AR002541A1 - Inhibidores de la ribonucleotido-reductasa de herpes. - Google Patents
Inhibidores de la ribonucleotido-reductasa de herpes.Info
- Publication number
- AR002541A1 AR002541A1 ARP960103241A AR10324196A AR002541A1 AR 002541 A1 AR002541 A1 AR 002541A1 AR P960103241 A ARP960103241 A AR P960103241A AR 10324196 A AR10324196 A AR 10324196A AR 002541 A1 AR002541 A1 AR 002541A1
- Authority
- AR
- Argentina
- Prior art keywords
- reductase inhibitors
- herpes ribonucleotide
- ribonucleotide
- herpes
- alkyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/22—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16611—Simplexvirus, e.g. human herpesvirus 1, 2
- C12N2710/16622—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Animal Behavior & Ethology (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Se describen aquí compuestos de la fórmula (I), en la que R1 es hidrógeno o alquilo (1-4C), R2 es alquilo (1-4C) o una de sus sales terapéuticamenteaceptables. Los compuestos son útiles para tratar infecciones por herpes.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA002152541A CA2152541C (en) | 1995-06-23 | 1995-06-23 | Herpes ribonucleotide reductase inhibitors |
Publications (1)
Publication Number | Publication Date |
---|---|
AR002541A1 true AR002541A1 (es) | 1998-03-25 |
Family
ID=4156109
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP960103241A AR002541A1 (es) | 1995-06-23 | 1996-06-21 | Inhibidores de la ribonucleotido-reductasa de herpes. |
Country Status (11)
Country | Link |
---|---|
US (1) | US5672586A (es) |
EP (1) | EP0837845B1 (es) |
JP (1) | JPH11508246A (es) |
AR (1) | AR002541A1 (es) |
AT (1) | ATE209628T1 (es) |
AU (1) | AU5097796A (es) |
CA (1) | CA2152541C (es) |
DE (1) | DE69617433T2 (es) |
IL (1) | IL118705A0 (es) |
WO (1) | WO1997000855A1 (es) |
ZA (1) | ZA965272B (es) |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4795740A (en) * | 1986-05-20 | 1989-01-03 | Cohen Eric A | Antiviral peptides and means for treating herpes infections |
US4814432A (en) * | 1987-05-22 | 1989-03-21 | Merck & Co., Inc. | Inhibitor of ribonucleotide reductase |
EP0411334B1 (en) * | 1989-07-07 | 1995-02-22 | Bio-Mega/Boehringer Ingelheim Research Inc. | Antiherpes pentapeptide derivatives having a substituted aspartic acid side chain |
US5110799A (en) * | 1989-07-28 | 1992-05-05 | Merck & Co., Inc. | Antiherpetic agents |
ATE169931T1 (de) * | 1992-03-12 | 1998-09-15 | Boehringer Ingelheim Ca Ltd | Isosterische peptidderivate gegen herpes |
US5574015A (en) * | 1992-03-12 | 1996-11-12 | Bio-Mega/Boehringer Ingelheim Research Inc. | Isosteric antiherpes peptide derivatives |
EP0560274B1 (en) * | 1992-03-12 | 1998-06-24 | Boehringer Ingelheim (Canada) Ltd. | Antiherpes peptide derivatives having a ureido N-terminus |
PT618226E (pt) * | 1993-03-03 | 2001-03-30 | Boehringer Ingelheim Ca Ltd | Inibidores de ribonucleotido redutase de virus do herpes |
-
1995
- 1995-06-23 CA CA002152541A patent/CA2152541C/en not_active Expired - Fee Related
-
1996
- 1996-03-27 DE DE69617433T patent/DE69617433T2/de not_active Expired - Fee Related
- 1996-03-27 AT AT96907230T patent/ATE209628T1/de not_active IP Right Cessation
- 1996-03-27 AU AU50977/96A patent/AU5097796A/en not_active Abandoned
- 1996-03-27 WO PCT/CA1996/000180 patent/WO1997000855A1/en active IP Right Grant
- 1996-03-27 EP EP96907230A patent/EP0837845B1/en not_active Expired - Lifetime
- 1996-03-27 JP JP9503484A patent/JPH11508246A/ja not_active Abandoned
- 1996-06-18 US US08/666,732 patent/US5672586A/en not_active Expired - Fee Related
- 1996-06-21 AR ARP960103241A patent/AR002541A1/es unknown
- 1996-06-21 IL IL11870596A patent/IL118705A0/xx unknown
- 1996-06-21 ZA ZA965272A patent/ZA965272B/xx unknown
Also Published As
Publication number | Publication date |
---|---|
CA2152541C (en) | 1998-12-15 |
EP0837845B1 (en) | 2001-11-28 |
ATE209628T1 (de) | 2001-12-15 |
AU5097796A (en) | 1997-01-22 |
DE69617433T2 (de) | 2002-06-27 |
IL118705A0 (en) | 1996-10-16 |
DE69617433D1 (de) | 2002-01-10 |
US5672586A (en) | 1997-09-30 |
CA2152541A1 (en) | 1996-12-24 |
EP0837845A1 (en) | 1998-04-29 |
MX9710147A (es) | 1998-03-31 |
JPH11508246A (ja) | 1999-07-21 |
ZA965272B (en) | 1996-12-23 |
WO1997000855A1 (en) | 1997-01-09 |
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