AR055310A1 - Arreglos de microproyecciones con mejor biocompatibilidad - Google Patents

Arreglos de microproyecciones con mejor biocompatibilidad

Info

Publication number
AR055310A1
AR055310A1 ARP060100553A ARP060100553A AR055310A1 AR 055310 A1 AR055310 A1 AR 055310A1 AR P060100553 A ARP060100553 A AR P060100553A AR P060100553 A ARP060100553 A AR P060100553A AR 055310 A1 AR055310 A1 AR 055310A1
Authority
AR
Argentina
Prior art keywords
microprojection
arrangements
better biocompatibility
microns
biocompatibility
Prior art date
Application number
ARP060100553A
Other languages
English (en)
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corp filed Critical Alza Corp
Publication of AR055310A1 publication Critical patent/AR055310A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0021—Intradermal administration, e.g. through microneedle arrays, needleless injectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0046—Solid microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0053—Methods for producing microneedles

Landscapes

  • Health & Medical Sciences (AREA)
  • Dermatology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Anesthesiology (AREA)
  • Medical Informatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

Un componente de administracion transdérmica que tiene una pluralidad de microproyecciones adaptadas para perforar el estrato corneo de un sujeto, cada una de las cuales tiene una longitud de menos de 145 micrones. En una forma de realizacion que se prefiere, cada microproyeccion tiene una longitud en el rango de aproximadamente 50-145 micones.
ARP060100553A 2005-02-16 2006-02-15 Arreglos de microproyecciones con mejor biocompatibilidad AR055310A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US65367505P 2005-02-16 2005-02-16

Publications (1)

Publication Number Publication Date
AR055310A1 true AR055310A1 (es) 2007-08-15

Family

ID=36448927

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP060100553A AR055310A1 (es) 2005-02-16 2006-02-15 Arreglos de microproyecciones con mejor biocompatibilidad

Country Status (9)

Country Link
US (1) US20060204562A1 (es)
EP (1) EP1848492A1 (es)
JP (1) JP2008529750A (es)
CN (1) CN101119764A (es)
AR (1) AR055310A1 (es)
AU (1) AU2006213994A1 (es)
CA (1) CA2596120A1 (es)
TW (1) TW200640519A (es)
WO (1) WO2006089285A1 (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR008242A1 (es) * 1996-06-18 1999-12-29 Alza Corp Dispositivo para atravesar el estrato corneo de una superficie corporal
CN100571643C (zh) 2003-10-31 2009-12-23 阿尔扎公司 用于微凸起阵列的自驱动施加器
EP1853231A2 (en) * 2005-02-16 2007-11-14 Alza Corporation Apparatus and method for transdermal delivery of erythropoetin-based agents
WO2007033015A1 (en) * 2005-09-12 2007-03-22 Alza Corporation Coatable transdermal delivery microprojection assembly
CA2680690A1 (en) * 2006-03-15 2007-09-20 Alza Corporation Apparatus and method for transdermal delivery of parathyroid hormone agents to prevent or treat osteopenia
WO2007127815A2 (en) * 2006-04-25 2007-11-08 Alza Corporation Microprojection array application with multilayered microprojection member for high drug loading
US20070293816A1 (en) * 2006-04-25 2007-12-20 Alza Corporation Microprojection Array Application with Grouped Microprojections for High Drug Loading
US20150038897A1 (en) 2013-07-30 2015-02-05 Zosano Pharma, Inc. Low-Profile Microneedle Patch Applicator

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3964482A (en) * 1971-05-17 1976-06-22 Alza Corporation Drug delivery device
BE795384A (fr) * 1972-02-14 1973-08-13 Ici Ltd Pansements
FR2232331B1 (es) * 1973-06-06 1978-03-24 Guerin A Ets
US5080646A (en) * 1988-10-03 1992-01-14 Alza Corporation Membrane for electrotransport transdermal drug delivery
US5147296A (en) * 1988-10-03 1992-09-15 Alza Corporation Membrane for electrotransport transdermal drug delivery
US5169382A (en) * 1988-10-03 1992-12-08 Alza Corporation Membrane for electrotransport transdermal drug delivery
EP0429842B1 (en) * 1989-10-27 1996-08-28 Korea Research Institute Of Chemical Technology Device for the transdermal administration of protein or peptide drug
CA2149836C (en) * 1994-05-23 1999-07-06 Sang Bae Choi Perforating device for dermal administration
JP2551742B2 (ja) * 1994-05-23 1996-11-06 三星電機株式会社 医薬品投与用皮膚傷形成装置
AU5740496A (en) * 1995-05-22 1996-12-11 General Hospital Corporation, The Micromechanical device and method for enhancing delivery of compounds through the skin
AR008242A1 (es) * 1996-06-18 1999-12-29 Alza Corp Dispositivo para atravesar el estrato corneo de una superficie corporal
KR100572539B1 (ko) * 1997-12-11 2006-04-24 알자 코포레이션 경피성 작용제 유동률을 증진시키기 위한 장치
CN1206004C (zh) * 1997-12-11 2005-06-15 阿尔扎有限公司 增强透皮物剂流量的装置
US6623457B1 (en) * 1999-09-22 2003-09-23 Becton, Dickinson And Company Method and apparatus for the transdermal administration of a substance
EP2085109A3 (en) * 2000-10-26 2009-09-02 Alza Corporation Transdermal drug delivery devices having coated microprotrusions
US6767341B2 (en) * 2001-06-13 2004-07-27 Abbott Laboratories Microneedles for minimally invasive drug delivery
TW200409657A (en) * 2002-08-08 2004-06-16 Alza Corp Transdermal vaccine delivery device having coated microprotrusions
US20040106904A1 (en) * 2002-10-07 2004-06-03 Gonnelli Robert R. Microneedle array patch
PE20050288A1 (es) * 2003-07-02 2005-04-29 Alza Corp Metodo y parche de inmunizacion por disposicion de microproyeccion

Also Published As

Publication number Publication date
EP1848492A1 (en) 2007-10-31
CA2596120A1 (en) 2006-08-24
WO2006089285A1 (en) 2006-08-24
US20060204562A1 (en) 2006-09-14
JP2008529750A (ja) 2008-08-07
TW200640519A (en) 2006-12-01
CN101119764A (zh) 2008-02-06
AU2006213994A1 (en) 2006-08-24

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