AR098337A1 - Triazolopirazina - Google Patents
TriazolopirazinaInfo
- Publication number
- AR098337A1 AR098337A1 ARP140104188A ARP140104188A AR098337A1 AR 098337 A1 AR098337 A1 AR 098337A1 AR P140104188 A ARP140104188 A AR P140104188A AR P140104188 A ARP140104188 A AR P140104188A AR 098337 A1 AR098337 A1 AR 098337A1
- Authority
- AR
- Argentina
- Prior art keywords
- 3alkyl
- optionally
- 3haloalkyl
- halogen
- groups independently
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP13192002 | 2013-11-07 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR098337A1 true AR098337A1 (es) | 2016-05-26 |
Family
ID=49518874
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP140104188A AR098337A1 (es) | 2013-11-07 | 2014-11-06 | Triazolopirazina |
Country Status (7)
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9266891B2 (en) | 2012-11-16 | 2016-02-23 | Boehringer Ingelheim International Gmbh | Substituted [1,2,4]triazolo[4,3-A]pyrazines that are BRD4 inhibitors |
| GB201311891D0 (en) | 2013-07-03 | 2013-08-14 | Glaxosmithkline Ip Dev Ltd | Novel compound |
| GB201311888D0 (en) | 2013-07-03 | 2013-08-14 | Glaxosmithkline Ip Dev Ltd | Novel compounds |
| JP7269731B2 (ja) | 2015-03-18 | 2023-05-09 | アルビナス・オペレーションズ・インコーポレイテッド | 標的タンパク質の分解向上のための化合物および方法 |
| AU2016301195B2 (en) | 2015-08-06 | 2022-09-01 | Dana-Farber Cancer Institute, Inc. | Targeted protein degradation to attenuate adoptive T-cell therapy associated adverse inflammatory responses |
| WO2017030814A1 (en) | 2015-08-19 | 2017-02-23 | Arvinas, Inc. | Compounds and methods for the targeted degradation of bromodomain-containing proteins |
| EP3436006A1 (en) | 2016-03-30 | 2019-02-06 | Wisconsin Alumni Research Foundation | Methods and compositions for modulating frataxin expression |
| WO2017197055A1 (en) | 2016-05-10 | 2017-11-16 | C4 Therapeutics, Inc. | Heterocyclic degronimers for target protein degradation |
| CN109562113A (zh) | 2016-05-10 | 2019-04-02 | C4医药公司 | 用于靶蛋白降解的螺环降解决定子体 |
| EP3455218A4 (en) | 2016-05-10 | 2019-12-18 | C4 Therapeutics, Inc. | C3 CARBON-BASED GLUTARIMIDE DEGRONIMERS FOR TARGET PROTEIN REDUCTION |
| US11311609B2 (en) | 2017-02-08 | 2022-04-26 | Dana-Farber Cancer Institute, Inc. | Regulating chimeric antigen receptors |
| US11759533B2 (en) | 2017-03-29 | 2023-09-19 | Wisconsin Alumni Research Foundation | Methods and compositions for modulating gene expression |
| EP3743067A1 (en) * | 2018-01-25 | 2020-12-02 | Boehringer Ingelheim International GmbH | Combination treatment of acute myeloid leukemia |
| US11220515B2 (en) | 2018-01-26 | 2022-01-11 | Yale University | Imide-based modulators of proteolysis and associated methods of use |
| CA3095912A1 (en) | 2018-04-13 | 2019-10-17 | Arvinas Operations, Inc. | Cereblon ligands and bifunctional compounds comprising the same |
| WO2020132561A1 (en) | 2018-12-20 | 2020-06-25 | C4 Therapeutics, Inc. | Targeted protein degradation |
| BR112022012110A2 (pt) | 2019-12-19 | 2022-12-13 | Arvinas Operations Inc | Compostos e métodos para a degradação direcionada de receptor androgênico |
| WO2021175432A1 (en) | 2020-03-04 | 2021-09-10 | Boehringer Ingelheim International Gmbh | Method for administration of an anti cancer agent |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6451796B1 (en) | 1997-11-11 | 2002-09-17 | Ono Pharmaceutical Co., Ltd. | Fused pyrazine compounds |
| EP1598353A1 (en) * | 2004-05-17 | 2005-11-23 | Boehringer Ingelheim International GmbH | Pyrrolobenzimidazolones and their use as antiproliferative agents |
| GB0919423D0 (en) | 2009-11-05 | 2009-12-23 | Glaxosmithkline Llc | Novel compounds |
| DK2496580T3 (da) | 2009-11-05 | 2014-02-24 | Glaxosmithkline Llc | Benzodiazepinbromdomænehæmmer |
| US9328117B2 (en) | 2011-06-17 | 2016-05-03 | Constellation Pharmaceuticals, Inc. | Bromodomain inhibitors and uses thereof |
| US9266891B2 (en) | 2012-11-16 | 2016-02-23 | Boehringer Ingelheim International Gmbh | Substituted [1,2,4]triazolo[4,3-A]pyrazines that are BRD4 inhibitors |
-
2014
- 2014-11-04 US US14/532,405 patent/US9428513B2/en active Active
- 2014-11-06 AR ARP140104188A patent/AR098337A1/es unknown
- 2014-11-06 TW TW103138596A patent/TW201609731A/zh unknown
- 2014-11-07 UY UY0001035827A patent/UY35827A/es unknown
- 2014-11-07 JP JP2016528151A patent/JP6370376B2/ja active Active
- 2014-11-07 WO PCT/EP2014/074069 patent/WO2015067770A1/en active Application Filing
- 2014-11-07 EP EP14793870.8A patent/EP3066104B1/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| WO2015067770A1 (en) | 2015-05-14 |
| EP3066104B1 (en) | 2017-12-06 |
| JP6370376B2 (ja) | 2018-08-08 |
| EP3066104A1 (en) | 2016-09-14 |
| TW201609731A (zh) | 2016-03-16 |
| US9428513B2 (en) | 2016-08-30 |
| JP2016540742A (ja) | 2016-12-28 |
| US20150133447A1 (en) | 2015-05-14 |
| UY35827A (es) | 2015-05-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |