AR019631A1 - Agentes terapeuticos nuevos que modulan receptores de 5-ht. - Google Patents

Agentes terapeuticos nuevos que modulan receptores de 5-ht.

Info

Publication number
AR019631A1
AR019631A1 ARP990102708A ARP990102708A AR019631A1 AR 019631 A1 AR019631 A1 AR 019631A1 AR P990102708 A ARP990102708 A AR P990102708A AR P990102708 A ARP990102708 A AR P990102708A AR 019631 A1 AR019631 A1 AR 019631A1
Authority
AR
Argentina
Prior art keywords
receivers
therapeutic agents
new therapeutic
agents modulating
compounds
Prior art date
Application number
ARP990102708A
Other languages
English (en)
Original Assignee
Advanced Medicine Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Advanced Medicine Inc filed Critical Advanced Medicine Inc
Publication of AR019631A1 publication Critical patent/AR019631A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/041—Heterocyclic compounds
    • A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K51/0446—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/545—Heterocyclic compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Revelacion de compuestos nuevos multiaglomerantes. Los compuestos de la invencion incluyen de 2-10 ligandos unidos con enlaces covalentes; cada unodedichos ligandos puede aglutinarse a un receptor de 5-HT y de este modo, modular los procesos / funciones biologicas de los mismos.
ARP990102708A 1998-06-08 1999-06-08 Agentes terapeuticos nuevos que modulan receptores de 5-ht. AR019631A1 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US8846698P 1998-06-08 1998-06-08
US9293898P 1998-07-15 1998-07-15
US9660698P 1998-08-14 1998-08-14

Publications (1)

Publication Number Publication Date
AR019631A1 true AR019631A1 (es) 2002-02-27

Family

ID=27375972

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP990102708A AR019631A1 (es) 1998-06-08 1999-06-08 Agentes terapeuticos nuevos que modulan receptores de 5-ht.

Country Status (6)

Country Link
EP (1) EP1083918A1 (es)
AR (1) AR019631A1 (es)
AU (1) AU4425399A (es)
CA (1) CA2319174A1 (es)
SG (1) SG83723A1 (es)
WO (1) WO1999064044A1 (es)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9903996D0 (sv) 1999-11-03 1999-11-03 Astra Ab New compounds
DE10037310A1 (de) 2000-07-28 2002-02-07 Asta Medica Ag Neue Indolderivate und deren Verwendung als Arzneimittel
US6444477B1 (en) * 2000-11-28 2002-09-03 Pharmagene Laboratories Limited Assay method for detecting 5-HT2B antagonists
WO2002060375A2 (en) * 2001-01-29 2002-08-08 Insight Strategy And Marketing Ltd Diphenyl ether derivatives and their uses as heparanase inhibitors
AU2003297048A1 (en) * 2002-12-13 2004-07-09 Smithkline Beecham Corporation Cyclohexyl compounds as ccr5 antagonists
SG146624A1 (en) 2003-09-11 2008-10-30 Kemia Inc Cytokine inhibitors
US7381732B2 (en) 2004-10-26 2008-06-03 Bristol-Myers Squibb Company Pyrazolobenzamides and derivatives as factor Xa inhibitors
WO2010123139A1 (ja) * 2009-04-24 2010-10-28 持田製薬株式会社 スルファモイル基を有するアリールカルボキサミド誘導体
RS57618B1 (sr) * 2013-08-02 2018-11-30 Pfizer Heterobicikloaril rorc2 inhibitori i postupci za njihovu upotrebu
US10485789B2 (en) 2014-07-24 2019-11-26 Sensor Pharmaceuticals, Inc. Compositions and methods for targeting receptors expressed in the gut
CN105439914B (zh) * 2014-09-17 2017-07-11 复旦大学 4‑氨酰基苯氧乙酰胺类化合物及其药物用途
EP3250561A1 (en) 2015-01-30 2017-12-06 Pfizer Inc Sulfonamide-subsituted indole modulators of rorc2 and methods of use thereof
WO2016120849A1 (en) 2015-01-30 2016-08-04 Pfizer Inc. Methoxy-substituted pyrrolopyridine modulators of rorc2 and methods of use thereof
MX2023002619A (es) * 2020-09-02 2023-04-10 Enveric Biosciences Canada Inc Derivados nitrados de psilocibina y uso de los mismos para modular el receptor 5-ht2a y para tratar un trastorno psiquiatrico.
WO2023044556A1 (en) * 2021-09-24 2023-03-30 Enveric Biosciences Canada Inc. Aminated psilocybin derivatives and methods of using

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU8730691A (en) * 1990-09-28 1992-04-28 Neorx Corporation Polymeric carriers for release of covalently linked agents
US5364856A (en) * 1991-03-28 1994-11-15 Eli Lilly And Company 6-heterocyclic-4-amino-1,3,4,5-tetrahydrobenz[CD]indoles
US5244912A (en) * 1991-03-28 1993-09-14 Eli Lilly And Company 6-heterocyclic-4-amino-1,3,4,5-tetrahydrobenz(cd)indoles and pharmaceutical use thereof
FR2712591B1 (fr) * 1993-11-19 1996-02-09 Pf Medicament Nouvelles arylpipérazines dérivées d'indole, leur préparation et leur utilisation thérapeutique.
GB9517559D0 (en) * 1995-08-26 1995-10-25 Smithkline Beecham Plc Novel compounds
AU2332497A (en) * 1996-03-19 1997-10-10 Salk Institute For Biological Studies, The (in vitro) methods for identifying modulators of members of the steroid/thyroid superfamily of receptors
US6500934B1 (en) * 1996-07-24 2002-12-31 Michael Rush Lerner Bivalent agonists for G-protein coupled receptors
WO1998011436A1 (en) * 1996-09-13 1998-03-19 Whitehead Institute For Biomedical Research Non-specific affinity enhancement to identify combinatorial library members
ZA9711376B (en) * 1996-12-20 1998-07-21 Lundbeck & Co As H Indole or dihydroindole derivatives

Also Published As

Publication number Publication date
CA2319174A1 (en) 1999-12-16
WO1999064044A1 (en) 1999-12-16
EP1083918A1 (en) 2001-03-21
SG83723A1 (en) 2001-10-16
AU4425399A (en) 1999-12-30

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