AR033444A1 - Forma solida de dosificacion util para la administracion oral de un compuesto activo de nicotina, a traves de la mucosa y uso de un compuesto activo de nicotina para prepararla - Google Patents
Forma solida de dosificacion util para la administracion oral de un compuesto activo de nicotina, a traves de la mucosa y uso de un compuesto activo de nicotina para prepararlaInfo
- Publication number
- AR033444A1 AR033444A1 ARP020101068A ARP020101068A AR033444A1 AR 033444 A1 AR033444 A1 AR 033444A1 AR P020101068 A ARP020101068 A AR P020101068A AR P020101068 A ARP020101068 A AR P020101068A AR 033444 A1 AR033444 A1 AR 033444A1
- Authority
- AR
- Argentina
- Prior art keywords
- dosage form
- nicotine
- nicotine compound
- active
- active nicotine
- Prior art date
Links
- 229960002715 nicotine Drugs 0.000 title abstract 9
- SNICXCGAKADSCV-UHFFFAOYSA-N nicotine Natural products CN1CCCC1C1=CC=CN=C1 SNICXCGAKADSCV-UHFFFAOYSA-N 0.000 title abstract 9
- -1 NICOTINE COMPOUND Chemical class 0.000 title abstract 7
- 239000007909 solid dosage form Substances 0.000 title 1
- SNICXCGAKADSCV-JTQLQIEISA-N (-)-Nicotine Chemical compound CN1CCC[C@H]1C1=CC=CN=C1 SNICXCGAKADSCV-JTQLQIEISA-N 0.000 abstract 3
- 239000002552 dosage form Substances 0.000 abstract 3
- SERLAGPUMNYUCK-DCUALPFSSA-N 1-O-alpha-D-glucopyranosyl-D-mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O SERLAGPUMNYUCK-DCUALPFSSA-N 0.000 abstract 2
- SERLAGPUMNYUCK-YJOKQAJESA-N 6-O-alpha-D-glucopyranosyl-D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O SERLAGPUMNYUCK-YJOKQAJESA-N 0.000 abstract 2
- 241000208125 Nicotiana Species 0.000 abstract 2
- 235000002637 Nicotiana tabacum Nutrition 0.000 abstract 2
- 206010057852 Nicotine dependence Diseases 0.000 abstract 2
- 235000010439 isomalt Nutrition 0.000 abstract 2
- 239000006186 oral dosage form Substances 0.000 abstract 2
- 239000007787 solid Substances 0.000 abstract 2
- 150000005846 sugar alcohols Chemical class 0.000 abstract 2
- 235000019788 craving Nutrition 0.000 abstract 1
- 239000011159 matrix material Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 210000004877 mucosa Anatomy 0.000 abstract 1
- 210000002381 plasma Anatomy 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/465—Nicotine; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Addiction (AREA)
- Neurosurgery (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Psychiatry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US27860601P | 2001-03-26 | 2001-03-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR033444A1 true AR033444A1 (es) | 2003-12-17 |
Family
ID=23065632
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP020101068A AR033444A1 (es) | 2001-03-26 | 2002-03-22 | Forma solida de dosificacion util para la administracion oral de un compuesto activo de nicotina, a traves de la mucosa y uso de un compuesto activo de nicotina para prepararla |
Country Status (11)
| Country | Link |
|---|---|
| EP (1) | EP1372392A4 (enExample) |
| JP (1) | JP2004525928A (enExample) |
| CN (2) | CN101301275A (enExample) |
| AR (1) | AR033444A1 (enExample) |
| AU (1) | AU2002252470B2 (enExample) |
| BR (1) | BR0208382A (enExample) |
| CA (1) | CA2440713A1 (enExample) |
| MX (1) | MXPA03008762A (enExample) |
| NZ (1) | NZ528167A (enExample) |
| PL (1) | PL364621A1 (enExample) |
| WO (1) | WO2002076211A1 (enExample) |
Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040253307A1 (en) * | 2003-02-04 | 2004-12-16 | Brian Hague | Sugar-free oral transmucosal solid dosage forms and uses thereof |
| US9119846B2 (en) | 2003-04-29 | 2015-09-01 | Neurim Pharmaceuticals (1991) Ltd. | Method and composition for enhancing cognition in alzheimer's patients |
| IL155666A (en) | 2003-04-29 | 2013-12-31 | Neurim Pharma 1991 | Insomnia treatment |
| PT2446881E (pt) * | 2003-07-24 | 2014-06-11 | Glaxosmithkline Llc | Películas de dissolução oral |
| GB0320854D0 (en) | 2003-09-05 | 2003-10-08 | Arrow No 7 Ltd | Buccal drug delivery |
| US20070191815A1 (en) | 2004-09-13 | 2007-08-16 | Chrono Therapeutics, Inc. | Biosynchronous transdermal drug delivery |
| US8627828B2 (en) | 2003-11-07 | 2014-01-14 | U.S. Smokeless Tobacco Company Llc | Tobacco compositions |
| BRPI0415741B1 (pt) | 2003-11-07 | 2013-07-23 | composições de tabaco e métodos de fabricação de uma composição de tabaco | |
| BRPI0513465B1 (pt) * | 2004-08-11 | 2015-08-11 | Intercontinental Great Brands Llc | Composições orais, artigo comestível, composições para balas e goma de mascar, métodos para preparação do referido artigo e para fornercer sensação às áreas receptoras orais |
| US8252321B2 (en) | 2004-09-13 | 2012-08-28 | Chrono Therapeutics, Inc. | Biosynchronous transdermal drug delivery for longevity, anti-aging, fatigue management, obesity, weight loss, weight management, delivery of nutraceuticals, and the treatment of hyperglycemia, alzheimer's disease, sleep disorders, parkinson's disease, aids, epilepsy, attention deficit disorder, nicotine addiction, cancer, headache and pain control, asthma, angina, hypertension, depression, cold, flu and the like |
| BRPI0719428A2 (pt) * | 2006-12-01 | 2014-02-25 | Cima Labs Inc | Forma de dosagem transmucosal oral sólida, método para tratar dependência de nicotina em um receptor que deseja tal tratamento, sistema de distribuição de nicotina transmucosal oral, e, método de substituíção de nicotina. |
| GB2468424B (en) * | 2007-04-02 | 2011-11-09 | Parkinson S Inst | Methods and compositions for reduction of side effects of therapeutic treatments |
| EP1977746B8 (en) * | 2007-04-02 | 2014-09-24 | Parkinson's Institute | Methods and compositions for reduction of side effects of therapeutic treatments |
| DE102008012015A1 (de) * | 2008-03-01 | 2009-09-10 | Südzucker AG Mannheim/Ochsenfurt | Verbesserte Isomalt-haltige Komprimate und Verfahren zu ihrer Herstellung |
| EP2536409A4 (en) * | 2010-02-18 | 2013-07-17 | Jatin Vasant Thakkar | NICOTINE-CONTAINING SOFT GELATINETABLETTEN |
| US20110274628A1 (en) * | 2010-05-07 | 2011-11-10 | Borschke August J | Nicotine-containing pharmaceutical compositions |
| UA112974C2 (uk) | 2010-09-16 | 2016-11-25 | Джеі. Бі. Кемікалс Енд Фармасьютікалс Лімітид | Нікотиновмісна композиція (варіанти) |
| US20130017259A1 (en) | 2011-07-06 | 2013-01-17 | The Parkinson's Institute | Compositions and Methods for Treatment of Symptoms in Parkinson's Disease Patients |
| US9629392B2 (en) | 2011-09-22 | 2017-04-25 | R.J. Reynolds Tobacco Company | Translucent smokeless tobacco product |
| US9474303B2 (en) | 2011-09-22 | 2016-10-25 | R.J. Reynolds Tobacco Company | Translucent smokeless tobacco product |
| US20130078307A1 (en) | 2011-09-22 | 2013-03-28 | Niconovum Usa, Inc. | Nicotine-containing pharmaceutical composition |
| US9084439B2 (en) | 2011-09-22 | 2015-07-21 | R.J. Reynolds Tobacco Company | Translucent smokeless tobacco product |
| US9907748B2 (en) | 2011-10-21 | 2018-03-06 | Niconovum Usa, Inc. | Excipients for nicotine-containing therapeutic compositions |
| US9044035B2 (en) | 2012-04-17 | 2015-06-02 | R.J. Reynolds Tobacco Company | Remelted ingestible products |
| US10105487B2 (en) | 2013-01-24 | 2018-10-23 | Chrono Therapeutics Inc. | Optimized bio-synchronous bioactive agent delivery system |
| AR096223A1 (es) * | 2013-05-10 | 2015-12-16 | Glaxosmithkline Llc | Pastilla de nicotina para administración oral |
| CN104132895B (zh) * | 2014-07-08 | 2017-08-25 | 国家烟草质量监督检验中心 | 适用于连续流动法测定烟草及烟草制品中总植物碱的缓冲体系 |
| JP2018511355A (ja) | 2015-01-28 | 2018-04-26 | クロノ セラピューティクス インコーポレイテッドＣｈｒｏｎｏ Ｔｈｅｒａｐｅｕｔｉｃｓ Ｉｎｃ． | 薬剤送達方法及びシステム |
| AU2016228779A1 (en) | 2015-03-12 | 2017-09-07 | Chrono Therapeutics Inc. | Craving input and support system |
| WO2018129304A1 (en) | 2017-01-06 | 2018-07-12 | Chrono Therapeutics Inc. | Transdermal drug delivery devices and methods |
| SE541358C2 (en) * | 2017-05-30 | 2019-08-13 | Enorama Pharma Ab | Nicotine-containing chewing gum compositions |
| AU2019279884B2 (en) | 2018-05-29 | 2025-01-30 | Morningside Venture Investments Limited | Drug delivery methods and systems |
| JP2022507660A (ja) | 2018-11-16 | 2022-01-18 | モーニングサイド ベンチャー インベストメンツ リミテッド | 温度によって調節される経皮薬剤送達システム |
| MX2021014975A (es) * | 2019-06-07 | 2022-01-24 | Philip Morris Products Sa | Producto oral en bolsitas. |
| CN115003281A (zh) * | 2020-01-15 | 2022-09-02 | 麦克内尔股份公司 | 锭剂 |
| USD1081739S1 (en) | 2021-04-06 | 2025-07-01 | Altria Client Services Llc | Die for gum forming |
| US20220313678A1 (en) * | 2021-04-06 | 2022-10-06 | Altria Client Services Llc | Spray dried nicotine for inclusion in oral products |
| US20220313614A1 (en) * | 2021-04-06 | 2022-10-06 | Altria Client Services Llc | Encapsulated nicotine granules and methods of preparation thereof |
| US12295412B2 (en) | 2022-01-28 | 2025-05-13 | Altria Client Services Llc | Oral pouch product |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9310412D0 (en) * | 1993-05-20 | 1993-07-07 | Danbiosyst Uk | Nasal nicotine system |
| US5549906A (en) * | 1993-07-26 | 1996-08-27 | Pharmacia Ab | Nicotine lozenge and therapeutic method for smoking cessation |
| US5362496A (en) * | 1993-08-04 | 1994-11-08 | Pharmetrix Corporation | Method and therapeutic system for smoking cessation |
| DE19536394A1 (de) * | 1995-09-29 | 1997-04-03 | Basf Ag | Feste Arzneiformen, erhältlich durch Extrusion einer Isomalt enthaltenden Polymer-Wirkstoff-Schmelze |
| DE19639342C2 (de) * | 1996-09-25 | 1998-07-16 | Suedzucker Ag | Kaugummi, enthaltend ein Süßungsmittel |
| US6322806B1 (en) * | 1999-04-06 | 2001-11-27 | Wm. Wrigley Jr. Company | Over-coated chewing gum formulations including tableted center |
-
2002
- 2002-03-22 NZ NZ528167A patent/NZ528167A/en not_active IP Right Cessation
- 2002-03-22 CN CNA2008101253651A patent/CN101301275A/zh active Pending
- 2002-03-22 AU AU2002252470A patent/AU2002252470B2/en not_active Ceased
- 2002-03-22 WO PCT/US2002/008914 patent/WO2002076211A1/en not_active Ceased
- 2002-03-22 CA CA002440713A patent/CA2440713A1/en not_active Abandoned
- 2002-03-22 PL PL02364621A patent/PL364621A1/xx not_active Application Discontinuation
- 2002-03-22 EP EP02721544A patent/EP1372392A4/en not_active Withdrawn
- 2002-03-22 BR BR0208382-5A patent/BR0208382A/pt not_active IP Right Cessation
- 2002-03-22 MX MXPA03008762A patent/MXPA03008762A/es active IP Right Grant
- 2002-03-22 CN CNA028073339A patent/CN1553771A/zh active Pending
- 2002-03-22 AR ARP020101068A patent/AR033444A1/es unknown
- 2002-03-22 JP JP2002574739A patent/JP2004525928A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| NZ528167A (en) | 2005-04-29 |
| CN101301275A (zh) | 2008-11-12 |
| AU2002252470B2 (en) | 2008-05-22 |
| MXPA03008762A (es) | 2004-02-18 |
| BR0208382A (pt) | 2004-06-15 |
| WO2002076211A1 (en) | 2002-10-03 |
| CN1553771A (zh) | 2004-12-08 |
| EP1372392A1 (en) | 2004-01-02 |
| EP1372392A4 (en) | 2004-06-23 |
| PL364621A1 (en) | 2004-12-13 |
| JP2004525928A (ja) | 2004-08-26 |
| CA2440713A1 (en) | 2002-10-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |