AR093156A1 - Composiciones mucoadhesivas con acido hialuronico y chitosan para aplicacion topica - Google Patents

Composiciones mucoadhesivas con acido hialuronico y chitosan para aplicacion topica

Info

Publication number
AR093156A1
AR093156A1 ARP130103905A ARP130103905A AR093156A1 AR 093156 A1 AR093156 A1 AR 093156A1 AR P130103905 A ARP130103905 A AR P130103905A AR P130103905 A ARP130103905 A AR P130103905A AR 093156 A1 AR093156 A1 AR 093156A1
Authority
AR
Argentina
Prior art keywords
chitosan
treatment
salts
topical application
composition
Prior art date
Application number
ARP130103905A
Other languages
English (en)
Inventor
Bianchera Annalisa
Coruzzi Massimo
Bettini Ruggero
Elviri Lisa
Original Assignee
Mdt Intl S A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mdt Intl S A filed Critical Mdt Intl S A
Publication of AR093156A1 publication Critical patent/AR093156A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0023—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0052—Mixtures of macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0061—Use of materials characterised by their function or physical properties
    • A61L26/008—Hydrogels or hydrocolloids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/23—Carbohydrates
    • A61L2300/236—Glycosaminoglycans, e.g. heparin, hyaluronic acid, chondroitin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Materials Engineering (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Preparation (AREA)

Abstract

Composiciones acuosas de ácido hialurónico combinado con chitosán, sus sales y glicerofosfato que tienen propiedades termogelificantes y mucoadhesivas. Estas propiedades permiten su uso para el tratamiento de lesiones de la mucosa mediante administración tópica y, particularmente, para el tratamiento de la mucosa de cavidades corporales, con especial interés en lesiones derivadas de quimioterapia y/o radioterapia para el tratamiento del cáncer. Reivindicación 1: Una composición de ácido hialurónico y sus sales mezclado con chitosán y sus sales y una sal de glicerofosfato en una solución acuosa, caracterizada porque dicha composición tiene una propiedad de transición sol-gel a 35 - 38ºC que a dichas temperaturas forma un hidrogel.
ARP130103905A 2012-10-25 2013-10-25 Composiciones mucoadhesivas con acido hialuronico y chitosan para aplicacion topica AR093156A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/EP2012/071138 WO2014063735A1 (en) 2012-10-25 2012-10-25 Mucoadhesive compositions comprising hyaluronic acid and chitosan for topical application

Publications (1)

Publication Number Publication Date
AR093156A1 true AR093156A1 (es) 2015-05-20

Family

ID=47227767

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP130103905A AR093156A1 (es) 2012-10-25 2013-10-25 Composiciones mucoadhesivas con acido hialuronico y chitosan para aplicacion topica

Country Status (6)

Country Link
EP (1) EP2922581B1 (es)
AR (1) AR093156A1 (es)
ES (1) ES2627868T3 (es)
PL (1) PL2922581T3 (es)
TW (1) TWI639434B (es)
WO (1) WO2014063735A1 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11623008B2 (en) 2014-08-20 2023-04-11 Professional Compounding Centers Of America Excipient compositions for mucoadhesive pharmaceutical compositions including a synergistic combination of amylopectin, pullulan, hyaluronic acid, and xyloglucan
WO2016135219A1 (en) * 2015-02-26 2016-09-01 Fundació Institut D'investigació En Ciències De La Salut Germans Trias I Pujol Topical composition for the treatment of mucosal lesions
CN105903059A (zh) * 2016-06-21 2016-08-31 林春梅 一种抑菌医用功能敷料
CN106474050B (zh) * 2016-11-09 2019-10-29 中国药科大学 一种载有核酸适配体-阿霉素结合物的温敏原位凝胶瘤内注射制剂及其制备方法
CN107099042A (zh) * 2017-04-17 2017-08-29 大连理工大学 一种温敏型可注射水凝胶的制备方法
CN110536679B (zh) * 2017-04-20 2023-03-31 硕腾服务有限责任公司 用于治疗乳腺炎的兽医用组合物和相关方法
MX2017017192A (es) * 2017-12-20 2019-06-21 Gerardo Leyva Gomez Biopolimero de quitosano y poloxamero 407 obtenido por irradiacion gamma que exhibe propiedades fisicoqumicas y biologicas para la reparacion de heridas.

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1212892B (it) 1983-10-11 1989-11-30 Della Valle Francesco Acido ialuronico ottenuto per mezzodi filtrazione molecolare sprovvisto di attivita' infiammatoria e sua utilizzazione terapeutica
IT1273742B (it) 1994-08-01 1997-07-09 Lifegroup Spa Composizioni ad elevata bioadesivita' e mucoadesivita' utili per il trattamento di epitali e mucose
CA2212300A1 (en) 1997-08-04 1999-02-04 Abdellatif Chenite In vitro or in vivo gelfying chitosan and therapeutic uses thereof
US7767656B2 (en) * 2005-04-25 2010-08-03 Molly S Shoichet Blends of temperature sensitive and anionic polymers for drug delivery
FR2919185B1 (fr) 2007-07-23 2010-09-10 Ard Sa Utilisation d'acide hyaluronique pour la preparation de compositions destinees a l'amelioration notamment de l'etat des muqueuses

Also Published As

Publication number Publication date
WO2014063735A1 (en) 2014-05-01
ES2627868T3 (es) 2017-07-31
TW201429478A (zh) 2014-08-01
TWI639434B (zh) 2018-11-01
EP2922581B1 (en) 2017-03-15
PL2922581T3 (pl) 2017-09-29
EP2922581A1 (en) 2015-09-30

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