AR018868A1 - PHARMACEUTICAL COMPOSITIONS FOR MUSCLE SCHEME FRAGILITY, USE FOR THE PREPARATION OF MEDICINES, CASE - Google Patents
PHARMACEUTICAL COMPOSITIONS FOR MUSCLE SCHEME FRAGILITY, USE FOR THE PREPARATION OF MEDICINES, CASEInfo
- Publication number
- AR018868A1 AR018868A1 ARP990102847A ARP990102847A AR018868A1 AR 018868 A1 AR018868 A1 AR 018868A1 AR P990102847 A ARP990102847 A AR P990102847A AR P990102847 A ARP990102847 A AR P990102847A AR 018868 A1 AR018868 A1 AR 018868A1
- Authority
- AR
- Argentina
- Prior art keywords
- fragility
- compositions
- medicines
- preparation
- case
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Abstract
Se describen composiciones de combinacion farmacéutica y procedimientos, que comprenden (-)-cis-6-fenil-5-(4-(2-pirrolidin-1-il-etoxi)-fenil)-5,6,7,8-tetrahhidronaftaleno-2-ol o una sal farmacéuticamente aceptable del mismo y 2-amino-N-(1(R)-(2,4-difluoro-benciloximetil)-2-oxo-2-(3-oxo-3a(R)-piridin-2-ilmetil)-2-(2,2,2-trifluoro-etil)-2,3,3a,4,6,7-hexahidro-pirazolo[4,3-c]piridin-5-il)-2-metil-propionamida o una sal farmacéuticamente aceptable de lamisma, a procedimientos de uso de tales composiciones y a estuches que contienen tales composiciones. Las composiciones son utiles para el tratamientode la fragilidad musculoesquelética, incluyendo la osteoporosis, fracturas osteoporoticas, reduccion de masa osea, fragilidad y reduccion de masamuscular.Pharmaceutical combination compositions and methods are described, comprising (-) - cis-6-phenyl-5- (4- (2-pyrrolidin-1-yl-ethoxy) -phenyl) -5,6,7,8-tetrahydrophronaphthalene -2-ol or a pharmaceutically acceptable salt thereof and 2-amino-N- (1 (R) - (2,4-difluoro-benzyloxymethyl) -2-oxo-2- (3-oxo-3a (R) - pyridin-2-ylmethyl) -2- (2,2,2-trifluoro-ethyl) -2,3,3a, 4,6,7-hexahydro-pyrazolo [4,3-c] pyridin-5-yl) - 2-methyl-propionamide or a pharmaceutically acceptable salt thereof, to methods of using such compositions and cases containing such compositions. The compositions are useful for the treatment of musculoskeletal fragility, including osteoporosis, osteoporotic fractures, bone mass reduction, fragility and masamuscular reduction.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8942498P | 1998-06-16 | 1998-06-16 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR018868A1 true AR018868A1 (en) | 2001-12-12 |
Family
ID=22217565
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP990102847A AR018868A1 (en) | 1998-06-16 | 1999-06-15 | PHARMACEUTICAL COMPOSITIONS FOR MUSCLE SCHEME FRAGILITY, USE FOR THE PREPARATION OF MEDICINES, CASE |
Country Status (29)
| Country | Link |
|---|---|
| EP (1) | EP1085867A1 (en) |
| JP (1) | JP2002518328A (en) |
| KR (1) | KR20010052817A (en) |
| CN (1) | CN1305378A (en) |
| AP (1) | AP9901581A0 (en) |
| AR (1) | AR018868A1 (en) |
| AU (1) | AU3342099A (en) |
| BG (1) | BG105128A (en) |
| BR (1) | BR9911357A (en) |
| CA (1) | CA2335112A1 (en) |
| CO (1) | CO5070586A1 (en) |
| EA (1) | EA200001189A1 (en) |
| GT (1) | GT199900083A (en) |
| HR (1) | HRP20000857A2 (en) |
| HU (1) | HUP0102395A2 (en) |
| ID (1) | ID26726A (en) |
| IL (1) | IL139587A0 (en) |
| IS (1) | IS5727A (en) |
| MA (1) | MA26648A1 (en) |
| NO (1) | NO20006381D0 (en) |
| OA (1) | OA11569A (en) |
| PA (1) | PA8472101A1 (en) |
| PE (1) | PE20000633A1 (en) |
| PL (1) | PL345064A1 (en) |
| SK (1) | SK18902000A3 (en) |
| TN (1) | TNSN99118A1 (en) |
| UY (1) | UY25557A1 (en) |
| WO (1) | WO1999065488A1 (en) |
| ZA (1) | ZA993973B (en) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1004306A3 (en) * | 1998-08-06 | 2000-06-07 | Pfizer Products Inc. | Estrogen agonists/antagonists |
| BR0113626A (en) * | 2000-08-30 | 2003-06-17 | Pfizer Prod Inc | Sustained-Release Formulations for Growth Hormone Secretors |
| IL145106A0 (en) * | 2000-08-30 | 2002-06-30 | Pfizer Prod Inc | Intermittent administration of a geowth hormone secretagogue |
| CN100548283C (en) * | 2001-11-29 | 2009-10-14 | Gtx公司 | Osteoporosis prevention that androgen-deprivation causes and treatment |
| US7524866B2 (en) | 2001-11-29 | 2009-04-28 | Gtx, Inc. | Prevention and treatment of androgen—deprivation induced osteoporosis |
| US7476653B2 (en) | 2003-06-18 | 2009-01-13 | Tranzyme Pharma, Inc. | Macrocyclic modulators of the ghrelin receptor |
| CU23558A1 (en) | 2006-02-28 | 2010-07-20 | Ct Ingenieria Genetica Biotech | COMPOUNDS ANALOG TO THE PEPTIDIC SECRETAGOGS OF THE GROWTH HORMONE |
| EP2644618B1 (en) | 2007-02-09 | 2016-08-17 | Ocera Therapeutics, Inc. | tether intermediates for the synthesis of macrocyclic ghrelin receptor modulators |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UA51676C2 (en) * | 1995-11-02 | 2002-12-16 | Пфайзер Інк. | (-)cis-6(S)-phenyl-5(R)-[4-(2-pyrrolidin-I-ylethoxy)phenyl]-5,6,7,8-tetrahydronaphthalen-2-ol D-tartrate, a method of its preparation, method of THE treatment OF diseases medicated by agonists of estrogen and a pharmaceutical composition |
| TW432073B (en) * | 1995-12-28 | 2001-05-01 | Pfizer | Pyrazolopyridine compounds |
| HN1996000101A (en) * | 1996-02-28 | 1997-06-26 | Inc Pfizer | COMBINED THERAPY FOR OSTEOPOROSIS |
-
1999
- 1999-05-03 ID IDW20002604A patent/ID26726A/en unknown
- 1999-05-03 EA EA200001189A patent/EA200001189A1/en unknown
- 1999-05-03 PL PL99345064A patent/PL345064A1/en unknown
- 1999-05-03 OA OA1200000346A patent/OA11569A/en unknown
- 1999-05-03 BR BR9911357-0A patent/BR9911357A/en not_active Application Discontinuation
- 1999-05-03 JP JP2000554368A patent/JP2002518328A/en active Pending
- 1999-05-03 CN CN99807381A patent/CN1305378A/en active Pending
- 1999-05-03 SK SK1890-2000A patent/SK18902000A3/en unknown
- 1999-05-03 AU AU33420/99A patent/AU3342099A/en not_active Abandoned
- 1999-05-03 HU HU0102395A patent/HUP0102395A2/en unknown
- 1999-05-03 WO PCT/IB1999/000796 patent/WO1999065488A1/en not_active Application Discontinuation
- 1999-05-03 EP EP99914723A patent/EP1085867A1/en not_active Withdrawn
- 1999-05-03 CA CA002335112A patent/CA2335112A1/en not_active Abandoned
- 1999-05-03 KR KR1020007014140A patent/KR20010052817A/en not_active Application Discontinuation
- 1999-05-03 IL IL13958799A patent/IL139587A0/en unknown
- 1999-05-07 PA PA19998472101A patent/PA8472101A1/en unknown
- 1999-06-10 AP APAP/P/1999/001581A patent/AP9901581A0/en unknown
- 1999-06-11 UY UY25557A patent/UY25557A1/en not_active Application Discontinuation
- 1999-06-11 PE PE1999000522A patent/PE20000633A1/en not_active Application Discontinuation
- 1999-06-14 GT GT199900083A patent/GT199900083A/en unknown
- 1999-06-15 ZA ZA9903973A patent/ZA993973B/en unknown
- 1999-06-15 AR ARP990102847A patent/AR018868A1/en not_active Application Discontinuation
- 1999-06-15 TN TNTNSN99118A patent/TNSN99118A1/en unknown
- 1999-06-15 MA MA25622A patent/MA26648A1/en unknown
- 1999-06-16 CO CO99037624A patent/CO5070586A1/en unknown
-
2000
- 2000-11-24 IS IS5727A patent/IS5727A/en unknown
- 2000-12-14 HR HR20000857A patent/HRP20000857A2/en not_active Application Discontinuation
- 2000-12-14 NO NO20006381A patent/NO20006381D0/en not_active Application Discontinuation
-
2001
- 2001-01-08 BG BG105128A patent/BG105128A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| TNSN99118A1 (en) | 2005-11-10 |
| EA200001189A1 (en) | 2001-06-25 |
| MA26648A1 (en) | 2004-12-20 |
| HRP20000857A2 (en) | 2001-10-31 |
| PL345064A1 (en) | 2001-11-19 |
| CA2335112A1 (en) | 1999-12-23 |
| AU3342099A (en) | 2000-01-05 |
| ID26726A (en) | 2001-02-01 |
| PA8472101A1 (en) | 2000-09-29 |
| BR9911357A (en) | 2001-03-13 |
| OA11569A (en) | 2004-07-01 |
| BG105128A (en) | 2001-11-30 |
| CN1305378A (en) | 2001-07-25 |
| PE20000633A1 (en) | 2000-07-26 |
| AP9901581A0 (en) | 1999-06-30 |
| WO1999065488A1 (en) | 1999-12-23 |
| GT199900083A (en) | 2000-12-05 |
| EP1085867A1 (en) | 2001-03-28 |
| JP2002518328A (en) | 2002-06-25 |
| SK18902000A3 (en) | 2001-12-03 |
| NO20006381L (en) | 2000-12-14 |
| ZA993973B (en) | 2000-12-15 |
| NO20006381D0 (en) | 2000-12-14 |
| UY25557A1 (en) | 2001-01-31 |
| HUP0102395A2 (en) | 2001-11-28 |
| CO5070586A1 (en) | 2001-08-28 |
| IL139587A0 (en) | 2002-02-10 |
| IS5727A (en) | 2000-11-24 |
| KR20010052817A (en) | 2001-06-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal |