JP2015051227A - Display device, display method, and control program for display device - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide a display device for mitigating a burden on a medical worker such as an anesthesiologist.SOLUTION: A first signal reception unit 21 receives a first signal corresponding to a pharmacological agent dosage state of at least one of a muscle relaxant and antagonist to a subject. A second signal reception unit 22 receives a second signal corresponding to a first reaction of a muscle of the subject in response to a first electric stimulus. A kinetic calculation unit 31 acquires a pharmacokinetic property of a pharmacological agent by calculation, on the basis of the first signal. A first display control unit 41 makes a trend of the dosage state be displayed in a first area 11 on a display screen 10, on the basis of the first signal. A second display control unit 42 makes a trend of the pharmacokinetic property be displayed in a second area 12. A third display control unit 43 makes a trend of the first reaction be displayed in a third area 13, on the basis of the second signal. The first display control unit 41, the second display control unit 42, and the third display control unit 43 make the trend of the dosage state, trend of the pharmacokinetic property, and trend of the first reaction be displayed on the display screen 10 in temporally synchronized states.

Description

  The present invention relates to a display device for muscle relaxation information, a method for displaying muscle relaxation information, and a program for controlling a display device for muscle relaxation information.

  Patent Document 1 discloses an apparatus for monitoring muscle relaxation information of a subject in order to determine an appropriate dose and timing of administration of a muscle relaxant used when performing general anesthesia. According to the apparatus, it is possible to acquire and display a trend of a response to an electrical stimulus given to a subject's muscle.

Japanese Patent Laid-Open No. 10-57320

  When general anesthesia is performed, administration history of drugs such as muscle relaxants and antagonists, biological information of a subject acquired through a biological signal monitor, and the like are recorded through an electronic anesthesia recording system. The subject response trend provided by the muscle relaxation information monitoring device is generally provided through a dedicated screen different from the information display screen provided by the electronic anesthesia recording system. Medical personnel such as anesthesiologists are forced to perform a complicated task of comparing and examining information provided through another screen when determining an appropriate dose and timing of administration of a drug according to the depth of anesthesia.

  Therefore, an object of the present invention is to provide a technique for reducing the burden on medical personnel such as anesthesiologists.

In order to achieve the above object, a first aspect of the present invention is a display device for muscle relaxation information,
A display screen;
A first signal receiving unit for receiving a first signal corresponding to an administration state of at least one of a muscle relaxant and an antagonist for a subject;
A second signal receiving unit that receives a second signal corresponding to a first response of the subject's muscle to a first electrical stimulus;
Based on the first signal, a kinetic calculator that acquires the pharmacokinetics of the drug by calculation;
A first display control unit configured to display a trend of the administration state in a first region of the display screen based on the first signal;
A second display control unit for displaying the pharmacokinetic trend in a second region of the display screen;
A third display control unit configured to display a trend of the first reaction in a third region of the display screen based on the second signal;
The first display control unit, the second display control unit, and the third display control unit are time-synchronized with the administration state trend, the pharmacokinetic trend, and the first reaction trend. In the state, it is displayed on the display screen.

In order to achieve the above object, a second aspect of the present invention is a method for displaying muscle relaxation information,
A trend of administration state of at least one of a muscle relaxant and an antagonist is displayed in the first area of the display screen,
The pharmacokinetic trend of the drug obtained by calculation is displayed in the second area of the display screen,
The trend of the first response of the subject's muscle to the first electrical stimulation is displayed in the third area of the display screen,
The administration state trend, the pharmacokinetic trend, and the first reaction trend are displayed on the display screen in a time-synchronized state.

In order to achieve the above object, a third aspect that the present invention can take is a program for controlling a display device for muscle relaxation information,
The display device includes a display screen and a computer connected to the display screen,
The program causes the computer to
A first signal receiving unit for receiving a first signal corresponding to the administration state of at least one of the muscle relaxant and the antagonist;
A second signal receiving unit for receiving a second signal corresponding to the first reaction of the muscle of the subject to the first electrical stimulation;
Based on the first signal, a kinetic calculator that acquires the pharmacokinetics of the drug by calculation,
A first display control unit configured to display a trend of the administration state in a first region of the display screen based on the first signal;
A second display control section for displaying the pharmacokinetic trend in the second area of the display screen; and a third display for displaying the trend of the first reaction in the third area of the display screen based on the second signal. Operate as a display controller,
The first display control unit and the second display so that the administration state trend, the pharmacokinetic trend, and the first reaction trend are displayed on the display screen in a time-synchronized state. The control unit and the third display control unit are operated.

  According to such a configuration, since the trend of the drug administration state, the trend of the pharmacokinetics, and the trend of the first reaction are aggregated and displayed in a single display screen, a medical worker such as an anesthesiologist However, it is possible to eliminate the complexity of comparing these trend information provided through separate screens. Furthermore, since these trend information is displayed in a time-synchronized state, it is easy to intuitively understand the relationship between the trend information, and it is possible to determine the appropriate drug dose and administration timing according to the depth of anesthesia. It becomes easy. Therefore, the burden on medical personnel such as anesthesiologists can be reduced.

  A second signal receiving unit that receives a third signal corresponding to a second reaction of the muscle of the subject with respect to a second electrical stimulus stronger than the first electrical stimulus, and based on the third signal, the display It is good also as a structure provided with the 4th display control part which displays the trend of the said 2nd reaction in the 4th area | region of a screen. In this case, the fourth display control unit is configured such that the trend of the second response is temporally synchronized with the trend of the administration state, the trend of the pharmacokinetics, and the trend of the first response, Display on the display screen.

  According to such a configuration, in addition to the trend of the drug administration state, the trend of the pharmacokinetics, and the trend of the first response, the trend of the second response is displayed in a single display screen. A medical worker such as a doctor can eliminate the trouble of comparing these trend information provided through separate screens. The trend of the second response, which is muscle relaxation information in a state where the depth of anesthesia is deep, is displayed in a time-synchronized state with other trend information. Judgment of timing becomes more reliable. Therefore, the burden on medical personnel such as anesthesiologists can be reduced.

  An instruction input unit for inputting a user instruction may be provided, and the fourth display control unit may be configured to switch between display and non-display of the fourth region based on the instruction.

  According to such a configuration, the fourth region can appear on the display screen only when necessary. Under the situation where it is not necessary to display the trend of the second reaction, the visually recognized information can be minimized by switching the fourth region to the non-display state. As a result, medical personnel such as anesthesiologists can concentrate on necessary judgment work. Therefore, the burden on medical personnel such as anesthesiologists can be reduced.

  The first display control unit displays the administration state of the muscle relaxant on the first side of the time axis in the first region and displays the administration state of the antagonist on the second side of the time axis. It is good also as a structure.

  According to such a configuration, administration states of different types of drugs can be intuitively grasped without causing confusion. Therefore, the burden on medical personnel such as anesthesiologists can be reduced.

  Based on the pharmacokinetic trend and the trend of the first reaction, a dose calculation unit that obtains a sustained dose of the muscle relaxant by calculation, a dose output unit that outputs information indicating the sustained dose, It is good also as a structure provided with.

  According to such a configuration, based on the first muscle relaxant administration event, information indicating the continuous dose of the muscle relaxant in the subsequent muscle relaxant administration event is automatically provided. A medical worker such as an anesthesiologist can determine the continuous dose based on the information without depending on judgment based on experience and intuition. Therefore, the burden on medical personnel such as anesthesiologists can be reduced.

It is a block diagram which shows the structure of the display apparatus which concerns on one Embodiment of this invention. It is a figure which shows typically the structure of the display screen with which a display apparatus is provided. It is a figure which shows typically the structure of the display screen of the state which made the 4th area | region non-display. It is a figure which shows typically an example of the information displayed on the 1st area | region of a display screen.

  Exemplary embodiments of the present invention will be described in detail below with reference to the accompanying drawings.

  FIG. 1 is a block diagram showing a configuration of a display device 1 according to an embodiment of the present invention. The display device 1 is a device that displays muscle relaxation information. The display device 1 includes a display screen 10, a first signal receiving unit 21, a second signal receiving unit 22, a dynamic calculation unit 31, a first display control unit 41, a second display control unit 42, and a third display control unit 43. I have.

  The display screen 10 is a display screen provided in a single display device or a single application window displayed on the display screen. The display screen 10 includes a first area 11, a second area 12, and a third area. As shown in FIG. 2, the first area 11, the second area 12, and the third area 13 are arranged in the vertical direction in the display screen 10.

  The first signal receiving unit 21 receives a first signal corresponding to the administration state of at least one of a muscle relaxant and an antagonist for a subject. The administration state is information including the type of the administered drug, the amount of the administered drug, and the timing (time etc.) of administering the drug. The first signal is input to the first signal receiver 21 through, for example, an electronic anesthesia recording system.

  The kinetic calculator 31 acquires the pharmacokinetics of the drug administered to the subject by calculation based on the first signal received by the first signal receiver 21. Pharmacokinetics is information including the blood concentration and the effect site concentration of the administered drug. The relationship between the administration state of the drug and the pharmacokinetics is calculated using a known relational expression. That is, the acquired pharmacokinetics is not an actual measurement value of the drug concentration administered into the body of the subject but a value simulated by calculation.

  The first display control unit 41 displays the drug administration state trend 61 in the first region 11 of the display screen 10 based on the first signal received by the first signal receiving unit 21. In the first region 11 shown in FIG. 2, the horizontal axis represents time, and the vertical axis represents the dose of the drug. For example, the trend of the administration state of the muscle relaxant is displayed in the first region 11 in a bar graph form. That is, the height of each bar graph indicates the dose of the muscle relaxant, and the horizontal width of each bar graph indicates the duration of administration of the muscle relaxant.

  The second display control unit 42 displays the pharmacokinetic trend 62 obtained by the calculation by the kinetic calculation unit 31 in the second region 12 of the display screen 10. In the second region 12 shown in FIG. 2, the horizontal axis represents time, and the vertical axis represents drug concentration. For example, the second region 12 displays the result of simulating changes over time in the blood concentration 62a and the effect site concentration 62b of the muscle relaxant administered to the subject.

  The second signal receiving unit 22 receives a second signal corresponding to the response of the subject's muscle to the first electrical stimulation. The first electrical stimulation is given to the subject based on, for example, TOF (Train of Four) stimulation using a known muscle relaxation monitor device. In TOF stimulation, one set of four consecutive stimulations at 0.5 second intervals is used, and one set of stimulation is repeated at 15 second intervals. In this case, the muscle response to the first electrical stimulation (an example of the first response) is represented by the TOF ratio. The TOF ratio indicates the ratio of the response to the first stimulus and the response to the fourth stimulus in the one set. When the muscle relaxant is not acting, the TOF ratio is 100%. There is also an index% T1 indicating the muscle contraction rate with respect to the first stimulus. The second signal corresponding to the TOF ratio and% T1 is input to the second signal receiving unit 22 through the muscle relaxation monitor device.

  The third display control unit 43 displays the trend 63 of the TOF ratio and% T1 in the third region 13 of the display screen 10 based on the second signal received by the second signal receiving unit 22. In the third region 13 shown in FIG. 2, the horizontal axis indicates time, and the vertical axis indicates the TOF ratio and% T1. For example, the TOF ratio obtained for a predetermined stimulus is displayed in the third region 13 in a plot mode and% T1 is displayed in a bar graph. That is, the height of each plot and each bar graph indicates the size of the TOF ratio and% T1, respectively, and the position of each plot and each bar graph in the horizontal axis direction indicates the time when the TOF ratio and% T1 are obtained, respectively. Show.

  As shown in FIG. 2, the first display control unit 41, the second display control unit 42, and the third display control unit 43 include a drug administration state trend 61, a pharmacokinetic trend 62, and TOF ratio and% T1. The trends 63 are displayed on the display screen 10 so as to be arranged in the vertical direction in a time-synchronized state. That is, the data included in each of the drug administration state trend 61, the pharmacokinetic trend 62, and the TOF ratio and% T1 trend 63 located on the vertical line T0 in FIG. 2 is data acquired at the same time. Means that.

  According to such a configuration, since the trend 61 of the drug administration state, the trend 62 of the pharmacokinetics, and the trend 63 of the TOF ratio and% T1 are displayed together in the single display screen 10, anesthesiology Medical workers such as doctors can eliminate the complexity of the work of comparing these trend information provided through separate screens. Furthermore, since these trend information is aligned vertically in a time-synchronized manner, it is easy to intuitively understand the relationship between the trend information, and the appropriate dose and timing of the drug according to the depth of anesthesia. Judgment becomes easier. Therefore, the burden on medical personnel such as anesthesiologists can be reduced.

  As shown in FIG. 1, the display device 1 further includes a third signal receiving unit 23 and a fourth display control unit 44. The display screen 10 further includes a fourth region 14. As shown in FIG. 2, the fourth area 14 is arranged below the third area 13 in the display screen 10.

  The third signal receiving unit 23 receives a third signal for the reaction of the subject's muscle to the second electrical stimulation. The second electrical stimulus is a stronger stimulus than the first electrical stimulus. The second electrical stimulation is given to the subject based on, for example, a PTC (Post TetanicCount) stimulation using a known muscle relaxation monitor device. In PTC stimulation, first, 1 Hz stimulation is applied 15 times, and if it is confirmed that there is no response to the stimulation, tetanus stimulation is applied. Tetanus stimulation gives 50 Hz or 100 Hz stimulation for 5 seconds. 3 seconds later, 1 Hz stimulation is given 15 times, and the time when the next response to 4 continuous stimulations (TOF stimulation) appears is estimated from the number of appearing responses. The number of reactions that appear is called PTC. In addition, when TOF stimulation is performed and% T1 is less than 20% or% T4 (the fourth contraction rate of TOF stimulation) is 0%, it is referred to as TOF count indicating how many times there is a response to four stimulations. There are also indicators. The third signal corresponding to at least one of the PTC and the TOF count is input to the third signal receiving unit 23 through the muscle relaxation monitoring device.

  The fourth display control unit 44 displays the trend 64 of the PTC and TOF counts in the fourth region 14 of the display screen 10 based on the third signal received by the third signal receiving unit 23. In the fourth region 14 shown in FIG. 2, the horizontal axis represents time, and the vertical axis represents PTC and TOF count. For example, the TOF count obtained for a predetermined stimulus is displayed in the fourth region 14 in a bar graph form and the PTC in a plot form. That is, the height of each bar graph and each plot indicates the magnitude of the TOF count and PTC, respectively, and the position of each bar graph and each plot in the horizontal axis direction indicates the time when the TOF count and PTC were obtained. .

  As shown in FIG. 2, the fourth display control unit 44 sets the TOF count and the PTC trend 64 over time with respect to the drug administration state trend 61, the pharmacokinetic trend 62, and the TOF ratio and% T1 trend 63. Are displayed on the display screen 10 so as to be aligned vertically in a synchronized state. That is, the data included in each of the drug administration state trend 61, the pharmacokinetic trend 62, the TOF ratio and% T1 trend 63, and the TOF count and PTC trend 64 located on the vertical line T0 in FIG. It means that the data was acquired at the time.

  According to such a configuration, in addition to the drug administration state trend 61, the pharmacokinetic trend 62, and the TOF ratio and% T1 trend 63, the TOF count and the PTC trend 64 are aggregated in a single display screen 10. Thus, the medical staff such as anesthesiologists can eliminate the troublesome work of comparing these trend information provided through separate screens. In particular, the trend of TOF count and PTC, which are muscle relaxation information in a deep state of anesthesia, is displayed in a time synchronized state with other trend information. Judgment of administration timing is more reliable. Therefore, the burden on medical personnel such as anesthesiologists can be reduced.

  As shown in FIG. 1, the display device 1 further includes an instruction input unit 24. A user instruction is input to the instruction input unit 24. The instruction includes an instruction for selecting whether the fourth region 14 is to be displayed or not. The fourth display control unit 44 can switch between display and non-display of the fourth region 14 on the display screen 10 based on the instruction. FIG. 3 shows the display screen 10 in a state where the fourth area 14 is not displayed.

  According to such a configuration, the fourth region 14 can appear on the display screen 10 only when necessary. Under the situation where it is not necessary to display the TOF count and the PTC trend 64, the visible information can be minimized by switching the fourth area 14 to the non-display state as shown in FIG. As a result, medical personnel such as anesthesiologists can concentrate on necessary judgment work. Therefore, the burden on medical personnel such as anesthesiologists can be reduced.

  FIG. 4 shows another example of the trend 61 of the drug administration state displayed in the first region 11 of the display screen 10. In this example, the first display control unit 41 antagonizes the administration state of the muscle relaxant on the upper side (an example of the first side) of the time axis 11a in the first region 11 and the lower side (an example of the second side). The administration state of the drug is displayed. The bar graph 61a indicating administration of the muscle relaxant extends upward from the time axis 11a as the dosage increases, and the bar graph 61b indicating administration of the antagonist extends downward from the time axis 11a as the dosage increases. The color of the bar graph 61a is preferably different from the color of the bar graph 61b.

  According to such a configuration, administration states of different types of drugs can be intuitively grasped without causing confusion. Therefore, the burden on medical personnel such as anesthesiologists can be reduced.

  As shown in FIG. 1, the display device 1 further includes a dose calculation unit 51 and a dose output unit 52.

  Based on the pharmacokinetic trend 62 and the TOF ratio trend 63, the dose calculator 51 obtains a sustained dose of the muscle relaxant by calculation. Specifically, based on the value of the pharmacokinetics of the muscle relaxant acquired by the dynamic calculation unit 31 and the value of the TOF ratio indicated by the second signal received by the second signal receiving unit 22, the first time shown in FIG. The time T (recovery time after the first administration) from when the trend curve of the muscle relaxant blood concentration 62a associated with the muscle relaxant administration event A to the TOF ratio exceeds a predetermined threshold is acquired. Then, the dose calculation unit 51 acquires the dose (continuous dose) in the next muscle relaxant administration event B based on the recovery time T after the first administration. For subsequent muscle relaxant administration events C and D, the sustained dose is obtained in the same manner as necessary.

The following equation is known as a method for obtaining the continuous administration concentration (concentration at the time of stabilization) of the muscle relaxant from the recovery time T after the first administration. The sustained dose of the muscle relaxant is obtained using a known conversion formula based on the stable concentration obtained by the following formula.

Concentration at stable time (μg / ml) = 2.6-0.03 × T (min)

  When the TOF ratio continues to exceed the threshold value for a predetermined time, the dose calculation unit 51 determines the time when the threshold value is exceeded as data for obtaining the recovery time T after the first administration. According to such a configuration, it is possible to avoid a situation in which an erroneous recovery time T after the first administration is acquired due to the TOF ratio temporarily exceeding the threshold value due to noise or the like.

  The dose output unit 52 outputs information indicating the sustained dose acquired by the dose calculation unit 51. For example, the dose output unit 52 displays a number indicating the continuous dose at any location on the display screen 10.

  According to such a configuration, based on the first muscle relaxant administration event, information indicating the continuous dose of the muscle relaxant in the subsequent muscle relaxant administration event is automatically provided. A medical worker such as an anesthesiologist can determine the continuous dose based on the information without depending on judgment based on experience and intuition. Therefore, the burden on medical personnel such as anesthesiologists can be reduced.

  The above embodiment is for facilitating understanding of the present invention, and does not limit the present invention. The present invention can be modified and improved without departing from the spirit of the present invention, and it is obvious that the present invention includes equivalents thereof.

  The first area 11, the second area 12, the third area 13, and the fourth area 14 on the display screen 10 do not necessarily need to be arranged in the vertical direction. As long as various trends are displayed in a time-synchronized state, the direction of the time axis is the vertical direction, and the first area 11, the second area 12, the third area 13, and the fourth area 14 are in the horizontal direction. It is good also as a structure displayed so that it may rank.

  The trends displayed in the third area 13 and the fourth area 14 do not need to be TOF ratio and% T1, and TOF count and PTC trends, respectively. The third region 13 may be configured to display only one of the TOF ratio and% T1. The fourth area 14 may be configured to display only one of the TOF count and the PTC. About the 3rd field 13, the trend of arbitrary information can be displayed as long as it shows reaction of a subject's muscle to the 1st electric stimulus. About the 4th field 14, the trend of arbitrary information can be displayed, as long as it shows reaction of a subject's muscle to the 2nd electric stimulus stronger than the 1st electric stimulus.

  The information indicating the continuous dose output by the dose output unit 52 does not necessarily need to be displayed on the display screen 10 in the form of numbers. As long as a medical worker such as an anesthesiologist can recognize, the data may be output in various symbols, colors, sounds, and the like. Further, as indicated by a broken line in FIG. 1, the output destination of the information is not limited to the display screen 10. It may be output as data in a format that can be stored in a storage device (not shown). Further, the data may be output as data in a format that can be transmitted to another device through a communication network (not shown).

  As shown in FIG. 1, the display device 1 may be configured by a display screen 10 and a computer connected to the display screen 10. In this case, the present invention can be realized as a program for controlling the display device 1. The program includes the first signal receiving unit 21, the second signal receiving unit 22, the third signal receiving unit 23, the instruction input unit 24, the dynamic calculation unit 31, the first display control unit 41, and the second described above. It operates as at least one of the display control unit 42, the third display control unit 43, the fourth display control unit 44, the dose calculation unit 51, and the dose output unit 52.

  1: display device, 10: display screen, 11: first region, 11a: time axis, 12: second region, 13: third region, 14: fourth region, 21: first signal receiver, 22: first 2 signal receiving unit, 23: third signal receiving unit, 24: instruction input unit, 31: dynamic calculation unit, 41: first display control unit, 42: second display control unit, 43: third display control unit, 44 : Fourth display control unit, 51: dose calculation unit, 52: dose output unit, 61: trend of drug administration state, 61a: trend of administration state of muscle relaxant, 61b: trend of administration state of antagonist, 62: Trend of pharmacokinetics, 63: Trend of TOF ratio and% T1, 64: Trend of TOF count and PTC

Claims (7)

A device for displaying muscle relaxation information,
A display screen;
A first signal receiving unit for receiving a first signal corresponding to an administration state of at least one of a muscle relaxant and an antagonist for a subject;
A second signal receiving unit that receives a second signal corresponding to a first response of the subject's muscle to a first electrical stimulus;
Based on the first signal, a kinetic calculator that acquires the pharmacokinetics of the drug by calculation;
A first display control unit configured to display a trend of the administration state in a first region of the display screen based on the first signal;
A second display control unit for displaying the pharmacokinetic trend in a second region of the display screen;
A third display control unit configured to display a trend of the first reaction in a third region of the display screen based on the second signal;
The first display control unit, the second display control unit, and the third display control unit are time-synchronized with the administration state trend, the pharmacokinetic trend, and the first reaction trend. A display device that is displayed on the display screen in a state. A second signal receiving unit receives a third signal corresponding to a second response of the subject's muscle to a second electrical stimulus stronger than the first electrical stimulus;
A fourth display control unit configured to display a trend of the second reaction in a fourth region of the display screen based on the third signal;
The fourth display control unit is configured so that the second reaction trend is temporally synchronized with the administration state trend, the pharmacokinetic trend, and the first reaction trend. The display device according to claim 1, which is displayed on the display. An instruction input unit for inputting user instructions;
The display device according to claim 2, wherein the fourth display control unit can switch between display and non-display of the fourth region based on the instruction.   The first display control unit displays the administration state of the muscle relaxant on the first side of the time axis in the first region and displays the administration state of the antagonist on the second side of the time axis. The display device according to any one of claims 1 to 3. Based on the trend of the pharmacokinetics and the trend of the first reaction, a dose calculation unit that obtains a sustained dose of the muscle relaxant by calculation,
The display apparatus as described in any one of Claim 1 to 4 provided with the dosage output part which outputs the information which shows the said continuous dosage. A method for displaying muscle relaxation information,
A trend of administration state of at least one of a muscle relaxant and an antagonist is displayed in the first area of the display screen,
The pharmacokinetic trend of the drug obtained by calculation is displayed in the second area of the display screen,
The trend of the first response of the subject's muscle to the first electrical stimulation is displayed in the third area of the display screen,
The display method, wherein the administration state trend, the pharmacokinetic trend, and the first reaction trend are displayed on the display screen in a time-synchronized state. A program for controlling a display device for muscle relaxation information,
The display device includes a display screen and a computer connected to the display screen,
The program causes the computer to
A first signal receiving unit for receiving a first signal corresponding to the administration state of at least one of the muscle relaxant and the antagonist;
A second signal receiving unit for receiving a second signal corresponding to the first reaction of the muscle of the subject to the first electrical stimulation;
Based on the first signal, a kinetic calculator that acquires the pharmacokinetics of the drug by calculation,
A first display control unit configured to display a trend of the administration state in a first region of the display screen based on the first signal;
A second display control section for displaying the pharmacokinetic trend in the second area of the display screen; and a third display for displaying the trend of the first reaction in the third area of the display screen based on the second signal. Operate as a display controller,
The first display control unit and the second display so that the administration state trend, the pharmacokinetic trend, and the first reaction trend are displayed on the display screen in a time-synchronized state. A program for operating a control unit and the third display control unit.

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