AR047553A1 - La combinacion de un inhibidor de reabsorcion de serotonina y agomelatina - Google Patents
La combinacion de un inhibidor de reabsorcion de serotonina y agomelatinaInfo
- Publication number
- AR047553A1 AR047553A1 ARP040102269A ARP040102269A AR047553A1 AR 047553 A1 AR047553 A1 AR 047553A1 AR P040102269 A ARP040102269 A AR P040102269A AR P040102269 A ARP040102269 A AR P040102269A AR 047553 A1 AR047553 A1 AR 047553A1
- Authority
- AR
- Argentina
- Prior art keywords
- agomelatine
- combination
- inhibitor
- reabsortion
- serotonine
- Prior art date
Links
- QZAYGJVTTNCVMB-UHFFFAOYSA-N serotonin Chemical compound C1=C(O)C=C2C(CCN)=CNC2=C1 QZAYGJVTTNCVMB-UHFFFAOYSA-N 0.000 title abstract 3
- YJYPHIXNFHFHND-UHFFFAOYSA-N agomelatine Chemical compound C1=CC=C(CCNC(C)=O)C2=CC(OC)=CC=C21 YJYPHIXNFHFHND-UHFFFAOYSA-N 0.000 title abstract 2
- 229960002629 agomelatine Drugs 0.000 title abstract 2
- 239000003112 inhibitor Substances 0.000 title 1
- 208000020401 Depressive disease Diseases 0.000 abstract 1
- 208000019022 Mood disease Diseases 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229940076279 serotonin Drugs 0.000 abstract 1
- 229940126570 serotonin reuptake inhibitor Drugs 0.000 abstract 1
- 239000003772 serotonin uptake inhibitor Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/48—Ergoline derivatives, e.g. lysergic acid, ergotamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Endocrinology (AREA)
- Anesthesiology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Hospice & Palliative Care (AREA)
- Addiction (AREA)
- Diabetes (AREA)
- Reproductive Health (AREA)
- Child & Adolescent Psychology (AREA)
- Nutrition Science (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA200301031 | 2003-07-04 | ||
| US48547903P | 2003-07-07 | 2003-07-07 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR047553A1 true AR047553A1 (es) | 2006-01-25 |
Family
ID=33566216
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP040102269A AR047553A1 (es) | 2003-07-04 | 2004-06-28 | La combinacion de un inhibidor de reabsorcion de serotonina y agomelatina |
Country Status (17)
| Country | Link |
|---|---|
| US (3) | US20060205754A1 (enExample) |
| EP (1) | EP1643985B1 (enExample) |
| JP (1) | JP2007513052A (enExample) |
| KR (1) | KR20060032598A (enExample) |
| CN (1) | CN1852706A (enExample) |
| AR (1) | AR047553A1 (enExample) |
| AT (1) | ATE499096T1 (enExample) |
| AU (1) | AU2004253225A1 (enExample) |
| BR (1) | BRPI0411665A (enExample) |
| CA (1) | CA2530880A1 (enExample) |
| DE (1) | DE602004031527D1 (enExample) |
| DK (1) | DK1643985T3 (enExample) |
| IL (1) | IL172965A0 (enExample) |
| IS (1) | IS8154A (enExample) |
| MX (1) | MXPA06000018A (enExample) |
| NO (1) | NO20060242L (enExample) |
| WO (1) | WO2005002562A1 (enExample) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2884714B1 (fr) * | 2005-04-20 | 2011-05-06 | Servier Lab | Utilisation de l'agomelatine pour l'obtention de medicaments destines au traitement des troubles bipolaires |
| FR2890563B1 (fr) * | 2005-09-09 | 2007-10-19 | Servier Lab | Nouvelle association entre l'agomelatine et un agent thymoregulateur et les compositions pharmaceutiques qui la contiennent |
| FR2890564B1 (fr) * | 2005-09-09 | 2007-10-19 | Servier Lab | Nouvelle association entre l'agomelatine et un inhibiteur de la recapture de la noradrenaline et les compositions pharmaceutiques qui la contiennent |
| FR2899472B1 (fr) * | 2006-04-07 | 2008-09-12 | Servier Lab | Utilisation de l'agomelatine pour l'obtention de medicaments destines au traitement du trouble anxiete generalisee |
| WO2008035177A2 (en) * | 2006-09-18 | 2008-03-27 | Copharm | Combination of mt1 and mt2 melatonin receptor agonists and a norepinephrine/dopamine reuptake inhibitor |
| US7608737B2 (en) | 2007-05-01 | 2009-10-27 | Concert Pharmaceuticasl Inc. | Naphthyl(ethyl)acetamides |
| WO2008141033A1 (en) * | 2007-05-08 | 2008-11-20 | Auspex Pharmaceuticals Inc. | Substituted naphthalenes |
| FR2956031B1 (fr) * | 2010-02-11 | 2012-03-02 | Servier Lab | Utilisation de l'agomelatine pour l'obtention de medicaments destines au traitement du trouble obsessionnel compulsif (toc) |
| WO2012054815A1 (en) | 2010-10-22 | 2012-04-26 | Duke University | Slow-release formulations of 5-hydroxytryptophan as an adjunct to pro-serotonergic therapies |
| PL2517700T3 (pl) * | 2011-04-28 | 2013-12-31 | Zentiva Ks | Farmaceutyczne dopuszczalne kokryształy n-[2-(7-metoksy-1-naftylo]acetamidu i sposoby ich wytwarzania |
| PH12012000132A1 (en) * | 2011-06-09 | 2014-10-20 | Servier Lab | New co-crystals of agomelatine, a process for their preparation and pharmaceutical compositions containing them |
| WO2013013060A1 (en) * | 2011-07-19 | 2013-01-24 | Lycus, Llc | Agomelatine derivatives |
| EP2551257A1 (en) * | 2011-07-28 | 2013-01-30 | Laboratorios Del. Dr. Esteve, S.A. | Co-crystals of agomelatine with co-crystal-formers |
| WO2014024896A1 (ja) * | 2012-08-08 | 2014-02-13 | 株式会社メドレックス | アゴメラチンを含有する貼付剤組成物 |
| WO2023154794A1 (en) * | 2022-02-09 | 2023-08-17 | University Of North Texas Health Science Center | Drug repurposing for delayed treatment of ischemic stroke |
| CN116570579A (zh) * | 2023-06-13 | 2023-08-11 | 深圳市泛谷药业股份有限公司 | 一种含有阿戈美拉汀和氟伏沙明的药物组合物及其应用 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2658818B1 (fr) | 1990-02-27 | 1993-12-31 | Adir Cie | Nouveaux derives a structure naphtalenique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
| US5470846A (en) * | 1994-01-14 | 1995-11-28 | Sandyk; Reuven | Treatment of neurological and mental disorders |
| CA2134038C (en) | 1994-06-16 | 1997-06-03 | David Taiwai Wong | Potentiation of drug response |
| CA2194984C (en) | 1994-07-26 | 2002-07-02 | John Eugene Macor | 4-indole derivatives as serotonin agonists and antagonists |
| US5597826A (en) | 1994-09-14 | 1997-01-28 | Pfizer Inc. | Compositions containing sertraline and a 5-HT1D receptor agonist or antagonist |
| EP0714663A3 (en) | 1994-11-28 | 1997-01-15 | Lilly Co Eli | Potentiation of drug responses by serotonin 1A receptor antagonists |
| FR2744449B1 (fr) | 1996-02-02 | 1998-04-24 | Pf Medicament | Nouvelles piperazines aromatiques derivees de cycloazanes substitues, ainsi que leur procede de preparation, les compositions pharmaceutiques et leur utilisation comme medicaments |
| SE9703375D0 (sv) | 1997-09-18 | 1997-09-18 | Astra Ab | A new combination |
| GB2336534A (en) * | 1998-04-24 | 1999-10-27 | Alec James Coppen | Anti-depressant - Folic Acid Combination |
| UA77650C2 (en) * | 1999-12-06 | 2007-01-15 | Lundbeck & Co As H | Use of serotonin reuptake inhibitor in combination with deramcyclane |
| CN1509169A (zh) * | 2001-05-01 | 2004-06-30 | H��¡�±�������˾ | 对映体纯艾司西酞普兰的用途 |
| US6617891B2 (en) * | 2001-09-26 | 2003-09-09 | Intel Corporation | Slew rate at buffers by isolating predriver from driver |
| FR2834890B1 (fr) * | 2002-01-23 | 2004-02-27 | Servier Lab | Composition pharmaceutique orodispersible d'agomelatine |
-
2004
- 2004-06-28 AR ARP040102269A patent/AR047553A1/es unknown
- 2004-06-29 CN CNA2004800191380A patent/CN1852706A/zh active Pending
- 2004-06-29 WO PCT/DK2004/000464 patent/WO2005002562A1/en not_active Ceased
- 2004-06-29 JP JP2006517965A patent/JP2007513052A/ja active Pending
- 2004-06-29 EP EP04738961A patent/EP1643985B1/en not_active Expired - Lifetime
- 2004-06-29 MX MXPA06000018A patent/MXPA06000018A/es not_active Application Discontinuation
- 2004-06-29 KR KR1020057024442A patent/KR20060032598A/ko not_active Withdrawn
- 2004-06-29 DK DK04738961.4T patent/DK1643985T3/da active
- 2004-06-29 BR BRPI0411665-8A patent/BRPI0411665A/pt not_active Application Discontinuation
- 2004-06-29 CA CA002530880A patent/CA2530880A1/en not_active Abandoned
- 2004-06-29 DE DE602004031527T patent/DE602004031527D1/de not_active Expired - Lifetime
- 2004-06-29 AU AU2004253225A patent/AU2004253225A1/en not_active Abandoned
- 2004-06-29 US US10/558,494 patent/US20060205754A1/en not_active Abandoned
- 2004-06-29 AT AT04738961T patent/ATE499096T1/de not_active IP Right Cessation
-
2005
- 2005-11-28 IS IS8154A patent/IS8154A/is unknown
-
2006
- 2006-01-03 IL IL172965A patent/IL172965A0/en unknown
- 2006-01-17 NO NO20060242A patent/NO20060242L/no not_active Application Discontinuation
-
2010
- 2010-04-21 US US12/764,348 patent/US20100267772A1/en not_active Abandoned
-
2012
- 2012-07-19 US US13/552,699 patent/US20130217776A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| MXPA06000018A (es) | 2006-03-21 |
| US20060205754A1 (en) | 2006-09-14 |
| NO20060242L (no) | 2006-01-17 |
| KR20060032598A (ko) | 2006-04-17 |
| CN1852706A (zh) | 2006-10-25 |
| US20130217776A1 (en) | 2013-08-22 |
| DE602004031527D1 (de) | 2011-04-07 |
| DK1643985T3 (da) | 2011-06-06 |
| ATE499096T1 (de) | 2011-03-15 |
| IL172965A0 (en) | 2006-06-11 |
| US20100267772A1 (en) | 2010-10-21 |
| AU2004253225A1 (en) | 2005-01-13 |
| JP2007513052A (ja) | 2007-05-24 |
| BRPI0411665A (pt) | 2006-08-08 |
| CA2530880A1 (en) | 2005-01-13 |
| WO2005002562A1 (en) | 2005-01-13 |
| EP1643985A1 (en) | 2006-04-12 |
| EP1643985B1 (en) | 2011-02-23 |
| IS8154A (is) | 2005-11-28 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AR047553A1 (es) | La combinacion de un inhibidor de reabsorcion de serotonina y agomelatina | |
| NI200700250A (es) | Moduladores de fenilo y piridilo de lta4h | |
| ECSP11010975A (es) | Método de uso de una cepa de bacillus subtilis para mejorar la salud de animales | |
| MEP6208A (en) | The combination of a serotonin reuptake inhibitor and a 5-ht¿2c? antagonist, inverse agonist or partial agonist | |
| CL2007000361A1 (es) | Combinacion que comprende un inhibidor de la arn polimerasa del virus de la hepatitis c (vhc) y un inhibidor de la proteasa del vhc; composicion farmaceutica que la comprende; y uso de la combinacion para tratar trastornos asociados con vhc. | |
| BR0316535A (pt) | Composição farmacêutica de um agonista adrenoceptor beta-3 e um inibidor de reuptake de serotonina e/ou norepinefrina | |
| ECSP056229A (es) | Una composición farmacéutica que comprende formas polimórficas de 3-(4-amino-1-oxo-1.3 dyhidro-isoindol-2-il)-piperidina-2,6-diona para el tratamiento y manejo de cánceres | |
| ES2188177T3 (es) | Composicion para la prevencion y/o el tratamiento de la osteoporosis y las alteraciones debidas al sindrome menopausico, que comprende propionil-l-carnitina y genisteina. | |
| HN2004000319A (es) | "{ 1,8}naftiridin-2-onas y compuestos relacionados para el tratamiento de la esquizofrenia" | |
| CR7583A (es) | Nueva sal formiato de o-desmetil venlafaxina | |
| CL2007002384A1 (es) | Uso de compuestos derivados de 2,5-dihidroxibenceno para el tratamiento de la psoriasis. | |
| PA8577201A1 (es) | 3-fenil-propionamido, 3-fenil-acrilamido y derivados 3-fenil-propinamido como inhibidores de mao-b | |
| CL2007002380A1 (es) | Uso de compuestos derivados de 2,5-dihidroxibenceno para el tratamiento terapeutico y/o profilactico de la queratosis actinica. | |
| HRP20070552T3 (en) | Combination of mglur2 antagonist and ache inhibitor for treatment of acute and/or chronic neurological disorders | |
| ECSP088743A (es) | Anticuerpos para egfl7 y métodos para su uso | |
| CR9661A (es) | Inhibidor de la retoma dual de norepinefrina y serotonina altamente selectivo y su uso | |
| UY27610A1 (es) | Combinación de inhibidores de ptm o inhibidores de la secreción de apob con fibratos para la utilización como medicamentos | |
| BRPI0416157A (pt) | composição farmacêutica contendo um agonista de adrenoceptor beta-3 e um antagonista alfa e/ou um inibidor de 5-alfa redutase | |
| ECSP045145A (es) | Uso de inhibidores de la recaptacion de norepinefrina para el tratamiento del fallo cognitivo | |
| FI20031191A7 (fi) | Monoamiinin takaisinoton estäjä | |
| BR0115301A (pt) | Uso de um inibidor seletivo da recaptação de norepinefrina | |
| AR038898A1 (es) | Composiciones para el tratamiento del cabello | |
| AR047550A1 (es) | Tratamiento de la depresion y otros trastornos afectivos | |
| AR031404A1 (es) | Una composicion y metodo de aplicacion | |
| CR7795A (es) | Tetralinos e indanes sustitutos |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |