AR012972A1 - PHARMACEUTICAL FORM FOR THE ADMINISTRATION OF PACLITAXEL, PROCESS FOR THE PREPARATION OF A READY-TO-USE PACLITAXEL COMPOSITION AND USE OF THIS COMPOSITION - Google Patents

PHARMACEUTICAL FORM FOR THE ADMINISTRATION OF PACLITAXEL, PROCESS FOR THE PREPARATION OF A READY-TO-USE PACLITAXEL COMPOSITION AND USE OF THIS COMPOSITION

Info

Publication number
AR012972A1
AR012972A1 ARP980102786A ARP980102786A AR012972A1 AR 012972 A1 AR012972 A1 AR 012972A1 AR P980102786 A ARP980102786 A AR P980102786A AR P980102786 A ARP980102786 A AR P980102786A AR 012972 A1 AR012972 A1 AR 012972A1
Authority
AR
Argentina
Prior art keywords
paclitaxel
composition
ready
administration
preparation
Prior art date
Application number
ARP980102786A
Other languages
Spanish (es)
Original Assignee
Lab Thissen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lab Thissen filed Critical Lab Thissen
Publication of AR012972A1 publication Critical patent/AR012972A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dispersion Chemistry (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La forma farmacéutica para la administracion de paclitaxel comprende dos botellas diferentes, una de las cuales contiene una solucion etanolica depaclitaxel y la otra contiene una solucion etanolica de Cremofor EL, Cremofor EL-P o de una mezclade las dos; se intenta que el contenido de estas botellasse mezcle, al menos en el momento de dar la inyeccion al paciente, y además, el proceso para la preparacion de una composicion de paclitaxel estable lista parausar.The pharmaceutical form for administration of paclitaxel comprises two different bottles, one of which contains a depaclitaxel ethanol solution and the other containing an ethanol solution of Cremofor EL, Cremofor EL-P or a mixture of the two; The content of these bottles is intended to be mixed, at least at the time of injection to the patient, and further, the process for the preparation of a ready-to-use stable paclitaxel composition.

ARP980102786A 1997-06-13 1998-06-11 PHARMACEUTICAL FORM FOR THE ADMINISTRATION OF PACLITAXEL, PROCESS FOR THE PREPARATION OF A READY-TO-USE PACLITAXEL COMPOSITION AND USE OF THIS COMPOSITION AR012972A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
BE9700515A BE1011216A3 (en) 1997-06-13 1997-06-13 Pharmaceutical form for the administration of paclitaxel, method of preparation of a composition paclitaxel ready to employment and use thereof.

Publications (1)

Publication Number Publication Date
AR012972A1 true AR012972A1 (en) 2000-11-22

Family

ID=3890575

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP980102786A AR012972A1 (en) 1997-06-13 1998-06-11 PHARMACEUTICAL FORM FOR THE ADMINISTRATION OF PACLITAXEL, PROCESS FOR THE PREPARATION OF A READY-TO-USE PACLITAXEL COMPOSITION AND USE OF THIS COMPOSITION

Country Status (5)

Country Link
AR (1) AR012972A1 (en)
AU (1) AU7632198A (en)
BE (1) BE1011216A3 (en)
WO (1) WO1998057630A1 (en)
ZA (1) ZA984832B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6964946B1 (en) * 1995-10-26 2005-11-15 Baker Norton Pharmaceuticals, Inc. Oral pharmaceutical compositions containing taxanes and methods of treatment employing the same
WO2002058689A1 (en) 2000-12-05 2002-08-01 Childrens Hospital Los Angeles Pharmaceutical compositions of fenretinide having increased bioavailability and methods of using the same
EP1498143A1 (en) * 2003-07-18 2005-01-19 Aventis Pharma S.A. Self-emulsifying and self-microemulsifying formulations for the oral administration of taxoids
CA2532110A1 (en) * 2003-07-24 2005-02-24 Dabur Research Foundation Process for the purification of non-ionic solvents for stabilized injectable pharmaceutical formulations
US20050016926A1 (en) 2003-07-24 2005-01-27 Dabur Research Foundation Stabilized formulation
CN1853728A (en) * 2005-04-19 2006-11-01 上海天博生物科技有限公司 Method prescription and use for improving medicine or nutrient oral absorption

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2601675B1 (en) * 1986-07-17 1988-09-23 Rhone Poulenc Sante TAXOL DERIVATIVES, THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
US4960790A (en) * 1989-03-09 1990-10-02 University Of Kansas Derivatives of taxol, pharmaceutical compositions thereof and methods for the preparation thereof
FR2678833B1 (en) * 1991-07-08 1995-04-07 Rhone Poulenc Rorer Sa NEW PHARMACEUTICAL COMPOSITIONS BASED ON DERIVATIVES OF THE TAXANE CLASS.
EP1500393A1 (en) * 1992-11-27 2005-01-26 Mayne Pharma (USA) Inc. Injectable composition containing taxol
NZ258044A (en) * 1992-11-27 1995-12-21 Faulding F H & Co Ltd Pharmaceutical composition comprising taxol, solubilising agent, an acid and an organic solvent
FR2698543B1 (en) * 1992-12-02 1994-12-30 Rhone Poulenc Rorer Sa New taxoid-based compositions.
TW406020B (en) * 1993-09-29 2000-09-21 Bristol Myers Squibb Co Stabilized pharmaceutical composition and its method for preparation and stabilizing solvent
US5681846A (en) * 1995-03-17 1997-10-28 Board Of Regents, The University Of Texas System Extended stability formulations for paclitaxel

Also Published As

Publication number Publication date
WO1998057630A1 (en) 1998-12-23
ZA984832B (en) 1999-01-04
AU7632198A (en) 1999-01-04
BE1011216A3 (en) 1999-06-01

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