AR049059A1 - Composiciones farmaceuticas de 4-(4bromo-2fluroanilino)-6-metoxi-7-(1-metilpiperidin-4ilmetoxi)quinazolina - Google Patents

Composiciones farmaceuticas de 4-(4bromo-2fluroanilino)-6-metoxi-7-(1-metilpiperidin-4ilmetoxi)quinazolina

Info

Publication number
AR049059A1
AR049059A1 ARP050102087A ARP050102087A AR049059A1 AR 049059 A1 AR049059 A1 AR 049059A1 AR P050102087 A ARP050102087 A AR P050102087A AR P050102087 A ARP050102087 A AR P050102087A AR 049059 A1 AR049059 A1 AR 049059A1
Authority
AR
Argentina
Prior art keywords
methylipiperidin
4ilmetoxy
quinazolina
metoxi
4bromo
Prior art date
Application number
ARP050102087A
Other languages
English (en)
Inventor
Paul William Stott
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of AR049059A1 publication Critical patent/AR049059A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Steroid Compounds (AREA)

Abstract

Una composicion farmacéutica que comprende ZD6474, o una sal de éste aceptable para el uso farmacéutico, un diluyente frágil, como por ejemplo fosfato de calcio dibásico y un segundo diluyente que es prácticamente insoluble y tiene propiedades de compresion ductil, como por ejemplo celulosa microcristalina, que presenta actividad antitumoral.
ARP050102087A 2004-05-21 2005-05-20 Composiciones farmaceuticas de 4-(4bromo-2fluroanilino)-6-metoxi-7-(1-metilpiperidin-4ilmetoxi)quinazolina AR049059A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0411378.3A GB0411378D0 (en) 2004-05-21 2004-05-21 Pharmaceutical compositions

Publications (1)

Publication Number Publication Date
AR049059A1 true AR049059A1 (es) 2006-06-21

Family

ID=32607743

Family Applications (2)

Application Number Title Priority Date Filing Date
ARP050102087A AR049059A1 (es) 2004-05-21 2005-05-20 Composiciones farmaceuticas de 4-(4bromo-2fluroanilino)-6-metoxi-7-(1-metilpiperidin-4ilmetoxi)quinazolina
ARP170103128A AR110045A2 (es) 2004-05-21 2017-11-09 Composiciones farmacéuticas

Family Applications After (1)

Application Number Title Priority Date Filing Date
ARP170103128A AR110045A2 (es) 2004-05-21 2017-11-09 Composiciones farmacéuticas

Country Status (34)

Country Link
US (1) US8067427B2 (es)
EP (1) EP1753431B1 (es)
JP (1) JP4740947B2 (es)
KR (1) KR101192935B1 (es)
CN (1) CN101031303B (es)
AR (2) AR049059A1 (es)
AT (1) ATE439841T1 (es)
AU (1) AU2005244650B2 (es)
BR (1) BRPI0511253B8 (es)
CA (1) CA2565513C (es)
CY (1) CY1109500T1 (es)
DE (1) DE602005016105D1 (es)
DK (1) DK1753431T3 (es)
ES (1) ES2330025T3 (es)
GB (1) GB0411378D0 (es)
HK (1) HK1099220A1 (es)
HR (1) HRP20090547T1 (es)
IL (1) IL178928A (es)
ME (2) ME02778B (es)
MX (1) MXPA06013501A (es)
MY (1) MY138868A (es)
NO (1) NO338324B1 (es)
NZ (1) NZ550931A (es)
PL (1) PL1753431T3 (es)
PT (1) PT1753431E (es)
RS (1) RS51112B (es)
RU (1) RU2383343C2 (es)
SA (1) SA05260133B1 (es)
SI (1) SI1753431T1 (es)
TW (1) TWI355269B (es)
UA (1) UA81732C2 (es)
UY (1) UY28901A1 (es)
WO (1) WO2005112934A1 (es)
ZA (1) ZA200609110B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2278511B1 (es) * 2005-07-28 2008-06-16 Laboratorios Almirall S.A. Comprimidos con perfil de disolucion mejorado.
EP3039424B1 (en) 2013-08-28 2020-07-29 Crown Bioscience, Inc. (Taicang) Gene expression signatures predictive of subject response to a multi-kinase inhibitor and methods of using the same

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9718972D0 (en) 1996-09-25 1997-11-12 Zeneca Ltd Chemical compounds
MXPA02004366A (es) * 1999-11-05 2002-11-07 Astrazeneca Ab Derivados de quinazolina como inhibidores vegf.
GB0001621D0 (en) * 2000-01-26 2000-03-15 Astrazeneca Ab Pharmaceutical compositions
KR100419555B1 (ko) * 2000-05-29 2004-02-19 주식회사유한양행 비형간염바이러스의 에스-표면항원을 인식하는단일클론항체의 가변영역 및 이를 코딩하는 유전자
WO2003074045A1 (fr) * 2002-03-05 2003-09-12 Eisai Co., Ltd. Agent antitumoral comprenant une combinaison d'un compose heterocyclique contenant un sulfamide et d'un inhibiteur d'angiogenese

Also Published As

Publication number Publication date
CA2565513C (en) 2010-10-19
KR101192935B1 (ko) 2012-10-18
NZ550931A (en) 2009-05-31
NO338324B1 (no) 2016-08-08
BRPI0511253B8 (pt) 2021-05-25
UA81732C2 (ru) 2008-01-25
MXPA06013501A (es) 2007-06-12
ZA200609110B (en) 2008-06-25
RS51112B (sr) 2010-10-31
HRP20090547T1 (en) 2009-11-30
DE602005016105D1 (de) 2009-10-01
ES2330025T3 (es) 2009-12-03
CA2565513A1 (en) 2005-12-01
US20070244323A1 (en) 2007-10-18
PL1753431T3 (pl) 2009-12-31
ME01505B (me) 2014-04-20
ATE439841T1 (de) 2009-09-15
IL178928A (en) 2012-04-30
AU2005244650A1 (en) 2005-12-01
ME02778B (me) 2010-10-31
EP1753431A1 (en) 2007-02-21
CY1109500T1 (el) 2014-08-13
NO20065735L (no) 2006-12-19
TWI355269B (en) 2012-01-01
UY28901A1 (es) 2005-12-30
SA05260133B1 (ar) 2008-12-23
CN101031303B (zh) 2011-08-31
US8067427B2 (en) 2011-11-29
HK1099220A1 (en) 2007-08-10
TW200612953A (en) 2006-05-01
JP2007538060A (ja) 2007-12-27
BRPI0511253A (pt) 2007-11-27
SI1753431T1 (sl) 2009-12-31
EP1753431B1 (en) 2009-08-19
GB0411378D0 (en) 2004-06-23
RU2383343C2 (ru) 2010-03-10
JP4740947B2 (ja) 2011-08-03
BRPI0511253B1 (pt) 2020-03-31
KR20070034499A (ko) 2007-03-28
DK1753431T3 (da) 2009-11-16
IL178928A0 (en) 2007-03-08
MY138868A (en) 2009-08-28
AR110045A2 (es) 2019-02-20
WO2005112934A1 (en) 2005-12-01
PT1753431E (pt) 2009-10-14
RU2006145357A (ru) 2008-06-27
CN101031303A (zh) 2007-09-05
AU2005244650B2 (en) 2008-04-10

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