AR066232A1 - Combinacion de antagonista del receptor de progesterona con un inhibidor de la aromatasa para usar en enfermedades mediadas por brca (genes supresores de tumores) - Google Patents
Combinacion de antagonista del receptor de progesterona con un inhibidor de la aromatasa para usar en enfermedades mediadas por brca (genes supresores de tumores)Info
- Publication number
- AR066232A1 AR066232A1 ARP080101668A ARP080101668A AR066232A1 AR 066232 A1 AR066232 A1 AR 066232A1 AR P080101668 A ARP080101668 A AR P080101668A AR P080101668 A ARP080101668 A AR P080101668A AR 066232 A1 AR066232 A1 AR 066232A1
- Authority
- AR
- Argentina
- Prior art keywords
- combination
- progesterone
- diseases
- brca
- 11beta
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Combinacion del antagonista del receptor de progesterona 11beta-(4-acetilfenil)-17beta-hidroxi-17alfa-(1,1,2,2,2-pentafluoroetil)-estra-4,9- dien-3-ona, o un derivado o un análogo de éste aceptable para uso farmacéutico, con al menos un inhibidor dela aromatasa, y uso de dicha combinacion para la profilaxis y el tratamiento de enfermedades mediadas por BRCA1 o BRCA2 (genes supresores de tumores 1 o 2). Los inhibidores de la aromatasa que pueden combinarse con el compuesto 11beta-(4-acetilfenil)-17beta-hidroxi-17alfa-(1,1,2,2,2-pentafluoroetil)-estra-4,9-dien-3-ona, son, por ejemplo, aminoglutetimida, fadrozol, anastrozol, letrozol, vorozol, formestano, exemestano y atamestano. Reivindicacion 8: Una combinacion farmacéuticade acuerdo con las reivindicaciones 1 a 7, caracterizada porque la combinacion comprende el antagonista del receptor de progesterona 11beta-(4-acetil-fenil)-17beta-hidroxi-17alfa-(1,1,2,2,2-pentafluoroetil)-estra-4,9-dien-3-ona, un inhibidor de laaromatasa y-un agente con actividad farmacologica. Reivindicacion 9: Una combinacion farmacéutica de acuerdo con la reivindicacion 8, caracterizada porque el agente con actividad farmacologica es un agente citotoxico.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP07090081 | 2007-04-23 | ||
| US91437307P | 2007-04-27 | 2007-04-27 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR066232A1 true AR066232A1 (es) | 2009-08-05 |
Family
ID=39872870
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP080101668A AR066232A1 (es) | 2007-04-23 | 2008-04-22 | Combinacion de antagonista del receptor de progesterona con un inhibidor de la aromatasa para usar en enfermedades mediadas por brca (genes supresores de tumores) |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20080261929A1 (es) |
| EP (1) | EP2136842A1 (es) |
| JP (1) | JP2010524994A (es) |
| AR (1) | AR066232A1 (es) |
| CA (1) | CA2684806A1 (es) |
| CL (1) | CL2008001150A1 (es) |
| PA (2) | PA8777401A1 (es) |
| PE (1) | PE20090233A1 (es) |
| TW (1) | TW200902028A (es) |
| UY (1) | UY31043A1 (es) |
| WO (1) | WO2008128784A1 (es) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9603856B2 (en) | 2013-11-03 | 2017-03-28 | Flamina Holding Ag | Pharmaceutical composition or group of compositions for inhibiting autocrine HCG production in adult human cells |
| TWI639430B (zh) * | 2016-08-27 | 2018-11-01 | 中國醫藥大學 | 醫藥組合物用於製備治療胃癌藥物的用途 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6476079B1 (en) * | 1999-12-23 | 2002-11-05 | Leiras Oy | Devices for the delivery of drugs having antiprogestinic properties |
| EE05259B1 (et) * | 2000-10-18 | 2010-02-15 | Schering Aktiengesellschaft | Antiprogestiinide kasutamine hormoons?ltuvate haiguste proflaktikaks ja raviks |
| US20040242551A1 (en) * | 2003-05-28 | 2004-12-02 | Schering Ag | Composition comprising antiprogestins and pure antiestrogens for prophylaxis and treatment of hormone-dependent diseases |
-
2008
- 2008-04-18 US US12/105,356 patent/US20080261929A1/en not_active Abandoned
- 2008-04-21 CA CA002684806A patent/CA2684806A1/en not_active Abandoned
- 2008-04-21 JP JP2010504546A patent/JP2010524994A/ja not_active Withdrawn
- 2008-04-21 EP EP08735383A patent/EP2136842A1/en not_active Withdrawn
- 2008-04-21 WO PCT/EP2008/003324 patent/WO2008128784A1/en active Application Filing
- 2008-04-22 PA PA20088777401A patent/PA8777401A1/es unknown
- 2008-04-22 PA PA20088777501A patent/PA8777501A1/es unknown
- 2008-04-22 UY UY31043A patent/UY31043A1/es not_active Application Discontinuation
- 2008-04-22 TW TW097114709A patent/TW200902028A/zh unknown
- 2008-04-22 CL CL2008001150A patent/CL2008001150A1/es unknown
- 2008-04-22 AR ARP080101668A patent/AR066232A1/es unknown
- 2008-04-22 PE PE2008000688A patent/PE20090233A1/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| PA8777501A1 (es) | 2008-11-19 |
| CA2684806A1 (en) | 2008-10-30 |
| US20080261929A1 (en) | 2008-10-23 |
| UY31043A1 (es) | 2008-11-28 |
| EP2136842A1 (en) | 2009-12-30 |
| JP2010524994A (ja) | 2010-07-22 |
| TW200902028A (en) | 2009-01-16 |
| PE20090233A1 (es) | 2009-04-08 |
| WO2008128784A1 (en) | 2008-10-30 |
| PA8777401A1 (es) | 2008-11-19 |
| CL2008001150A1 (es) | 2008-11-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |