AR080242A1 - VETERINARY COMPOSITIONS. APPLICATIONS. - Google Patents
VETERINARY COMPOSITIONS. APPLICATIONS.Info
- Publication number
- AR080242A1 AR080242A1 ARP110100535A ARP110100535A AR080242A1 AR 080242 A1 AR080242 A1 AR 080242A1 AR P110100535 A ARP110100535 A AR P110100535A AR P110100535 A ARP110100535 A AR P110100535A AR 080242 A1 AR080242 A1 AR 080242A1
- Authority
- AR
- Argentina
- Prior art keywords
- composition according
- bioactive agent
- polymer
- amount
- veterinary
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid, pantothenic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/429—Thiazoles condensed with heterocyclic ring systems
- A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0065—Forms with gastric retention, e.g. floating on gastric juice, adhering to gastric mucosa, expanding to prevent passage through the pylorus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Abstract
Reivindicacion 1: Una composicion veterinaria de liberacion controlada en forma de un comprimido que puede administrarse por vía oral que comprende: (a) al menos un agente bioactivo para uso veterinario: (b) un polímero que tiene un peso molecular desde aproximadamente 10 1.000.000 hasta aproximadamente 9.000.000 dalton, o un polímero que tiene una viscosidad en un intervalo de desde aproximadamente 80.000 hasta aproximadamente 120.000 mPa.s, en una cantidad de aproximadamente el 5% a aproximadamente el 60% del peso total del comprimido; y (c) al menos un agente disgregante en una cantidad entre 15 aproximadamente el 10% y aproximadamente el 50% del peso total del comprimido. Reivindicacion 13: La composicion, segun la reivindicacion 1, en la que el agente disgregante se selecciona de un grupo que consiste en croscarmelosa sodica, carboximetilalmidon de sodio, povidona reticulada y 2- hidroxipropil éter (poco sustituido) Reivindicacion 19: La composicion segun la reivindicacion 1, en la que el agente bioactivo es un compuesto de formula 1 o una sal aceptable del mismo en la que R1 es alquilo -C14, opcionalmente sustituido con hidroxilo. Reivindicacion 20: La composicion segun la reivindicacion 1, en la que el agente bioactivo es pregabalina, amoxicilina o tramadol.Claim 1: A veterinary controlled release composition in the form of a tablet that can be administered orally comprising: (a) at least one bioactive agent for veterinary use: (b) a polymer having a molecular weight from about 10 1,000. 000 to about 9,000,000 dalton, or a polymer having a viscosity in a range of from about 80,000 to about 120,000 mPa.s, in an amount of about 5% to about 60% of the total tablet weight; and (c) at least one disintegrating agent in an amount between about 10% and about 50% of the total tablet weight. Claim 13: The composition according to claim 1, wherein the disintegrating agent is selected from a group consisting of croscarmellose sodium, sodium carboxymethyl starch, crosslinked povidone and 2-hydroxypropyl ether (poorly substituted) Claim 19: The composition according to claim 1, wherein the bioactive agent is a compound of formula 1 or an acceptable salt thereof wherein R1 is -C14 alkyl, optionally substituted with hydroxyl. Claim 20: The composition according to claim 1, wherein the bioactive agent is pregabalin, amoxicillin or tramadol.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US30771310P | 2010-02-24 | 2010-02-24 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR080242A1 true AR080242A1 (en) | 2012-03-21 |
Family
ID=43877280
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP110100535A AR080242A1 (en) | 2010-02-24 | 2011-02-22 | VETERINARY COMPOSITIONS. APPLICATIONS. |
Country Status (13)
Country | Link |
---|---|
US (2) | US20120322782A1 (en) |
EP (1) | EP2538926A2 (en) |
JP (1) | JP2011173881A (en) |
KR (1) | KR101484382B1 (en) |
CN (2) | CN104224737A (en) |
AR (1) | AR080242A1 (en) |
AU (1) | AU2011219452B2 (en) |
BR (1) | BR112012020989A2 (en) |
CA (1) | CA2788659C (en) |
HK (1) | HK1178072A1 (en) |
MX (1) | MX2012009798A (en) |
NZ (2) | NZ601450A (en) |
WO (1) | WO2011104652A2 (en) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2538926A2 (en) * | 2010-02-24 | 2013-01-02 | Pfizer Inc. | Veterinary compositions |
DK3290421T3 (en) | 2013-02-22 | 2019-03-18 | Pfizer | COMBINATION OF PYRROLO [2, 3-D] PYRIMIDINE DERIVATIVES AND ONE OR MORE ADDITIONAL SUBSTANCES AS JANUS-RELATED KINASES (JAK) INHIBITORS |
EP3180344B1 (en) | 2014-08-12 | 2019-09-18 | Pfizer Inc | Pyrrolo[2,3-d]pyrimidine derivatives useful for inhibiting janus kinase |
CA2961410C (en) | 2014-09-16 | 2023-07-11 | India Globalization Capital, Inc. | Cannabinoid composition and method for treating pain |
CN104546759A (en) * | 2014-12-25 | 2015-04-29 | 海南卫康制药(潜山)有限公司 | Primidone composition lyophilized tablet and preparation method thereof |
EP3247359A4 (en) | 2015-01-25 | 2018-08-08 | India Globalization Capital, Inc. | Composition and method for treating seizure disorders |
US10596159B2 (en) | 2015-08-12 | 2020-03-24 | India Globalization Capital, Inc. | Method and composition for treating cachexia and eating disorders |
WO2017142740A1 (en) * | 2016-02-16 | 2017-08-24 | Zoetis Services Llc | Process for preparing 7h-pyrrolo [2, 3-d] pyrimidine compounds |
EP3470065A4 (en) | 2016-06-09 | 2020-03-18 | DS Pharma Animal Health Co. Ltd. | Sustained-release preparation composition for animals |
EP3471746A4 (en) | 2016-06-15 | 2020-02-26 | India Globalization Capital, Inc. | Method and composition for treating seizure disorders |
CN108210476A (en) * | 2016-12-19 | 2018-06-29 | 湖南尔康制药股份有限公司 | Chloramphenicol starch capsule of gastric retention floating and preparation method thereof |
CN106580887A (en) * | 2017-01-02 | 2017-04-26 | 江苏恒丰强生物技术有限公司 | Marbofloxacin soluble pulvis |
JP6919119B2 (en) * | 2017-01-23 | 2021-08-18 | 日新製薬株式会社 | A compressed solid pharmaceutical composition containing a γ-aminobutyric acid derivative substituted at the 3-position. |
Family Cites Families (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PT661045E (en) * | 1992-09-18 | 2002-11-29 | Yamanouchi Pharma Co Ltd | PREPARATION IN HYDROGEL OF PROLONGED LIBERATION |
US20090060995A1 (en) * | 2005-01-13 | 2009-03-05 | Kamalinder Kaur Singh | Dispersible sustained release pharmaceutical compositions |
EE05022B1 (en) * | 1999-03-31 | 2008-06-16 | Janssen Pharmaceutica N.V. | Use of Pregelatinised Starch in a Hydrophilic Controlled Release Preparation and a Hydrophilic Controlled Release Preparation |
US6488962B1 (en) * | 2000-06-20 | 2002-12-03 | Depomed, Inc. | Tablet shapes to enhance gastric retention of swellable controlled-release oral dosage forms |
US7674480B2 (en) * | 2000-06-23 | 2010-03-09 | Teva Pharmaceutical Industries Ltd. | Rapidly expanding composition for gastric retention and controlled release of therapeutic agents, and dosage forms including the composition |
ATE423120T1 (en) * | 2000-06-26 | 2009-03-15 | Pfizer Prod Inc | PYRROLOÄ2,3-DÜPYRIMIDINE COMPOUNDS AS IMMUNOSUPPRESSIVE ACTIVES |
US6723340B2 (en) * | 2001-10-25 | 2004-04-20 | Depomed, Inc. | Optimal polymer mixtures for gastric retentive tablets |
US20030091630A1 (en) * | 2001-10-25 | 2003-05-15 | Jenny Louie-Helm | Formulation of an erodible, gastric retentive oral dosage form using in vitro disintegration test data |
AU2003230189A1 (en) * | 2003-01-29 | 2004-08-23 | Nitin Bhalachandra Dharmadhikari | Oral controlled release pharmaceutical composition containing metaxalone as active agent |
SI1596841T1 (en) * | 2003-02-21 | 2009-06-30 | Lek Pharmaceuticals D.D. | Therapeutic system comprising amoxicillin and clavulanic acid |
US8097614B2 (en) * | 2005-02-17 | 2012-01-17 | Velcera Pharmaceuticals, Inc. | Transmucosal administration of meloxicam compositions for treating and preventing disorders in non-human domesticated animals |
KR20080039400A (en) * | 2005-07-07 | 2008-05-07 | 파남 컴퍼니스 인크. | Sustained release pharmaceutical compositions for highly water soluble drugs |
PL116330U1 (en) * | 2005-10-31 | 2007-04-02 | Alza Corp | Method for the reduction of alcohol provoked rapid increase in the released dose of the orally administered opioide with prolonged liberation |
CN1957909B (en) * | 2005-10-31 | 2013-09-11 | 阿尔扎公司 | Methods of reducing alcohol-induced dose dumping for opioid sustained release oral dosage forms |
NL2000281C2 (en) * | 2005-11-02 | 2007-08-07 | Pfizer Prod Inc | Solid pharmaceutical compositions containing pregabalin. |
CA2635594A1 (en) * | 2005-12-30 | 2007-07-12 | Advancis Pharmaceutical Corporation | Gastric release pulse system for drug delivery |
WO2009114648A1 (en) * | 2008-03-11 | 2009-09-17 | Depomed Inc. | Gastric retentive extended-release dosage forms comprising combinations of a non-opioid analgesic and an opioid analgesic |
SI2384326T1 (en) * | 2008-08-20 | 2014-06-30 | Zoetis Llc | Pyrrološ2,3-dćpyrimidine compounds |
EP2538926A2 (en) * | 2010-02-24 | 2013-01-02 | Pfizer Inc. | Veterinary compositions |
-
2011
- 2011-02-15 EP EP11708328A patent/EP2538926A2/en not_active Withdrawn
- 2011-02-15 KR KR1020127024728A patent/KR101484382B1/en not_active IP Right Cessation
- 2011-02-15 AU AU2011219452A patent/AU2011219452B2/en not_active Ceased
- 2011-02-15 WO PCT/IB2011/050625 patent/WO2011104652A2/en active Application Filing
- 2011-02-15 US US13/580,156 patent/US20120322782A1/en not_active Abandoned
- 2011-02-15 NZ NZ601450A patent/NZ601450A/en not_active IP Right Cessation
- 2011-02-15 MX MX2012009798A patent/MX2012009798A/en unknown
- 2011-02-15 NZ NZ629036A patent/NZ629036A/en not_active IP Right Cessation
- 2011-02-15 CA CA2788659A patent/CA2788659C/en not_active Expired - Fee Related
- 2011-02-15 CN CN201410419782.2A patent/CN104224737A/en active Pending
- 2011-02-15 BR BR112012020989A patent/BR112012020989A2/en not_active IP Right Cessation
- 2011-02-15 CN CN201180011241.0A patent/CN102781431B/en not_active Expired - Fee Related
- 2011-02-22 JP JP2011036219A patent/JP2011173881A/en active Pending
- 2011-02-22 AR ARP110100535A patent/AR080242A1/en not_active Application Discontinuation
-
2013
- 2013-04-30 HK HK13105206.4A patent/HK1178072A1/en not_active IP Right Cessation
-
2014
- 2014-08-06 US US14/452,862 patent/US20150080361A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
BR112012020989A2 (en) | 2016-05-03 |
WO2011104652A3 (en) | 2011-11-10 |
NZ629036A (en) | 2014-09-26 |
US20150080361A1 (en) | 2015-03-19 |
MX2012009798A (en) | 2012-09-12 |
WO2011104652A2 (en) | 2011-09-01 |
KR20120137374A (en) | 2012-12-20 |
CN102781431A (en) | 2012-11-14 |
AU2011219452A1 (en) | 2012-08-23 |
CN102781431B (en) | 2014-08-27 |
US20120322782A1 (en) | 2012-12-20 |
CN104224737A (en) | 2014-12-24 |
KR101484382B1 (en) | 2015-01-19 |
NZ601450A (en) | 2014-09-26 |
CA2788659C (en) | 2015-05-05 |
CA2788659A1 (en) | 2011-09-01 |
HK1178072A1 (en) | 2013-09-06 |
AU2011219452B2 (en) | 2014-05-29 |
EP2538926A2 (en) | 2013-01-02 |
JP2011173881A (en) | 2011-09-08 |
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