EA201001312A1 - Твердая фармацевтическая композиция, содержащая непептидный антагонист рецептора ангиотензина ii и диуретик - Google Patents

Твердая фармацевтическая композиция, содержащая непептидный антагонист рецептора ангиотензина ii и диуретик

Info

Publication number
EA201001312A1
EA201001312A1 EA201001312A EA201001312A EA201001312A1 EA 201001312 A1 EA201001312 A1 EA 201001312A1 EA 201001312 A EA201001312 A EA 201001312A EA 201001312 A EA201001312 A EA 201001312A EA 201001312 A1 EA201001312 A1 EA 201001312A1
Authority
EA
Eurasian Patent Office
Prior art keywords
diuretic
pharmaceutical composition
composition containing
angiotensin
solid pharmaceutical
Prior art date
Application number
EA201001312A
Other languages
English (en)
Inventor
Сунил Р. Мхазе
Ганеш В. Гат
Джавед Хуссаин
Original Assignee
Рациофарм Гмбх
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40589972&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EA201001312(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Рациофарм Гмбх filed Critical Рациофарм Гмбх
Publication of EA201001312A1 publication Critical patent/EA201001312A1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/549—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame having two or more nitrogen atoms in the same ring, e.g. hydrochlorothiazide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

В заявке описана твердая фармацевтическая композиция, содержащая по меньшей мере два слоя, в которой первый слой включает непептидный антагонист рецептора ангиотензина II или его фармацевтически приемлемую соль в растворяющемся матриксе, а второй слой включает диуретик или его фармацевтически приемлемую соль. В заявке описаны также способы получения указанных фармацевтических композиций.
EA201001312A 2008-03-19 2009-03-17 Твердая фармацевтическая композиция, содержащая непептидный антагонист рецептора ангиотензина ii и диуретик EA201001312A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN700DE2008 2008-03-19
PCT/EP2009/001966 WO2009115301A1 (en) 2008-03-19 2009-03-17 Solid pharmaceutical composition comprising a non-peptide angiotensin ii receptor antagonist and a diuretic

Publications (1)

Publication Number Publication Date
EA201001312A1 true EA201001312A1 (ru) 2011-04-29

Family

ID=40589972

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201001312A EA201001312A1 (ru) 2008-03-19 2009-03-17 Твердая фармацевтическая композиция, содержащая непептидный антагонист рецептора ангиотензина ii и диуретик

Country Status (8)

Country Link
US (1) US20110008428A1 (ru)
EP (1) EP2252273B1 (ru)
CA (1) CA2715350C (ru)
EA (1) EA201001312A1 (ru)
ES (1) ES2623329T3 (ru)
PL (1) PL2252273T3 (ru)
SI (1) SI2252273T1 (ru)
WO (1) WO2009115301A1 (ru)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL2252273T3 (pl) 2008-03-19 2017-07-31 Ratiopharm Gmbh Stała kompozycja farmaceutyczna zawierająca niepeptydowy związek antagonistyczny receptora angiotensyny II i środek moczopędny
GB0822171D0 (en) * 2008-12-04 2009-01-14 Arrow Int Ltd Temisartan formulations
US9387249B2 (en) 2008-12-23 2016-07-12 Takeda Pharmaceutical Company Limited Methods of treating hypertension with at least one angiotensin II receptor blocker and chlorthalidone
TR201004754A1 (tr) * 2010-06-11 2012-01-23 Sanovel �La� San. Ve T�C. A.�. Yeni Farmasötik Kombinasyonlar
US9216169B2 (en) * 2011-12-23 2015-12-22 Tianjin Institute Of Pharmaceutical Research Pharmaceutical composition comprising candesartan or ester thereof and chlortalidone, and use thereof
EP2612658A1 (en) 2012-01-05 2013-07-10 Laboratorios Lesvi, S.L. Pharmaceutical compositions of 4'-[(1,4'dimethyl-2'-propyl[2,6'-bi-1h-benzimidazol]-1'-yl)methyl]-[1,1'-biphenyl]-2-carboxylic acid and is 6-chloro-3,4-dihydro-2h-1,2,4-benzothiadiazine-7-sulfonamide-1,1-dioxide
BR102013028883A2 (pt) * 2013-11-08 2015-10-06 Hypermarcas S A forma farmacêutica oral para a prevenção de doenças vasculares, comprimido como forma farmacêutica e cápsula gelatinosa como forma farmacêutica
JP6428340B2 (ja) * 2014-05-23 2018-11-28 ニプロ株式会社 テルミサルタンを含む医薬組成物の造粒方法
EP4373474A1 (en) 2021-07-22 2024-05-29 KRKA, D.D., Novo Mesto Bilayer tablet comprising telmisartan and indapamide
EP4295839A1 (en) 2022-06-20 2023-12-27 KRKA, d.d., Novo mesto Combination of valsartan and indapamide

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK8603837A (ru) * 1985-08-13 1987-02-14
ES2074769T3 (es) * 1991-07-01 1995-09-16 Gergely Gerhard Procedimiento para la elaboracion de un preparado farmaceutico con, al menos, dos principios activos diferentes y uso de un preparado de este tipo.
FR2766708B1 (fr) 1997-07-30 2000-05-05 Galenix Dev Composition contenant de l'hydroxypropylcellulose, de l'hydroxypropylmethylcellulose et/ou de l'ethylcellullose a titre d'agents desintegrants, et procede d'obtention
US6358986B1 (en) * 1999-01-19 2002-03-19 Boehringer Ingelheim Pharma Kg Polymorphs of telmisartan
EP2260833B1 (en) * 2002-01-16 2012-11-21 Boehringer Ingelheim Pharma GmbH & Co. KG Bilayer pharmaceutical tablet comprising telmisartan and a diuretic
US8980870B2 (en) * 2002-09-24 2015-03-17 Boehringer Ingelheim International Gmbh Solid telmisartan pharmaceutical formulations
WO2005082329A2 (en) 2004-02-19 2005-09-09 Ranbaxy Laboratories Limited Process for the preparation of solid dosage forms of valsartan and hydrochlorthiazide
DE102004008804A1 (de) 2004-02-20 2005-09-08 Boehringer Ingelheim Pharma Gmbh & Co. Kg Mehrschichttablette
CN101080225A (zh) 2004-12-17 2007-11-28 贝林格尔·英格海姆国际有限公司 包含替米沙坦及氢氯噻嗪的组合治疗
US8637078B2 (en) 2005-11-24 2014-01-28 Boehringer Ingelheim International Gmbh Bilayer tablet comprising telmisartan and diuretic
CA2654890C (en) 2006-06-16 2015-10-06 Lek Pharmaceuticals D.D. Pharmaceutical composition
US20100247649A1 (en) 2007-10-30 2010-09-30 Dr. Reddy's Laboratories Ltd. Pharmaceutical formulations comprising telmisartan and hydrochlorothiazide
PL2252273T3 (pl) 2008-03-19 2017-07-31 Ratiopharm Gmbh Stała kompozycja farmaceutyczna zawierająca niepeptydowy związek antagonistyczny receptora angiotensyny II i środek moczopędny

Also Published As

Publication number Publication date
US20110008428A1 (en) 2011-01-13
WO2009115301A1 (en) 2009-09-24
ES2623329T3 (es) 2017-07-11
CA2715350C (en) 2017-02-14
PL2252273T3 (pl) 2017-07-31
SI2252273T1 (sl) 2017-06-30
EP2252273B1 (en) 2016-12-28
EP2252273A1 (en) 2010-11-24
CA2715350A1 (en) 2009-09-24

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