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Priority to ARP970100260ApriorityCriticalpatent/AR005520A1/en
Publication of AR005520A1publicationCriticalpatent/AR005520A1/en
Un proceso para la formación de 5-(alquilo, o, alcoxi) carbonil-6-alquil-4- (aril, o, alquil)-3-4-2(1H)-dihidropirimidinonas combinando un beta-cetoéstero dicetona, un aldehído y urea en presencia de un reactivo de boro, una sal de material (por ejemplo, Cu2O) y un catalizador (por ejemplo, ácido). La reacciónse lleva a cabo, típicamente en un recipiente en un disolvente para obtener dihidropirimidinonas con rendimientos más altos y con una más fácilpreparación que con los métodos conocidospreviamente.A process for the formation of 5- (alkyl, o, alkoxy) carbonyl-6-alkyl-4- (aryl, o, alkyl) -3-4-2 (1H) -dihydropyrimidinones by combining a beta-ketoester diketone, an aldehyde and urea in the presence of a boron reagent, a material salt (eg, Cu2O), and a catalyst (eg, acid). The reaction is typically carried out in a container in a solvent to obtain dihydropyrimidinones in higher yields and with easier preparation than with previously known methods.
ARP970100260A1997-01-221997-01-22
PROCESS FOR THE PREPARATION OF DIHIDROPIRIMIDINONAS.
AR005520A1
(en)
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