AP1930A - Alpha crystalline form of strontium ranelate, a process for its preparation and pharmaceutical compositions containing it - Google Patents

Alpha crystalline form of strontium ranelate, a process for its preparation and pharmaceutical compositions containing it

Info

Publication number
AP1930A
AP1930A AP2005003323A AP2005003323A AP1930A AP 1930 A AP1930 A AP 1930A AP 2005003323 A AP2005003323 A AP 2005003323A AP 2005003323 A AP2005003323 A AP 2005003323A AP 1930 A AP1930 A AP 1930A
Authority
AP
ARIPO
Prior art keywords
preparation
pharmaceutical compositions
crystalline form
compositions containing
strontium ranelate
Prior art date
Application number
AP2005003323A
Other languages
English (en)
Other versions
AP2005003323A0 (en
Inventor
Stephanie Horvath
Isabelle Demuynck
Gerard Damien
Original Assignee
Servier Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34942420&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AP1930(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Servier Lab filed Critical Servier Lab
Publication of AP2005003323A0 publication Critical patent/AP2005003323A0/xx
Application granted granted Critical
Publication of AP1930A publication Critical patent/AP1930A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Fodder In General (AREA)
  • Steroid Compounds (AREA)
AP2005003323A 2004-09-30 2005-05-31 Alpha crystalline form of strontium ranelate, a process for its preparation and pharmaceutical compositions containing it AP1930A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0410335A FR2875807B1 (fr) 2004-09-30 2004-09-30 Forme cristalline alpha du ranelate de strontium, son procede de preparation, et les compositions pharmaceutiques qui la contiennent

Publications (2)

Publication Number Publication Date
AP2005003323A0 AP2005003323A0 (en) 2005-06-30
AP1930A true AP1930A (en) 2008-12-15

Family

ID=34942420

Family Applications (1)

Application Number Title Priority Date Filing Date
AP2005003323A AP1930A (en) 2004-09-30 2005-05-31 Alpha crystalline form of strontium ranelate, a process for its preparation and pharmaceutical compositions containing it

Country Status (41)

Country Link
US (2) US7459568B2 (de)
EP (2) EP1944302A1 (de)
JP (2) JP2006104184A (de)
KR (1) KR100816590B1 (de)
CN (1) CN100391956C (de)
AP (1) AP1930A (de)
AR (1) AR049395A1 (de)
AT (1) ATE411308T1 (de)
AU (1) AU2005202718B2 (de)
BR (1) BRPI0502228A (de)
CA (1) CA2508824C (de)
CO (1) CO5710195A1 (de)
CR (1) CR7876A (de)
CY (1) CY1108797T1 (de)
DE (1) DE602005010359D1 (de)
DK (1) DK1642897T3 (de)
EA (1) EA008474B1 (de)
EC (1) ECSP055859A (de)
ES (1) ES2314593T3 (de)
FR (1) FR2875807B1 (de)
GE (1) GEP20074106B (de)
GT (1) GT200500130A (de)
HR (1) HRP20080652T3 (de)
IL (1) IL169237A (de)
MA (1) MA27815A1 (de)
MX (1) MXPA05006407A (de)
NO (1) NO333948B1 (de)
NZ (1) NZ540802A (de)
OA (1) OA13013A (de)
PA (1) PA8638201A1 (de)
PE (1) PE20060364A1 (de)
PL (1) PL1642897T3 (de)
PT (1) PT1642897E (de)
RS (1) RS51110B (de)
SA (1) SA05260168B1 (de)
SG (1) SG121035A1 (de)
SI (1) SI1642897T1 (de)
TW (1) TWI367881B (de)
UA (1) UA80008C2 (de)
WO (1) WO2006035122A1 (de)
ZA (1) ZA200504937B (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2875807B1 (fr) * 2004-09-30 2006-11-17 Servier Lab Forme cristalline alpha du ranelate de strontium, son procede de preparation, et les compositions pharmaceutiques qui la contiennent
US20070292535A1 (en) * 2006-06-19 2007-12-20 Tabbiner Philip S Strontium compositions and methods of treating arthritic and or osteoporitic conditions
US20070292529A1 (en) * 2006-06-19 2007-12-20 Tabbiner Philip S Strontium compositions and methods of treating osteoporotic conditions
CN101206208B (zh) * 2006-12-19 2011-08-10 北京德众万全药物技术开发有限公司 一种用hplc法分析雷尼酸锶原料及其制剂的方法
KR20110066197A (ko) 2008-09-29 2011-06-16 라티오팜 게엠베하 스트론튬 라넬레이트의 무수물 및 수화물 형태
IT1398542B1 (it) 2010-03-05 2013-03-01 Chemelectiva S R L Processo per la preparazione di un polimorfo
CN102241663B (zh) * 2010-05-10 2013-02-13 山东方明药业集团股份有限公司 一种雷奈酸锶八水合物的制备方法
WO2012143932A1 (en) * 2011-04-21 2012-10-26 Shilpa Medicare Limited Crystalline strontium ranelate form-s
CZ2011320A3 (cs) 2011-05-30 2012-12-12 Zentiva, K.S. Stabilní krystalická forma X stroncium ranelátu
EP2530068A1 (de) 2011-05-31 2012-12-05 Lacer, S.A. Neue Strontiumsalze, deren Synthese und Verwendung bei der Behandlung von Osteoporose
WO2013013003A1 (en) 2011-07-21 2013-01-24 Emory University Methods for treating inflamatory conditions and states, and cancers by antagonizing nf-kb activation
CN102503931A (zh) * 2011-09-20 2012-06-20 浙江华海药业股份有限公司 一种雷尼酸锶晶形h的制备方法
WO2013113319A1 (en) * 2012-01-31 2013-08-08 Pharmathen S.A. Process for the preparation of strontium ranelate, intermediate or hydrates thereof
EP2641905A1 (de) 2012-03-23 2013-09-25 Urquima S.A. Feste Formen von Strontiumranelat und Verfahren zu ihrer Herstellung
US8569514B1 (en) 2012-05-17 2013-10-29 Divi's Laboratories, Ltd. Process for the preparation of strontium ranelate

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0415850A1 (de) * 1989-09-01 1991-03-06 Adir Et Compagnie Zweiwertige Metallsalze von 2-N,N-di(carboxymethyl)amino,3-cyano,4-carboxymethyl,5-carboxy-thiophensäure, Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Zusammensetzungen
EP0813869A1 (de) * 1996-06-17 1997-12-29 Adir Et Compagnie Verwendung von Strontiumsälze zur Behandlung von Arthrose
WO2004029036A1 (fr) * 2002-09-24 2004-04-08 Les Laboratoires Servier Nouveau procede de synthese industriel du ranelate de strontium et de ses hydrates

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW398975B (en) 1994-07-22 2000-07-21 Lilly Co Eli Pharmaceutical composition for inhibiting bone loss
DE19642451A1 (de) 1996-10-15 1998-04-16 Merck Patent Gmbh Aminothiophencarbonsäureamide
EP1451194B2 (de) * 2001-10-03 2009-12-16 Teva Pharmaceutical Industries Ltd. Herstellung von levofloxacin hemihydrat
CA2471144C (en) * 2002-01-09 2011-06-07 Emisphere Technologies, Inc. Polymorphs of sodium 4-[(4-chloro-2-hydroxybenzoyl)amino]butanoate
US7396839B2 (en) * 2002-08-06 2008-07-08 Teva Pharmaceuticals Usa, Inc. Crystalline forms of gatifloxacin
FR2844796A1 (fr) * 2002-09-24 2004-03-26 Servier Lab Nouveau procede de synthese industrielle du diester methylique de l'acide 5-amino-3-carboxymethyl-4-cyano-2- thiophenecarboxylique, et application a la synthese des sels bivalents de l'acide ranelique et de leurs hydrates
FR2844797B1 (fr) * 2002-09-24 2004-10-22 Servier Lab Nouveau procede de synthese industriel des tetraesters de l'acide 5-[bis (carboxymethyl)]-3-carboxymethyl-4-cyano-2- thiophenecarboxylique, et application a la synthese des sels bivalents de l'acide ranelique et de leurs hydrates
FR2875807B1 (fr) * 2004-09-30 2006-11-17 Servier Lab Forme cristalline alpha du ranelate de strontium, son procede de preparation, et les compositions pharmaceutiques qui la contiennent

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0415850A1 (de) * 1989-09-01 1991-03-06 Adir Et Compagnie Zweiwertige Metallsalze von 2-N,N-di(carboxymethyl)amino,3-cyano,4-carboxymethyl,5-carboxy-thiophensäure, Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Zusammensetzungen
EP0813869A1 (de) * 1996-06-17 1997-12-29 Adir Et Compagnie Verwendung von Strontiumsälze zur Behandlung von Arthrose
WO2004029036A1 (fr) * 2002-09-24 2004-04-08 Les Laboratoires Servier Nouveau procede de synthese industriel du ranelate de strontium et de ses hydrates

Also Published As

Publication number Publication date
NO20052998D0 (no) 2005-06-17
AU2005202718B2 (en) 2010-09-16
GT200500130A (es) 2005-12-20
ZA200504937B (en) 2006-04-26
FR2875807A1 (fr) 2006-03-31
MXPA05006407A (es) 2006-04-05
KR20060049966A (ko) 2006-05-19
EA008474B1 (ru) 2007-06-29
JP2010132669A (ja) 2010-06-17
PT1642897E (pt) 2008-11-27
PL1642897T3 (pl) 2009-04-30
ECSP055859A (es) 2006-09-18
NO333948B1 (no) 2013-10-28
AP2005003323A0 (en) 2005-06-30
EP1642897B1 (de) 2008-10-15
SG121035A1 (en) 2006-04-26
EP1642897A1 (de) 2006-04-05
GEP20074106B (en) 2007-05-10
ATE411308T1 (de) 2008-10-15
DE602005010359D1 (de) 2008-11-27
NZ540802A (en) 2006-11-30
AR049395A1 (es) 2006-07-26
CA2508824A1 (fr) 2006-03-30
IL169237A (en) 2010-12-30
FR2875807B1 (fr) 2006-11-17
DK1642897T3 (da) 2009-01-26
CA2508824C (fr) 2009-03-24
SA05260168B1 (ar) 2009-02-25
TW200610758A (en) 2006-04-01
WO2006035122A1 (fr) 2006-04-06
UA80008C2 (uk) 2007-08-10
CN1754878A (zh) 2006-04-05
HRP20080652T3 (en) 2009-01-31
CR7876A (es) 2007-12-10
CN100391956C (zh) 2008-06-04
SI1642897T1 (sl) 2009-02-28
PE20060364A1 (es) 2006-06-17
MA27815A1 (fr) 2006-04-03
US20080312314A1 (en) 2008-12-18
US7745482B2 (en) 2010-06-29
EA200500842A1 (ru) 2006-04-28
EP1944302A1 (de) 2008-07-16
EP1642897B9 (de) 2009-08-12
CY1108797T1 (el) 2014-04-09
JP2006104184A (ja) 2006-04-20
OA13013A (fr) 2006-11-10
NO20052998L (no) 2006-03-31
BRPI0502228A (pt) 2006-05-09
TWI367881B (en) 2012-07-11
RS51110B (sr) 2010-10-31
US20060069271A1 (en) 2006-03-30
ES2314593T3 (es) 2009-03-16
KR100816590B1 (ko) 2008-03-24
US7459568B2 (en) 2008-12-02
HK1086260A1 (zh) 2006-09-15
AU2005202718A1 (en) 2006-04-13
PA8638201A1 (es) 2006-05-16
CO5710195A1 (es) 2006-12-29

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