate-Palmolive Company | Oral care product and methods of use and manufacture thereof |
| TWI552762B (zh) | 2008-02-08 | 2016-10-11 | 美國棕欖公司 | 雙組分口腔保健產品 |
| EP2349189B1 (en) | 2008-11-14 | 2015-08-05 | Swissdent Cosmetics AG | Biomimetic oral care composition |
| EP2349489B1 (en) * | 2008-11-25 | 2015-11-11 | The Procter and Gamble Company | Low ph oral care compositions with fused silica and a fluoride source |
| AU2010354716B2 (en) * | 2010-06-01 | 2013-10-10 | Colgate-Palmolive Company | Oral care compositions resistant to microbial growth |
| ES2529216T3 (es) | 2010-06-23 | 2015-02-18 | Colgate-Palmolive Company | Composición oral terapéutica |
| RU2552348C2 (ru) | 2010-10-27 | 2015-06-10 | Колгейт-Палмолив Компани | Композиция для ухода за полостью рта, содержащая аргинин и карбонат кальция |
| CA2855732C (en) | 2011-12-15 | 2016-06-28 | Colgate-Palmolive Company | Aqueous oral care compositions |
-
2013
- 2013-12-03 AU AU2013406790A patent/AU2013406790B2/en active Active
- 2013-12-03 CA CA2927611A patent/CA2927611C/en active Active
- 2013-12-03 WO PCT/US2013/072755 patent/WO2015084321A1/en active Application Filing
- 2013-12-03 RU RU2016121900A patent/RU2683030C1/ru active
- 2013-12-03 MX MX2016006826A patent/MX363315B/es unknown
- 2013-12-03 CN CN201380081339.2A patent/CN105792800B/zh active Active
- 2013-12-03 EP EP13824546.9A patent/EP3076920B1/en active Active
- 2013-12-03 US US15/101,449 patent/US10543163B2/en active Active
- 2013-12-03 BR BR112016012151-1A patent/BR112016012151B1/pt active IP Right Grant
-
2014
- 2014-12-01 TW TW108112862A patent/TWI712427B/zh not_active IP Right Cessation
- 2014-12-01 TW TW103141554A patent/TWI668012B/zh not_active IP Right Cessation
- 2014-12-02 AR ARP140104484A patent/AR098588A1/es unknown
-
2016
- 2016-04-04 ZA ZA2016/02211A patent/ZA201602211B/en unknown
- 2016-05-11 PH PH12016500875A patent/PH12016500875B1/en unknown
- 2016-05-18 IL IL245700A patent/IL245700A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL245700A0 (en) | 2016-07-31 |
| EP3076920A1 (en) | 2016-10-12 |
| ZA201602211B (en) | 2019-09-25 |
| EP3076920B1 (en) | 2019-04-17 |
| PH12016500875A1 (en) | 2016-06-20 |
| TW201932096A (zh) | 2019-08-16 |
| TW201538172A (zh) | 2015-10-16 |
| WO2015084321A1 (en) | 2015-06-11 |
| RU2683030C1 (ru) | 2019-03-26 |
| TWI668012B (zh) | 2019-08-11 |
| AU2013406790B2 (en) | 2017-09-28 |
| CA2927611C (en) | 2020-11-17 |
| CN105792800A (zh) | 2016-07-20 |
| BR112016012151B1 (pt) | 2020-03-10 |
| MX2016006826A (es) | 2016-08-19 |
| AU2013406790A1 (en) | 2016-05-26 |
| CA2927611A1 (en) | 2015-06-11 |
| PH12016500875B1 (en) | 2016-06-20 |
| MX363315B (es) | 2019-03-20 |
| TWI712427B (zh) | 2020-12-11 |
| US20170020801A1 (en) | 2017-01-26 |
| CN105792800B (zh) | 2019-09-20 |
| US10543163B2 (en) | 2020-01-28 |
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