AR019633A1 - Nuevos agentes terapeuticos para estructuras macromoleculares - Google Patents
Nuevos agentes terapeuticos para estructuras macromolecularesInfo
- Publication number
- AR019633A1 AR019633A1 ARP990102710A ARP990102710A AR019633A1 AR 019633 A1 AR019633 A1 AR 019633A1 AR P990102710 A ARP990102710 A AR P990102710A AR P990102710 A ARP990102710 A AR P990102710A AR 019633 A1 AR019633 A1 AR 019633A1
- Authority
- AR
- Argentina
- Prior art keywords
- macromolecular structures
- therapeutic agents
- new therapeutic
- multifixation
- bond
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
- C07K1/047—Simultaneous synthesis of different peptide species; Peptide libraries
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
Abstract
Se describe nuevos compuestos (agentes) de multifijacion, los cuales fijan a las estructuras macromoleculares, incluyendo componentes celulares,extracelulares y microbianos derivados de vectores, virus, hongos, levaduras, bacterias, etc. Los compuestos de esta comprenden varios ligandos cada uno de loscuales puede fijarse a tales estructuras macromoleculares, modulando así sus procesos/funciones biologicos. Cada uno de los ligandos está unido en formacovalente a un enlace (armazon) para proporcionar un compuesto de multifijacion. El enlace está seleccionado de modo que el compuesto de multifijacion asíconstruido presenta modulacion o alteracion aumentada de los procesos/funciones biologicos de la célula, en comparacion al agregado de las unidadesindividuales del ligando.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US8846498P | 1998-06-08 | 1998-06-08 | |
US9294198P | 1998-07-15 | 1998-07-15 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR019633A1 true AR019633A1 (es) | 2002-02-27 |
Family
ID=26778687
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP990102710A AR019633A1 (es) | 1998-06-08 | 1999-06-08 | Nuevos agentes terapeuticos para estructuras macromoleculares |
Country Status (7)
Country | Link |
---|---|
US (1) | US20030060663A1 (es) |
EP (1) | EP1079845A1 (es) |
AR (1) | AR019633A1 (es) |
AU (1) | AU4544099A (es) |
CA (1) | CA2319085A1 (es) |
SG (1) | SG106561A1 (es) |
WO (1) | WO1999064036A1 (es) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AUPQ288499A0 (en) | 1999-09-16 | 1999-10-07 | Biota Scientific Management Pty Ltd | Antiviral agents |
US6780602B2 (en) * | 2001-11-01 | 2004-08-24 | Microbiosystems, Limited Partnership | Taxonomic identification of pathogenic microorganisms and their toxic proteins |
US7825143B2 (en) | 2007-07-10 | 2010-11-02 | Montana State University - Billings | Method for controlling the yeast-to-filamentous growth transition in fungi |
US8883857B2 (en) | 2012-12-07 | 2014-11-11 | Baylor College Of Medicine | Small molecule xanthine oxidase inhibitors and methods of use |
CA3060372C (en) * | 2017-06-09 | 2022-04-05 | Dana-Farber Cancer Institute, Inc. | Improved methods for generating small molecule degraders and dimerizers |
CN108300677B (zh) * | 2018-02-22 | 2019-09-24 | 广东省微生物研究所(广东省微生物分析检测中心) | 一株白色链霉菌及其在制备微生物源防腐剂中的应用 |
CN113662961B (zh) * | 2021-07-19 | 2023-05-12 | 上海市第十人民医院 | 一种可捕获镁离子的微流控水凝胶微球及制备方法与应用 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU8730691A (en) * | 1990-09-28 | 1992-04-28 | Neorx Corporation | Polymeric carriers for release of covalently linked agents |
US5463564A (en) * | 1994-09-16 | 1995-10-31 | 3-Dimensional Pharmaceuticals, Inc. | System and method of automatically generating chemical compounds with desired properties |
WO1997035195A1 (en) * | 1996-03-19 | 1997-09-25 | The Salk Institute For Biological Studies | In vitro methods for identifying modulators of members of the steroid/thyroid superfamily of receptors |
US20020131972A1 (en) * | 1998-05-21 | 2002-09-19 | Daniel Sem | Multi-partite ligands and methods of identifying and using same |
-
1999
- 1999-06-07 WO PCT/US1999/011806 patent/WO1999064036A1/en not_active Application Discontinuation
- 1999-06-07 CA CA002319085A patent/CA2319085A1/en not_active Abandoned
- 1999-06-07 EP EP99928350A patent/EP1079845A1/en not_active Withdrawn
- 1999-06-07 AU AU45440/99A patent/AU4544099A/en not_active Abandoned
- 1999-06-08 SG SG9902718A patent/SG106561A1/en unknown
- 1999-06-08 AR ARP990102710A patent/AR019633A1/es unknown
-
2002
- 2002-03-08 US US10/096,270 patent/US20030060663A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
WO1999064036A9 (en) | 2000-03-02 |
EP1079845A4 (en) | 2001-03-07 |
WO1999064036A1 (en) | 1999-12-16 |
US20030060663A1 (en) | 2003-03-27 |
SG106561A1 (en) | 2004-10-29 |
AU4544099A (en) | 1999-12-30 |
EP1079845A1 (en) | 2001-03-07 |
CA2319085A1 (en) | 1999-12-16 |
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