AR072135A1 - Formas de dosificacion de fenofibrato - Google Patents
Formas de dosificacion de fenofibratoInfo
- Publication number
- AR072135A1 AR072135A1 ARP090101116A ARP090101116A AR072135A1 AR 072135 A1 AR072135 A1 AR 072135A1 AR P090101116 A ARP090101116 A AR P090101116A AR P090101116 A ARP090101116 A AR P090101116A AR 072135 A1 AR072135 A1 AR 072135A1
- Authority
- AR
- Argentina
- Prior art keywords
- fenofibrate
- particles
- dosage forms
- physiological conditions
- dosage form
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/265—Esters, e.g. nitroglycerine, selenocyanates of carbonic, thiocarbonic, or thiocarboxylic acids, e.g. thioacetic acid, xanthogenic acid, trithiocarbonic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Emergency Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Obesity (AREA)
- Physiology (AREA)
- Hematology (AREA)
- Nutrition Science (AREA)
- Endocrinology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Metodos in vitro para evaluar la efectividad in vivo de formas de dosis del fibrato, tal como fenofibrato. Los metodos utilizan medios representativos en condiciones fisiologicas humanas in vivo. Reivindicacion 1: Una forma de dosificacion de fenofibrato caracterizada porque comprende: part¡culas que consisten en fenofibrato; y al menos un estabilizador de superficie adsorbido en la superficie de las part¡culas, en donde despues de la reconstitucion en un medio acuoso de relevancia biologica que imita las condiciones fisiologicas humanas, las part¡culas de fenofibrato se caracterizan por una distribucion de tamano de part¡cula estable que tiene un tamano de part¡cula promedio efectivo de menos de 2000 nm. Reivindicacion 25: La forma de dosificacion de la reivindicacion 1 caracterizada porque adem s comprende uno o m s agentes activos seleccionados del grupo que consiste en agentes antihiperglucemicos, estatinas, inhibidores de HMGCoA reductasa y antihipertensivos.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US12/058,497 US20080241070A1 (en) | 2000-09-21 | 2008-03-28 | Fenofibrate dosage forms |
Publications (1)
Publication Number | Publication Date |
---|---|
AR072135A1 true AR072135A1 (es) | 2010-08-11 |
Family
ID=40846436
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP090101116A AR072135A1 (es) | 2008-03-28 | 2009-03-27 | Formas de dosificacion de fenofibrato |
Country Status (7)
Country | Link |
---|---|
US (1) | US20080241070A1 (es) |
EP (1) | EP2271316A2 (es) |
JP (1) | JP2011516421A (es) |
AR (1) | AR072135A1 (es) |
CA (1) | CA2719811A1 (es) |
TW (1) | TW201006466A (es) |
WO (1) | WO2009120919A2 (es) |
Families Citing this family (16)
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US7276249B2 (en) * | 2002-05-24 | 2007-10-02 | Elan Pharma International, Ltd. | Nanoparticulate fibrate formulations |
US20090202649A1 (en) * | 2008-02-06 | 2009-08-13 | Subhash Gore | Fenofibrate formulations |
CA2788777C (en) | 2009-02-23 | 2015-02-17 | NanoRx, Inc. | Policosanol nanoparticles |
US9034383B2 (en) | 2010-08-23 | 2015-05-19 | NanoRx, Inc. | Policosanol nanoparticles |
US9232790B2 (en) * | 2011-08-02 | 2016-01-12 | Kimberly-Clark Worldwide, Inc. | Antimicrobial cleansing compositions |
US20140255480A1 (en) * | 2011-09-07 | 2014-09-11 | Ethypharm | Pharmaceutical formulation of nanonized fenofibrate |
US9439860B2 (en) | 2012-06-25 | 2016-09-13 | Mylan, Inc. | Fenofibrate formulation |
EP2863890A4 (en) * | 2012-06-25 | 2015-12-09 | Mylan Inc | FORMULATION OF FENOFIBRATE |
US8722083B2 (en) | 2012-06-25 | 2014-05-13 | Mylan, Inc. | Fenofibrate formulation |
WO2014091318A1 (en) | 2012-12-11 | 2014-06-19 | Lupin Atlantis Holdings, S.A. | Reduced dose pharmaceutical compositions of fenofibrate |
WO2015167547A1 (en) | 2014-04-30 | 2015-11-05 | Kimberly-Clark Worldwide, Inc. | Methods of reducing signs of skin aging |
MX2016013135A (es) | 2014-04-30 | 2017-01-20 | Kimberly Clark Co | Composiciones y metodos para reducir el estres oxidativo. |
US10646430B2 (en) | 2014-04-30 | 2020-05-12 | Kimberly-Clark Worldwide, Inc. | Topical compositions for stimulating adipogenesis and lipogenesis to reduce the signs of skin aging |
AU2014392629B2 (en) | 2014-04-30 | 2021-04-01 | Kimberly-Clark Worldwide, Inc. | Use of Undaria extract to reduce signs of skin aging |
EP3928772B1 (en) | 2020-06-26 | 2024-06-19 | Algiax Pharmaceuticals GmbH | Nanoparticulate composition |
WO2022183281A1 (en) * | 2021-03-03 | 2022-09-09 | Mcmaster Christopher R | Compounds and treatments for muscular dystrophy |
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ATE357216T1 (de) * | 2001-02-22 | 2007-04-15 | Jagotec Ag | Fibrat-statin kombinationen mit verminderten von der nahrungsaufnahme abhängigen auswirkungen |
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-
2008
- 2008-03-28 US US12/058,497 patent/US20080241070A1/en not_active Abandoned
-
2009
- 2009-03-25 TW TW098109709A patent/TW201006466A/zh unknown
- 2009-03-27 CA CA2719811A patent/CA2719811A1/en not_active Abandoned
- 2009-03-27 EP EP09726084A patent/EP2271316A2/en not_active Withdrawn
- 2009-03-27 AR ARP090101116A patent/AR072135A1/es unknown
- 2009-03-27 JP JP2011502085A patent/JP2011516421A/ja active Pending
- 2009-03-27 WO PCT/US2009/038490 patent/WO2009120919A2/en active Application Filing
Also Published As
Publication number | Publication date |
---|---|
TW201006466A (en) | 2010-02-16 |
CA2719811A1 (en) | 2009-10-01 |
JP2011516421A (ja) | 2011-05-26 |
US20080241070A1 (en) | 2008-10-02 |
WO2009120919A3 (en) | 2010-11-04 |
WO2009120919A2 (en) | 2009-10-01 |
EP2271316A2 (en) | 2011-01-12 |
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