AP2007004251A0 - A method for production of a bioengineered form oftissue plasminogen activator - Google Patents

A method for production of a bioengineered form oftissue plasminogen activator

Info

Publication number
AP2007004251A0
AP2007004251A0 AP2007004251A AP2007004251A AP2007004251A0 AP 2007004251 A0 AP2007004251 A0 AP 2007004251A0 AP 2007004251 A AP2007004251 A AP 2007004251A AP 2007004251 A AP2007004251 A AP 2007004251A AP 2007004251 A0 AP2007004251 A0 AP 2007004251A0
Authority
AP
ARIPO
Prior art keywords
oftissue
production
plasminogen activator
bioengineered
bioengineered form
Prior art date
Application number
AP2007004251A
Other languages
English (en)
Inventor
Villoo Morawala Patell
Original Assignee
Avestha Gengraine Tech Pvt Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Avestha Gengraine Tech Pvt Ltd filed Critical Avestha Gengraine Tech Pvt Ltd
Priority claimed from IN673CH2005 external-priority patent/IN2005CH00673A/en
Publication of AP2007004251A0 publication Critical patent/AP2007004251A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6456—Plasminogen activators
    • C12N9/6459—Plasminogen activators t-plasminogen activator (3.4.21.68), i.e. tPA
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6456—Plasminogen activators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67—General methods for enhancing the expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21069—Protein C activated (3.4.21.69)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AP2007004251A 2005-06-02 2006-05-31 A method for production of a bioengineered form oftissue plasminogen activator AP2007004251A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN673CH2005 IN2005CH00673A (ja) 2002-10-24 2006-05-31
PCT/IB2006/001481 WO2006129191A2 (en) 2005-06-02 2006-05-31 A method for optimized production of a recombinant form of tissue plasminogen activator

Publications (1)

Publication Number Publication Date
AP2007004251A0 true AP2007004251A0 (en) 2007-12-31

Family

ID=37482032

Family Applications (1)

Application Number Title Priority Date Filing Date
AP2007004251A AP2007004251A0 (en) 2005-06-02 2006-05-31 A method for production of a bioengineered form oftissue plasminogen activator

Country Status (14)

Country Link
US (1) US20090246188A1 (ja)
EP (1) EP1891214A2 (ja)
JP (1) JP2009507467A (ja)
KR (1) KR20080036561A (ja)
CN (1) CN101218344A (ja)
AP (1) AP2007004251A0 (ja)
AU (1) AU2006253855A1 (ja)
BR (1) BRPI0610958A2 (ja)
CA (1) CA2610391A1 (ja)
IL (1) IL187401A0 (ja)
MX (1) MX2007015091A (ja)
RU (1) RU2007147921A (ja)
WO (1) WO2006129191A2 (ja)
ZA (1) ZA200711008B (ja)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102199587B (zh) * 2011-03-24 2013-06-19 广东药学院 人纤溶酶原功能性突变体及其制备方法和应用
CN112111475B (zh) * 2020-09-24 2021-07-20 江苏丰华生物制药有限公司 一种经上皮细胞转运能力增强的TNK-tPA融合蛋白及其应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3559559B2 (ja) * 1992-06-03 2004-09-02 ジェネンテク，インコーポレイテッド 向上した治療特性を有する組織プラスミノーゲン活性化因子グリコシル化変異体

Also Published As

Publication number Publication date
CA2610391A1 (en) 2006-12-07
BRPI0610958A2 (pt) 2010-08-03
AU2006253855A1 (en) 2006-12-07
IL187401A0 (en) 2008-02-09
WO2006129191A3 (en) 2007-04-26
ZA200711008B (en) 2008-10-29
US20090246188A1 (en) 2009-10-01
CN101218344A (zh) 2008-07-09
KR20080036561A (ko) 2008-04-28
WO2006129191A2 (en) 2006-12-07
EP1891214A2 (en) 2008-02-27
MX2007015091A (es) 2008-03-11
JP2009507467A (ja) 2009-02-26
RU2007147921A (ru) 2009-07-20

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