AR014119A1 - Utilizacion de cetolidas para la fabricacion de composiciones farmaceuticas destinadas a prevenir complicaciones tromboticas arteriales asociadas a laaterosclerosis - Google Patents

Utilizacion de cetolidas para la fabricacion de composiciones farmaceuticas destinadas a prevenir complicaciones tromboticas arteriales asociadas a laaterosclerosis

Info

Publication number
AR014119A1
AR014119A1 ARP980105823A ARP980105823A AR014119A1 AR 014119 A1 AR014119 A1 AR 014119A1 AR P980105823 A ARP980105823 A AR P980105823A AR P980105823 A ARP980105823 A AR P980105823A AR 014119 A1 AR014119 A1 AR 014119A1
Authority
AR
Argentina
Prior art keywords
pharmaceutical compositions
complications associated
compositions intended
laterosclerosis
cetolids
Prior art date
Application number
ARP980105823A
Other languages
English (en)
Original Assignee
Hoechst Marion Roussel Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Marion Roussel Inc filed Critical Hoechst Marion Roussel Inc
Publication of AR014119A1 publication Critical patent/AR014119A1/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

Se describe la utilizacion de cetolidas para la preparacion de composiciones farmacéuticas destinadas a prevenir las complicacionestromboticas arteriales asociadas a la aterosclerosis. Las cetolidas responden a la formula (I) en la cualR representa un radical (CH2)mOn(X)YAr en la cual mrepresenta el numero 0 o 1, n representa el numero 0 o 1, X representa un radical (NH)a, CH2 o SO2, representando al numero 0 o 1, Y representa unradical (CH2)b-(CH=CH)c-(CH2)d con c= 0 o 1, b+ c + d < o = que 8, Z representa un átomo de hidrogeno o de halogeno, y Ar representa un radicalarilo o heteroarilo eventualmente sustituido.
ARP980105823A 1997-11-17 1998-11-17 Utilizacion de cetolidas para la fabricacion de composiciones farmaceuticas destinadas a prevenir complicaciones tromboticas arteriales asociadas a laaterosclerosis AR014119A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9714358A FR2771008B1 (fr) 1997-11-17 1997-11-17 Utilisation des ketolides pour la preparation de compositions pharmaceutiques destinees a prevenir les complications thrombotiques arterielles liees a l'atherosclerose

Publications (1)

Publication Number Publication Date
AR014119A1 true AR014119A1 (es) 2001-02-07

Family

ID=9513423

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP980105823A AR014119A1 (es) 1997-11-17 1998-11-17 Utilizacion de cetolidas para la fabricacion de composiciones farmaceuticas destinadas a prevenir complicaciones tromboticas arteriales asociadas a laaterosclerosis

Country Status (35)

Country Link
US (1) US20080139489A1 (es)
EP (1) EP1030673B1 (es)
JP (1) JP4550273B2 (es)
KR (1) KR20010032130A (es)
CN (1) CN1286633A (es)
AP (1) AP1196A (es)
AR (1) AR014119A1 (es)
AT (1) ATE271875T1 (es)
AU (1) AU744419B2 (es)
BG (1) BG104427A (es)
BR (1) BR9814199A (es)
CA (1) CA2312021C (es)
DE (1) DE69825308T2 (es)
DZ (1) DZ2654A1 (es)
EA (1) EA003322B1 (es)
EE (1) EE04095B1 (es)
ES (1) ES2224446T3 (es)
FR (1) FR2771008B1 (es)
GE (1) GEP20032968B (es)
HR (1) HRP20000314A2 (es)
HU (1) HUP0004507A3 (es)
ID (1) ID24940A (es)
IL (1) IL136149A0 (es)
MA (1) MA26566A1 (es)
NO (1) NO20002435L (es)
NZ (1) NZ504305A (es)
OA (1) OA11411A (es)
PL (1) PL340373A1 (es)
SK (1) SK7042000A3 (es)
TN (1) TNSN98206A1 (es)
TR (1) TR200001384T2 (es)
TW (1) TW472061B (es)
WO (1) WO1999025365A1 (es)
YU (1) YU29600A (es)
ZA (1) ZA9810357B (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2777282B1 (fr) * 1998-04-08 2001-04-20 Hoechst Marion Roussel Inc Nouveaux derives de la 2-fluoro 3-de((2,6-dideoxy 3-c-methyl 3-0-methyl-alpha-l-ribohexopyranosyl) oxyl) 6-o-methyl 3-oxo erythromycine, leur procede de preparation et leur application a la synthese de principes actifs de medicaments
EP1137654A1 (en) * 1998-12-10 2001-10-04 Pfizer Products Inc. Carbamate and carbazate ketolide antibiotics
DK1147121T3 (da) * 1999-01-27 2004-04-13 Pfizer Prod Inc Ketolidantibiotika
EP1114826A3 (en) * 1999-12-29 2001-10-31 Pfizer Products Inc. Novel antibacterial and prokinetic macrolides
DE60139382D1 (de) 2000-04-04 2009-09-10 Smithkline Beecham Plc 2-hydroxy-mutilin-carbamat derivate und ihre anwendung als antibakterielle mittel
JP2004323414A (ja) * 2003-04-24 2004-11-18 Japan Science & Technology Agency 14員環マクロライド化合物を利用した、血管平滑筋の増殖に起因する疾患治療剤
GB0402578D0 (en) * 2004-02-05 2004-03-10 Cambridge Theranostics Ltd Methods of treatment of atherosclerosis
JP6042334B2 (ja) * 2010-09-10 2016-12-14 センプラ ファーマシューティカルズ,インコーポレイテッド 疾患治療のための水素結合形成フルオロケトライド

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5424187A (en) * 1991-06-14 1995-06-13 Board Of Regents Of The University Of Washington Method of screening for arterial chlamydial granuloma
FR2718450B1 (fr) * 1994-04-08 1997-01-10 Roussel Uclaf Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.
FR2719587B1 (fr) * 1994-05-03 1996-07-12 Roussel Uclaf Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.
FR2742757B1 (fr) * 1995-12-22 1998-01-30 Roussel Uclaf Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
US6271255B1 (en) * 1996-07-05 2001-08-07 Biotica Technology Limited Erythromycins and process for their preparation
GB9621771D0 (en) * 1996-10-18 1996-12-11 St George S Enterprises Ltd Method of treatment of heart disease
FR2757168B1 (fr) * 1996-12-12 1999-06-11 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
EP0895999A1 (en) * 1997-08-06 1999-02-10 Pfizer Products Inc. C-4" substituted macrolide antibiotics

Also Published As

Publication number Publication date
DE69825308D1 (de) 2004-09-02
FR2771008B1 (fr) 2000-04-28
ATE271875T1 (de) 2004-08-15
PL340373A1 (en) 2001-01-29
ZA9810357B (en) 1999-11-12
EP1030673B1 (fr) 2004-07-28
AP2000001825A0 (en) 2000-06-30
TNSN98206A1 (fr) 2005-03-15
BG104427A (en) 2001-02-28
IL136149A0 (en) 2001-05-20
HUP0004507A3 (en) 2001-12-28
TW472061B (en) 2002-01-11
EP1030673A1 (fr) 2000-08-30
AU744419B2 (en) 2002-02-21
EE200000244A (et) 2001-06-15
OA11411A (fr) 2004-04-20
MA26566A1 (fr) 2004-12-20
DZ2654A1 (fr) 2003-03-22
NO20002435D0 (no) 2000-05-11
ID24940A (id) 2000-08-31
EE04095B1 (et) 2003-08-15
CA2312021A1 (fr) 1999-05-27
SK7042000A3 (en) 2000-12-11
NO20002435L (no) 2000-07-07
US20080139489A1 (en) 2008-06-12
DE69825308T2 (de) 2005-08-04
BR9814199A (pt) 2000-09-26
AU1242599A (en) 1999-06-07
GEP20032968B (en) 2003-05-27
HUP0004507A1 (hu) 2001-05-28
YU29600A (sh) 2003-02-28
ES2224446T3 (es) 2005-03-01
EA200000531A1 (ru) 2000-10-30
JP4550273B2 (ja) 2010-09-22
NZ504305A (en) 2002-11-26
CA2312021C (fr) 2008-08-26
HRP20000314A2 (en) 2001-02-28
AP1196A (en) 2003-08-18
WO1999025365A1 (fr) 1999-05-27
TR200001384T2 (tr) 2001-06-21
EA003322B1 (ru) 2003-04-24
FR2771008A1 (fr) 1999-05-21
JP2001523644A (ja) 2001-11-27
KR20010032130A (ko) 2001-04-16
CN1286633A (zh) 2001-03-07

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