AR048193A1 - Procedimiento para la preparacion de una composicion secada por pulverizacion que comprende talnetant, composicion farmaceutica obtenida segun dicho procedimiento y forma de dosificacion que comprende la mencionada composicion - Google Patents
Procedimiento para la preparacion de una composicion secada por pulverizacion que comprende talnetant, composicion farmaceutica obtenida segun dicho procedimiento y forma de dosificacion que comprende la mencionada composicionInfo
- Publication number
- AR048193A1 AR048193A1 ARP050101190A ARP050101190A AR048193A1 AR 048193 A1 AR048193 A1 AR 048193A1 AR P050101190 A ARP050101190 A AR P050101190A AR P050101190 A ARP050101190 A AR P050101190A AR 048193 A1 AR048193 A1 AR 048193A1
- Authority
- AR
- Argentina
- Prior art keywords
- procedure
- composition
- talnetant
- preparation
- dosage
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
- A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pulmonology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Un procedimiento para la preparacion de una composicion secada por pulverizacion, comprendiendo la composicion i) partículas de talnetant que tienen un Dv90 en el intervalo de 0,1 a 2,0 (mu)m, ii) uno o varios tensioactivos ionicos e iii) uno o varios vehículos solubles, comprendiendo el procedimiento a) moles en humedo una dispersion de partículas solidas de talnetant hasta un Dv90 que esté en el intervalo de 0,1 a 2,0 (mu)m, cuya dispersion comprende uno o varios tensioactivos ionicos y uno o varios vehículos solubles, después b) secar por pulverizacion o granular por pulverizacion la dispersion resultante. El talnetant es un antagonista de receptor de NK3 y las composiciones así obtenidas tienen mayor biodisponibilidad. Composicion farmacéutica obtenida mediante dicho procedimiento y forma de dosificacion que comprende esta ultima.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US55757104P | 2004-03-30 | 2004-03-30 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR048193A1 true AR048193A1 (es) | 2006-04-05 |
Family
ID=34956393
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP050101190A AR048193A1 (es) | 2004-03-30 | 2005-03-28 | Procedimiento para la preparacion de una composicion secada por pulverizacion que comprende talnetant, composicion farmaceutica obtenida segun dicho procedimiento y forma de dosificacion que comprende la mencionada composicion |
Country Status (27)
Country | Link |
---|---|
US (1) | US20070178151A1 (es) |
EP (1) | EP1729734B1 (es) |
JP (1) | JP2007530702A (es) |
KR (1) | KR20060135000A (es) |
CN (1) | CN1933816A (es) |
AR (1) | AR048193A1 (es) |
AT (1) | ATE387189T1 (es) |
AU (1) | AU2005231355B2 (es) |
BR (1) | BRPI0508111A (es) |
CA (1) | CA2556461A1 (es) |
DE (1) | DE602005005033T2 (es) |
DK (1) | DK1729734T3 (es) |
ES (1) | ES2301003T3 (es) |
HK (1) | HK1099213A1 (es) |
HR (1) | HRP20080154T3 (es) |
IL (1) | IL177606A0 (es) |
IS (1) | IS8548A (es) |
MA (1) | MA28557B1 (es) |
NO (1) | NO20064864L (es) |
NZ (1) | NZ549096A (es) |
PE (1) | PE20060161A1 (es) |
PL (1) | PL1729734T3 (es) |
PT (1) | PT1729734E (es) |
RU (1) | RU2006138054A (es) |
TW (1) | TW200602055A (es) |
WO (1) | WO2005097077A2 (es) |
ZA (1) | ZA200606670B (es) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0506800D0 (en) * | 2005-04-04 | 2005-05-11 | Merck Sharp & Dohme | New uses |
TW200803854A (en) * | 2005-09-30 | 2008-01-16 | Smithkline Beecham Corp | Pharmaceutical compositions |
EP1940357A2 (en) * | 2005-09-30 | 2008-07-09 | SmithKline Beecham Corporation | Pharmaceutical compositions |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5145684A (en) * | 1991-01-25 | 1992-09-08 | Sterling Drug Inc. | Surface modified drug nanoparticles |
ES2227769T3 (es) * | 1994-05-27 | 2005-04-01 | Glaxosmithkline S.P.A. | Derivados de quinolina como antagonistas del receptor nk3 de taquiquinina. |
US6936277B2 (en) * | 1995-01-09 | 2005-08-30 | J. Rettenmaier & Soehne Gmbh & Co. Kg | Pharmaceutical excipient having improved compressibility |
DE19501269A1 (de) * | 1995-01-18 | 1996-07-25 | Henkel Kgaa | Amorphes Alkalisilikat-Compound |
US20040013613A1 (en) * | 2001-05-18 | 2004-01-22 | Jain Rajeev A | Rapidly disintegrating solid oral dosage form |
ATE367802T1 (de) * | 2000-09-20 | 2007-08-15 | Jagotec Ag | Verfahren zur sprühtrocknung von zusammensetzungen enthaltend fenofibrat |
US6620438B2 (en) * | 2001-03-08 | 2003-09-16 | Boehringer Ingelheim Pharma Kg | Pharmaceutical compositions based on anticholinergics and NK1-receptor antagonists |
MY134211A (en) * | 2001-05-18 | 2007-11-30 | Smithkline Beecham Corp | Novel use |
ATE371442T1 (de) * | 2001-10-12 | 2007-09-15 | Elan Pharma Int Ltd | Zusammensetzungen mit einer kombination aus eigenschaften sofortiger freisetzung und kontrollierter freisetzung |
-
2005
- 2005-03-28 BR BRPI0508111-4A patent/BRPI0508111A/pt not_active IP Right Cessation
- 2005-03-28 EP EP05730200A patent/EP1729734B1/en active Active
- 2005-03-28 US US10/593,653 patent/US20070178151A1/en not_active Abandoned
- 2005-03-28 CA CA002556461A patent/CA2556461A1/en not_active Abandoned
- 2005-03-28 AT AT05730200T patent/ATE387189T1/de not_active IP Right Cessation
- 2005-03-28 CN CNA2005800096272A patent/CN1933816A/zh active Pending
- 2005-03-28 TW TW094109502A patent/TW200602055A/zh unknown
- 2005-03-28 PL PL05730200T patent/PL1729734T3/pl unknown
- 2005-03-28 NZ NZ549096A patent/NZ549096A/en unknown
- 2005-03-28 KR KR1020067019646A patent/KR20060135000A/ko not_active Application Discontinuation
- 2005-03-28 WO PCT/US2005/010350 patent/WO2005097077A2/en active IP Right Grant
- 2005-03-28 AU AU2005231355A patent/AU2005231355B2/en not_active Ceased
- 2005-03-28 AR ARP050101190A patent/AR048193A1/es not_active Application Discontinuation
- 2005-03-28 PT PT05730200T patent/PT1729734E/pt unknown
- 2005-03-28 DK DK05730200T patent/DK1729734T3/da active
- 2005-03-28 RU RU2006138054/15A patent/RU2006138054A/ru not_active Application Discontinuation
- 2005-03-28 JP JP2007506436A patent/JP2007530702A/ja not_active Withdrawn
- 2005-03-28 ES ES05730200T patent/ES2301003T3/es active Active
- 2005-03-28 PE PE2005000347A patent/PE20060161A1/es not_active Application Discontinuation
- 2005-03-28 DE DE602005005033T patent/DE602005005033T2/de active Active
-
2006
- 2006-08-11 ZA ZA200606670A patent/ZA200606670B/xx unknown
- 2006-08-21 IL IL177606A patent/IL177606A0/en unknown
- 2006-10-06 IS IS8548A patent/IS8548A/is unknown
- 2006-10-25 NO NO20064864A patent/NO20064864L/no not_active Application Discontinuation
- 2006-10-30 MA MA29420A patent/MA28557B1/fr unknown
-
2007
- 2007-05-23 HK HK07105477.4A patent/HK1099213A1/xx not_active IP Right Cessation
-
2008
- 2008-04-02 HR HR20080154T patent/HRP20080154T3/xx unknown
Also Published As
Publication number | Publication date |
---|---|
DE602005005033T2 (de) | 2009-03-19 |
MA28557B1 (fr) | 2007-04-03 |
WO2005097077A2 (en) | 2005-10-20 |
EP1729734A2 (en) | 2006-12-13 |
AU2005231355B2 (en) | 2008-09-18 |
ES2301003T3 (es) | 2008-06-16 |
AU2005231355A1 (en) | 2005-10-20 |
IS8548A (is) | 2006-10-06 |
DK1729734T3 (da) | 2008-06-16 |
CN1933816A (zh) | 2007-03-21 |
NO20064864L (no) | 2006-10-25 |
RU2006138054A (ru) | 2008-05-10 |
ATE387189T1 (de) | 2008-03-15 |
EP1729734B1 (en) | 2008-02-27 |
NZ549096A (en) | 2009-05-31 |
CA2556461A1 (en) | 2005-10-20 |
BRPI0508111A (pt) | 2007-07-17 |
DE602005005033D1 (de) | 2008-04-10 |
WO2005097077A3 (en) | 2006-04-13 |
HK1099213A1 (en) | 2007-08-10 |
KR20060135000A (ko) | 2006-12-28 |
ZA200606670B (en) | 2008-01-30 |
TW200602055A (en) | 2006-01-16 |
JP2007530702A (ja) | 2007-11-01 |
US20070178151A1 (en) | 2007-08-02 |
HRP20080154T3 (en) | 2008-10-31 |
PL1729734T3 (pl) | 2008-09-30 |
PT1729734E (pt) | 2008-05-29 |
IL177606A0 (en) | 2006-12-10 |
PE20060161A1 (es) | 2006-05-10 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA | Abandonment or withdrawal |