AR053135A1 - Compuestos betamimeticos eficaces a largo plazo para el tratamiento de enfermedades respiratorias - Google Patents
Compuestos betamimeticos eficaces a largo plazo para el tratamiento de enfermedades respiratoriasInfo
- Publication number
- AR053135A1 AR053135A1 ARP060100567A ARP060100567A AR053135A1 AR 053135 A1 AR053135 A1 AR 053135A1 AR P060100567 A ARP060100567 A AR P060100567A AR P060100567 A ARP060100567 A AR P060100567A AR 053135 A1 AR053135 A1 AR 053135A1
- Authority
- AR
- Argentina
- Prior art keywords
- alkyl
- cr4r5
- compounds
- treatment
- respiratory diseases
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Pulmonology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Formulacion farmacéutica, así como a su uso como fármaco, especialmente como fármaco par el tratamiento de enfermedades respiratorias. Reivindicacion 1: Compuestos de formula (1) en los que n significa 1, 2, 3 o 4; A un grupo divalente seleccionado del grupo formado por -O-, -CR4R5-, -NR6-, -S-, -CR4R5-O-, -CR4R5-NR6-, -CH=CH- o -CH2-CH2-; R1 -alquilo C1-6; R2 y R3, iguales o diferentes, H, alquilo C1-6, alquenilo C2-6, alquinilo C2-6, cicloalquilo C3-6, haloalquilo C1-6, -O-haloalquilo C1-6, halogeno, OH, CN, NO2, O-alquilo C1-6, alquilo C2-6-OH, NH2, NH-alquilo C1-6, N(alquilo C1-6)2, NHCO-alquilo C1-6, NHSO2-alquilo C1-6, S-alquilo C1-6, SO-alquilo C1-6, SO2-alquilo C1-6, SO2NH2, SO2NH-alquilo C1-6, SO2N(alquilo C1-6)2, CONH2, CONH- alquilo C1-6, CON(alquilo C1-6)2, -CO-alquilo C1-6, COOH o COO-alquilo C1-4, o R2 y R3 significan juntos un grupo divalente seleccionado de -O-CR4R5-O-, -O-CR4R5-NR6- o -CH=CH-CH=CH-; R4 H o alquilo C1-6, R5 H o alquilo C1-6, R6 H o alquilo C1-6, dado el caso en forma de los enantiomeros individuales, mezclas de los enantiomeros individuales o racematos, dado el caso en forma de sus sales de adicion de ácidos farmacologicamente inocuos, así como dado el caso en forma de sus solvatos y/o hidratos.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102005007654A DE102005007654A1 (de) | 2005-02-19 | 2005-02-19 | Neue langwirksame Betamimetika zur Behandlung von Atemwegserkrankungen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR053135A1 true AR053135A1 (es) | 2007-04-25 |
Family
ID=36607505
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP060100567A AR053135A1 (es) | 2005-02-19 | 2006-02-17 | Compuestos betamimeticos eficaces a largo plazo para el tratamiento de enfermedades respiratorias |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US7423036B2 (es) |
| EP (1) | EP1853596B1 (es) |
| JP (1) | JP5140434B2 (es) |
| AR (1) | AR053135A1 (es) |
| AT (1) | ATE496913T1 (es) |
| CA (1) | CA2598355A1 (es) |
| DE (2) | DE102005007654A1 (es) |
| ES (1) | ES2357620T3 (es) |
| TW (1) | TW200640911A (es) |
| WO (1) | WO2006087315A1 (es) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7056916B2 (en) * | 2002-11-15 | 2006-06-06 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Medicaments for the treatment of chronic obstructive pulmonary disease |
| US20050272726A1 (en) * | 2004-04-22 | 2005-12-08 | Boehringer Ingelheim International Gmbh | Novel medicaments for the treatment of respiratory diseases |
| US7220742B2 (en) * | 2004-05-14 | 2007-05-22 | Boehringer Ingelheim International Gmbh | Enantiomerically pure beta agonists, process for the manufacture thereof and use thereof as medicaments |
| US20050255050A1 (en) * | 2004-05-14 | 2005-11-17 | Boehringer Ingelheim International Gmbh | Powder formulations for inhalation, comprising enantiomerically pure beta agonists |
| MX2008001976A (es) * | 2005-08-15 | 2008-03-25 | Boehringer Ingelheim Int | Procedimiento para la preparacion de betamimeticos. |
| CA2660186A1 (en) * | 2006-08-07 | 2008-02-14 | Boehringer Ingelheim International Gmbh | Pharmaceutical combinations for the treatment of respiratory diseases |
| WO2008017638A1 (de) * | 2006-08-07 | 2008-02-14 | Boehringer Ingelheim International Gmbh | Enantiomerenreine betaagonisten, verfahren zu deren herstellung und deren verwendung als arzneimittel |
| GB0913342D0 (en) | 2009-07-31 | 2009-09-16 | Astrazeneca Ab | Compounds - 801 |
| WO2011048409A1 (en) | 2009-10-20 | 2011-04-28 | Astrazeneca Ab | Cyclic amine derivatives having beta2 adrenergic receptor agonist and muscarinic receptor antagonist activity |
| GB201009801D0 (en) | 2010-06-11 | 2010-07-21 | Astrazeneca Ab | Compounds 950 |
| JO3192B1 (ar) | 2011-09-06 | 2018-03-08 | Novartis Ag | مركب بنزوثيازولون |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2609645A1 (de) * | 1976-03-09 | 1977-09-15 | Boehringer Sohn Ingelheim | Aminoalkylheterocyclen |
| US4460581A (en) * | 1982-10-12 | 1984-07-17 | Boehringer Ingelheim Kg | (1-Hydroxy-2-amino-alkyl)-substituted benzoxazinones and benzoxazolinones |
| IL152140A0 (en) | 2000-04-27 | 2003-05-29 | Boehringer Ingelheim Pharma | Novel, slow-acting betamimetics, a method for their production and their use as medicaments |
| DE10130371A1 (de) * | 2001-06-23 | 2003-01-02 | Boehringer Ingelheim Pharma | Neue Arzneimittelkompositionen auf der Basis von Anticholinergika, Corticosteroiden und Betamimetika |
| AR040962A1 (es) * | 2002-08-09 | 2005-04-27 | Novartis Ag | Compuestos derivados de tiazol 1,3-2-ona, composicion farmaceutica y proceso de preparacion del compuesto |
| DE10253282A1 (de) * | 2002-11-15 | 2004-05-27 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue Arzneimittel zur Behandlung von chronisch obstruktiver Lungenerkrankung |
| US7056916B2 (en) * | 2002-11-15 | 2006-06-06 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Medicaments for the treatment of chronic obstructive pulmonary disease |
| JP4516064B2 (ja) * | 2003-04-04 | 2010-08-04 | ノバルティス アーゲー | 気道疾患の処置のためのキノリン−２−オン誘導体 |
| EP1651221B1 (en) * | 2003-07-28 | 2009-01-14 | Boehringer Ingelheim International Gmbh | Medicaments for inhalation comprising betamimetics and an anticholinergic agent |
| EP1654001A2 (en) * | 2003-08-05 | 2006-05-10 | Boehringer Ingelheim International GmbH | Medicaments for inhalation comprising steroids and a betamimetic |
| JP4916317B2 (ja) * | 2004-02-14 | 2012-04-11 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 新規持続作用性β−２−アゴニスト及び薬剤としてのその使用 |
| US7405232B2 (en) * | 2004-02-14 | 2008-07-29 | Boehringer Ingelheim International Gmbh | Long acting beta-2 agonists and their use as medicaments |
| DE102004024454A1 (de) | 2004-05-14 | 2005-12-08 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue Enantiomerenreine Betaagonisten, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel |
| US7745621B2 (en) * | 2004-05-14 | 2010-06-29 | Boehringer Ingelheim International Gmbh | Long acting bronchodilators for the treatment of respiratory diseases |
| DE102004024453A1 (de) * | 2004-05-14 | 2006-01-05 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue langwirksame Bronchodilatoren zur Behandlung von Atemwegserkrankungen |
-
2005
- 2005-02-19 DE DE102005007654A patent/DE102005007654A1/de not_active Withdrawn
-
2006
- 2006-02-13 JP JP2007555588A patent/JP5140434B2/ja not_active Expired - Fee Related
- 2006-02-13 CA CA002598355A patent/CA2598355A1/en not_active Abandoned
- 2006-02-13 EP EP06708235A patent/EP1853596B1/de not_active Not-in-force
- 2006-02-13 DE DE502006008804T patent/DE502006008804D1/de active Active
- 2006-02-13 AT AT06708235T patent/ATE496913T1/de active
- 2006-02-13 WO PCT/EP2006/050898 patent/WO2006087315A1/de active Application Filing
- 2006-02-13 ES ES06708235T patent/ES2357620T3/es active Active
- 2006-02-15 US US11/355,065 patent/US7423036B2/en active Active
- 2006-02-17 TW TW095105331A patent/TW200640911A/zh unknown
- 2006-02-17 AR ARP060100567A patent/AR053135A1/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EP1853596B1 (de) | 2011-01-26 |
| DE102005007654A1 (de) | 2006-08-24 |
| DE502006008804D1 (de) | 2011-03-10 |
| EP1853596A1 (de) | 2007-11-14 |
| CA2598355A1 (en) | 2006-08-24 |
| US20060189607A1 (en) | 2006-08-24 |
| JP5140434B2 (ja) | 2013-02-06 |
| ES2357620T3 (es) | 2011-04-28 |
| WO2006087315A1 (de) | 2006-08-24 |
| JP2008530176A (ja) | 2008-08-07 |
| TW200640911A (en) | 2006-12-01 |
| US7423036B2 (en) | 2008-09-09 |
| ATE496913T1 (de) | 2011-02-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal |