AR029642A1 - Una molecula de adn aislada que codifica un ligando denominado fhm que pertenece a la familia de supergenes de ligandos de tnf, polipeptidos de fhm, anticuerpos que conjugan fhm, materiales que integran dicha molecula y metodos de uso de dichas moleculas, metodos y compuestos farmaceuticos, metodos - Google Patents
Una molecula de adn aislada que codifica un ligando denominado fhm que pertenece a la familia de supergenes de ligandos de tnf, polipeptidos de fhm, anticuerpos que conjugan fhm, materiales que integran dicha molecula y metodos de uso de dichas moleculas, metodos y compuestos farmaceuticos, metodosInfo
- Publication number
- AR029642A1 AR029642A1 ARP000104020A ARP000104020A AR029642A1 AR 029642 A1 AR029642 A1 AR 029642A1 AR P000104020 A ARP000104020 A AR P000104020A AR P000104020 A ARP000104020 A AR P000104020A AR 029642 A1 AR029642 A1 AR 029642A1
- Authority
- AR
- Argentina
- Prior art keywords
- fhm
- methods
- metolosmosuas
- supergenes
- polypeptides
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 5
- 229920001184 polypeptide Polymers 0.000 title abstract 3
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 3
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 3
- 239000000463 material Substances 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 230000002159 abnormal effect Effects 0.000 abstract 4
- 201000010099 disease Diseases 0.000 abstract 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 2
- 239000003446 ligand Substances 0.000 abstract 2
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- 238000003745 diagnosis Methods 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 238000010188 recombinant method Methods 0.000 abstract 1
- 239000013598 vector Substances 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70575—NGF/TNF-superfamily, e.g. CD70, CD95L, CD153, CD154
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2799/00—Uses of viruses
- C12N2799/02—Uses of viruses as vector
- C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Oncology (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Communicable Diseases (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Rheumatology (AREA)
- Cell Biology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Peptides Or Proteins (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Virology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pain & Pain Management (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Un nuevo ligando de receptor, designado Fhm, que pertenece a la familia de los supergenes de los ligandos de TNF y las moléculas de ácido nucleico que los codifica. También se ocupa de vectores, células huéspedes, anticuerpos anti-Fhm y métodos recombinantes para la produccion de polipéptidos Fhm. También proporciona el uso del polipéptido Fhm recombinante para identificar parejas/receptores aglutinantes putativas. Adicionalmente, el invento provee métodos y reactivos para el diagnostico de enfermedades asociadas con Fhm anormal o la expresion anormal de su receptor putativo; y métodos y compuestos farmacéuticos para el tratamiento de enfermedades asociadas con Fhm anormal o la expresion anormal de Fhm y/o su receptor. Así mismo divulga compuestos farmacéuticos para el uso en el tratamiento de estas enfermedades.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US14729499P | 1999-08-04 | 1999-08-04 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR029642A1 true AR029642A1 (es) | 2003-07-10 |
Family
ID=22521006
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP000104020A AR029642A1 (es) | 1999-08-04 | 2000-08-04 | Una molecula de adn aislada que codifica un ligando denominado fhm que pertenece a la familia de supergenes de ligandos de tnf, polipeptidos de fhm, anticuerpos que conjugan fhm, materiales que integran dicha molecula y metodos de uso de dichas moleculas, metodos y compuestos farmaceuticos, metodos |
Country Status (9)
Country | Link |
---|---|
US (4) | US6521422B1 (es) |
EP (1) | EP1210435A1 (es) |
JP (1) | JP2003506088A (es) |
AR (1) | AR029642A1 (es) |
AU (1) | AU783682B2 (es) |
CA (1) | CA2381284A1 (es) |
MX (1) | MXPA02001264A (es) |
TW (1) | TW200716746A (es) |
WO (1) | WO2001011050A1 (es) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6599719B2 (en) * | 1994-11-07 | 2003-07-29 | Human Genome Sciences, Inc. | Nucleic acid molecules encoding tumor necrosis factor-gamma-alpha |
US20030203435A1 (en) * | 1998-04-30 | 2003-10-30 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US20060148711A1 (en) * | 1999-05-14 | 2006-07-06 | Arbor Vita Corporation | Molecular interactions in neurons |
JP2003506088A (ja) * | 1999-08-04 | 2003-02-18 | アムジェン インコーポレーテッド | TNFリガンドスーパー遺伝子ファミリーの新規のメンバーであるFhm |
AU2003253381A1 (en) * | 2002-08-06 | 2004-02-25 | Aplagen Gmbh | Binding molecules |
US9453251B2 (en) | 2002-10-08 | 2016-09-27 | Pfenex Inc. | Expression of mammalian proteins in Pseudomonas fluorescens |
JP2005173484A (ja) * | 2003-12-15 | 2005-06-30 | Canon Inc | 画像形成装置及びプロセスカートリッジ |
EP2412816B1 (en) | 2004-07-26 | 2014-12-03 | Pfenex Inc. | Process for improved protein expression by strain engineering |
US7292198B2 (en) * | 2004-08-18 | 2007-11-06 | Ruckus Wireless, Inc. | System and method for an omnidirectional planar antenna apparatus with selectable elements |
US7193562B2 (en) | 2004-11-22 | 2007-03-20 | Ruckus Wireless, Inc. | Circuit board having a peripheral antenna apparatus with selectable antenna elements |
US7358912B1 (en) | 2005-06-24 | 2008-04-15 | Ruckus Wireless, Inc. | Coverage antenna apparatus with selectable horizontal and vertical polarization elements |
US7893882B2 (en) | 2007-01-08 | 2011-02-22 | Ruckus Wireless, Inc. | Pattern shaping of RF emission patterns |
MX2009011523A (es) | 2007-04-27 | 2009-11-09 | Dow Global Technologies Inc | Metodo para clasificar rapidamente huespedes microbianos para identificar ciertas cepas con rendimiento y/o calidad mejorados en la expresion de proteinas heterologas. |
US9580719B2 (en) | 2007-04-27 | 2017-02-28 | Pfenex, Inc. | Method for rapidly screening microbial hosts to identify certain strains with improved yield and/or quality in the expression of heterologous proteins |
US8217843B2 (en) | 2009-03-13 | 2012-07-10 | Ruckus Wireless, Inc. | Adjustment of radiation patterns utilizing a position sensor |
JO3375B1 (ar) | 2010-11-08 | 2019-03-13 | Regeneron Pharma | أجسام مضادة بشرية للجين a1 الشبيه بعامل النخر الورمي (tl1a) |
US8756668B2 (en) | 2012-02-09 | 2014-06-17 | Ruckus Wireless, Inc. | Dynamic PSK for hotspots |
US10186750B2 (en) | 2012-02-14 | 2019-01-22 | Arris Enterprises Llc | Radio frequency antenna array with spacing element |
US9634403B2 (en) | 2012-02-14 | 2017-04-25 | Ruckus Wireless, Inc. | Radio frequency emission pattern shaping |
US9092610B2 (en) | 2012-04-04 | 2015-07-28 | Ruckus Wireless, Inc. | Key assignment for a brand |
KR102366076B1 (ko) | 2013-11-13 | 2022-02-21 | 화이자 인코포레이티드 | 종양 괴사 인자-유사 리간드 1a 특이적 항체 및 그의 조성물 및 용도 |
CR20180365A (es) | 2015-12-16 | 2018-09-28 | Amgen Inc | PROTEÍNAS DE UNIÓN AL ANTÍGENO BISPECÍFICO DE ANTI-TL1A/ANTI-TNF-a Y SUS USOS |
Family Cites Families (43)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL107267A (en) | 1993-10-12 | 2009-07-20 | Yeda Res & Dev | Ligand to a member of the tnf/ngf receptor family |
US5605690A (en) | 1989-09-05 | 1997-02-25 | Immunex Corporation | Methods of lowering active TNF-α levels in mammals using tumor necrosis factor receptor |
US6541610B1 (en) | 1989-09-05 | 2003-04-01 | Immunex Corporation | Fusion proteins comprising tumor necrosis factor receptor |
NZ237669A (en) | 1990-04-13 | 1992-08-26 | Res Dev Foundation | T-cell proteins expressed in t-cell development and their preparation |
NZ251820A (en) | 1992-03-30 | 1996-07-26 | Immunex Corp | Fusion proteins with tnf-r (tumour necrosis factor-receptor) peptide linked to another tnf-r or an il-1r (interleukin-1-receptor) peptide |
AU670125B2 (en) | 1992-09-15 | 1996-07-04 | Immunex Corporation | Method of treating tnf-dependent inflammation using tumor necrosis factor antagonists |
US5489743A (en) | 1993-01-19 | 1996-02-06 | Amgen Inc. | Transgenic animal models for thrombocytopenia |
US20030198640A1 (en) | 1994-11-07 | 2003-10-23 | Human Genome Sciences, Inc. | Methods and compositions for treating inflammatory bowel diseases relating to human tumor necrosis factor-gamma-beta |
US20030129189A1 (en) | 1994-11-07 | 2003-07-10 | Guo-Liang Yu | Tumor necrosis factor-gamma |
US6824767B2 (en) * | 1994-11-07 | 2004-11-30 | Human Genome Sciences, Inc. | Tumor necrosis factor-gamma |
KR100507431B1 (ko) | 1994-11-07 | 2005-12-21 | 휴먼 게놈 사이언시즈, 인코포레이티드 | 종양괴사인자-γ |
US6599719B2 (en) | 1994-11-07 | 2003-07-29 | Human Genome Sciences, Inc. | Nucleic acid molecules encoding tumor necrosis factor-gamma-alpha |
US7597886B2 (en) | 1994-11-07 | 2009-10-06 | Human Genome Sciences, Inc. | Tumor necrosis factor-gamma |
US5843789A (en) | 1995-05-16 | 1998-12-01 | Neomecs Incorporated | Method of analysis of genomic biopolymer and porous materials for genomic analyses |
RU97121687A (ru) | 1995-05-26 | 2005-01-20 | Синджента Лимитед (Gb) | Ген-переключатель, представляющий ген рецептора экдизона |
US20040013664A1 (en) | 1997-01-14 | 2004-01-22 | Gentz Reiner L. | Tumor necrosis factor receptors 6 alpha & 6 beta |
US7285267B2 (en) | 1997-01-14 | 2007-10-23 | Human Genome Sciences, Inc. | Tumor necrosis factor receptors 6α & 6β |
US8003386B1 (en) | 1997-01-14 | 2011-08-23 | Human Genome Sciences, Inc. | Tumor necrosis factor receptors 6α and 6β |
US5863769A (en) | 1997-01-28 | 1999-01-26 | Smithkline Beecham Corporation | DNA encoding interleukin-1 receptor antagonist (IL-1raβ) |
US5885800A (en) * | 1997-02-04 | 1999-03-23 | Smithkline Beecham Corporation | DNA encoding tumor necrosis related receptor, TR4 |
US6072047A (en) | 1997-02-13 | 2000-06-06 | Immunex Corporation | Receptor that binds trail |
TW562807B (en) | 1997-04-01 | 2003-11-21 | Chugai Pharmaceutical Co Ltd | Novel secretory membrane protein |
AU8395798A (en) | 1997-07-15 | 1999-02-10 | Immunex Corporation | Trail receptor |
WO1999004001A1 (en) | 1997-07-21 | 1999-01-28 | Zymogenetics, Inc. | Tumor necrosis factor receptor ztnfr-5 |
AU751396B2 (en) | 1997-08-04 | 2002-08-15 | Millennium Pharmaceuticals, Inc. | Novel molecules of the Tango-77 related protein family and uses thereof |
CA2299619A1 (en) | 1997-08-06 | 1999-02-18 | Regeneron Pharmaceuticals, Inc. | Human orphan receptor ntr-1 |
WO1999011791A2 (en) | 1997-09-05 | 1999-03-11 | University Of Washington | Tumor necrosis factor family receptors and ligands, encoding nucleic acids and related binding agents |
IL134578A0 (en) | 1997-09-18 | 2001-04-30 | Genentech Inc | DcR3 POLYPEPTIDE, A TNFR HOMOLOG |
WO1999020758A1 (en) | 1997-10-21 | 1999-04-29 | Human Genome Sciences, Inc. | Human tumor necrosis factor receptor-like proteins tr11, tr11sv1, and tr11sv2 |
US20020111325A1 (en) | 1997-11-03 | 2002-08-15 | Human Genome Sciences, Inc. | VEGI, an inhibitor of angiogenesis and tumor growth |
CA2309541C (en) * | 1997-11-03 | 2011-01-11 | Human Genome Sciences, Inc. | Vegi, an inhibitor of angiogenesis and tumor growth |
WO1999026977A1 (en) | 1997-11-24 | 1999-06-03 | Biogen, Inc. | Novel receptors opg-2 |
EP1037908A2 (en) | 1997-12-16 | 2000-09-27 | Incyte Pharmaceuticals, Inc. | Human tumor necrosis factor-r2-like proteins |
NZ505881A (en) | 1998-01-09 | 2003-05-30 | Immunex Corp | IL-1 delta DNA and polypeptides |
DE19809978A1 (de) | 1998-03-09 | 1999-09-16 | Basf Ag | Neuer Rezeptor aus der menschlichen Lunge |
IL138626A0 (en) | 1998-03-30 | 2001-10-31 | Lilly Co Eli | Therapeutic applications of mature flint (mflint) polypeptides or opg3, a member of the receptor superfamily |
CA2326066A1 (en) | 1998-04-03 | 1999-10-14 | Hyseq, Inc. | A interleukin-1 receptor antagonist and uses thereof |
US6274339B1 (en) * | 1999-02-05 | 2001-08-14 | Millennium Pharmaceuticals, Inc. | Methods and compositions for the diagnosis and treatment of body weight disorders, including obesity |
AU6280999A (en) | 1998-09-30 | 2000-04-17 | Millennium Pharmaceuticals, Inc. | Novel secreted immunomodulatory proteins and uses thereof |
US6627199B1 (en) | 1999-07-09 | 2003-09-30 | Amgen Inc | Isolation, identification and characterization of tmst2, a novel member of the TNF-receptor supergene family |
US20030096355A1 (en) | 1999-07-09 | 2003-05-22 | Ke Zhang | Isolation, identification and characterization of ymkz5, a novel member of the TNF-receptor supergene family |
JP2003506088A (ja) * | 1999-08-04 | 2003-02-18 | アムジェン インコーポレーテッド | TNFリガンドスーパー遺伝子ファミリーの新規のメンバーであるFhm |
US6569685B1 (en) * | 1999-10-05 | 2003-05-27 | The Molecular Sciences Institute, Inc. | Protein fingerprint system and related methods |
-
2000
- 2000-08-03 JP JP2001515835A patent/JP2003506088A/ja not_active Withdrawn
- 2000-08-03 WO PCT/US2000/021284 patent/WO2001011050A1/en active IP Right Grant
- 2000-08-03 EP EP00982731A patent/EP1210435A1/en not_active Withdrawn
- 2000-08-03 MX MXPA02001264A patent/MXPA02001264A/es not_active Application Discontinuation
- 2000-08-03 CA CA002381284A patent/CA2381284A1/en not_active Abandoned
- 2000-08-03 US US09/632,287 patent/US6521422B1/en not_active Expired - Fee Related
- 2000-08-03 AU AU28071/01A patent/AU783682B2/en not_active Ceased
- 2000-08-04 TW TW095131624A patent/TW200716746A/zh unknown
- 2000-08-04 AR ARP000104020A patent/AR029642A1/es unknown
-
2002
- 2002-11-01 US US10/286,696 patent/US6852839B2/en not_active Expired - Fee Related
-
2004
- 2004-07-13 US US10/890,368 patent/US7544519B2/en not_active Expired - Fee Related
- 2004-07-13 US US10/889,948 patent/US20040265913A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
US20030129706A1 (en) | 2003-07-10 |
US20040265913A1 (en) | 2004-12-30 |
CA2381284A1 (en) | 2001-02-15 |
US6852839B2 (en) | 2005-02-08 |
TW200716746A (en) | 2007-05-01 |
MXPA02001264A (es) | 2002-07-22 |
US7544519B2 (en) | 2009-06-09 |
US6521422B1 (en) | 2003-02-18 |
EP1210435A1 (en) | 2002-06-05 |
AU2807101A (en) | 2001-03-05 |
US20040248324A1 (en) | 2004-12-09 |
AU783682B2 (en) | 2005-11-24 |
JP2003506088A (ja) | 2003-02-18 |
WO2001011050A1 (en) | 2001-02-15 |
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