SG11201808915YA - Chagas antigens and antibodies and compositions, methods and uses thereof - Google Patents

Abstract

INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) REVISED VERSION --, (19) World Intellectual Property Organization 1111111011111111101 111111111101011101110101H111111111111111111111111110111111111111 International Bureau (10) International Publication Number l i (43) International Publication Date ...../ WO 2017/178660 A9 19 October 2017 (19.10.2017) WIPO I PCT (51) International Patent Classification: AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, A61K 39/005 (2006.01) C07K 14/44 (2006.01) CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, (21) International Application Number: DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, PCT/EP2017/059189 HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, (22) International Filing Date: MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, 18 April 2017 (18.04.2017) PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, (25) Filing Language: English TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (26) Publication Language: English (84) Designated States (unless otherwise indicated, for every (30) Priority Data: kind of regional protection available): ARIPO (BW, GH, 62/322,770 14 April 2016 (14.04.2016) US GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, (71) Applicant: PEPTCELL LIMITED [GB/GB]; 100 Fetter UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, Lane, London Greater London EC4A 1BN (GB). EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, (72) Inventors: PLEGUEZUELOS MATEO, Olga; c/o PepT- MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, cell Limited, 100 Fetter Lane, London Greater London TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, EC4A 1BN (GB). CAPARROS-WANDERLEY, Wilson, KM, ML, MR, NE, SN, TD, TG). Romero; c/o PepTcell Limited, 100 Fetter Lane, London Greater London EC4A 1BN (GB). STOLOFF, Grego- Declarations under Rule 4.17: ry, Alan; c/o PepTcell Limited, 100 Fetter Lane, London — as to applicant's entitlement to apply for and be granted a Greater London EC4A 1BN (GB). patent (Rule 4.1700) (74) Agent: SCHLICH; 9 St. Catherine's Road, Littlehampton West Sussex BN17 5HS (GB). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, (54) Title: CHAGAS ANTIGENS AND ANTIBODIES 100 80 60 Tv 3 40 • A AND COMPOSITIONS, METHODS AND USES THEREOF -a- A+C (control) -0- B D 20 01 0 5 10 15 20 25 30 35 40 45 50 0 Day (pi) IN pc Fig. 12 ,-, N (57) : The present specification discloses Trypanosoma antigens, immunogenic compositions and medicaments comprising 1-1 C such Trypanosoma antigens, methods and uses for such Trypanosoma antigensand immunogenic compositions for treating a Trypano so- ei ma-based disease. C [Continued on next page] WO 2017/178660 A9 IMEDIMOM0101011MOIDEMOMOINIDER011001101MEMHO# Published: — with international search report (Art. 21(3)) — before the expiration of the time limit for amending the claims and to be republished in the event of receipt of amendments (Rule 48.2(h)) — with sequence listing part of description (Rule 5.2(a)) (88) Date of publication of the revised international search report: 07 December 2017 (07.12.2017) (15) Information about Correction: see Notice of 07 December 2017 (07.12.2017)