MX366972B - Metodos y composiciones para caracterizar imagenes medicas en forma objetiva. - Google Patents

Metodos y composiciones para caracterizar imagenes medicas en forma objetiva.

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Publication number
MX366972B
MX366972B MX2014003621A MX2014003621A MX366972B MX 366972 B MX366972 B MX 366972B MX 2014003621 A MX2014003621 A MX 2014003621A MX 2014003621 A MX2014003621 A MX 2014003621A MX 366972 B MX366972 B MX 366972B
Authority
MX
Mexico
Prior art keywords
compositions
methods
patient
objectively characterizing
medical images
Prior art date
Application number
MX2014003621A
Other languages
English (en)
Other versions
MX2014003621A (es
Inventor
Starosolski Zbigniew
Original Assignee
Ananth Annapragada
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ananth Annapragada filed Critical Ananth Annapragada
Publication of MX2014003621A publication Critical patent/MX2014003621A/es
Publication of MX366972B publication Critical patent/MX366972B/es

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    • A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/52—Devices using data or image processing specially adapted for radiation diagnosis
    • A61B6/5211—Devices using data or image processing specially adapted for radiation diagnosis involving processing of medical diagnostic data
    • A61B6/5229—Devices using data or image processing specially adapted for radiation diagnosis involving processing of medical diagnostic data combining image data of a patient, e.g. combining a functional image with an anatomical image
    • A61B6/5247—Devices using data or image processing specially adapted for radiation diagnosis involving processing of medical diagnostic data combining image data of a patient, e.g. combining a functional image with an anatomical image combining images from an ionising-radiation diagnostic technique and a non-ionising radiation diagnostic technique, e.g. X-ray and ultrasound
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    • A61B5/0033—Features or image-related aspects of imaging apparatus classified in A61B5/00, e.g. for MRI, optical tomography or impedance tomography apparatus; arrangements of imaging apparatus in a room
    • A61B5/0035—Features or image-related aspects of imaging apparatus classified in A61B5/00, e.g. for MRI, optical tomography or impedance tomography apparatus; arrangements of imaging apparatus in a room adapted for acquisition of images from more than one imaging mode, e.g. combining MRI and optical tomography
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    • A61B5/004—Features or image-related aspects of imaging apparatus classified in A61B5/00, e.g. for MRI, optical tomography or impedance tomography apparatus; arrangements of imaging apparatus in a room adapted for image acquisition of a particular organ or body part
    • A61B5/0042—Features or image-related aspects of imaging apparatus classified in A61B5/00, e.g. for MRI, optical tomography or impedance tomography apparatus; arrangements of imaging apparatus in a room adapted for image acquisition of a particular organ or body part for the brain
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    • A61B5/055—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves  involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
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    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10—Organic compounds
    • A61K49/101—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals
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    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10—Organic compounds
    • A61K49/12—Macromolecular compounds
    • A61K49/126—Linear polymers, e.g. dextran, inulin, PEG
    • A61K49/128—Linear polymers, e.g. dextran, inulin, PEG comprising multiple complex or complex-forming groups, being either part of the linear polymeric backbone or being pending groups covalently linked to the linear polymeric backbone
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    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
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    • A61K49/143—Peptides, e.g. proteins the protein being an albumin, e.g. HSA, BSA, ovalbumin
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    • A61K49/1806—Suspensions, emulsions, colloids, dispersions
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    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/007—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests for contrast media
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
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    • G01R33/48—NMR imaging systems
    • G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
    • G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
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    • G06T7/35—Determination of transform parameters for the alignment of images, i.e. image registration using statistical methods
    • G—PHYSICS
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    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/30—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indices; for individual health risk assessment
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    • A61B6/02—Arrangements for diagnosis sequentially in different planes; Stereoscopic radiation diagnosis
    • A61B6/03—Computed tomography [CT]
    • A61B6/032—Transmission computed tomography [CT]
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    • A61B6/50—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment specially adapted for specific body parts; specially adapted for specific clinical applications
    • A61B6/501—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment specially adapted for specific body parts; specially adapted for specific clinical applications for diagnosis of the head, e.g. neuroimaging or craniography
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    • G06T2207/30—Subject of image; Context of image processing
    • G06T2207/30004—Biomedical image processing
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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medical Informatics (AREA)
  • Radiology & Medical Imaging (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • Surgery (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Chemical & Material Sciences (AREA)
  • High Energy & Nuclear Physics (AREA)
  • General Physics & Mathematics (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Optics & Photonics (AREA)
  • Theoretical Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Physiology (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • Neurosurgery (AREA)
  • Psychology (AREA)
  • Dispersion Chemistry (AREA)
  • Nanotechnology (AREA)
  • Quality & Reliability (AREA)
  • Immunology (AREA)
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  • Hospice & Palliative Care (AREA)
  • Child & Adolescent Psychology (AREA)
  • Psychiatry (AREA)
  • Vascular Medicine (AREA)
  • Anesthesiology (AREA)

Abstract

Se proporcionan métodos y composiciones para caracterizar objetivamente una lesión patológica en un paciente. El método comprende: introducir en el paciente un agente potenciador de contraste; someter al paciente a formación de imágenes por resonancia magnética para obtener una imagen; y aplicar una función de autocorrelación 3-D a un subdominio de interés de la imagen para obtener por lo menos un espectro de autocorrelación 3-D. El método además puede comprender comparar el o los espectros de autocorrelación 3-D con un espectro de autocorrelación 3-D preexistente que es característico para la lesión patológica. En un ejemplo, los métodos y composiciones pueden ser útiles para identificar y caracterizar objetivamente depósitos de placas amiloideas característicos de la enfermedad de Alzheimer.
MX2014003621A 2012-01-20 2013-01-20 Metodos y composiciones para caracterizar imagenes medicas en forma objetiva. MX366972B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261589165P 2012-01-20 2012-01-20
PCT/US2013/022336 WO2013110013A1 (en) 2012-01-20 2013-01-20 Methods and compositions for objectively characterizing medical images

Publications (2)

Publication Number Publication Date
MX2014003621A MX2014003621A (es) 2014-08-22
MX366972B true MX366972B (es) 2019-08-01

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US (1) US10130326B2 (es)
EP (1) EP2756459B1 (es)
JP (1) JP6130401B2 (es)
KR (1) KR102064398B1 (es)
CN (1) CN104081416B (es)
AU (1) AU2013209437B2 (es)
BR (1) BR112014010879A2 (es)
CA (1) CA2848994A1 (es)
ES (1) ES2855165T3 (es)
HK (1) HK1202176A1 (es)
MX (1) MX366972B (es)
WO (1) WO2013110013A1 (es)

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