AR025572A1 - COPOLIMERO THAT HAS AN ELONGATION OF AT LEAST 150%, AN OPHTHALMIC LENS THAT UNDERSTANDS IT AND INTRAOCULAR LENSES - Google Patents

COPOLIMERO THAT HAS AN ELONGATION OF AT LEAST 150%, AN OPHTHALMIC LENS THAT UNDERSTANDS IT AND INTRAOCULAR LENSES

Info

Publication number
AR025572A1
AR025572A1 ARP000104654A ARP000104654A AR025572A1 AR 025572 A1 AR025572 A1 AR 025572A1 AR P000104654 A ARP000104654 A AR P000104654A AR P000104654 A ARP000104654 A AR P000104654A AR 025572 A1 AR025572 A1 AR 025572A1
Authority
AR
Argentina
Prior art keywords
monomer
amount
elongation
ophthalmic lens
intraocular lenses
Prior art date
Application number
ARP000104654A
Other languages
Spanish (es)
Original Assignee
Alcon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcon Inc filed Critical Alcon Inc
Publication of AR025572A1 publication Critical patent/AR025572A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
    • C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
    • C08F220/10—Esters
    • C08F220/26—Esters containing oxygen in addition to the carboxy oxygen
    • C08F220/30—Esters containing oxygen in addition to the carboxy oxygen containing aromatic rings in the alcohol moiety
    • C08F220/301—Esters containing oxygen in addition to the carboxy oxygen containing aromatic rings in the alcohol moiety and one oxygen in the alcohol moiety
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
    • A61F2/16—Intraocular lenses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/16—Macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
    • C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
    • C08F220/10—Esters
    • C08F220/26—Esters containing oxygen in addition to the carboxy oxygen
    • C08F220/30—Esters containing oxygen in addition to the carboxy oxygen containing aromatic rings in the alcohol moiety
    • C08F220/302—Esters containing oxygen in addition to the carboxy oxygen containing aromatic rings in the alcohol moiety and two or more oxygen atoms in the alcohol moiety
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B1/00—Optical elements characterised by the material of which they are made; Optical coatings for optical elements
    • G02B1/04—Optical elements characterised by the material of which they are made; Optical coatings for optical elements made of organic materials, e.g. plastics
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B1/00—Optical elements characterised by the material of which they are made; Optical coatings for optical elements
    • G02B1/04—Optical elements characterised by the material of which they are made; Optical coatings for optical elements made of organic materials, e.g. plastics
    • G02B1/041—Lenses
    • G02B1/043—Contact lenses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/16—Materials or treatment for tissue regeneration for reconstruction of eye parts, e.g. intraocular lens, cornea

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Ophthalmology & Optometry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Optics & Photonics (AREA)
  • Engineering & Computer Science (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Cardiology (AREA)
  • General Physics & Mathematics (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Materials For Medical Uses (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Eyeglasses (AREA)
  • Prostheses (AREA)
  • Manufacture Of Macromolecular Shaped Articles (AREA)
  • Compositions Of Macromolecular Compounds (AREA)

Abstract

Copolímero que tienen una elongacion de al menos el 150%, que comprende un total de al menos el 90% en peso de dos monomeros principales, donde un monomeroprincipal es un monomero hidrofobico de aril acrílico de la formula: CH2=CX-COO-(CH2)m-Y-(CH2) wAr, donde X es H o CH3; M es 2-6; Y es O o O(CH2CH2O)n; n es1-6; w es 1-6, si m+w menor o igual a 8; y Ar es cualquier anillo aromático que puede estar no sustituido o sustituido con CH3, C2H5, n-C3H7, iso-C3H7, OCH3,C6H11,Cl, Br, C6H5, o CH2C6H5; cuyo homopolímero tiene un contenido de agua en equilibrio del 3% o menos, y el otro monomero principal, presente en unacantidad no mayor a la cantidad del monomero hidrofobico de aril acrílico, es un monomero hidrofílicoque tiene al menos un grupo funcional no saturadoreactivo , cuyo homopolímero tiene un contenido de agua en equilibrio de al menos el 10%, y donde el copolímero además comprende un monomero deentrecruzamiento que tiene una cantidad de gruposetilénicamente nosaturados, que se p ueden polimerizar; una lente oftálmica que lo comprende y lentesintraoculares. Estos materiales, son especialmente utiles como materiales para lentes intraoculares, que contiene dos monomeros principales: unmonomerohidrofobico de aril acrílico y un monomero hidrofílico.Copolymer having an elongation of at least 150%, which comprises a total of at least 90% by weight of two main monomers, where a single-plane is a hydrophobic aryl acrylic monomer of the formula: CH2 = CX-COO- ( CH2) mY- (CH2) wAr, where X is H or CH3; M is 2-6; Y is O or O (CH2CH2O) n; n is 1-6; w is 1-6, if m + w less than or equal to 8; and Ar is any aromatic ring that may be unsubstituted or substituted with CH3, C2H5, n-C3H7, iso-C3H7, OCH3, C6H11, Cl, Br, C6H5, or CH2C6H5; whose homopolymer has an equilibrium water content of 3% or less, and the other main monomer, present in an amount no greater than the amount of the hydrophobic aryl acrylic monomer, is a hydrophilic monomer which has at least one non-saturated reactive functional group, whose Homopolymer has an equilibrium water content of at least 10%, and where the copolymer also comprises a cross-linking monomer having an amount of ethylenically nosaturated groups, which can be polymerized; an ophthalmic lens that comprises it and intraocular lenses. These materials are especially useful as intraocular lens materials, which contains two main monomers: an acrylic aryl acrylic monomer and a hydrophilic monomer.

ARP000104654A 1999-09-07 2000-09-06 COPOLIMERO THAT HAS AN ELONGATION OF AT LEAST 150%, AN OPHTHALMIC LENS THAT UNDERSTANDS IT AND INTRAOCULAR LENSES AR025572A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US15262199P 1999-09-07 1999-09-07

Publications (1)

Publication Number Publication Date
AR025572A1 true AR025572A1 (en) 2002-12-04

Family

ID=22543684

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP000104654A AR025572A1 (en) 1999-09-07 2000-09-06 COPOLIMERO THAT HAS AN ELONGATION OF AT LEAST 150%, AN OPHTHALMIC LENS THAT UNDERSTANDS IT AND INTRAOCULAR LENSES

Country Status (8)

Country Link
EP (1) EP1210381A1 (en)
JP (1) JP2003508605A (en)
CN (1) CN1371394A (en)
AR (1) AR025572A1 (en)
AU (1) AU766397B2 (en)
BR (1) BR0013779A (en)
CA (1) CA2381177A1 (en)
WO (1) WO2001018079A1 (en)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6281319B1 (en) 1999-04-12 2001-08-28 Surgidev Corporation Water plasticized high refractive index polymer for ophthalmic applications
US8247511B2 (en) 1999-04-12 2012-08-21 Advanced Vision Science, Inc. Water plasticized high refractive index polymer for ophthalmic applications
DK1210380T3 (en) * 1999-09-07 2005-05-30 Alcon Inc Foldable ophthalmic and otorhinolaryngological device materials
GB0107540D0 (en) * 2001-03-26 2001-05-16 Contamac Ltd Polymer compositions
PT1521786E (en) 2002-07-16 2008-05-27 Alcon Inc Ophthalmic and otorhinolaryngological device materials
US9114199B2 (en) * 2003-07-31 2015-08-25 Boston Scientific Scimed, Inc. Implantable or insertable medical devices containing acrylic copolymer for controlled delivery of therapeutic agent
US20050070688A1 (en) 2003-09-26 2005-03-31 3M Innovative Properties Company Reactive hydrophilic oligomers
US7384984B2 (en) 2003-12-10 2008-06-10 3M Innovative Properties Company Reactive hydrophilic oligomers
US7074839B2 (en) 2004-03-01 2006-07-11 3M Innovative Properties Company Crosslinkable hydrophilic materials from reactive oligomers having pendent photoinitiator groups
US7446157B2 (en) 2004-12-07 2008-11-04 Key Medical Technologies, Inc. Nanohybrid polymers for ophthalmic applications
US7714039B2 (en) 2006-07-21 2010-05-11 Alcon, Inc. Low-tack ophthalmic and otorhinolaryngological device materials
US8058323B2 (en) 2006-07-21 2011-11-15 Novartis Ag Low-tack ophthalmic and otorhinolaryngological device materials
TWI399228B (en) 2006-07-21 2013-06-21 Alcon Inc Low-tack ophthalmic and otorhinolaryngological device materials
US7790824B2 (en) 2007-07-25 2010-09-07 Alcon, Inc. High refractive index ophthalmic device materials
TWI426932B (en) * 2007-10-05 2014-02-21 Alcon Inc Ophthalmic and otorhinolaryngological device materials
TWI461186B (en) * 2007-10-05 2014-11-21 Alcon Inc Ophthalmic and otorhinolaryngological device materials
FR2930731B1 (en) * 2008-04-30 2014-06-27 Acrylian ACRYLIC POLYMERIC MATERIAL, HYDROPHOBIC FOR INTRAOCULAR LENS
ES2340241B1 (en) * 2008-05-21 2011-04-28 Consejo Superior De Investigaciones Cientificas (Csic) HYDROPHILE ACRYLIC COPOLYMERS DERIVED FROM EUGENOL, PREPARATION, CHARACTERIZATION AND ITS USE AS OPHTHALMIC LENSES.
US9622853B2 (en) 2010-07-05 2017-04-18 Jagrat Natavar DAVE Polymeric composition for ocular devices
HUP1000385A2 (en) * 2010-07-21 2012-01-30 Medicontur Orvostechnikai Kft Alkane diol derivatives preparation thereof and based on them
TWI517861B (en) * 2011-02-08 2016-01-21 諾華公司 Low-tack, hydrophobic ophthalmic device materials
CA2848978C (en) * 2011-09-16 2020-01-14 Benz Research And Development Corp. Hydrophobic intraocular lens
FR3017800B1 (en) 2014-02-27 2016-03-04 Acrylian ACRYLIC, HYDROPHOBIC, RETICULATED COPOLYMER, BASED ON 2-PHENOXY-TETRAETHYLENE-GLYCOL ACRYLATE, FOR INTRAOCULAR LENSES
EP3251703A4 (en) * 2015-01-29 2018-08-08 Menicon Co., Ltd. Material for intraocular lenses and method for preserving material for intraocular lenses
EP3133065A1 (en) 2015-08-21 2017-02-22 Merck Patent GmbH Compounds for optically active devices
US10196470B2 (en) 2016-05-16 2019-02-05 Benz Research And Development Corp. Hydrophobic intraocular lens
US10894111B2 (en) 2016-12-16 2021-01-19 Benz Research And Development Corp. High refractive index hydrophilic materials
EP3363786A1 (en) 2017-02-15 2018-08-22 Merck Patent GmbH Compounds for optically active devices
EP3363793A1 (en) 2017-02-15 2018-08-22 Merck Patent GmbH Hydrophobic compounds for optically active devices
EP3502147A1 (en) 2017-12-22 2019-06-26 Merck Patent GmbH Composition for ophthalmological products
CN111154028A (en) * 2020-01-06 2020-05-15 东南大学 High-refractive-index corneal contact lens material and application thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5331073A (en) * 1992-11-09 1994-07-19 Allergan, Inc. Polymeric compositions and intraocular lenses made from same
MX9701015A (en) * 1995-06-07 1997-05-31 Alcon Lab Inc Improved high refractive index ophthalmic lens materials.
US6329485B1 (en) * 1998-12-11 2001-12-11 Bausch & Lomb Incorporated High refractive index hydrogel compositions for ophthalmic implants

Also Published As

Publication number Publication date
CN1371394A (en) 2002-09-25
BR0013779A (en) 2002-05-14
AU7070500A (en) 2001-04-10
WO2001018079A1 (en) 2001-03-15
EP1210381A1 (en) 2002-06-05
CA2381177A1 (en) 2001-03-15
JP2003508605A (en) 2003-03-04
AU766397B2 (en) 2003-10-16

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