JPS5777624A - Adsorbent for rheumatoid factor and apparatus for removing rheumatoid factor - Google Patents
Adsorbent for rheumatoid factor and apparatus for removing rheumatoid factorInfo
- Publication number
- JPS5777624A JPS5777624A JP55152183A JP15218380A JPS5777624A JP S5777624 A JPS5777624 A JP S5777624A JP 55152183 A JP55152183 A JP 55152183A JP 15218380 A JP15218380 A JP 15218380A JP S5777624 A JPS5777624 A JP S5777624A
- Authority
- JP
- Japan
- Prior art keywords
- rheumatoid factor
- adsorbent
- fluid
- denaturated
- immunoglobulin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Abstract
PURPOSE: To provide a rheumatoid factor adsorbent containing, as an active component, immunoglobulin G denaturated by contacting with an organic solvent, and to provide a safe and sure treating apparatus for collagen disease, composed of a container having an inlet and an outlet of fluid and containing said adsorbent.
CONSTITUTION: Denaturated substance containing immunoglobulin G can be obtained by contacting and denaturating an immunoglobulin G-containing substance with an organic solvent such as formamide, acetamide, etc. The objective adsorbent for rheumatoid factor is prepared pref. by crosslinking and insolubilizing the denaturated substance. The adsorbent is packed in a container having an inlet and an outlet of fluid to obtain the rheumatoid factor removing apparatus. By passing the body fluid (blood, plasma, etc.) of a patient of collagen disease through the apparatus, and returning the cleaned blood fluid to the patient, the rheumatoid factor which is supposed to a cause of the disease can be removed, and the treatment of collagen disease can be carried out with simple method.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP55152183A JPS5777624A (en) | 1980-10-31 | 1980-10-31 | Adsorbent for rheumatoid factor and apparatus for removing rheumatoid factor |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP55152183A JPS5777624A (en) | 1980-10-31 | 1980-10-31 | Adsorbent for rheumatoid factor and apparatus for removing rheumatoid factor |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS5777624A true JPS5777624A (en) | 1982-05-15 |
Family
ID=15534863
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP55152183A Pending JPS5777624A (en) | 1980-10-31 | 1980-10-31 | Adsorbent for rheumatoid factor and apparatus for removing rheumatoid factor |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5777624A (en) |
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5940862A (en) * | 1982-08-30 | 1984-03-06 | テルモ株式会社 | Rheumatoid factor adsorbent and production thereof |
JPS59141524A (en) * | 1983-02-03 | 1984-08-14 | Terumo Corp | Antibody adsorbent |
US4705628A (en) * | 1985-04-09 | 1987-11-10 | Terumo Kabushiki Kaisha | Immunoglobulin adsorbent and adsorption apparatus |
JPS63212369A (en) * | 1986-11-21 | 1988-09-05 | イムレ コーポレイション | Antigen specific removal of recirculation immune complex |
US5782792A (en) * | 1986-11-21 | 1998-07-21 | Cypress Bioscience, Inc. | Method for treatment of rheumatoid arthritis |
CN109342743A (en) * | 2018-12-05 | 2019-02-15 | 菲鹏生物股份有限公司 | A kind of preparation method for the denaturation IgG that can be efficiently combined with rheumatoid factor |
-
1980
- 1980-10-31 JP JP55152183A patent/JPS5777624A/en active Pending
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5940862A (en) * | 1982-08-30 | 1984-03-06 | テルモ株式会社 | Rheumatoid factor adsorbent and production thereof |
JPS59141524A (en) * | 1983-02-03 | 1984-08-14 | Terumo Corp | Antibody adsorbent |
US4705628A (en) * | 1985-04-09 | 1987-11-10 | Terumo Kabushiki Kaisha | Immunoglobulin adsorbent and adsorption apparatus |
JPS63212369A (en) * | 1986-11-21 | 1988-09-05 | イムレ コーポレイション | Antigen specific removal of recirculation immune complex |
US5782792A (en) * | 1986-11-21 | 1998-07-21 | Cypress Bioscience, Inc. | Method for treatment of rheumatoid arthritis |
CN109342743A (en) * | 2018-12-05 | 2019-02-15 | 菲鹏生物股份有限公司 | A kind of preparation method for the denaturation IgG that can be efficiently combined with rheumatoid factor |
CN109342743B (en) * | 2018-12-05 | 2022-02-18 | 菲鹏生物股份有限公司 | Preparation method of denatured IgG capable of being efficiently combined with rheumatoid factor |
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