SG11201908326YA - Methods of treating neurodegenerative diseases - Google Patents

Methods of treating neurodegenerative diseases

Info

Publication number
SG11201908326YA
SG11201908326YA SG11201908326YA SG11201908326YA SG 11201908326Y A SG11201908326Y A SG 11201908326YA SG 11201908326Y A SG11201908326Y A SG 11201908326YA SG 11201908326Y A SG11201908326Y A SG 11201908326YA
Authority
SG
Singapore
Prior art keywords
international
genentech
california
pct
san francisco
Prior art date
Application number
Inventor
Geoffrey Kerchner
Edmond Teng
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of SG11201908326YA publication Critical patent/SG11201908326YA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/567—Framework region [FR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Abstract

INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 04 October 2018 (04.10.2018) WIPO I PCT (51) International Patent Classification: C07K 16/18 (2006.01) A61K 39/00 (2006.01) (21) International Application Number: PCT/US2018/024300 (22) International Filing Date: ill 1111u°11111VIIIVIIII o monii mina° oimIE (10) International Publication Number WO 2018/183175 Al (25) Filing Language: (26) Publication Language: (30) Priority Data: 62/477,535 62/532,696 62/577,559 62/580,359 26 March 2018 (26.03.2018) English English 28 March 2017 (28.03.2017) US 14 July 2017 (14.07.2017) US 26 October 2017 (26.10.2017) US 01 November 2017 (01.11.2017) US (71) Applicant: GENENTECH, INC. [US/US]; 1 DNA Way, South San Francisco, California 94080 (US). (72) Inventors: KERCHNER, Geoffrey; c/o Genentech, Inc., 1 DNA Way, South San Francisco, California 94080 (US). TENG, Edmond; c/o Genentech, Inc., 1 DNA Way, South San Francisco, California 94080 (US). (74) Agent: SCARR, Rebecca B. et al.; 500 W. Silver Spring Drive, Suite K-200, Glendale, Wisconsin 53217 (US). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Published: with international search report (Art. 21(3)) N with sequence listing part of description (Rule 5.2(a)) 00 1-1 O C \" (57) : The invention provides methods of treating tauopathies with anti-Tau antibodies. (54) Title: METHODS OF TREATING NEURODEGENERATIVE DISEASES
SG11201908326Y 2017-03-28 2018-03-26 Methods of treating neurodegenerative diseases SG11201908326YA (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201762477535P 2017-03-28 2017-03-28
US201762532696P 2017-07-14 2017-07-14
US201762577559P 2017-10-26 2017-10-26
US201762580359P 2017-11-01 2017-11-01
PCT/US2018/024300 WO2018183175A1 (en) 2017-03-28 2018-03-26 Methods of treating neurodegenerative diseases

Publications (1)

Publication Number Publication Date
SG11201908326YA true SG11201908326YA (en) 2019-10-30

Family

ID=62063590

Family Applications (2)

Application Number Title Priority Date Filing Date
SG11201908326Y SG11201908326YA (en) 2017-03-28 2018-03-26 Methods of treating neurodegenerative diseases
SG10201911225WA SG10201911225WA (en) 2017-03-28 2018-03-26 Methods of treating neurodegenerative diseases

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG10201911225WA SG10201911225WA (en) 2017-03-28 2018-03-26 Methods of treating neurodegenerative diseases

Country Status (13)

Country Link
US (2) US20200131255A1 (en)
EP (1) EP3601337A1 (en)
JP (2) JP2020515543A (en)
KR (1) KR20190133162A (en)
CN (2) CN110494446A (en)
AU (1) AU2018244224A1 (en)
CA (1) CA3055758A1 (en)
IL (1) IL269106A (en)
MA (1) MA48996A (en)
MX (1) MX2019011423A (en)
SG (2) SG11201908326YA (en)
TW (2) TW201836640A (en)
WO (1) WO2018183175A1 (en)

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KR102506091B1 (en) 2016-05-02 2023-03-07 프로테나 바이오사이언시즈 리미티드 Tau Immunotherapy
CU24537B1 (en) 2016-05-02 2021-07-02 Prothena Biosciences Ltd MONOCLONAL ANTIBODIES COMPETING TO JOIN HUMAN TAU WITH THE 3D6 ANTIBODY
KR20230146126A (en) 2016-12-07 2023-10-18 제넨테크, 인크. Anti-tau antibodies and methods of use
CN110248959B (en) 2016-12-07 2023-06-30 基因泰克公司 anti-TAU antibodies and methods of use
CN110520440A (en) 2017-02-17 2019-11-29 戴纳立制药公司 Anti- τ antibody and its application method
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Also Published As

Publication number Publication date
MX2019011423A (en) 2019-11-01
SG10201911225WA (en) 2020-01-30
TW201836640A (en) 2018-10-16
RU2019130976A3 (en) 2021-09-13
CA3055758A1 (en) 2018-10-04
US20210284720A1 (en) 2021-09-16
JP2023055720A (en) 2023-04-18
EP3601337A1 (en) 2020-02-05
TW202400231A (en) 2024-01-01
CN117205311A (en) 2023-12-12
US20200131255A1 (en) 2020-04-30
KR20190133162A (en) 2019-12-02
CN110494446A (en) 2019-11-22
MA48996A (en) 2020-02-05
RU2019130976A (en) 2021-04-28
JP2020515543A (en) 2020-05-28
AU2018244224A1 (en) 2019-09-19
WO2018183175A1 (en) 2018-10-04
IL269106A (en) 2019-11-28

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