AR004780A1 - Derivados de 2-tioxo-imidazolidin-4-ona - Google Patents

Derivados de 2-tioxo-imidazolidin-4-ona

Info

Publication number
AR004780A1
AR004780A1 ARP960105364A ARP960105364A AR004780A1 AR 004780 A1 AR004780 A1 AR 004780A1 AR P960105364 A ARP960105364 A AR P960105364A AR P960105364 A ARP960105364 A AR P960105364A AR 004780 A1 AR004780 A1 AR 004780A1
Authority
AR
Argentina
Prior art keywords
imidazolidin
thioxo
alkyl
ona
derivatives
Prior art date
Application number
ARP960105364A
Other languages
English (en)
Original Assignee
American Home Prod
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Home Prod filed Critical American Home Prod
Publication of AR004780A1 publication Critical patent/AR004780A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/86—Oxygen and sulfur atoms, e.g. thiohydantoin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

El compuesto de la fórmula (I) en el que R1 es un alquilo; y R es un alquilo, naftilo, benzhidrilo, fluorofenilmetil, fenetil, 1-(fluorofenil)etil,5-cloro-2-metoxifenil, trifluorometoxifenil, trifluorometilfenil, metilsulfanilfenil o piridin y son útiles para aumentar los niveles de HDL delsuero en sangre.
ARP960105364A 1995-11-28 1996-11-27 Derivados de 2-tioxo-imidazolidin-4-ona AR004780A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US766195P 1995-11-28 1995-11-28

Publications (1)

Publication Number Publication Date
AR004780A1 true AR004780A1 (es) 1999-03-10

Family

ID=21727455

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP960105364A AR004780A1 (es) 1995-11-28 1996-11-27 Derivados de 2-tioxo-imidazolidin-4-ona

Country Status (3)

Country Link
US (1) US5783707A (es)
AR (1) AR004780A1 (es)
TW (1) TW418195B (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE319712T1 (de) 1999-12-21 2006-03-15 Mgi Gp Inc Hydantoin derivate, pharmazeutische zusammensetzungen und verfahren zu ihrer verwendung
US7709517B2 (en) 2005-05-13 2010-05-04 The Regents Of The University Of California Diarylhydantoin compounds
AU2013205325B2 (en) * 2006-03-27 2016-03-24 The Regents Of The University Of California Androgen receptor modulator for the treatment of prostate cancer and androgen receptor-associated diseases
HUE053877T2 (hu) * 2006-03-27 2021-07-28 Univ California Androgén receptormodulátor a prosztatarák és az androgén receptorral összefüggõ betegségek kezeléséhez
AU2016201061B2 (en) * 2006-03-27 2017-03-02 The Regents Of The University Of California Androgen receptor modulator for the treatment of prostate cancer and androgen receptor-associated diseases
NZ572374A (en) 2006-03-29 2011-12-22 Univ California Diarylthiohydantoin compounds
CA2703635C (en) 2007-10-26 2017-06-27 Michael E. Jung Diarylhydantoin compounds as androgen receptor modulators
MX2011011964A (es) 2009-05-12 2012-02-23 Janssen Pharmaceuticals Inc Derivados de 1,2,3-triazolo[4,3-a]piridina y su uso para el tratamiento o prevencion de trastornos neurologicos y psiquiatricos.
CN106983749A (zh) 2010-02-16 2017-07-28 亚拉冈制药公司 雄激素受体调节剂及其用途
BR112015006705A8 (pt) 2012-09-26 2019-08-27 Aragon Pharmaceuticals Inc antiandrogênios para o tratamento de câncer de próstata resistente à castração não metastático e usos destes
JOP20200097A1 (ar) 2013-01-15 2017-06-16 Aragon Pharmaceuticals Inc معدل مستقبل أندروجين واستخداماته
TWI726969B (zh) 2016-01-11 2021-05-11 比利時商健生藥品公司 用作雄性激素受體拮抗劑之經取代之硫尿囊素衍生物
CA3079135A1 (en) 2017-10-16 2019-04-25 Arturo Molina Anti-androgens for the treatment of non-metastatic castration-resistant prostate cancer

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2551134A (en) * 1947-05-15 1951-05-01 Du Pont Process of color developing with 2-thiohydantoin derivatives
US2649459A (en) * 1950-09-08 1953-08-18 Eastman Kodak Co 2-thiohydantoins containing a carboxyaryl group and method of preparation
US3134663A (en) * 1957-07-23 1964-05-26 Geigy Chem Corp Herbicidal composition and method employing hydantoins
JPS4887030A (es) * 1972-02-24 1973-11-16
US3923994A (en) * 1973-07-13 1975-12-02 Smithkline Corp Anti-arthritic compositions comprising a 3-aryl 2-thiohydantoin and methods of producing anti-arthritic acitvity
US4473393A (en) * 1982-08-06 1984-09-25 Buffalo Color Corporation Pesticidal thiohydantoin compositions
DE3604042A1 (de) * 1986-02-08 1987-08-13 Hoechst Ag Imidazolidin(thi)on-derivate, verfahren zu ihrer herstellung sowie ihre verwendung im pflanzenschutz
US5137904A (en) * 1989-05-30 1992-08-11 G. D. Searle & Co. Thiohydantoin inhibitors of collagen-induced and ADP-induced platelet aggregation
US5411981A (en) * 1991-01-09 1995-05-02 Roussel Uclaf Phenylimidazolidines having antiandrogenic activity
JPH04297461A (ja) * 1991-03-27 1992-10-21 Otsuka Pharmaceut Factory Inc ２−チオヒダントイン誘導体
DE4207254A1 (de) * 1992-03-07 1993-09-09 Cassella Ag 4-oxo-2-thioxoimidazolidin-derivate
FR2694290B1 (fr) * 1992-07-08 1994-09-02 Roussel Uclaf Nouvelles phénylimidazolidines éventuellement substituées, leur procédé de préparation, leur application comme médicaments et les compositions pharmaceutiques les renfermant.
DE4228717A1 (de) * 1992-08-28 1994-03-03 Cassella Ag Imidazolidin-Derivate
WO1994020460A1 (en) * 1993-03-11 1994-09-15 Smithkline Beecham Corporation Chemical compounds

Also Published As

Publication number Publication date
US5783707A (en) 1998-07-21
TW418195B (en) 2001-01-11

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