AP2804A - Amide comounds as boosters of antivirals - Google Patents

Amide comounds as boosters of antivirals

Info

Publication number
AP2804A
AP2804A AP2010005285A AP2010005285A AP2804A AP 2804 A AP2804 A AP 2804A AP 2010005285 A AP2010005285 A AP 2010005285A AP 2010005285 A AP2010005285 A AP 2010005285A AP 2804 A AP2804 A AP 2804A
Authority
AP
ARIPO
Prior art keywords
comounds
antivirals
boosters
amide
amide comounds
Prior art date
Application number
AP2010005285A
Other languages
English (en)
Other versions
AP2010005285A0 (en
Inventor
Tim Hugo Maria Jonckers
Wim Bert Griet Schepens
Geerwin Yvonne Paul Hache
Original Assignee
Tibotec Pharm Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39386111&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AP2804(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Tibotec Pharm Ltd filed Critical Tibotec Pharm Ltd
Publication of AP2010005285A0 publication Critical patent/AP2010005285A0/en
Application granted granted Critical
Publication of AP2804A publication Critical patent/AP2804A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D277/82—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AP2010005285A 2007-12-06 2008-12-05 Amide comounds as boosters of antivirals AP2804A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP07122468 2007-12-06
PCT/EP2008/066847 WO2009071650A2 (en) 2007-12-06 2008-12-05 Amide compounds as boosters of antivirals

Publications (2)

Publication Number Publication Date
AP2010005285A0 AP2010005285A0 (en) 2010-06-30
AP2804A true AP2804A (en) 2013-11-30

Family

ID=39386111

Family Applications (1)

Application Number Title Priority Date Filing Date
AP2010005285A AP2804A (en) 2007-12-06 2008-12-05 Amide comounds as boosters of antivirals

Country Status (23)

Country Link
US (1) US8350048B2 (he)
EP (1) EP2235008B1 (he)
JP (1) JP5509092B2 (he)
KR (1) KR101624675B1 (he)
CN (1) CN101878210B (he)
AP (1) AP2804A (he)
AR (1) AR069595A1 (he)
AU (1) AU2008333165B2 (he)
BR (1) BRPI0821021A2 (he)
CA (1) CA2706155C (he)
CL (1) CL2008003639A1 (he)
EA (1) EA019616B1 (he)
IL (1) IL205489A (he)
MX (1) MX2010006166A (he)
MY (1) MY151005A (he)
NZ (1) NZ585652A (he)
PA (1) PA8806801A1 (he)
PE (1) PE20091263A1 (he)
TW (1) TWI438202B (he)
UA (1) UA103013C2 (he)
UY (1) UY31513A1 (he)
WO (1) WO2009071650A2 (he)
ZA (1) ZA201004025B (he)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA026673B1 (ru) * 2008-10-07 2017-05-31 Янссен Сайенсиз Айрлэнд Юси Амидные соединения в качестве усилителей противовирусных препаратов
BR112012004969A2 (pt) * 2009-09-03 2019-09-24 Tibotec Pharm Ltd derivados de bis-benzimidazol
EA201290808A1 (ru) 2010-02-18 2013-03-29 ХАЙ ПОЙНТ ФАРМАСЬЮТИКАЛЗ, ЭлЭлСи Замещенные конденсированные производные имидазола, фармацевтические композиции и способы их применения
US8759535B2 (en) 2010-02-18 2014-06-24 High Point Pharmaceuticals, Llc Substituted fused imidazole derivatives, pharmaceutical compositions, and methods of use thereof
WO2012145446A1 (en) * 2011-04-22 2012-10-26 Merck Sharp & Dohme Corp. Taste-masked formulations of raltegravir
WO2014194519A1 (en) 2013-06-07 2014-12-11 Merck Sharp & Dohme Corp. Imidazole derivatives and methods of use thereof for improving pharmacokinetics of drug
CN104000824B (zh) * 2014-05-28 2016-07-06 中山大学 苯并五元杂环类化合物在制备抗hiv-1病毒药物中的应用
WO2016089648A1 (en) 2014-12-01 2016-06-09 Vtv Therapeutics Llc Bach 1 inhibitors in combination with nrf2 activators and pharmaceutical compositions thereof
CN105985356B (zh) * 2015-02-05 2018-06-22 四川大学 咪唑[2,1-b]噻唑衍生物及其制备方法和用途
RU2747431C2 (ru) 2015-12-22 2021-05-05 Кансера Аб Бициклические гидроксамовые кислоты, полезные в качестве ингибиторов активности деацетилазы гистонов млекопитающих
AR114136A1 (es) 2017-10-10 2020-07-29 Hoffmann La Roche Compuestos heterocíclicos

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003076413A1 (en) * 2002-03-12 2003-09-18 Tibotec Pharmaceuticals Ltd Broadspectrum substituted benzimidazole sulfonamide hiv protease inhibitors
WO2006108879A2 (en) * 2005-04-15 2006-10-19 Tibotec Pharmaceuticals Ltd. Use of a sulfonamide compound for improving the pharmacokinetics of a drug

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6037157A (en) 1995-06-29 2000-03-14 Abbott Laboratories Method for improving pharmacokinetics
AR037797A1 (es) 2001-12-12 2004-12-01 Tibotec Pharm Ltd Combinacion de inhibidores de proteasa dependientes del citocromo p450
CN101445493A (zh) * 2002-08-02 2009-06-03 泰博特克药品有限公司 广谱2-氨基-苯并噻唑磺酰胺类hiv蛋白酶抑制剂
CN101674822A (zh) * 2006-08-18 2010-03-17 塞阔伊亚药品公司 抑制细胞色素p450的组合物和方法

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003076413A1 (en) * 2002-03-12 2003-09-18 Tibotec Pharmaceuticals Ltd Broadspectrum substituted benzimidazole sulfonamide hiv protease inhibitors
WO2006108879A2 (en) * 2005-04-15 2006-10-19 Tibotec Pharmaceuticals Ltd. Use of a sulfonamide compound for improving the pharmacokinetics of a drug

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
PATANI G A ET AL: "BIOISOSTERISM: A RATIONAL APPROACH IN DRUG DESIGN" CHEMICAL REVIEWS, ACS,WASHINGTON, DC, US, vol. 96, no. 8, 1 January 1996 (1996-01-01), pages 3147-3176, XP000652176 ISSN: 0009-2665 *

Also Published As

Publication number Publication date
EA019616B1 (ru) 2014-05-30
KR101624675B1 (ko) 2016-05-27
JP2011506291A (ja) 2011-03-03
CN101878210B (zh) 2013-07-17
US8350048B2 (en) 2013-01-08
TW200938540A (en) 2009-09-16
CN101878210A (zh) 2010-11-03
CL2008003639A1 (es) 2010-01-15
PE20091263A1 (es) 2009-08-14
IL205489A0 (en) 2010-12-30
WO2009071650A2 (en) 2009-06-11
EP2235008A2 (en) 2010-10-06
ZA201004025B (en) 2011-12-28
EA201070691A1 (ru) 2010-10-29
BRPI0821021A2 (pt) 2015-06-16
PA8806801A1 (es) 2009-07-23
UA103013C2 (uk) 2013-09-10
CA2706155C (en) 2016-07-19
KR20100092489A (ko) 2010-08-20
MX2010006166A (es) 2010-10-05
AU2008333165A1 (en) 2009-06-11
AU2008333165B2 (en) 2013-04-11
AP2010005285A0 (en) 2010-06-30
IL205489A (he) 2016-09-29
WO2009071650A3 (en) 2009-09-11
TWI438202B (zh) 2014-05-21
JP5509092B2 (ja) 2014-06-04
NZ585652A (en) 2011-10-28
EP2235008B1 (en) 2016-03-16
HK1149553A1 (en) 2011-10-07
CA2706155A1 (en) 2009-06-11
UY31513A1 (es) 2009-07-17
US20100305073A1 (en) 2010-12-02
AR069595A1 (es) 2010-02-03
MY151005A (en) 2014-03-31

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