AR092217A1 - LIFTS OF LIFTS MODIFIED TO PRODUCE ETHANOL FROM ACETATE - Google Patents

LIFTS OF LIFTS MODIFIED TO PRODUCE ETHANOL FROM ACETATE

Info

Publication number
AR092217A1
AR092217A1 ARP130102995A ARP130102995A AR092217A1 AR 092217 A1 AR092217 A1 AR 092217A1 AR P130102995 A ARP130102995 A AR P130102995A AR P130102995 A ARP130102995 A AR P130102995A AR 092217 A1 AR092217 A1 AR 092217A1
Authority
AR
Argentina
Prior art keywords
lifts
acetate
modified
encodes
produce ethanol
Prior art date
Application number
ARP130102995A
Other languages
Spanish (es)
Inventor
Klaassen Paul
Petronella Kolen Catharina
Jeroen Adriaan Van Maris Antonius
Thomas Pronk Jacobus
Original Assignee
Dsm Ip Assets Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dsm Ip Assets Bv filed Critical Dsm Ip Assets Bv
Publication of AR092217A1 publication Critical patent/AR092217A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0008—Oxidoreductases (1.) acting on the aldehyde or oxo group of donors (1.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/06—Ethanol, i.e. non-beverage
    • C12P7/08—Ethanol, i.e. non-beverage produced as by-product or from waste or cellulosic material substrate
    • C12P7/10—Ethanol, i.e. non-beverage produced as by-product or from waste or cellulosic material substrate substrate containing cellulosic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
    • C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
    • C12Y101/01008—Glycerol-3-phosphate dehydrogenase (NAD+) (1.1.1.8)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y102/00—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2)
    • C12Y102/01—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2) with NAD+ or NADP+ as acceptor (1.2.1)
    • C12Y102/0101—Acetaldehyde dehydrogenase (acetylating) (1.2.1.10)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00—Technologies for the production of fuel of non-fossil origin
    • Y02E50/10—Biofuels, e.g. bio-diesel

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Una célula de levadura que comprende: a) una interrupción de la supresión de uno o más genes nativos de la célula de levadura que codifica(n) una enzima con actividad glicerolfosfato deshidrogenasa (GPD); b) un polinucleótido exógeno que codifica una enzima con actividad aldehído oxidorreductasa, donde el polinucleótido comprende una secuencia de nucleótidos que codifica a una secuencia de aminoácidos que tiene por lo menos un 50% de identidad en la secuencia de aminoácidos con SEQ ID Nº 12. Proceso.A yeast cell comprising: a) an interruption in the suppression of one or more genes native to the yeast cell that encodes (n) an enzyme with glycerol phosphate dehydrogenase (GPD) activity; b) an exogenous polynucleotide that encodes an enzyme with aldehyde oxidoreductase activity, where the polynucleotide comprises a nucleotide sequence that encodes an amino acid sequence that has at least 50% identity in the amino acid sequence with SEQ ID No. 12. Process.

ARP130102995A 2012-08-28 2013-08-23 LIFTS OF LIFTS MODIFIED TO PRODUCE ETHANOL FROM ACETATE AR092217A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP12181938 2012-08-28

Publications (1)

Publication Number Publication Date
AR092217A1 true AR092217A1 (en) 2015-04-08

Family

ID=46963434

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP130102995A AR092217A1 (en) 2012-08-28 2013-08-23 LIFTS OF LIFTS MODIFIED TO PRODUCE ETHANOL FROM ACETATE

Country Status (3)

Country Link
AR (1) AR092217A1 (en)
IN (1) IN2015DN01041A (en)
WO (1) WO2014033018A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104263739A (en) * 2014-10-08 2015-01-07 山东大学 Nucleic acid molecule for encoding xylose translocator and xylose translocator encoded by nucleic acid molecule
EP4055171A1 (en) * 2019-11-08 2022-09-14 DSM IP Assets B.V. Process for producing ethanol

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2679920A1 (en) 1991-08-02 1993-02-05 Rhone Poulenc Rorer Sa Highly stable recombinant yeasts for the production of recombinant proteins, their preparation and their use
WO2003062443A2 (en) 2001-11-08 2003-07-31 Antex Pharma, Inc. Novel substituted alkane compounds and uses thereof
SE0202090D0 (en) 2002-05-08 2002-07-04 Forskarpatent I Syd Ab A modified yeast consuming L-arabinose
ES2586618T3 (en) 2003-05-02 2016-10-17 Cargill, Incorporated Species of genetically modified yeast, and fermentation processes that employ genetically modified yeasts
SE0302421D0 (en) 2003-09-11 2003-09-11 Forskarpatent I Syd Ab Construction of new xylose utilizing Saccharomyces cerevisiae strain
SE0400815D0 (en) 2004-03-26 2004-03-26 Forskarpatent I Syd Ab Traits in recombinant xylose-growing Saccharomyces cerevisiae strains using genome-wide transcription analysis
SE0401303D0 (en) 2004-05-19 2004-05-19 Forskarpatent I Syd Ab Ethanol productivities of microbial strains in fermentation of dilute-acid hydrolyzates depending on their furan reduction capacities
CA2861834A1 (en) 2004-07-16 2006-01-26 Technische Universiteit Delft Metabolic engineering of xylose fermenting eukaryotic cells
US7888489B2 (en) 2005-01-24 2011-02-15 Dsm Ip Assets B.V. Method for producing a compound of interest in a filamentous fungal cell
US8812247B2 (en) 2006-06-29 2014-08-19 Dsm Ip Assets B.V. Method for achieving improved polypeptide expression
EA016303B1 (en) 2006-10-02 2012-04-30 ДСМ АйПи АССЕТС Б.В. Metabolic engineering of arabinose-fermenting yeast cells
US20100304454A1 (en) 2007-07-19 2010-12-02 Royal Nedalco B.V. Novel arabinose-fermenting eukaryotic cells
PL2173881T3 (en) * 2007-07-23 2017-05-31 Dsm Ip Assets B.V. Acetyl-coa producing enzymes in yeast
CN101965401B (en) 2008-03-07 2014-06-04 帝斯曼知识产权资产管理有限公司 A pentose sugar fermenting cell
EP2367928B1 (en) 2008-12-24 2018-03-14 DSM IP Assets B.V. Xylose isomerase genes and their use in fermentation of pentose sugars
EP2277989A1 (en) * 2009-07-24 2011-01-26 Technische Universiteit Delft Fermentative glycerol-free ethanol production
EP2699589A2 (en) * 2011-04-22 2014-02-26 DSM IP Assets B.V. Yeast cell capable of converting sugars including arabinose and xylose

Also Published As

Publication number Publication date
IN2015DN01041A (en) 2015-06-26
WO2014033018A1 (en) 2014-03-06

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