AR079425A1 - INSECTICIDE METHODS USING PIRIDINE COMPOUNDS - Google Patents

INSECTICIDE METHODS USING PIRIDINE COMPOUNDS

Info

Publication number
AR079425A1
AR079425A1 ARP100104204A ARP100104204A AR079425A1 AR 079425 A1 AR079425 A1 AR 079425A1 AR P100104204 A ARP100104204 A AR P100104204A AR P100104204 A ARP100104204 A AR P100104204A AR 079425 A1 AR079425 A1 AR 079425A1
Authority
AR
Argentina
Prior art keywords
alkyl
formula
group
haloalkyl
alkoxy
Prior art date
Application number
ARP100104204A
Other languages
Spanish (es)
Original Assignee
Basf Se
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Se filed Critical Basf Se
Publication of AR079425A1 publication Critical patent/AR079425A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/02—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having no bond to a nitrogen atom
    • A01N47/06—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having no bond to a nitrogen atom containing —O—CO—O— groups; Thio analogues thereof
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
    • A01N47/10—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof
    • A01N47/22—O-Aryl or S-Aryl esters thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems

Abstract

Reivindicacion 1: Un método para combatir o controlar insectos, arácnidos o nemátodos que comprende poner en contacto un insecto, arácnido o nemátodo o su suministro de alimento, hábitat o área de reproduccion con un compuesto de formula (1) o una composicion caracterizada porque comprende al menos un compuesto de la formula (1), en donde: A, E, G, M son N o C-Rc, en donde siendo uno de estos grupos N, y en donde Rc es, de modo independiente entre sí, hidrogeno o está seleccionado de Rb, y en donde Rb está seleccionado, de modo independiente entre sí, de Z-CN, Z-OH, Z-NO2, Z-halogeno, alquilo C1-8, haloalquilo C1-4, alquenilo C2-8, alquinilo C2-8, Z-alcoxi C1-8, Z-haloalcoxi C1-8, Z-cicloalquilo C3-10, O-Z-cicloalquilo C3-10, Z-C(=O)-Ra, NRiRii, Z-(tri-alquil C1-4)sililo, Z-fenilo y S(O)nRbb, en donde Ra está seleccionado de hidrogeno, OH, alquilo C1-8, haloalquilo C1-4, Z-cicloalquilo C3-6, alquenilo C2-8, Z-cicloalquenilo C5-6, alquinilo C2-8, Z-alcoxi C1-6, Z-haloalcoxi C1-4, Z-alqueniloxi C3-8, Z-alquiniloxi C3-8, NRiRii, alquilsulfonilo C1-6, Z-(tri-alquil C1-4)sililo, Z-fenilo, Z-fenoxi, Z-fenilamino, un heterociclo monocíclico de 5 o 6 miembros o bicíclico de 9 o 10 miembros que contiene 1, 2, 3 o 4 heteroátomos seleccionados del grupo que consiste en O, N y S, en donde los grupos cíclicos están no sustituidos o sustituidos por 1, 2, 3 o 4 átomos de halogeno y/o grupos Rbb, en donde Ri, Rii están seleccionados, de modo independiente entre sí, de hidrogeno, alquilo C1-8, haloalquilo C1-4, alquenilo C3-8, alquinilo C3-8, Z-cicloalquilo C3-6, Z-alcoxi C1-8, Z-haloalcoxi C1-8, Z-C(=O)Rbb, Z-fenilo, un heterociclo aromático saturado o insaturado monocíclico de 3 a 7 miembros o bicíclico de 9 o 10 miembros que contiene 1, 2, 3 o 4 heteroátomos seleccionados del grupo que consiste en O, N y S, unido a través de Z, o en donde Ri y Rii junto con el átomo de nitrogeno al que están unidos también pueden formar un heterociclo monocíclico de 5 o 6 miembros o bicíclico de 9 o 10 miembros que contiene 1, 2, 3 o 4 heteroátomos seleccionados del grupo que consiste en O, N y S; Rbb es alquilo C1-8 o haloalquilo C1-6; y Z es un enlace covalente o cadena de alquileno C1-4; o en donde Rb junto con el grupo Rb opcionalmente unido al átomo de carbono adyacente también puede formar un anillo saturado o parcial o totalmente insaturado de 5 o 6 miembros que, además de átomos de carbono, también puede contener 1, 2 o 3 heteroátomos seleccionados del grupo que consiste en O, N y S; X, Y están seleccionados de O, S o N-R3; R1 es O-RA, S(O)n-RA o OS(O)n-RA; en donde n es 0, 1 o 2; y RA está seleccionado de hidrogeno, alquilo C1-4, Z-cicloalquilo C3-6, haloalquilo C1-4, alquenilo C2-6, Z-cicloalquenilo C3-6, alquinilo C2-6, Z-(tri-alquil C1-4)sililo, Z-C(=O)-Ra, Z-P(=O)(Ra)2, Z-NRi-C(O)-NRiRii, NRiRii, un heterociclo aromático saturado o insaturado monocíclico de 3 a 7 miembros o bicíclico de 9 o 10 miembros que contiene 1, 2, 3 o 4 heteroátomos seleccionados del grupo que consiste en O, N y S, que puede estar unido a través del átomo de carbono o nitrogeno, y que puede estar parcial o totalmente sustituido con grupos seleccionados de Ra y/o Rb; R2 está seleccionado de fenilo, naftilo, un heterociclo aromático monocíclico de 5 o 6 miembros o bicíclico de 9 o 10 miembros que contiene 1, 2, 3 o 4 heteroátomos seleccionados del grupo que consiste en O, N y S, y en donde los grupos cíclicos están no sustituidos o sustituidos por 1, 2, 3 o 4 grupos Rb; R3 está seleccionado de hidrogeno, alquilo C1-6, haloalquilo C1-4, alquenilo C2-6, alquinilo C3-6, Z-cicloalquilo C3-10, alcoxi C1-6-alquilo C1-6, cianoalquilo C1-6, Z-fenilo, un heterociclo monocíclico de 5 o 6 miembros unido a través de Z, que contiene 1, 2, 3 o 4 heteroátomos seleccionados del grupo que consiste en O, N y S y que puede estar unido a través de un átomo de carbono o de nitrogeno del heterociclo y en donde el heterociclo puede estar total o parcialmente sustituido con Rb, Z-C(=O)-Ra2 o tri-alquil C1-4sililo, en donde Ra2 está seleccionado de alquilo C1-6, haloalquilo C1-4, Z-alcoxi C1-6, Z-haloalcoxi C1-4 o NRiRii; y en donde en los grupos RA, R3 y sus sustituyentes, las cadenas de carbono y/o los grupos cíclicos pueden estar parcial o totalmente sustituidos con grupos Rb; y/o al menos un N-oxido, un enantiomero, diastereomero o sus sales aceptables en agricultura o veterinaria. Reivindicacion 4: Un método para tratar, controlar, prevenir o proteger animales contra la infestacion o infeccion por parásitos al administrar o aplicar en forma oral, topica o parenteral a los animales un compuesto de la formula (1) o una composicion caracterizado porque comprende al menos un compuesto de la formula (1) tal como se ha definido en la reivindicacion 1, y/o al menos un N-oxido, un enantiomero, diastereomero o su sal aceptable en veterinaria. Reivindicacion 13: Un método de acuerdo con cualquiera de las reivindicaciones 1 a 5, caracterizado porque en la formula (1), A es N; X es O; Y es O o S; y E, G, M es C-Rc, y en donde Rc es hidrogeno o está seleccionado de Rb tal como se ha definido en la reivindicacion 1. Reivindicacion 15: Un compuesto de la formula (1), caracterizado porque tiene la formula (2), en donde: Y es S u O; X es S u O; R1 es tal como se ha definido en la formula (1) de la reivindicacion 5; y Rc2, Rc3, Rc3', Rc4, Rc4' y Rc5' se seleccionan, de modo independiente entre sí, del grupo que consiste en hidrogeno, OH, CN, NO2, halogeno, alquilo C1-4, haloalquilo C1-4, alcoxi C1-4 y haloalcoxi C1-4; y/o al menos un N-oxido, un enantiomero, diastereomero o su sal aceptable en la agricultura o veterinaria. Reivindicacion 16: Un compuesto de la formula (1), caracterizado porque tiene la formula (3), en donde: X es tal como se ha definido en la formula (1) de la reivindicacion 1; R1 es tal como se ha definido en la formula (1) de la reivindicacion 5; R2 es fenilo o piridilo, que puede llevar uno o más sustituyentes seleccionados del grupo que consiste en OH, CN, NO2, halogeno, alquilo C1-4, haloalquilo C1-4, alcoxi C1-4 y haloalcoxi C1-4; Rc2, Rc3, Rc4 se seleccionan, de modo independiente entre sí, del grupo que consiste en hidrogeno, OH, CN, NO2, halogeno, alquilo C1-4, haloalquilo C1-4, alcoxi C1-4 y haloalcoxi C1-4; y R3 es un heterociclo monocíclico de 5 o 6 miembros unido a través de Z y seleccionado del grupo que consiste en piridilo, tiazolilo, isotiazolilo, pirazolilo, oxazolilo y isoxazolilo, en donde el heterociclo puede estar unido a través de un átomo de carbono o de nitrogeno del heterociclo y que puede llevar uno o más sustituyentes seleccionados del grupo que consiste en OH, CN, NO2, halogeno, alquilo C1-4, haloalquilo C1-4, alcoxi C1-4 y haloalcoxi C1-4; Z es un enlace covalente o cadena de alquileno C1-4, en donde la cadena de carbono opcionalmente puede llevar uno o más sustituyentes seleccionados de alquilo C1-8 o haloalquilo C1-4; y/o al menos un N-oxido, un enantiomero, diastereomero o su sal aceptable en agricultura o veterinaria. Reivindicacion 17: Un composicion agrícola o veterinaria caracterizado porque comprende al menos un compuesto de la formula (1) de acuerdo con cualquiera de las reivindicaciones 1 o 5 a 16, o un N-oxido, enantiomero, diastereomero o su sal aceptable en la agricultura o veterinaria y al menos un portador líquido y/o solido inerte.Claim 1: A method for combating or controlling insects, arachnids or nematodes comprising contacting an insect, arachnid or nematode or its food supply, habitat or breeding area with a compound of formula (1) or a composition characterized in that it comprises at least one compound of the formula (1), wherein: A, E, G, M are N or C-Rc, where being one of these groups N, and where Rc is, independently of each other, hydrogen or is selected from Rb, and where Rb is independently selected from Z-CN, Z-OH, Z-NO2, Z-halogen, C1-8 alkyl, C1-4 haloalkyl, C2-8 alkenyl , C2-8 alkynyl, Z- C1-8 alkoxy, C1-8 haloalkoxy, C3-10 cycloalkyl, C3-10 OZ-cycloalkyl, ZC (= O) -Ra, NRiRii, Z- (tri-alkyl C1-4) silyl, Z-phenyl and S (O) nRbb, where Ra is selected from hydrogen, OH, C1-8 alkyl, C1-4 haloalkyl, Z3-6 cycloalkyl, C2-8 alkenyl, Z- C5-6 cycloalkenyl, C2-8 alkynyl, Z- C1-6 alkoxy, Z-haloalkoxy C1-4, Z-C3-8 alkenyloxy, Z3-8 alkynyloxy, NRiRii, C1-6 alkylsulfonyl, Z- (tri-C1-4 alkyl) silyl, Z-phenyl, Z-phenoxy, Z-phenylamino, a 5 or 6 member monocyclic heterocycle or 9 or 10 member bicyclic containing 1, 2, 3 or 4 heteroatoms selected from the group consisting of O, N and S, where the cyclic groups are unsubstituted or substituted by 1, 2 , 3 or 4 halogen atoms and / or Rbb groups, wherein Ri, Rii are independently selected from hydrogen, C1-8 alkyl, C1-4 haloalkyl, C3-8 alkenyl, C3-8 alkynyl, Z3-6 cycloalkyl, C1-8 Z-alkoxy, C1-8 haloalkoxy, ZC (= O) Rbb, Z-phenyl, a 3- to 7-membered monocyclic saturated or unsaturated aromatic heterocycle or 9 or 10 bicyclic members containing 1, 2, 3 or 4 heteroatoms selected from the group consisting of O, N and S, linked through Z, or where Ri and Rii together with the nitrogen atom to which they are attached can also form a heterocycle 5 monocyclic or 6 members or bicyclic of 9 or 10 members containing 1, 2, 3 or 4 heteroatoms selected from the group consisting of O, N and S; Rbb is C1-8 alkyl or C1-6 haloalkyl; and Z is a covalent bond or C1-4 alkylene chain; or wherein Rb together with the group Rb optionally attached to the adjacent carbon atom can also form a saturated or partially or totally unsaturated ring of 5 or 6 members which, in addition to carbon atoms, can also contain 1, 2 or 3 heteroatoms selected from the group consisting of O, N and S; X, Y are selected from O, S or N-R3; R1 is O-RA, S (O) n-RA or OS (O) n-RA; where n is 0, 1 or 2; and RA is selected from hydrogen, C 1-4 alkyl, C 3-6 cycloalkyl, C 1-4 haloalkyl, C 2-6 alkenyl, C 3-6 Z-cycloalkenyl, C 2-6 alkynyl, Z- (tri-C 1-4 alkyl ) silyl, ZC (= O) -Ra, ZP (= O) (Ra) 2, Z-NRi-C (O) -NRiRii, NRiRii, a 3- to 7-membered monocyclic saturated or unsaturated aromatic heterocycle or bicyclic 9 or 10 members containing 1, 2, 3 or 4 heteroatoms selected from the group consisting of O, N and S, which may be linked through the carbon or nitrogen atom, and which may be partially or totally substituted with selected groups of Ra and / or Rb; R2 is selected from phenyl, naphthyl, a 5- or 6-membered monocyclic aromatic heterocycle or 9 or 10-membered bicyclic containing 1, 2, 3 or 4 heteroatoms selected from the group consisting of O, N and S, and wherein cyclic groups are unsubstituted or substituted by 1, 2, 3 or 4 Rb groups; R3 is selected from hydrogen, C1-6 alkyl, C1-4 haloalkyl, C2-6 alkenyl, C3-6 alkynyl, Z3-10 cycloalkyl, C1-6 alkoxy-C1-6 alkyl, C1-6 cyanoalkyl, Z- phenyl, a 5 or 6 membered monocyclic heterocycle linked through Z, containing 1, 2, 3 or 4 heteroatoms selected from the group consisting of O, N and S and which may be linked through a carbon atom or of nitrogen of the heterocycle and wherein the heterocycle can be totally or partially substituted with Rb, ZC (= O) -Ra2 or tri-C 1-4 alkyl, wherein Ra 2 is selected from C 1-6 alkyl, C 1-4 haloalkyl, Z C1-6 alkoxy, C1-4 Z-haloalkoxy or NRiRii; and wherein in the RA, R3 groups and their substituents, the carbon chains and / or the cyclic groups may be partially or totally substituted with Rb groups; and / or at least one N-oxide, an enantiomer, diastereomer or its acceptable salts in agriculture or veterinary. Claim 4: A method for treating, controlling, preventing or protecting animals against infestation or infection by parasites by administering or applying orally, topically or parenterally to animals a compound of the formula (1) or a composition characterized in that it comprises less a compound of the formula (1) as defined in claim 1, and / or at least one N-oxide, an enantiomer, diastereomer or its veterinary acceptable salt. Claim 13: A method according to any one of claims 1 to 5, characterized in that in the formula (1), A is N; X is O; Y is O or S; and E, G, M is C-Rc, and wherein Rc is hydrogen or is selected from Rb as defined in claim 1. Claim 15: A compound of the formula (1), characterized in that it has the formula ( 2), where: Y is S or O; X is S or O; R1 is as defined in the formula (1) of claim 5; and Rc2, Rc3, Rc3 ', Rc4, Rc4' and Rc5 'are independently selected from the group consisting of hydrogen, OH, CN, NO2, halogen, C1-4 alkyl, C1-4 haloalkyl, alkoxy C1-4 and C1-4 haloalkoxy; and / or at least one N-oxide, an enantiomer, diastereomer or its acceptable salt in agriculture or veterinary. Claim 16: A compound of the formula (1), characterized in that it has the formula (3), wherein: X is as defined in the formula (1) of claim 1; R1 is as defined in the formula (1) of claim 5; R2 is phenyl or pyridyl, which may carry one or more substituents selected from the group consisting of OH, CN, NO2, halogen, C1-4 alkyl, C1-4 haloalkyl, C1-4 alkoxy and C1-4 haloalkoxy; Rc2, Rc3, Rc4 are independently selected from the group consisting of hydrogen, OH, CN, NO2, halogen, C1-4 alkyl, C1-4 haloalkyl, C1-4 alkoxy and C1-4 haloalkoxy; and R3 is a 5- or 6-membered monocyclic heterocycle attached through Z and selected from the group consisting of pyridyl, thiazolyl, isothiazolyl, pyrazolyl, oxazolyl and isoxazolyl, wherein the heterocycle may be attached through a carbon atom or of heterocycle nitrogen and which can carry one or more substituents selected from the group consisting of OH, CN, NO2, halogen, C1-4 alkyl, C1-4 haloalkyl, C1-4 alkoxy and C1-4 haloalkoxy; Z is a covalent bond or C1-4 alkylene chain, wherein the carbon chain may optionally carry one or more substituents selected from C1-8 alkyl or C1-4 haloalkyl; and / or at least one N-oxide, an enantiomer, diastereomer or its acceptable salt in agriculture or veterinary. Claim 17: An agricultural or veterinary composition characterized in that it comprises at least one compound of the formula (1) according to any one of claims 1 or 5 to 16, or an N-oxide, enantiomer, diastereomer or its salt acceptable in agriculture or veterinary and at least one liquid carrier and / or solid inert.

ARP100104204A 2009-11-12 2010-11-12 INSECTICIDE METHODS USING PIRIDINE COMPOUNDS AR079425A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US26042309P 2009-11-12 2009-11-12

Publications (1)

Publication Number Publication Date
AR079425A1 true AR079425A1 (en) 2012-01-25

Family

ID=43466749

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP100104204A AR079425A1 (en) 2009-11-12 2010-11-12 INSECTICIDE METHODS USING PIRIDINE COMPOUNDS

Country Status (4)

Country Link
AR (1) AR079425A1 (en)
TW (1) TW201121422A (en)
UY (1) UY33031A (en)
WO (1) WO2011057942A1 (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8937177B2 (en) 2010-03-23 2015-01-20 Basf Se Pyridazine compounds for controlling invertebrate pests
JP2013522356A (en) 2010-03-23 2013-06-13 ビーエーエスエフ ソシエタス・ヨーロピア Pyridazine compounds for controlling invertebrate pests
CN103097376A (en) 2010-09-13 2013-05-08 巴斯夫欧洲公司 Pyridine compounds for controlling invertebrate pests ii
WO2012034961A1 (en) 2010-09-13 2012-03-22 Basf Se Pyridine compounds for controlling invertebrate pests i
WO2012150550A1 (en) * 2011-05-04 2012-11-08 Basf Se Novel pesticidal amino pyranone compounds
CA2978823C (en) 2014-12-29 2023-10-10 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Small molecule inhibitors of lactate dehydrogenase and methods of use thereof
EP3133065A1 (en) 2015-08-21 2017-02-22 Merck Patent GmbH Compounds for optically active devices
CN107840825B (en) * 2016-09-21 2019-11-05 湖南化工研究院有限公司 Hepta-fluoroiso-propyl quinolines and the preparation method and application thereof
EP3363793A1 (en) 2017-02-15 2018-08-22 Merck Patent GmbH Hydrophobic compounds for optically active devices
EP3363786A1 (en) 2017-02-15 2018-08-22 Merck Patent GmbH Compounds for optically active devices
CN111303163B (en) * 2020-05-14 2020-08-11 北京鑫开元医药科技有限公司 Compound with JAK kinase inhibitory activity, preparation method, composition and application
WO2021233800A1 (en) 2020-05-20 2021-11-25 Merck Patent Gmbh Azacoumarin and azathiocoumarin derivatives for use in optically active devices

Family Cites Families (73)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3060084A (en) 1961-06-09 1962-10-23 Du Pont Improved homogeneous, readily dispersed, pesticidal concentrate
US3299566A (en) 1964-06-01 1967-01-24 Olin Mathieson Water soluble film containing agricultural chemicals
US4144050A (en) 1969-02-05 1979-03-13 Hoechst Aktiengesellschaft Micro granules for pesticides and process for their manufacture
US3920442A (en) 1972-09-18 1975-11-18 Du Pont Water-dispersible pesticide aggregates
US4172714A (en) 1976-12-20 1979-10-30 E. I. Du Pont De Nemours And Company Dry compactible, swellable herbicidal compositions and pellets produced therefrom
GB2095558B (en) 1981-03-30 1984-10-24 Avon Packers Ltd Formulation of agricultural chemicals
BR8404834A (en) 1983-09-26 1985-08-13 Agrigenetics Res Ass METHOD TO GENETICALLY MODIFY A PLANT CELL
US5304732A (en) 1984-03-06 1994-04-19 Mgi Pharma, Inc. Herbicide resistance in plants
BR8600161A (en) 1985-01-18 1986-09-23 Plant Genetic Systems Nv CHEMICAL GENE, HYBRID, INTERMEDIATE PLASMIDIO VECTORS, PROCESS TO CONTROL INSECTS IN AGRICULTURE OR HORTICULTURE, INSECTICIDE COMPOSITION, PROCESS TO TRANSFORM PLANT CELLS TO EXPRESS A PLANTINIDE TOXIN, PRODUCED BY CULTURES, UNITED BY BACILLA
EP0242236B2 (en) 1986-03-11 1996-08-21 Plant Genetic Systems N.V. Plant cells resistant to glutamine synthetase inhibitors, made by genetic engineering
US5013659A (en) 1987-07-27 1991-05-07 E. I. Du Pont De Nemours And Company Nucleic acid fragment encoding herbicide resistant plant acetolactate synthase
IL83348A (en) 1986-08-26 1995-12-08 Du Pont Nucleic acid fragment encoding herbicide resistant plant acetolactate synthase
FR2629098B1 (en) 1988-03-23 1990-08-10 Rhone Poulenc Agrochimie CHEMICAL GENE OF HERBICIDE RESISTANCE
KR900003088B1 (en) 1988-03-26 1990-05-07 재단법인 한국화학연구소 5-hydroxy prazole derivatives
US5180587A (en) 1988-06-28 1993-01-19 E. I. Du Pont De Nemours And Company Tablet formulations of pesticides
CA2005658A1 (en) 1988-12-19 1990-06-19 Eliahu Zlotkin Insecticidal toxins, genes encoding these toxins, antibodies binding to them and transgenic plant cells and plants expressing these toxins
DK0392225T3 (en) 1989-03-24 2003-09-22 Syngenta Participations Ag Disease resistant transgenic plants
ATE208560T1 (en) 1989-08-30 2001-11-15 Kynoch Agrochemicals Proprieta PRODUCTION OF A DOSAGE AGENT
DK0427529T3 (en) 1989-11-07 1995-06-26 Pioneer Hi Bred Int Larval killing lactins and plant insect resistance based thereon
EP0519937B1 (en) 1990-03-12 1994-12-28 E.I. Du Pont De Nemours And Company Water-dispersible or water-soluble pesticide granules from heat-activated binders
EP0472722B1 (en) 1990-03-16 2003-05-21 Calgene LLC Dnas encoding plant desaturases and their uses
JP3325022B2 (en) 1990-06-18 2002-09-17 モンサント カンパニー Increased starch content in plants
ES2173077T3 (en) 1990-06-25 2002-10-16 Monsanto Technology Llc PLANTS THAT TOLERATE GLYPHOSATE.
ES2091878T3 (en) 1990-10-11 1996-11-16 Sumitomo Chemical Co PESTICIDE COMPOSITION.
SE467358B (en) 1990-12-21 1992-07-06 Amylogene Hb GENETIC CHANGE OF POTATISE BEFORE EDUCATION OF AMYLOPECT TYPE STARCH
DE4104782B4 (en) 1991-02-13 2006-05-11 Bayer Cropscience Gmbh Novel plasmids containing DNA sequences that cause changes in carbohydrate concentration and carbohydrate composition in plants, as well as plants and plant cells containing these plasmids
EP0533882B1 (en) * 1991-04-03 2001-02-07 Korea Research Institute Of Chemical Technology 2-quinolinone derivatives, methods for preparing the same and fungicides and insecticides including them
UA48104C2 (en) 1991-10-04 2002-08-15 Новартіс Аг Dna fragment including sequence that codes an insecticide protein with optimization for corn, dna fragment providing directed preferable for the stem core expression of the structural gene of the plant related to it, dna fragment providing specific for the pollen expression of related to it structural gene in the plant, recombinant dna molecule, method for obtaining a coding sequence of the insecticide protein optimized for corn, method of corn plants protection at least against one pest insect
KR0124946B1 (en) * 1993-06-22 1997-12-08 강박광 Quinolone derivatives
DE4322211A1 (en) 1993-07-03 1995-01-12 Basf Ag Aqueous, multi-phase, stable ready-to-use formulation for crop protection agents and processes for their preparation
US5530195A (en) 1994-06-10 1996-06-25 Ciba-Geigy Corporation Bacillus thuringiensis gene encoding a toxin active against insects
DE19613334A1 (en) 1996-04-03 1997-10-09 Bayer Ag Means for controlling parasitic insects and mites on humans
US5773704A (en) 1996-04-29 1998-06-30 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Herbicide resistant rice
AU3596697A (en) 1996-07-17 1998-02-09 Michigan State University Imidazolinone herbicide resistant sugar beet plants
US5773702A (en) 1996-07-17 1998-06-30 Board Of Trustees Operating Michigan State University Imidazolinone herbicide resistant sugar beet plants
US6348643B1 (en) 1998-10-29 2002-02-19 American Cyanamid Company DNA sequences encoding the arabidopsis acetohydroxy-acid synthase small subunit and methods of use
MX233208B (en) 2000-04-28 2005-12-20 Basf Ag Use of the maize x112 mutant ahas 2 gene and imidazolinone herbicides for selection of transgenic monocots, maize, rice and wheat plants resistant to the imidazolinone herbicides.
ES2243543T3 (en) 2000-08-25 2005-12-01 Syngenta Participations Ag HYBRIDS OF BACILLUS THURIGIENSIS CRYSTAL PROTEINS.
TWI223979B (en) 2001-05-09 2004-11-21 Sumitomo Chemical Co Malononitrile compounds and pesticide composition containing the same as well as pest controlling method
AR034760A1 (en) 2001-08-09 2004-03-17 Northwest Plant Breeding Company WHEAT PLANTS THAT HAVE INCREASED RESISTANCE TO IMIDAZOLINONA HERBICIDES
US7521599B2 (en) 2001-08-09 2009-04-21 University Of Saskatchewan Wheat plants having increased resistance to imidazolinone herbicides
BRPI0211809B1 (en) 2001-08-09 2019-04-24 University Of Saskatchewan METHOD FOR THE CONTROL OF WEED HERBS IN THE NEIGHBORHOODS OF A WHEAT OR TRITICALE PLANT, METHOD FOR MODIFYING THE TOLERANCE OF A WHEAT OR TRITICALE PLANT AND AN IMMEDAZOLINET PRODUCT RESULTING PLANT A HERBICIDE OF IMIDAZOLINONE
US7230167B2 (en) 2001-08-31 2007-06-12 Syngenta Participations Ag Modified Cry3A toxins and nucleic acid sequences coding therefor
WO2003052073A2 (en) 2001-12-17 2003-06-26 Syngenta Participations Ag Novel corn event
DE10216737A1 (en) 2002-04-16 2003-10-30 Bayer Ag Control of parasites in animals
WO2004016073A2 (en) 2002-07-10 2004-02-26 The Department Of Agriculture, Western Australia Wheat plants having increased resistance to imidazolinone herbicides
ES2276090T3 (en) 2002-07-17 2007-06-16 Sumitomo Chemical Company, Limited MALONITRILE COMPOUNDS AND THEIR EMPLOYMENT AS PESTICIDES.
MXPA05012733A (en) 2003-05-28 2006-05-17 Basf Ag Wheat plants having increased tolerance to imidazolinone herbicides.
BRPI0413917B1 (en) 2003-08-29 2018-09-25 Instituto Nacional De Tech Agropecuaria non-transgenic mutagenized rice ahas nucleic acid, isolated ahas polypeptide, and weed control method within the vicinity of a rice plant
ATE530517T1 (en) 2003-12-26 2011-11-15 Sumitomo Chemical Co NITRILE COMPOUND AND ITS USE IN PEST CONTROL
RU2347779C2 (en) 2004-01-16 2009-02-27 Сумитомо Кемикал Компани, Лимитед Malononitrile compound as pesticide
RU2362769C2 (en) 2004-01-16 2009-07-27 Сумитомо Кемикал Компани, Лимитед Malononitryl derivatives and their application
EA011764B1 (en) 2004-03-05 2009-06-30 Ниссан Кемикал Индастриз, Лтд. Isoxazoline-substituted benzamide compound and pesticide
JP2006131529A (en) 2004-11-05 2006-05-25 Sumitomo Chemical Co Ltd Pest control composition
WO2007026965A1 (en) 2005-09-02 2007-03-08 Nissan Chemical Industries, Ltd. Isoxazoline-substituted benzamide compound and harmful organism-controlling agent
CA2623202C (en) 2005-10-14 2014-09-16 Sumitomo Chemical Company, Limited Hydrazide compound and pesticidal use of the same
WO2007060839A1 (en) 2005-11-22 2007-05-31 Sumitomo Chemical Company, Limited Organic sulfur compounds and use thereof as arthropodicides
TWI412322B (en) 2005-12-30 2013-10-21 Du Pont Isoxazolines for controlling invertebrate pests
DE102006015197A1 (en) 2006-03-06 2007-09-13 Bayer Cropscience Ag Active ingredient combination with insecticidal properties
DE102006015467A1 (en) 2006-03-31 2007-10-04 Bayer Cropscience Ag New cyclic enamine ketone derivatives useful for controlling pests, especially insects
GB0614471D0 (en) 2006-07-20 2006-08-30 Syngenta Ltd Herbicidal Compounds
DE102006039255A1 (en) * 2006-08-17 2008-02-21 Bayer Cropscience Ag Insecticidal heterocyclic carboxylic acid derivatives
WO2008066153A1 (en) 2006-11-30 2008-06-05 Meiji Seika Kaisha, Ltd. Pest control agent
GB0624760D0 (en) 2006-12-12 2007-01-17 Syngenta Ltd Herbicidal compounds
JP5449669B2 (en) 2006-12-14 2014-03-19 石原産業株式会社 Pest control composition
JP2009001541A (en) 2006-12-15 2009-01-08 Ishihara Sangyo Kaisha Ltd Method for producing anthranilamide compound using new pyrazole compound as intermediate
CN101626687B (en) 2007-03-08 2014-07-02 明治制果药业株式会社 Pest control composition
JP2008115155A (en) 2007-04-06 2008-05-22 Nippon Soda Co Ltd Pest-controlling agent composition and pest-controlling method
WO2009051956A2 (en) 2007-10-16 2009-04-23 E. I. Du Pont De Nemours And Company Pyrazole-substituted isoxazoline insecticides
GB0800855D0 (en) 2008-01-17 2008-02-27 Syngenta Ltd Herbicidal compounds
GB0800856D0 (en) 2008-01-17 2008-02-27 Syngenta Ltd Herbicidal compounds
TW201444787A (en) 2008-04-09 2014-12-01 Du Pont Method for preparing 3-trifluoromethyl chalcones
KR20110082058A (en) * 2008-10-29 2011-07-15 바스프 에스이 Substituted pyridines having a herbicidal effect

Also Published As

Publication number Publication date
TW201121422A (en) 2011-07-01
UY33031A (en) 2011-05-31
WO2011057942A1 (en) 2011-05-19

Similar Documents

Publication Publication Date Title
AR079425A1 (en) INSECTICIDE METHODS USING PIRIDINE COMPOUNDS
AR074070A1 (en) PIRIDINES REPLACED WITH HERBICITY ACTION
AR074788A1 (en) HETEROCICLICAL COMPOUNDS WITH HERBICIDE EFFECT
AR079401A1 (en) REPLACED CYANOBUTIRATES WITH HERBICITY ACTION
AR082087A1 (en) PIRIDAZINAS REPLACED THAT HAVE HERBICITY ACTION
AR080781A1 (en) PIRIDAZINAS REPLACED THAT HAVE HERBICITY ACTION
AR058203A1 (en) INSECTICIDE METHODS THAT USE DERIVATIVES OF 3- AMINO -1,2- BENCISOTIAZOL
AR079524A1 (en) CYANOBUTIRATES REPLACED WITH HERBICIDE ACTION, PROCESS TO PREPARE THEM, HERBICIDE COMPOSITION CONTAINING THEM AND METHOD TO CONTROL INDENATED VEGETATION
RU2004129580A (en) O-CYCLOPROPYL CARBOXANANIDES AND THEIR APPLICATION AS FUNGICIDES
PE20091189A1 (en) COMBINATIONS OF ACTIVE PRINCIPLES WITH INSECTICIDE AND ACARICIDAL PROPERTIES
RU2011129408A (en) HETEROCYCLIC NITROGEN-CONTAINING OR OXYGEN-CONTAINING COMPOUNDS WITH INSECTICIDAL ACTIVITY FORMED FROM DIALDEHYDE AND THEIR PRODUCTION AND APPLICATION
PE20061295A1 (en) ACETYLENE DERIVATIVES
RU2015131110A (en) 1- (SUBSTITUTED BENZOYL) -5-fluoro-4-imino-3-methyl-3,4-dihydro-pyrimidine-2 (1H) -one derivatives
UY33239A (en) DIHYDROFURAN DERIVATIVES AS INSECTICIDE COMPOUNDS
AR080782A1 (en) PIRIDOTIACINAS THAT HAVE HERBICIDE ACTION, COMPOSITION THAT UNDERSTANDS THEM AND A METHOD TO CONTROL THE INDEGATED VEGETATION
UY29659A1 (en) N-TIO ANTRANILAMIDE COMPOUNDS AND THEIR USES AS PESTICIDES
RU2014110049A (en) 5-fluoro-4-imino-3- (substituted) -3,4-dihydro-pyrimidine-2 (1H) OH derivatives
AR067512A1 (en) DERIVATIVES OF TROPANO, PREPARATION PROCESSES, COMPOSITIONS AND USES
AR065199A1 (en) PESTICIDE BLENDS
AR068121A1 (en) MULTICICLICAL COMPOUNDS TO TREAT NEURODEGENERATIVE DISEASES
AR076986A1 (en) PIRAZINAS REPLACED WITH HERBICITY ACTION AND PROCEDURE TO PREPARE SUCH COMPOUNDS
AR080160A1 (en) CYANOBUTIRATES REPLACED WITH HERBICIDE ACTION, PROCESS TO PREPARE THEM, HERBICIDE COMPOSITION CONTAINING THEM AND METHOD TO CONTROL INDENATED VEGETATION
AR086466A1 (en) COMBINATIONS OF ACTIVE COMPOUNDS THAT INCLUDE A DERIVATIVE OF (UNCLE) CARBOXAMIDE AND AN INSECTICIATED OR ACARICIDE OR NEMATICIDE ACTIVE COMPOUND
AR085005A1 (en) REPLACED PYRIDINS THAT HAVE HERBICITY ACTION
AR081527A1 (en) REPLACED PYRIDINS THAT HAVE HERBICITY ACTION

Legal Events

Date Code Title Description
FB Suspension of granting procedure