AR028281A1 - Derivados de 2-(arilalquilamino) pirimidona y derivados de 2-(heteroaroarilalquilamino) pirimidona - Google Patents

Derivados de 2-(arilalquilamino) pirimidona y derivados de 2-(heteroaroarilalquilamino) pirimidona

Info

Publication number
AR028281A1
AR028281A1 ARP010101373A ARP010101373A AR028281A1 AR 028281 A1 AR028281 A1 AR 028281A1 AR P010101373 A ARP010101373 A AR P010101373A AR P010101373 A ARP010101373 A AR P010101373A AR 028281 A1 AR028281 A1 AR 028281A1
Authority
AR
Argentina
Prior art keywords
pirimidona
derivatives
heteroaroarilalquilamino
arilalquilamino
Prior art date
Application number
ARP010101373A
Other languages
English (en)
Original Assignee
Sanofi Synthelabo
Mitsubishi Tokyo Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from EP00400805A external-priority patent/EP1136099A1/en
Priority claimed from JP2000081938A external-priority patent/JP2001270884A/ja
Priority claimed from EP00400806A external-priority patent/EP1136491A1/en
Priority claimed from EP00400804A external-priority patent/EP1136484A1/en
Application filed by Sanofi Synthelabo, Mitsubishi Tokyo Pharm Inc filed Critical Sanofi Synthelabo
Publication of AR028281A1 publication Critical patent/AR028281A1/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ARP010101373A 2000-03-23 2001-03-23 Derivados de 2-(arilalquilamino) pirimidona y derivados de 2-(heteroaroarilalquilamino) pirimidona AR028281A1 (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP00400805A EP1136099A1 (en) 2000-03-23 2000-03-23 2-(Indolylalkylamino)pyrimidone derivatives as GSK3beta inhibitors
JP2000081938A JP2001270884A (ja) 2000-03-23 2000-03-23 ピリミドン誘導体
EP00400806A EP1136491A1 (en) 2000-03-23 2000-03-23 2-[(Heteroaryl)alkylamino]pyrimidone derivatives
EP00400804A EP1136484A1 (en) 2000-03-23 2000-03-23 2-(Arylalkylamino)pyrimidone derivatives

Publications (1)

Publication Number Publication Date
AR028281A1 true AR028281A1 (es) 2003-04-30

Family

ID=27440051

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP010101373A AR028281A1 (es) 2000-03-23 2001-03-23 Derivados de 2-(arilalquilamino) pirimidona y derivados de 2-(heteroaroarilalquilamino) pirimidona

Country Status (3)

Country Link
AR (1) AR028281A1 (es)
AU (1) AU2001248365A1 (es)
WO (1) WO2001070727A1 (es)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE284712T1 (de) 2000-04-26 2005-01-15 Eisai Co Ltd Medizinische zusammensetzungen zur förderung der aktivierung der eingeweide
TWI335221B (en) * 2001-09-27 2011-01-01 Alcon Inc Inhibtors of glycogen synthase kinase-3 (gsk-3) for treating glaucoma
TWI301834B (en) * 2001-10-22 2008-10-11 Eisai R&D Man Co Ltd Pyrimidone compound and pharmaceutical composition including the same
TWI330183B (es) 2001-10-22 2010-09-11 Eisai R&D Man Co Ltd
US20050203059A1 (en) * 2002-03-01 2005-09-15 Harrison Stephen D. Methods and compositions for treatment of ischemia
EP2221054A1 (en) 2002-04-30 2010-08-25 Alcon, Inc. CDK inhibitors for lowering intraocular pressure
EP1616568A3 (en) * 2002-04-30 2006-06-21 Alcon, Inc GSK-3 inhibitors and CDK inhibitors as anti-glaucoma agents
JP2006506383A (ja) 2002-10-21 2006-02-23 カイロン コーポレイション グリコーゲンシンターゼキナーゼ3のインヒビター
WO2005076854A2 (en) * 2004-02-04 2005-08-25 Smithkline Beecham Corporation Pyrimidinone compounds useful as kinase inhibitors
MX2007008326A (es) 2005-01-07 2008-01-16 Univ Emory Antagonistas de cxcr4 para el tratamiento de una infeccion por vih.
EP2258359A3 (en) 2005-08-26 2011-04-06 Braincells, Inc. Neurogenesis by muscarinic receptor modulation with sabcomelin
JP2009506069A (ja) 2005-08-26 2009-02-12 ブレインセルス,インコーポレイティド ムスカリン性受容体調節による神経発生
AU2006304787A1 (en) 2005-10-21 2007-04-26 Braincells, Inc. Modulation of neurogenesis by PDE inhibition
CA2625210A1 (en) 2005-10-31 2007-05-10 Braincells, Inc. Gaba receptor mediated modulation of neurogenesis
US20100216734A1 (en) 2006-03-08 2010-08-26 Braincells, Inc. Modulation of neurogenesis by nootropic agents
AU2007249399A1 (en) 2006-05-09 2007-11-22 Braincells, Inc. Neurogenesis by modulating angiotensin
WO2008008854A2 (en) 2006-07-11 2008-01-17 Emory University Cxcr4 antagonists including diazine and triazine structures for the treatment of medical disorders
AU2007275686B2 (en) * 2006-07-18 2013-10-31 University Of Rochester Thiadiazolidinone derivatives
EP2057141B1 (en) * 2006-08-23 2011-10-26 Pfizer Products Inc. Pyrimidone compounds as gsk-3 inhibitors
US20100184806A1 (en) 2006-09-19 2010-07-22 Braincells, Inc. Modulation of neurogenesis by ppar agents
CA2704199C (en) * 2007-11-01 2016-01-19 Acucela Inc. Amine derivative compounds for treating ophthalmic diseases and disorders
WO2010099217A1 (en) 2009-02-25 2010-09-02 Braincells, Inc. Modulation of neurogenesis using d-cycloserine combinations

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW520362B (en) * 1996-12-05 2003-02-11 Amgen Inc Substituted pyrimidine compounds and pharmaceutical composition comprising same

Also Published As

Publication number Publication date
WO2001070727A1 (en) 2001-09-27
AU2001248365A1 (en) 2001-10-03

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