AR089425A1 - Anticuerpo ctgf (factor de crecimiento de tejido conectivo) antihumano - Google Patents
Anticuerpo ctgf (factor de crecimiento de tejido conectivo) antihumanoInfo
- Publication number
- AR089425A1 AR089425A1 ARP120104933A ARP120104933A AR089425A1 AR 089425 A1 AR089425 A1 AR 089425A1 AR P120104933 A ARP120104933 A AR P120104933A AR P120104933 A ARP120104933 A AR P120104933A AR 089425 A1 AR089425 A1 AR 089425A1
- Authority
- AR
- Argentina
- Prior art keywords
- antibody
- human ctgf
- growth factor
- antihuman
- connective tissue
- Prior art date
Links
- 101000777550 Homo sapiens CCN family member 2 Proteins 0.000 title abstract 2
- 239000003102 growth factor Substances 0.000 title abstract 2
- 102100031168 CCN family member 2 Human genes 0.000 title 1
- 210000002808 connective tissue Anatomy 0.000 title 1
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 2
- 208000007342 Diabetic Nephropathies Diseases 0.000 abstract 1
- 230000027455 binding Effects 0.000 abstract 1
- 208000020832 chronic kidney disease Diseases 0.000 abstract 1
- 208000033679 diabetic kidney disease Diseases 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000012010 growth Effects 0.000 abstract 1
- 102000047612 human CCN2 Human genes 0.000 abstract 1
- 208000017169 kidney disease Diseases 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 238000006386 neutralization reaction Methods 0.000 abstract 1
- 230000008506 pathogenesis Effects 0.000 abstract 1
- 102000040430 polynucleotide Human genes 0.000 abstract 1
- 108091033319 polynucleotide Proteins 0.000 abstract 1
- 239000002157 polynucleotide Substances 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 230000008467 tissue growth Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/40—Immunoglobulins specific features characterized by post-translational modification
- C07K2317/41—Glycosylation, sialylation, or fucosylation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Urology & Nephrology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2011281811 | 2011-12-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR089425A1 true AR089425A1 (es) | 2014-08-20 |
Family
ID=48668601
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP120104933A AR089425A1 (es) | 2011-12-22 | 2012-12-21 | Anticuerpo ctgf (factor de crecimiento de tejido conectivo) antihumano |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US9587015B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP2796550B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP6040943B2 (cg-RX-API-DMAC7.html) |
| KR (1) | KR20140107507A (cg-RX-API-DMAC7.html) |
| CN (1) | CN104011206B (cg-RX-API-DMAC7.html) |
| AR (1) | AR089425A1 (cg-RX-API-DMAC7.html) |
| BR (1) | BR112014015405A2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2859627A1 (cg-RX-API-DMAC7.html) |
| EA (1) | EA029290B1 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2665851T3 (cg-RX-API-DMAC7.html) |
| IN (1) | IN2014CN04615A (cg-RX-API-DMAC7.html) |
| MX (1) | MX345019B (cg-RX-API-DMAC7.html) |
| PL (1) | PL2796550T3 (cg-RX-API-DMAC7.html) |
| PT (1) | PT2796550T (cg-RX-API-DMAC7.html) |
| TW (1) | TW201333034A (cg-RX-API-DMAC7.html) |
| WO (1) | WO2013094723A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109824777A (zh) * | 2019-03-15 | 2019-05-31 | 辽宁何氏医学院 | 一种具有抑制玻璃体视网膜纤维化病变作用的单克隆抗体及其制备方法和应用 |
| US20200369759A1 (en) | 2019-05-23 | 2020-11-26 | Fibrogen, Inc. | Methods of treatment of muscular dystrophies |
| US20220324953A1 (en) * | 2019-06-04 | 2022-10-13 | Jiangsu Hengrui Medicine Co., Ltd. | Anti-connective tissue growth factor antibody and application thereof |
| KR20230117161A (ko) * | 2020-12-03 | 2023-08-07 | 지앙수 헨그루이 파마슈티컬스 컴퍼니 리미티드 | 항-결합 조직 성장 인자 항체를 포함하는 약학 조성물 |
| EP4537841A1 (en) | 2022-06-07 | 2025-04-16 | Astellas Pharma, Inc. | Pharmaceutical composition containing anti-integrin alpha-11 antibody for treatment or prevention of aging-related diseases |
| TW202434302A (zh) | 2022-10-31 | 2024-09-01 | 日商安斯泰來製藥股份有限公司 | 包含類鐸受體７／８雙重促效劑化合物之抗體藥物複合體 |
| WO2024188179A1 (zh) * | 2023-03-10 | 2024-09-19 | 上海济煜医药科技有限公司 | 一种靶向ctgf的抗体或其抗原结合片段及其应用 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE8808645U1 (de) | 1988-07-06 | 1988-08-25 | Hofer, Daniel, 7730 Villingen-Schwenningen | Anzeigeeinrichtung für Feuerlöscher |
| AU681633B2 (en) | 1993-03-11 | 1997-09-04 | Juridical Foundation The Chemo-Sero-Therapeutic Research Institute | Anti-HIV monoclonal antibody |
| WO1999033878A1 (en) * | 1997-12-25 | 1999-07-08 | Japan Tobacco Inc. | Monoclonal antibody against connective tissue growth factor and medicinal uses thereof |
| JP4537507B2 (ja) | 1997-12-25 | 2010-09-01 | アムジェン インコーポレイテッド | 結合組織増殖因子に対するモノクローナル抗体及びその医薬用途 |
| EP1140964B1 (en) * | 1998-12-14 | 2008-04-09 | University Of Miami | Connective tissue growth factor (ctgf) fragment |
| US7115390B1 (en) | 1998-12-14 | 2006-10-03 | Fibrogen, Inc. | Connective tissue growth factor fragments and methods and uses thereof |
| US6596541B2 (en) | 2000-10-31 | 2003-07-22 | Regeneron Pharmaceuticals, Inc. | Methods of modifying eukaryotic cells |
| US7405274B2 (en) * | 2003-06-04 | 2008-07-29 | Fibrogen, Inc. | Connective tissue growth factor antibodies |
| JP2009067678A (ja) * | 2005-12-07 | 2009-04-02 | Nihon Nosan Kogyo Kk | 結合組織増殖因子に対する抗体又はそれを含む組成物 |
| US7608693B2 (en) | 2006-10-02 | 2009-10-27 | Regeneron Pharmaceuticals, Inc. | High affinity human antibodies to human IL-4 receptor |
-
2012
- 2012-12-21 KR KR1020147020039A patent/KR20140107507A/ko not_active Abandoned
- 2012-12-21 IN IN4615CHN2014 patent/IN2014CN04615A/en unknown
- 2012-12-21 ES ES12860742.1T patent/ES2665851T3/es active Active
- 2012-12-21 CA CA2859627A patent/CA2859627A1/en not_active Abandoned
- 2012-12-21 MX MX2014007681A patent/MX345019B/es active IP Right Grant
- 2012-12-21 EP EP12860742.1A patent/EP2796550B1/en active Active
- 2012-12-21 EA EA201491240A patent/EA029290B1/ru not_active IP Right Cessation
- 2012-12-21 AR ARP120104933A patent/AR089425A1/es unknown
- 2012-12-21 WO PCT/JP2012/083206 patent/WO2013094723A1/ja not_active Ceased
- 2012-12-21 PL PL12860742T patent/PL2796550T3/pl unknown
- 2012-12-21 US US14/367,081 patent/US9587015B2/en not_active Expired - Fee Related
- 2012-12-21 PT PT128607421T patent/PT2796550T/pt unknown
- 2012-12-21 JP JP2013550349A patent/JP6040943B2/ja not_active Expired - Fee Related
- 2012-12-21 BR BR112014015405A patent/BR112014015405A2/pt unknown
- 2012-12-21 TW TW101148989A patent/TW201333034A/zh unknown
- 2012-12-21 CN CN201280063995.5A patent/CN104011206B/zh not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CA2859627A1 (en) | 2013-06-27 |
| EP2796550A4 (en) | 2015-08-19 |
| MX345019B (es) | 2017-01-11 |
| JP6040943B2 (ja) | 2016-12-07 |
| CN104011206A (zh) | 2014-08-27 |
| ES2665851T3 (es) | 2018-04-27 |
| PT2796550T (pt) | 2018-04-18 |
| TW201333034A (zh) | 2013-08-16 |
| CN104011206B (zh) | 2017-03-08 |
| IN2014CN04615A (cg-RX-API-DMAC7.html) | 2015-09-18 |
| KR20140107507A (ko) | 2014-09-04 |
| EP2796550A1 (en) | 2014-10-29 |
| BR112014015405A2 (pt) | 2017-06-13 |
| US20140343258A1 (en) | 2014-11-20 |
| JPWO2013094723A1 (ja) | 2015-04-27 |
| WO2013094723A1 (ja) | 2013-06-27 |
| US9587015B2 (en) | 2017-03-07 |
| EP2796550B1 (en) | 2018-02-28 |
| PL2796550T3 (pl) | 2018-08-31 |
| MX2014007681A (es) | 2014-11-25 |
| EA029290B1 (ru) | 2018-03-30 |
| EA201491240A1 (ru) | 2014-11-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |