AR013160A1 - POLYMORPHIC FORM OF AN ANTAGONIST RECEIVER OF TACHYQUININE, PHARMACEUTICAL COMPOSITION, USE OF THE SAME FOR THE PREPARATION OF MEDICINES. - Google Patents

POLYMORPHIC FORM OF AN ANTAGONIST RECEIVER OF TACHYQUININE, PHARMACEUTICAL COMPOSITION, USE OF THE SAME FOR THE PREPARATION OF MEDICINES.

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Publication number
AR013160A1
AR013160A1 ARP980103199A AR013160A1 AR 013160 A1 AR013160 A1 AR 013160A1 AR P980103199 A ARP980103199 A AR P980103199A AR 013160 A1 AR013160 A1 AR 013160A1
Authority
AR
Argentina
Prior art keywords
phenyl
preparation
polymorphic form
tachyquinine
antagonist
Prior art date
Application number
Other languages
Spanish (es)
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of AR013160A1 publication Critical patent/AR013160A1/en

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

Forma polimorfica del compuesto 2-(R)-(1-(R)-(3,5-bis(trifluormetil)fenil) etoxi)-3-(S)-(4-fluor)fenil-4-(3-(5-oxo-1H,4H-1,2,4-triazol)metilmorfolina,antagonista receptor de taquiquinina util en el tratamiento o prevencion de los desordenes delsistema nervioso central, enfermedades inflamatorias, doloro migrana, asma y emesis. La misma tiene ventajas con respecto a las otras formas de2-(R)-(1-(R)-(3,5-bis(trifluormetil)fenil)etoxi)-3-(S)-(4-fluor)fenil)-4-(3-(5-oxo-1H,4H-1,2,4-triazo l)metil-morfolina en términos de estabilidad termodinámica y conveniencia para inclusion en formulacionesfarmacéuticas, composicionfarmacéutica, uso de dicha forma para preparar medicamentos, procedimientos para su preparacion y prod uctos producidos pordichos procedimientos.Polymorphic form of compound 2- (R) - (1- (R) - (3,5-bis (trifluormethyl) phenyl) ethoxy) -3- (S) - (4-fluor) phenyl-4- (3- ( 5-oxo-1H, 4H-1,2,4-triazole) methylmorpholine, a tachykinin receptor antagonist useful in the treatment or prevention of central nervous system disorders, inflammatory diseases, migraine pain, asthma, and emesis. relative to the other forms of 2- (R) - (1- (R) - (3,5-bis (trifluormethyl) phenyl) ethoxy) -3- (S) - (4-fluor) phenyl) -4- (3 - (5-oxo-1H, 4H-1,2,4-triazo l) methyl-morpholine in terms of thermodynamic stability and suitability for inclusion in pharmaceutical, compositional-pharmaceutical formulations, use of said form to prepare drugs, procedures for their preparation and prod ucts produced by said procedures.

ARP980103199 1997-07-02 1998-07-01 POLYMORPHIC FORM OF AN ANTAGONIST RECEIVER OF TACHYQUININE, PHARMACEUTICAL COMPOSITION, USE OF THE SAME FOR THE PREPARATION OF MEDICINES. AR013160A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US5160097P 1997-07-02 1997-07-02
GBGB9800216.5A GB9800216D0 (en) 1998-01-07 1998-01-07 Polymorphic form of a tachykinin receptor antagonist

Publications (1)

Publication Number Publication Date
AR013160A1 true AR013160A1 (en) 2000-12-13

Family

ID=10824888

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP980103199 AR013160A1 (en) 1997-07-02 1998-07-01 POLYMORPHIC FORM OF AN ANTAGONIST RECEIVER OF TACHYQUININE, PHARMACEUTICAL COMPOSITION, USE OF THE SAME FOR THE PREPARATION OF MEDICINES.

Country Status (6)

Country Link
AR (1) AR013160A1 (en)
CO (1) CO4940431A1 (en)
GB (1) GB9800216D0 (en)
MY (1) MY126509A (en)
RS (1) RS49980B (en)
UA (1) UA57089C2 (en)

Also Published As

Publication number Publication date
CO4940431A1 (en) 2000-07-24
RS49980B (en) 2008-09-29
UA57089C2 (en) 2003-06-16
GB9800216D0 (en) 1998-03-04
MY126509A (en) 2006-10-31

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