JP2009291373A - Capsule medical apparatus - Google Patents

Capsule medical apparatus Download PDF

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JP2009291373A
JP2009291373A JP2008147321A JP2008147321A JP2009291373A JP 2009291373 A JP2009291373 A JP 2009291373A JP 2008147321 A JP2008147321 A JP 2008147321A JP 2008147321 A JP2008147321 A JP 2008147321A JP 2009291373 A JP2009291373 A JP 2009291373A
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injection needle
body part
capsule
medical device
needle
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JP5203050B2 (en
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Hironobu Takizawa
寛伸 瀧澤
Hironao Kono
宏尚 河野
Masaki Takahashi
正樹 高橋
Shinsuke Tanaka
慎介 田中
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Olympus Medical Systems Corp
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Olympus Medical Systems Corp
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Priority to JP2008147321A priority Critical patent/JP5203050B2/en
Application filed by Olympus Medical Systems Corp filed Critical Olympus Medical Systems Corp
Priority to AT09006092T priority patent/ATE505128T1/en
Priority to US12/435,121 priority patent/US8517917B2/en
Priority to EP10006693.5A priority patent/EP2238885B1/en
Priority to EP09006092A priority patent/EP2130481B1/en
Priority to DE602009001050T priority patent/DE602009001050D1/en
Priority to CN200910202954XA priority patent/CN101596093B/en
Priority to CN201110187724.8A priority patent/CN102284127B/en
Publication of JP2009291373A publication Critical patent/JP2009291373A/en
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A61M31/002—Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/00064—Constructional details of the endoscope body
    • A61B1/00071—Insertion part of the endoscope body
    • A61B1/0008—Insertion part of the endoscope body characterised by distal tip features
    • A61B1/00087—Tools
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/04—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances
    • A61B1/041—Capsule endoscopes for imaging
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B34/00—Computer-aided surgery; Manipulators or robots specially adapted for use in surgery
    • A61B34/70—Manipulators specially adapted for use in surgery
    • A61B34/73—Manipulators for magnetic surgery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
    • A61M5/14248—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body of the skin patch type
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/44—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for cooling or heating the devices or media
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
    • A61M5/14248—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body of the skin patch type
    • A61M2005/14252—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body of the skin patch type with needle insertion means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/02—General characteristics of the apparatus characterised by a particular materials
    • A61M2205/0266—Shape memory materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
    • A61M5/148—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons flexible, e.g. independent bags
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/329—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles characterised by features of the needle shaft

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
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  • Heart & Thoracic Surgery (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Radiology & Medical Imaging (AREA)
  • Biophysics (AREA)
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  • Dermatology (AREA)
  • Robotics (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Endoscopes (AREA)

Abstract

<P>PROBLEM TO BE SOLVED: To prevent a drug solution from leaking from the internal region of a subject after pulling out an injection needle from the internal region after the injection of the drug solution. <P>SOLUTION: A capsule medical apparatus 1 includes: a thermoplastic injection needle 3; a driving unit 6 that protrudes and stores the injection needle 3 from and inside a capsule case body 2; a heater 4 that heats the injection needle 3; a discharge balloon 8 that injects a drug solution 7; a driving valve 9 that switches the state between the injection needle 3 and the discharge balloon 8 from a communicated state to a blocked state and vice versa; and a control unit 13. The driving unit 6 drives the injection needle 3 so that the injection needle punctures the internal region based on the control of a control unit 13. The control unit 13 controls the driving valve 9 so that the driving valve opens, and starts the injection of the drug solution 7 using the discharge balloon 8. After the injection is completed, the heater 4 heats the injection needle 3 in a puncturing state so that the injection needle 3 contracts, using power supplied from the control unit 13. A puncture hole of the internal region is sealed accompanying contraction of the injection needle 3. <P>COPYRIGHT: (C)2010,JPO&INPIT

Description

本発明は、被検体内部に導入され、被検体内部の所望部位に薬液等の液体を注射する局注機能を備えたカプセル型医療装置に関するものである。   The present invention relates to a capsule medical device having a local injection function that is introduced into a subject and injects a liquid such as a drug solution into a desired site inside the subject.

従来から、内視鏡の分野において、被検体の臓器内部に導入されて臓器内部の画像（以下、体内画像という場合がある）を撮像するカプセル型医療装置が登場している。カプセル型医療装置は、カプセル型筐体の内部に撮像機能と無線通信機能とを備え、患者等の被検体に経口摂取された後、蠕動運動等によって消化管内を移動しつつ被検体の体内画像を順次撮像する。カプセル型医療装置は、被検体の体内画像を撮像する都度、被検体外部の受信装置に体内画像を順次無線送信する。なお、被検体内部に導入されたカプセル型内視鏡は、最終的に被検体外部に排出される。   2. Description of the Related Art Conventionally, in the field of endoscopes, a capsule medical device that has been introduced into an organ of a subject and images an image inside the organ (hereinafter also referred to as an in-vivo image) has appeared. The capsule medical device has an imaging function and a wireless communication function inside the capsule housing, and after being orally ingested by a subject such as a patient, the in-vivo image of the subject while moving in the digestive tract by peristalsis or the like Are sequentially imaged. Each time a capsule medical device captures an in-vivo image of a subject, the capsule medical device sequentially transmits the in-vivo image sequentially to a receiving device outside the subject. Note that the capsule endoscope introduced into the subject is finally discharged out of the subject.

また、このようなカプセル型医療装置には、被検体の体内部位に薬液を注射する局注機能を備えたものがある（例えば、特許文献１，２参照）。この特許文献１，２に開示されたカプセル型医療装置は、被検体の体内部位に注射針を穿刺し、この穿刺した注射針を介して薬液を体内部位に注入する。その後、カプセル型医療装置は、この体内部位に穿刺していた注射針を抜き取り、カプセル型筺体の内部に注射針を収納する。   Some of such capsule medical devices have a local injection function for injecting a drug solution into a body part of a subject (see, for example, Patent Documents 1 and 2). In the capsule medical devices disclosed in Patent Documents 1 and 2, an injection needle is punctured into a body part of a subject, and a medical solution is injected into the body part through the punctured injection needle. Thereafter, the capsule medical device removes the injection needle that has been punctured into the body part, and stores the injection needle inside the capsule housing.

なお、組織に治療薬を注射する方法には、注射装置によって組織に薬液を注射後に注射針を組織から抜き取り、その後、この組織の注射部位を高周波焼灼またはレーザー加熱によって焼灼、凝固し、これによって、この注射部位の針跡をシールするものがある（例えば、特許文献３参照）。   In the method of injecting a therapeutic agent into the tissue, the injection needle is withdrawn from the tissue after injecting the drug solution into the tissue with an injection device, and then the injection site of this tissue is cauterized and coagulated by high-frequency cauterization or laser heating. There is one that seals the needle mark at the injection site (see, for example, Patent Document 3).

特開２００６−４３１１５号公報JP 2006-43115 A 特開２００４−４１７０９号公報JP 2004-41709 A 特表２００３−５３０８９７号公報Japanese translation of PCT publication No. 2003-530897

しかしながら、上述した従来のカプセル型医療装置では、体内部位に穿刺した注射針を薬液注射後に抜き取った際、この体内部位の穿刺跡（針跡）から薬液が漏れ出る可能性がある。このように薬液注射後の体内部位から漏れ出た薬液は、目的外の体内部位にまで広がり、この目的外の体内部位に対して意図せずに作用してしまう。特に、薬液が有色の液体である場合、薬液注射後の体内部位から漏れ出た有色の薬液は、目的外の体内部位に作用するのみならず、カプセル型医療装置の外壁面に付着してカプセル型医療装置の視界（撮像視野）を妨げてしまう可能性がある。   However, in the above-described conventional capsule medical device, when the injection needle punctured into the body part is extracted after the liquid medicine injection, the liquid medicine may leak from the puncture trace (needle trace) of the body part. In this way, the drug solution leaking from the body part after injection of the drug solution spreads to an unintended body part and acts unintentionally on the body part outside the purpose. In particular, when the drug solution is a colored liquid, the colored drug solution leaking from the body part after injection of the drug solution not only acts on the unintended body part, but also adheres to the outer wall surface of the capsule medical device and becomes a capsule. May obstruct the field of view (imaging field of view) of the medical device.

本発明は、上記の事情に鑑みてなされたものであって、薬液注射後の体内部位から注射針を抜き取った後に、この体内部位から薬液が漏れ出ることを防止できるカプセル型医療装置を提供することを目的とする。   The present invention has been made in view of the above circumstances, and provides a capsule medical device that can prevent a medical solution from leaking out from a body part after the injection needle has been extracted from the body part after injection of the medical solution. For the purpose.

上述した課題を解決し、目的を達成するために、本発明にかかるカプセル型医療装置は、被検体の体内部位に注射針を穿刺し、この穿刺した前記注射針を前記体内部位から抜き取る針駆動手段と、前記体内部位に穿刺した前記注射針を介して前記体内部位の内部に液体を注入する液体注入手段と、前記液体注入手段が前記体内部位の内部に前記液体を注入してから前記針駆動手段が前記体内部位から前記注射針を抜き取るまでの期間に、前記注射針による前記体内部位の穿刺穴を閉塞状態にする閉塞手段と、を備えたことを特徴とする。   In order to solve the above-described problems and achieve the object, a capsule medical device according to the present invention punctures an injection needle into a body part of a subject and removes the punctured injection needle from the body part. Means, liquid injecting means for injecting liquid into the internal body part through the injection needle punctured into the internal body part, and the needle after the liquid injecting means injects the liquid into the internal body part And occlusion means for closing the puncture hole of the in-vivo site by the injection needle until the drive means extracts the injection needle from the in-vivo site.

また、本発明にかかるカプセル型医療装置は、上記の発明において、前記閉塞手段は、前記注射針の外径を変化させる針径変化手段であることを特徴とする。   The capsule medical device according to the present invention is characterized in that, in the above invention, the closing means is a needle diameter changing means for changing an outer diameter of the injection needle.

また、本発明にかかるカプセル型医療装置は、上記の発明において、前記針径変化手段は、前記注射針を加熱処理によって縮小変形させて前記穿刺穴を閉塞状態にする加熱手段であり、前記注射針は、熱可塑性樹脂によって形成され、前記体内部位に穿刺した状態で前記加熱手段によって加熱処理された場合、前記体内部位の収縮力によって縮小変形することを特徴とする。   In the capsule medical device according to the present invention as set forth in the invention described above, the needle diameter changing means is a heating means that shrinks and deforms the injection needle by a heat treatment to close the puncture hole. The needle is formed of a thermoplastic resin, and when the needle is heat-treated by the heating means in a state where the needle is punctured, the needle is reduced and deformed by a contraction force of the body part.

また、本発明にかかるカプセル型医療装置は、上記の発明において、前記閉塞手段は、前記注射針に摺動可能に外嵌し、前記体内部位に穿刺する前記注射針とともに前記穿刺穴に入る軟質管と、前記体内部位に向けて前記注射針とともに前記軟質管を突出させ、前記針駆動手段が前記体内部位から前記注射針を抜き取るまでの期間、前記穿刺穴に前記軟質管を留め、前記注射針の抜き取り後に前記体内部位から前記軟質管を抜き取って、前記カプセル型筐体の内部に前記軟質管を収納する管駆動手段と、を備え、前記軟質管は、前記注射針に外嵌した状態で管形状を維持し、前記針駆動手段によって前記体内部位から前記注射針が抜き取られるとともに前記体内部位の収縮力によって縮小変形して、前記穿刺穴を閉塞状態にすることを特徴とする。   In the capsule medical device according to the present invention as set forth in the invention described above, the occluding means is a soft fitting that slidably fits on the injection needle and enters the puncture hole together with the injection needle that punctures the body part. The soft tube is projected together with the injection needle toward the body part with the tube, and the soft tube is retained in the puncture hole for a period until the needle driving means pulls out the injection needle from the body part, and the injection A tube driving means for extracting the soft tube from the body part after extraction of the needle and storing the soft tube inside the capsule-type housing, and the soft tube is externally fitted to the injection needle Maintaining the tube shape, the needle drive means pulls out the injection needle from the body part, and contracts and deforms by the contraction force of the body part, thereby closing the puncture hole That.

また、本発明にかかるカプセル型医療装置は、上記の発明において、前記閉塞手段は、前記体内部位の収縮速度に比して低い速度で前記体内部位から前記注射針を抜き取るように前記針駆動手段を制御する制御手段を備えたことを特徴とする。   In the capsule medical device according to the present invention as set forth in the invention described above, the occlusion means is configured to remove the injection needle from the body part at a speed lower than a contraction speed of the body part. It is characterized by comprising control means for controlling.

また、本発明にかかるカプセル型医療装置は、上記の発明において、前記閉塞手段は、前記注射針の長手軸回りに前記注射針を回転する回転駆動手段をさらに備え、前記制御手段は、前記体内部位に前記注射針を穿刺する場合、前記注射針の先端開口部が前記体内部位側に向くように前記回転駆動手段を制御し、前記体内部位から前記注射針を抜き取る場合、前記先端開口部の方向が反転する態様に前記注射針を回転するように前記回転駆動手段を制御することを特徴とする。   In the capsule medical device according to the present invention as set forth in the invention described above, the closing means further includes a rotation driving means for rotating the injection needle around a longitudinal axis of the injection needle, and the control means When the injection needle is punctured into a site, the rotation driving means is controlled so that the distal end opening of the injection needle faces the in-vivo site, and when the injection needle is withdrawn from the in-vivo site, The rotation driving means is controlled to rotate the injection needle in such a manner that the direction is reversed.

また、本発明にかかるカプセル型医療装置は、上記の発明において、前記閉塞手段は、前記注射針の周囲の生体組織を焼灼して前記穿刺穴を閉塞状態にする焼灼手段であることを特徴とする。   The capsule medical device according to the present invention is characterized in that, in the above invention, the closing means is ablation means for cauterizing a living tissue around the injection needle to close the puncture hole. To do.

また、本発明にかかるカプセル型医療装置は、上記の発明において、前記焼灼手段は、前記カプセル型筐体の外壁部であって前記注射針の突没口の近傍に配置されることを特徴とする。   Also, the capsule medical device according to the present invention is characterized in that, in the above invention, the cauterizing means is disposed on an outer wall portion of the capsule casing and in the vicinity of a projecting / retracting opening of the injection needle. To do.

また、本発明にかかるカプセル型医療装置は、上記の発明において、前記焼灼手段は、前記注射針であることを特徴とする。   In the capsule medical device according to the present invention as set forth in the invention described above, the ablation means is the injection needle.

また、本発明にかかるカプセル型医療装置は、上記の発明において、前記カプセル型筐体から前記焼灼手段を突没させて、前記注射針の近傍であって前記体内部位の表面に前記焼灼手段を接触させ、前記穿刺穴を閉塞状態にした後、前記カプセル型筐体の内部に前記焼灼手段を収納する焼灼部駆動手段を備え、前記焼灼手段は、前記注射針を内部に挿通可能な管形状に形成され、前記注射針は、前記焼灼手段の内部を通って突没することを特徴とする。   The capsule medical device according to the present invention is the capsule medical device according to the above-described invention, wherein the cauterizing means is protruded and subtracted from the capsule-type housing, and the cauterizing means is provided on the surface of the body part in the vicinity of the injection needle. After making the contact and closing the puncture hole, the capsule-type housing includes a cautery unit driving means for accommodating the cauterization means, and the cauterization means has a tube shape through which the injection needle can be inserted. The injection needle protrudes and sinks through the inside of the cauterizing means.

また、本発明にかかるカプセル型医療装置は、上記の発明において、前記閉塞手段は、前記注射針を穿刺する前記体内部位の表面を変形させて前記穿刺穴を閉塞状態にすることを特徴とする。   In the capsule medical device according to the present invention as set forth in the invention described above, the occluding means deforms the surface of the internal body part through which the injection needle is punctured to close the puncture hole. .

また、本発明にかかるカプセル型医療装置は、上記の発明において、前記閉塞手段は、前記体内部位に穿刺した状態の前記注射針の近傍の生体組織を伸展して前記穿刺穴を閉塞状態にする組織伸展機構であることを特徴とする。   In the capsule medical device according to the present invention as set forth in the invention described above, the blocking means extends the living tissue in the vicinity of the injection needle in a state of puncturing the body part to close the puncture hole. It is a tissue extension mechanism.

また、本発明にかかるカプセル型医療装置は、上記の発明において、前記針駆動手段は、前記体内部位の表面と前記注射針とのなす角度を９０度より小さくした態様で前記体内部位に前記注射針を穿刺することを特徴とする。   In the capsule medical device according to the present invention as set forth in the invention described above, the needle driving means may inject the injection into the internal body part in an aspect in which an angle formed by the surface of the internal body part and the injection needle is smaller than 90 degrees. The needle is punctured.

また、本発明にかかるカプセル型医療装置は、上記の発明において、前記針駆動手段は、当該カプセル型医療装置のカプセル型筐体から前記注射針を突没させて、前記被検体の体内部位に前記注射針を穿刺し、この穿刺した前記注射針を前記体内部位から抜き取って、前記カプセル型筐体の内部に前記注射針を収納することを特徴とする。   In the capsule medical device according to the present invention as set forth in the invention described above, the needle driving means causes the injection needle to protrude and retract from a capsule housing of the capsule medical device to the body part of the subject. The injection needle is punctured, the punctured injection needle is removed from the body part, and the injection needle is housed inside the capsule-type housing.

また、本発明にかかるカプセル型医療装置は、上記の発明において、当該カプセル型医療装置のカプセル型筐体から前記注射針を突没させる突没駆動手段を備え、前記針駆動手段は、外部磁界に追従して回転駆動して、前記突没駆動手段によって突出した前記注射針を前記被検体の体内部位に穿刺し、この穿刺した前記注射針を前記体内部位から抜き取る磁石であることを特徴とする。   The capsule medical device according to the present invention further comprises a protrusion drive unit that protrudes and retracts the injection needle from the capsule housing of the capsule medical device according to the above-described invention, and the needle drive unit includes an external magnetic field. The injection needle is a magnet that is driven to rotate following the protrusion and punctures the injection needle projecting by the protrusion / contraction drive means into the body part of the subject and removes the puncture needle from the body part. To do.

本発明にかかるカプセル型医療装置は、針駆動手段が、カプセル型筐体から注射針を突没させて、被検体の体内部位に前記注射針を穿刺し、この穿刺した前記注射針を前記体内部位から抜き取って、前記カプセル型筐体の内部に前記注射針を収納し、液体注入手段が、前記体内部位に穿刺した前記注射針を介して前記体内部位の内部に液体を注入し、閉塞手段が、前記液体注入手段が前記体内部位の内部に前記液体を注入してから前記針駆動手段が前記体内部位から前記注射針を抜き取るまでの期間に、前記注射針による前記体内部位の穿刺穴を閉塞状態にするので、この体内部位の穿刺穴から薬液等の注入液体を漏出させることなく、この穿刺穴を閉塞状態に変化することができ、この結果、薬液注射後の体内部位から注射針を抜き取った後に、この体内部位から薬液が漏れ出ることを防止できるという効果を奏する。   In the capsule medical device according to the present invention, the needle driving means causes the injection needle to protrude and retract from the capsule-type housing, punctures the injection needle into a body part of a subject, and inserts the punctured injection needle into the body. The injection needle is extracted from the part, and the injection needle is accommodated in the capsule-type housing, and the liquid injection means injects the liquid into the internal part through the injection needle punctured into the internal part, and the blocking means. However, during the period from when the liquid injection means injects the liquid into the body part until the needle driving means pulls out the injection needle from the body part, the puncture hole of the body part by the injection needle is formed. Since it is in an occluded state, the puncture hole can be changed to an occluded state without leaking infusion liquid such as a medicinal solution from the puncture hole in the in vivo part. Extracted In an effect that it is possible to prevent the drug solution from leaking from the in-vivo region.

以下、図面を参照して、本発明にかかるカプセル型医療装置の好適な実施の形態を詳細に説明する。なお、以下では、被検体内部の患部等の所望の体内部位に薬液を注入するカプセル型医療装置を例示するが、この実施の形態によって本発明が限定されるものではない。   DESCRIPTION OF EMBODIMENTS Hereinafter, preferred embodiments of a capsule medical device according to the present invention will be described in detail with reference to the drawings. In the following, a capsule medical device that injects a drug solution into a desired internal site such as an affected part inside a subject is exemplified, but the present invention is not limited to this embodiment.

（実施の形態１）
図１は、本発明の実施の形態１にかかるカプセル型医療装置の一構成例を示す模式図である。図１に示すように、この実施の形態１にかかるカプセル型医療装置１は、筒状筐体２ａとドーム形状筐体２ｂとによって形成されるカプセル型筐体２と、被検体の体内部位に穿刺する注射針３と、この注射針３を加熱処理によって縮小変形させる加熱部４と、注射針３を支持する支持部５と、カプセル型筐体２から注射針３を突没させる駆動部６とを備える。また、カプセル型医療装置１は、注射針３を介して体内部位に薬液７を注入する吐出バルーン８と、この吐出バルーン８と注射針３との連通状態と遮断状態とを切り替える駆動弁９と、連通管１０ａと、チューブ１０ｂとを備える。さらに、カプセル型医療装置１は、被検体の体内画像を撮像する撮像部１１と、被検体外部の通信装置（図示せず）と無線通信を行う通信部１２と、かかるカプセル型医療装置１の各構成部を制御する制御部１３と、電池等によって実現される電源部１４とを備える。 (Embodiment 1)
FIG. 1 is a schematic diagram illustrating a configuration example of a capsule medical device according to the first embodiment of the present invention. As shown in FIG. 1, the capsule medical device 1 according to the first embodiment includes a capsule housing 2 formed by a cylindrical housing 2a and a dome-shaped housing 2b, and a body part of a subject. The injection needle 3 for puncturing, the heating unit 4 for reducing and deforming the injection needle 3 by heat treatment, the support unit 5 for supporting the injection needle 3, and the drive unit 6 for projecting and retracting the injection needle 3 from the capsule housing 2 With. In addition, the capsule medical device 1 includes a discharge balloon 8 that injects a drug solution 7 into a body part via the injection needle 3, and a drive valve 9 that switches between a communication state and a cutoff state of the discharge balloon 8 and the injection needle 3. The communication pipe 10a and the tube 10b are provided. Furthermore, the capsule medical device 1 includes an imaging unit 11 that captures an in-vivo image of a subject, a communication unit 12 that performs wireless communication with a communication device (not shown) outside the subject, and the capsule medical device 1. The control part 13 which controls each structure part and the power supply part 14 implement | achieved by the battery etc. are provided.

カプセル型筐体２は、患者等の被検体の内部に導入可能な大きさに形成されたカプセル型の筐体であり、一端がドーム形状をなす筒状筐体２ａの他端（開口端）をドーム形状筐体２ｂによって塞いで形成される。ドーム形状筐体２ｂは、所定の波長帯域の光（例えば可視光）に対して透明なドーム形状の光学部材である。一方、筒状筐体２ａは可視光に対して略不透明な筐体である。この筒状筐体２ａには、注射針３の突没口である開口部２ｃが形成される。かかる筒状筐体２ａとドーム形状筐体２ｂとによって形成されるカプセル型筐体２の内部には、カプセル型医療装置１の各構成部（注射針３、加熱部４、駆動部６、吐出バルーン８、駆動弁９、連通管１０ａ、チューブ１０ｂ、撮像部１１、通信部１２、制御部１３および電源部１４等）が収容される。この場合、カプセル型筐体２は、所定の液密構造（図示せず）によって、駆動部６、駆動弁９、撮像部１１、通信部１２、制御部１３および電源部１４等の電子部品の液密状態を確保する。   The capsule-type housing 2 is a capsule-type housing formed in a size that can be introduced into a subject such as a patient, and the other end (opening end) of the cylindrical housing 2a having one end having a dome shape. Is closed by a dome-shaped housing 2b. The dome-shaped housing 2b is a dome-shaped optical member that is transparent to light in a predetermined wavelength band (for example, visible light). On the other hand, the cylindrical housing 2a is a housing that is substantially opaque to visible light. The cylindrical housing 2a is formed with an opening 2c that is a projecting / recessing opening of the injection needle 3. Inside the capsule-type casing 2 formed by the cylindrical casing 2a and the dome-shaped casing 2b, each component of the capsule-type medical device 1 (the injection needle 3, the heating section 4, the driving section 6, discharge) A balloon 8, a drive valve 9, a communication tube 10a, a tube 10b, an imaging unit 11, a communication unit 12, a control unit 13, a power supply unit 14, and the like) are accommodated. In this case, the capsule-type housing 2 has a predetermined liquid-tight structure (not shown), and electronic components such as the drive unit 6, the drive valve 9, the imaging unit 11, the communication unit 12, the control unit 13, and the power supply unit 14 are arranged. Ensure liquid tightness.

注射針３は、一端（先端）が尖形に形成された中空針であり、熱可塑性樹脂によって形成される。この注射針３の他端（後端）にはチューブ１０ｂが取り付けられ、この注射針３の後端部近傍には、支持部５が固定される。支持部５は、カプセル型筐体２の開口部２ｃを通して注射針３が突没可能な態様で注射針３を支持する。かかる支持部５は、駆動部６と接続される。一方、この注射針３の外壁部には加熱部４が取り付けられる。かかる注射針３は、所定の温度未満（例えば体温以下の温度）の状態である場合、かかる中空針としての外形を維持し、加熱部４によって所定の温度以上に加熱された場合、軟化して流動性をもつようになり、体内部位の収縮力によって容易に変形可能になる。   The injection needle 3 is a hollow needle having one end (tip) formed into a pointed shape, and is formed of a thermoplastic resin. A tube 10 b is attached to the other end (rear end) of the injection needle 3, and a support portion 5 is fixed near the rear end portion of the injection needle 3. The support portion 5 supports the injection needle 3 in such a manner that the injection needle 3 can project and retract through the opening 2 c of the capsule housing 2. The support unit 5 is connected to the drive unit 6. On the other hand, a heating unit 4 is attached to the outer wall of the injection needle 3. When the injection needle 3 is in a state of less than a predetermined temperature (for example, a temperature equal to or lower than the body temperature), the outer shape as the hollow needle is maintained, and when heated by the heating unit 4 to a predetermined temperature or more, the injection needle 3 is softened. It becomes fluid and can be easily deformed by the contraction force of the body part.

加熱部４は、熱可塑性樹脂からなる注射針３を加熱処理によって縮小変形させて注射針３による体内部位の穿刺穴を閉塞状態にする閉塞手段として機能する。具体的には、加熱部４は、薄膜状の電熱ヒータであり、注射針３の外壁部に巻き付けられる態様で固定される。かかる加熱部４は、制御部１３によって供給された電力をもとに注射針３を加熱処理し、これによって注射針３を軟化させて縮小変形可能な状態にする。かかる加熱部４によって加熱された注射針３は、穿刺した体内部位の収縮力によって容易に縮小変形して穿刺穴を閉塞状態にする。   The heating unit 4 functions as an occlusion means that causes the injection needle 3 made of a thermoplastic resin to be contracted and deformed by heat treatment to close the puncture hole in the body part by the injection needle 3. Specifically, the heating unit 4 is a thin-film electric heater, and is fixed in a manner of being wound around the outer wall portion of the injection needle 3. The heating unit 4 heats the injection needle 3 based on the electric power supplied by the control unit 13, thereby softening the injection needle 3 so that it can be deformed in a reduced size. The injection needle 3 heated by the heating unit 4 is easily reduced and deformed by the contraction force of the punctured body part to close the puncture hole.

ここで、かかる閉塞状態は、注射針３の穿刺によって体内部位に形成された穿刺穴（穿刺跡）の開口径が縮小（最小化）して、この体内部位の注入液体（具体的には注射針３を介して体内部位の内部に注入された薬液等の液体）が穿刺穴から漏れ出ない状態であり、この穿刺穴が完全に塞がっていなくてもよい。また、上述した注射針３の縮小変形は、かかる穿刺穴の開口径を最小化する方向に進行する変形であり、例えば、注射針３の開口径を縮小する縮径変形、注射針３の開口を潰してフラットな形状にする圧潰変形等を含む。   Here, such an occluded state means that the diameter of the puncture hole (puncture mark) formed in the body part by the puncture of the injection needle 3 is reduced (minimized), and the infusion liquid (specifically, injection) Liquid such as a chemical solution injected into the body part via the needle 3 does not leak from the puncture hole, and the puncture hole may not be completely closed. Further, the above-described reduction deformation of the injection needle 3 is a deformation that proceeds in a direction that minimizes the opening diameter of the puncture hole. For example, the diameter reduction deformation that reduces the opening diameter of the injection needle 3 and the opening of the injection needle 3 are performed. Including crushing deformation to flatten the shape.

駆動部６は、カプセル型筐体２から注射針３を突没させて、被検体の体内部位に注射針３を穿刺し、この穿刺した注射針３を体内部位から抜き取ってカプセル型筐体２の内部に収納する針駆動手段として機能する。具体的には、駆動部６は、リニアアクチュエータ等を用いて実現され、注射針３の支持部５と接続される。駆動部６は、支持部５を介して注射針３を所定の方向（図１に示す太線矢印方向）に往復動作させる。かかる駆動部６は、開口部２ｃからカプセル型筐体２の外部に注射針３を突き出して被検体の体内部位に注射針３を穿刺し、その後、制御部１３の制御に基づく動作タイミングに体内部位から注射針３を抜き取り、カプセル型筐体２内部に注射針３を収納する。   The drive unit 6 protrudes and retracts the injection needle 3 from the capsule-type housing 2 to puncture the injection needle 3 into the body part of the subject, and removes the punctured injection needle 3 from the body part to obtain the capsule-type housing 2. It functions as a needle drive means that is housed inside the. Specifically, the drive unit 6 is realized using a linear actuator or the like, and is connected to the support unit 5 of the injection needle 3. The drive unit 6 causes the injection needle 3 to reciprocate in a predetermined direction (the direction of the thick arrow shown in FIG. 1) via the support unit 5. The drive unit 6 projects the injection needle 3 from the opening 2c to the outside of the capsule housing 2 and punctures the injection needle 3 into the body part of the subject, and then at the operation timing based on the control of the control unit 13 The injection needle 3 is extracted from the site, and the injection needle 3 is stored inside the capsule-type housing 2.

吐出バルーン８は、被検体の体内部位に穿刺した注射針３を介して、この体内部位の内部に液体を注入する液体注入手段として機能する。具体的には、吐出バルーン８は、伸縮自在な弾性膜によって実現され、連通管１０ａに取り付けられる。吐出バルーン８は、膨脹した状態で薬液７を内包し、この薬液７を貯蔵する。かかる吐出バルーン８の内部は、連通管１０ａと連通し、後述する駆動弁９が開状態である場合に連通管１０ａおよびチューブ１０ｂ等を介して注射針３と連通する。吐出バルーン８は、注射針３と連通状態である場合、自身の収縮力によって薬液７を注射針３側に吐出し、この結果、注射針３を介して体内部位の内部に薬液７を注入する。一方、吐出バルーン８は、この注射針３との連通状態が駆動弁９によって解除された場合または自身の収縮力を消費し尽くした場合、薬液７の吐出（注入）を停止する。   The discharge balloon 8 functions as a liquid injection means for injecting a liquid into the internal body part via the injection needle 3 punctured into the internal body part of the subject. Specifically, the discharge balloon 8 is realized by a stretchable elastic film and attached to the communication tube 10a. The discharge balloon 8 contains the drug solution 7 in an inflated state and stores the drug solution 7. The inside of the discharge balloon 8 communicates with the communication tube 10a, and communicates with the injection needle 3 through the communication tube 10a, the tube 10b, and the like when a drive valve 9 described later is in an open state. When the discharge balloon 8 is in communication with the injection needle 3, the discharge balloon 8 discharges the drug solution 7 to the injection needle 3 side by its own contraction force, and as a result, the drug solution 7 is injected into the body part via the injection needle 3. . On the other hand, the discharge balloon 8 stops the discharge (injection) of the drug solution 7 when the communication state with the injection needle 3 is released by the drive valve 9 or when the contraction force of the discharge balloon 8 is exhausted.

駆動弁９は、電磁弁等を用いて実現され、制御部１３の制御に基づいて開閉駆動する。駆動弁９は、連通管１０ａおよびチューブ１０ｂと連通接続され、連通管１０ａを介して吐出バルーン８と連通し、且つチューブ１０ｂを介して注射針３と連通する。かかる駆動弁９は、開駆動を行って開状態に切り替わった場合、連通管１０ａおよびチューブ１０ｂを介して吐出バルーン８と注射針３とを連通状態にし、閉駆動を行って閉状態に切り替わった場合、かかる吐出バルーン８と注射針３との連通状態を遮断する。   The drive valve 9 is realized by using an electromagnetic valve or the like, and is driven to open and close based on the control of the control unit 13. The drive valve 9 is connected to the communication tube 10a and the tube 10b, communicates with the discharge balloon 8 through the communication tube 10a, and communicates with the injection needle 3 through the tube 10b. When the drive valve 9 is opened and switched to the open state, the discharge balloon 8 and the injection needle 3 are connected to each other via the communication tube 10a and the tube 10b, and the drive valve 9 is switched to the closed state by performing the closed drive. In this case, the communication state between the discharge balloon 8 and the injection needle 3 is blocked.

なお、かかる駆動弁９と注射針３とを連通可能に接続するチューブ１０ｂは、可撓性のチューブ部材であってもよいし、伸縮自在な弾性部材からなるチューブ部材であってもよい。また、かかるチューブ１０ｂの長さは、上述した注射針３の突没動作を阻害しない程度の長さであればよい。   The tube 10b that connects the drive valve 9 and the injection needle 3 so as to communicate with each other may be a flexible tube member or a tube member made of an elastic member that can be expanded and contracted. Moreover, the length of this tube 10b should just be a length of the grade which does not inhibit the protrusion and subtraction operation | movement of the injection needle 3 mentioned above.

撮像部１１は、被検体の体内画像を撮像するためのものである。具体的には、撮像部１１は、ＬＥＤ等の照明部１１ａと、集光レンズ等の光学系１１ｂと、ＣＣＤまたはＣＭＯＳイメージセンサ等の固体撮像素子１１ｃとを備える。撮像部１１は、カプセル型筐体２に対する所定の相対方向の軸（例えばカプセル型筐体２の長手方向の中心軸ＣＬ）と光学系１１ｂの光軸とを一致させる態様でカプセル型筐体２の内部に固定配置され、カプセル型筐体２の長手方向等の所定の方向に撮像視野を向ける。かかる撮像部１１において、１以上（望ましくは複数）の照明部１１ａは、撮像部１１の被写体である被検体の臓器内部を照明する。光学系１１ｂは、照明部１１ａによって照明された被写体からの反射光を集光し、固体撮像素子１１ｃの受光面に、この被写体の光学像を結像する。固体撮像素子１１ｃは、光学系１１ｂによって結像された被写体の光学像、すなわち被検体の体内画像を撮像する。かかる撮像部１１は、この固体撮像素子１１ｃの光電変換処理によって生成された信号を制御部１３に送信する。   The imaging unit 11 is for capturing an in-vivo image of the subject. Specifically, the imaging unit 11 includes an illumination unit 11a such as an LED, an optical system 11b such as a condenser lens, and a solid-state imaging element 11c such as a CCD or CMOS image sensor. The imaging unit 11 is configured in such a manner that an axis in a predetermined relative direction with respect to the capsule casing 2 (for example, a central axis CL in the longitudinal direction of the capsule casing 2) and an optical axis of the optical system 11b are matched. The imaging field of view is directed in a predetermined direction such as the longitudinal direction of the capsule housing 2. In the imaging unit 11, one or more (preferably plural) illumination units 11 a illuminate the inside of the organ of the subject that is the subject of the imaging unit 11. The optical system 11b condenses the reflected light from the subject illuminated by the illumination unit 11a and forms an optical image of the subject on the light receiving surface of the solid-state imaging device 11c. The solid-state imaging device 11c captures an optical image of the subject imaged by the optical system 11b, that is, an in-vivo image of the subject. The imaging unit 11 transmits a signal generated by the photoelectric conversion process of the solid-state imaging element 11c to the control unit 13.

通信部１２は、被検体外部に配置された画像表示装置等の外部装置（図示せず）と無線通信を行う。具体的には、通信部１２は、無線アンテナ（図示せず）を備え、この無線アンテナを介して無線信号を送受信する。より具体的には、通信部１２は、制御部１３の制御に基づいて、上述した撮像部１１が撮像した被検体の体内画像を被検体外部の外部装置に無線送信する。この場合、通信部１２は、制御部１３から取得した画像信号（体内画像のデータを含む信号）に対して変調処理等を行って、この画像信号を含む無線信号を生成する。通信部１２は、この生成した無線信号を無線アンテナを介して被検体外部の外部装置に送信する。一方、通信部１２は、制御部１３の制御に基づいて、被検体外部の外部装置から送信された無線信号を受信し、この受信した無線信号に対して復調処理等を行って、この無線信号から制御信号を抽出する。通信部１２は、かかる外部装置からの制御信号を制御部１３に送信する。   The communication unit 12 performs wireless communication with an external device (not shown) such as an image display device arranged outside the subject. Specifically, the communication unit 12 includes a wireless antenna (not shown), and transmits / receives a wireless signal via the wireless antenna. More specifically, the communication unit 12 wirelessly transmits the in-vivo image of the subject imaged by the imaging unit 11 described above to an external device outside the subject based on the control of the control unit 13. In this case, the communication unit 12 performs a modulation process or the like on the image signal (a signal including in-vivo image data) acquired from the control unit 13 to generate a radio signal including the image signal. The communication unit 12 transmits the generated wireless signal to an external device outside the subject via a wireless antenna. On the other hand, the communication unit 12 receives a radio signal transmitted from an external device outside the subject based on the control of the control unit 13, performs a demodulation process on the received radio signal, and the like. A control signal is extracted from The communication unit 12 transmits a control signal from the external device to the control unit 13.

制御部１３は、予め設定されたプログラムを実行するＣＰＵと、各種データ等を記憶するＲＯＭと、演算パラメータ等を記憶するＲＡＭとを用いて実現される。制御部１３は、カプセル型医療装置１の各構成部（具体的には、加熱部４、駆動部６、駆動弁９、撮像部１１および通信部１２等）を制御し、且つ、かかる各構成部間における信号の入出力を制御する。また、制御部１３は、駆動弁９の制御を通して、上述した吐出バルーン８の吐出動作（注入動作）を制御する。かかる制御部１３は、通信部１２を介して取得した外部装置からの制御信号に基づいて加熱部４と駆動部６と駆動弁９とを適宜制御し、これによって、被検体の体内部位に注射針３を穿刺してから、この体内部位の内部への薬液７の注射を経て、この注射完了した体内部位から注射針３を抜き取ってカプセル型筐体２の内部に収納するまでの一連の動作を制御する。なお、かかる一連の動作には、加熱部４による注射針３の加熱処理（すなわち体内部位の穿刺穴の閉塞処理）、駆動部６による注射針３の突没動作および吐出バルーン８による薬液７の吐出（注入）動作が含まれる。   The control unit 13 is realized using a CPU that executes a preset program, a ROM that stores various data and the like, and a RAM that stores calculation parameters and the like. The control unit 13 controls each component of the capsule medical device 1 (specifically, the heating unit 4, the drive unit 6, the drive valve 9, the imaging unit 11, the communication unit 12, and the like) and each of the components. Controls input and output of signals between parts. Further, the control unit 13 controls the discharge operation (injection operation) of the discharge balloon 8 described above through the control of the drive valve 9. The control unit 13 appropriately controls the heating unit 4, the drive unit 6, and the drive valve 9 based on a control signal from the external device acquired via the communication unit 12, thereby injecting the body part of the subject. A series of operations from the puncture of the needle 3 through the injection of the medicinal solution 7 into the internal part of the body, the extraction of the injection needle 3 from the internal part of the injection completed, and the storage of the inside of the capsule housing 2 To control. The series of operations includes a heating process of the injection needle 3 by the heating unit 4 (that is, a process of closing the puncture hole in the body part), a projecting and retracting operation of the injection needle 3 by the driving unit 6, and A discharge (injection) operation is included.

また、制御部１３は、画像処理部１３ａを備える。制御部１３は、照明部１１ａが照明した被写体の画像（被検体の体内画像）を固体撮像素子１１ｃが撮像するように撮像部１１の動作タイミングを制御する。画像処理部１３ａは、かかる撮像部１１の固体撮像素子１１ｃによって光電変換された信号を取得し、この取得した信号に対して所定の信号処理を行って、被検体の体内画像のデータを含む画像信号を生成する。制御部１３は、かかる画像処理部１３ａによって生成された画像信号、すなわち撮像部１１が撮像した被検体の体内画像のデータを含む画像信号を被検体外部の外部装置に無線送信するように通信部１２を制御する。制御部１３は、画像処理部１３ａが画像信号を生成する都度（すなわち撮像部１１が被検体の体内画像を撮像する都度）、かかる通信部１２の制御を繰り返す。一方、制御部１３は、通信部１２を制御して被検体外部の外部装置からの制御信号を取得する。   The control unit 13 includes an image processing unit 13a. The control unit 13 controls the operation timing of the imaging unit 11 so that the solid-state imaging device 11c captures an image of the subject illuminated by the illumination unit 11a (in-vivo image of the subject). The image processing unit 13a acquires a signal photoelectrically converted by the solid-state imaging device 11c of the imaging unit 11, performs predetermined signal processing on the acquired signal, and includes an in-vivo image data of the subject. Generate a signal. The control unit 13 wirelessly transmits an image signal generated by the image processing unit 13a, that is, an image signal including in-vivo image data of the subject captured by the imaging unit 11 to an external device outside the subject. 12 is controlled. The control unit 13 repeats the control of the communication unit 12 every time the image processing unit 13a generates an image signal (that is, every time the imaging unit 11 captures an in-vivo image of the subject). On the other hand, the control unit 13 controls the communication unit 12 to acquire a control signal from an external device outside the subject.

電源部１４は、スイッチ部およびボタン型の電池等を用いて実現され、スイッチ部によってオン状態に切り替わった場合、上述した加熱部４、駆動部６、駆動弁９、撮像部１１、通信部１２および制御部１３に対して電力を適宜供給する。また、電源部１４は、スイッチ部によってオフ状態に切り替わった場合、かかる制御部１３等の各構成部に対する電力供給を停止する。なお、かかる電源部１４のスイッチ部は、外部から印加された磁界の作用によってオンオフ状態を切り替える磁気スイッチであってもよいし、外部から入射された赤外光等の所定の光信号に基づいてオンオフ状態を切り替える光スイッチであってもよい。   The power supply unit 14 is realized using a switch unit, a button-type battery, and the like. When the switch unit is turned on, the heating unit 4, the drive unit 6, the drive valve 9, the imaging unit 11, and the communication unit 12 described above. In addition, power is appropriately supplied to the control unit 13. Moreover, the power supply part 14 stops the electric power supply with respect to each structure parts, such as this control part 13, when switched to an OFF state by a switch part. The switch unit of the power supply unit 14 may be a magnetic switch that switches on and off by the action of a magnetic field applied from the outside, or based on a predetermined optical signal such as infrared light incident from the outside. An optical switch that switches between on and off states may be used.

以上のような構成を有するカプセル型医療装置１は、経口摂取等によって被検体の臓器内部に導入され、その後、蠕動運動等によって被検体の臓器内部（消化管内部）を移動する。かかる被検体内部のカプセル型医療装置１は、撮像部１１によって被検体の体内画像を所定の時間間隔（例えば０．５秒間隔）で順次撮像し、通信部１２によって体内画像の画像信号を被検体外部の外部装置に順次無線送信する。   The capsule medical device 1 having the above-described configuration is introduced into the subject's organ by oral ingestion or the like, and then moves inside the subject's organ (inside the digestive tract) by peristalsis or the like. The capsule medical device 1 inside the subject sequentially captures in-vivo images of the subject at predetermined time intervals (for example, at intervals of 0.5 seconds) by the imaging unit 11, and receives an image signal of the in-vivo images by the communication unit 12. Sequentially wirelessly transmit to an external device outside the sample.

また、被検体内部のカプセル型医療装置１は、このように被検体の体内画像を順次撮像および無線送信しつつ被検体の臓器内部を順次移動し、薬液７を注射すべき所望の体内部位に到達する。この体内部位に到達したカプセル型医療装置１は、この体内部位に注射針３を穿刺して薬液７を注射し、この薬液７を注入してから注射針３を抜き取るまでの期間に、この体内部位の穿刺穴を閉塞状態にする。その後、このカプセル型医療装置１は、この体内部位から注射針３を抜き取ってカプセル型筐体２の内部に注射針３を収納し、この体内部位に薬液７を注射するための一連の動作を終了する。かかるカプセル型医療装置１は、この注射針３をカプセル型筐体２の内部に収納後、被検体の臓器内部を移動し、最終的に、被検体の外部に排出される。   In addition, the capsule medical device 1 inside the subject sequentially moves in the organ of the subject while sequentially capturing and wirelessly transmitting in-vivo images of the subject in this manner, and moves to the desired in-vivo site where the drug solution 7 is to be injected. To reach. The capsule-type medical device 1 that has reached the internal body part punctures the injection needle 3 into the internal body part, injects the liquid medicine 7, and injects the medical liquid 7 until the injection needle 3 is removed. The puncture hole at the site is closed. Thereafter, the capsule medical device 1 performs a series of operations for extracting the injection needle 3 from the body part, storing the injection needle 3 in the capsule housing 2, and injecting the drug solution 7 into the body part. finish. The capsule medical device 1 moves the inside of the organ of the subject after storing the injection needle 3 in the capsule housing 2 and is finally discharged to the outside of the subject.

つぎに、被検体内部における所望部位の一例である患部に薬液を注射する場合を例示して、本発明の実施の形態１にかかるカプセル型医療装置１の動作を具体的に説明する。図２は、被検体内部のカプセル型医療装置が患部に到達する状態を示す模式図である。図３は、被検体内部のカプセル型医療装置が患部に薬液を注射する状態を示す模式図である。図４は、注射針の縮小変形によって体内部位の穿刺穴が閉塞する状態を示す模式図である。図５は、縮小変形した注射針がカプセル型筐体の内部に収納される状態を示す模式図である。   Next, the operation of the capsule medical device 1 according to the first embodiment of the present invention will be specifically described by exemplifying a case where a drug solution is injected into an affected part, which is an example of a desired site inside the subject. FIG. 2 is a schematic diagram showing a state in which the capsule medical device inside the subject reaches the affected area. FIG. 3 is a schematic diagram showing a state in which a capsule medical device inside a subject injects a drug solution into an affected area. FIG. 4 is a schematic diagram showing a state in which the puncture hole in the body part is closed by the reduction deformation of the injection needle. FIG. 5 is a schematic diagram showing a state where the reduced-sized deformed injection needle is accommodated in the capsule-type housing.

カプセル型医療装置１は、上述したように、経口摂取等によって患者等の被検体の臓器内部に導入される。かかる被検体内部のカプセル型医療装置１は、図２に示すように、この被検体の体内画像の撮像および無線送信を順次繰り返しつつ、蠕動運動等によって消化管内部を移動して患部１５の近傍に到達する（状態Ａ１）。この場合、カプセル型医療装置１は、撮像部１１によって撮像した体内画像を被検体外部の外部装置に無線送信する。この外部装置は、かかるカプセル型医療装置１から受信した体内画像をディスプレイに表示する。医師または看護師等のユーザは、この外部装置の表示情報を視認することによって、被検体内部のカプセル型医療装置１が患部１５の近傍に到達したことを確認する。   As described above, the capsule medical device 1 is introduced into an organ of a subject such as a patient by ingestion or the like. As shown in FIG. 2, the capsule medical device 1 inside the subject moves in the digestive tract by peristaltic motion or the like while sequentially taking in-vivo images and wireless transmission of the subject, and in the vicinity of the affected part 15. (State A1). In this case, the capsule medical device 1 wirelessly transmits the in-vivo image captured by the imaging unit 11 to an external device outside the subject. The external device displays the in-vivo image received from the capsule medical device 1 on the display. A user such as a doctor or nurse confirms that the capsule medical device 1 inside the subject has reached the vicinity of the affected part 15 by visually recognizing the display information of the external device.

かかる患部１５近傍のカプセル型医療装置１は、蠕動運動等によって患部１５の位置に到達し、図２に示すように注射針３の位置と患部１５の位置とを合わせる（状態Ａ２）。なお、ユーザは、外部装置の表示情報を視認することによって、このように被検体内部のカプセル型医療装置１が患部１５の位置に到達した旨を確認する。   The capsule medical device 1 in the vicinity of the affected part 15 reaches the position of the affected part 15 by a peristaltic motion or the like, and aligns the position of the injection needle 3 and the affected part 15 as shown in FIG. 2 (state A2). In addition, the user confirms that the capsule medical device 1 inside the subject has reached the position of the affected area 15 by visually recognizing display information of the external device.

ここで、外部装置は、ユーザによる操作に対応して、カプセル型医療装置１に対する制御信号を生成し、この生成した制御信号を被検体内部の被検体１に無線送信する。被検体内部のカプセル型医療装置１は、上述した通信部１２によって外部装置からの制御信号を受信し、この受信した制御信号に基づいて、患部１５に注射針３を穿刺してから患部１５の内部に薬液７を注射してカプセル型筐体２の内部に注射針３を収納するまでの一連の動作を実行する。   Here, the external device generates a control signal for the capsule medical device 1 in response to an operation by the user, and wirelessly transmits the generated control signal to the subject 1 inside the subject. The capsule medical device 1 inside the subject receives the control signal from the external device through the communication unit 12 described above, and punctures the injection needle 3 in the affected part 15 based on the received control signal and A series of operations from the time when the drug solution 7 is injected to the time when the injection needle 3 is housed inside the capsule housing 2 is executed.

かかるカプセル型医療装置１において、制御部１３は、上述した外部装置からの制御信号に基づいて、まず、カプセル型筐体２から注射針３を突き出すように駆動部６を制御する。この場合、駆動部６は、開口部２ｃ側に向かう方向に支持部５を移動する。かかる支持部５に支持された注射針３は、図３に示すように、開口部２ｃを通ってカプセル型筐体２から突出し、患部１５に突き刺さる（状態Ａ３）。この場合、チューブ１０ｂは、かかる注射針３の突出動作を阻害しない。また、加熱部４は、患部１５への注射針３の穿刺を阻害することなく、この注射針３の外壁面に固定された状態を維持する。   In the capsule medical device 1, the control unit 13 first controls the drive unit 6 so as to protrude the injection needle 3 from the capsule housing 2 based on the control signal from the external device described above. In this case, the drive unit 6 moves the support unit 5 in a direction toward the opening 2c side. As shown in FIG. 3, the injection needle 3 supported by the support portion 5 protrudes from the capsule-type housing 2 through the opening 2c and pierces the affected area 15 (state A3). In this case, the tube 10b does not hinder the protruding operation of the injection needle 3. Further, the heating unit 4 maintains a state of being fixed to the outer wall surface of the injection needle 3 without hindering the puncture of the injection needle 3 to the affected part 15.

つぎに、制御部１３は、患部１５に注射針３を穿刺し終えたタイミングに駆動弁９を制御し、この駆動弁９の制御を通して吐出バルーン８による薬液７の吐出動作を開始する。この場合、駆動弁９は、開駆動を行うことによって、連通管１０ａおよびチューブ１０ｂを介して吐出バルーン８と注射針３とを連通状態に切り替る。吐出バルーン８は、かかる連通管１０ａ、駆動弁９およびチューブ１０ｂの内部に薬液７を流通させ、患部１５に穿刺した状態の注射針３を介して患部１５の内部に薬液７を注入する。かかる注射針３を介して吐出された薬液７は、図３に示すように、患部１５の内部を伸展しつつ患部１５の内部に注入される（状態Ａ４）。   Next, the control unit 13 controls the drive valve 9 at the timing when the injection needle 3 has been punctured into the affected part 15 and starts the discharge operation of the drug solution 7 by the discharge balloon 8 through the control of the drive valve 9. In this case, the drive valve 9 switches the discharge balloon 8 and the injection needle 3 to the communication state via the communication tube 10a and the tube 10b by performing an opening drive. The discharge balloon 8 circulates the drug solution 7 through the communication tube 10a, the drive valve 9 and the tube 10b, and injects the drug solution 7 into the diseased part 15 through the injection needle 3 punctured in the diseased part 15. As shown in FIG. 3, the drug solution 7 discharged through the injection needle 3 is injected into the affected area 15 while extending inside the affected area 15 (state A4).

かかる制御部１３は、このように患部１５に注射針３を穿刺した状態を維持しつつ、この注射針３を介して患部１５に薬液７を注入し始めてから所定の時間が経過したタイミングに、注射針３と吐出バルーン８との連通状態を遮断するように駆動弁９を制御する。この場合、駆動弁９は、閉駆動を行うことによって注射針３と吐出バルーン８との連通状態を遮断する。これによって、吐出バルーン８による患部１５への薬液７の注入動作が終了する。なお、制御部１３は、かかる駆動弁９の切替タイミングを制御することによって、吐出バルーン８による薬液７の吐出量（注入量）を患部１５に必要な液量に制御できる。   The control unit 13 maintains the state where the injection needle 3 is punctured in the affected part 15 as described above, and at a timing when a predetermined time has elapsed since the start of injecting the drug solution 7 into the affected part 15 through the injection needle 3. The drive valve 9 is controlled so as to block the communication state between the injection needle 3 and the discharge balloon 8. In this case, the drive valve 9 shuts off the communication state between the injection needle 3 and the discharge balloon 8 by performing a closed drive. Thereby, the injection operation of the drug solution 7 into the affected part 15 by the discharge balloon 8 is completed. The control unit 13 can control the discharge amount (injection amount) of the drug solution 7 from the discharge balloon 8 to a liquid amount necessary for the affected part 15 by controlling the switching timing of the drive valve 9.

このように吐出バルーン８が薬液７の注入動作を終了した状態において、制御部１３は、加熱部４に電力を印加して注射針３の加熱処理を制御する。この場合、加熱部４は、かかる制御部１３から供給された電力をもとに発熱し始め、患部１５に穿刺した状態の注射針３を加熱処理する。かかる加熱部４によって加熱処理された注射針３は、患部１５に穿刺した状態を維持しつつ、所定の温度以上（少なくとも体温を超過する温度）に加熱されて軟化する。このように軟化した注射針３は、図４に示すように、中空針としての外形を維持した状態（状態Ａ５）から患部１５の収縮力によって縮小変形した状態になる（状態Ａ６）。この結果、注射針３による患部１５の穿刺穴１６は、その開口径を最小化した状態になり、内部の薬液７を外部に漏出させない状態、すなわち閉塞状態になる。   Thus, in a state where the discharge balloon 8 has finished the injection operation of the drug solution 7, the control unit 13 applies power to the heating unit 4 to control the heating process of the injection needle 3. In this case, the heating unit 4 starts to generate heat based on the electric power supplied from the control unit 13 and heats the injection needle 3 in a state where the affected part 15 is punctured. The injection needle 3 heat-treated by the heating unit 4 is heated to a predetermined temperature or higher (at least the temperature exceeding the body temperature) and softens while maintaining the state where the affected part 15 is punctured. As shown in FIG. 4, the softened injection needle 3 is in a state of being reduced and deformed by the contraction force of the affected area 15 (state A6) from a state in which the outer shape as a hollow needle is maintained (state A5). As a result, the puncture hole 16 of the affected area 15 by the injection needle 3 is in a state in which the opening diameter is minimized, and the internal drug solution 7 is not leaked to the outside, that is, is closed.

かかる制御部１３は、加熱部４に注射針３を加熱処理させてから所定の時間が経過したタイミング（すなわち、穿刺状態の注射針３が患部１５の収縮力によって十分に縮小変形したタイミング）に、この注射針３の加熱処理を停止するように加熱部４を制御する。加熱部４は、制御部１３による電力供給を停止され、これによって注射針３の加熱処理を終了する。   The control unit 13 performs the timing at which a predetermined time has elapsed since the heating unit 4 heat-processed the injection needle 3 (that is, the timing when the injection needle 3 in the puncture state is sufficiently reduced and deformed by the contraction force of the affected part 15). The heating unit 4 is controlled so as to stop the heat treatment of the injection needle 3. The heating unit 4 is stopped from supplying power by the control unit 13, thereby ending the heating process of the injection needle 3.

その後、制御部１３は、このように注射針３が十分に縮小変形したタイミング（すなわち患部１５の穿刺穴１６が閉塞状態になったタイミング）に、カプセル型筐体２の内部に注射針３を収納するように駆動部６を制御する。この場合、駆動部６は、開口部２ｃから離間する方向に支持部５を移動して、患部１５から注射針３を抜き取り、カプセル型筐体２の内部に注射針３を収納する（状態Ａ７）。   Thereafter, the control unit 13 places the injection needle 3 in the capsule housing 2 at the timing when the injection needle 3 is sufficiently reduced and deformed in this way (that is, the timing when the puncture hole 16 of the affected part 15 is closed). The drive unit 6 is controlled so as to be stored. In this case, the drive unit 6 moves the support unit 5 in a direction away from the opening 2c, extracts the injection needle 3 from the affected part 15, and stores the injection needle 3 in the capsule housing 2 (state A7). ).

ここで、注射針３を抜き取られた患部１５の穿刺穴（穿刺跡）１６は、上述したように閉塞状態である。このため、患部１５は、このように注射針３が抜き取られた後であっても、この穿刺穴１６から薬液７を漏出させることなく、内部に薬液７を留める。この結果、患部１５内部の薬液７は、この被検体内部における患部１５以外の体内部位に漏れ広がることがない。   Here, the puncture hole (puncture mark) 16 of the affected part 15 from which the injection needle 3 has been extracted is in the closed state as described above. For this reason, even after the injection needle 3 is pulled out in this way, the affected part 15 keeps the drug solution 7 inside without leaking the drug solution 7 from the puncture hole 16. As a result, the medicinal solution 7 inside the affected part 15 does not leak and spread in the body part other than the affected part 15 inside the subject.

以上、説明したように、本発明の実施の形態１では、体内部位に穿刺する注射針が熱可塑性樹脂によって形成され、吐出バルーンが、体内部位に穿刺した状態の注射針を介してこの体内部位の内部に薬液を注入し、加熱部が、この穿刺状態の注射針を加熱処理によって軟化し、この軟化した注射針が、体内部位の収縮力によって容易に縮小変形し、これによって、この体内部位の穿刺穴を閉塞状態にするように構成した。このため、体内部位に注射針を穿刺した状態を維持しつつ、この穿刺状態の注射針の縮小変形に伴って体内部位の穿刺穴の開口径を縮小し、これによって、この体内部位の穿刺穴から薬液等の注入液体を漏出させることなく、この穿刺穴を閉塞状態に変化することができ、この結果、薬液注射後の体内部位から注射針を抜き取った後に、この体内部位から薬液が漏れ出ることを防止できるカプセル型医療装置を実現することができる。   As described above, in the first embodiment of the present invention, the injection needle that punctures the internal body part is formed of a thermoplastic resin, and the discharge balloon is inserted into the internal body part via the injection needle in the state of puncturing the internal body part. The medical solution is injected into the inside of the body, and the heating unit softens the punctured injection needle by heat treatment, and the softened injection needle is easily contracted and deformed by the contraction force of the internal body part. The puncture hole was closed. For this reason, while maintaining the state where the injection needle is punctured into the internal body part, the opening diameter of the puncture hole in the internal body part is reduced in accordance with the contraction deformation of the injection needle in the puncture state, and thereby the puncture hole of the internal body part The puncture hole can be changed to a closed state without causing the injection liquid such as the drug solution to leak from, and as a result, the drug solution leaks from the internal site after the injection needle is removed from the internal site after the drug solution is injected. It is possible to realize a capsule medical device that can prevent this.

本発明にかかるカプセル型医療装置を用いることによって、被検体内部における患部等の所望部位に注射した薬液がこの所望部位の穿刺穴から漏れ出ることを防止できるため、この所望部位以外の体内部位（すなわち目的外の体内部位）に薬液が広がって、この目的外の体内部位に対して意図せずに薬液が作用することを防止できる。特に、薬液が有色の液体である場合、本発明によれば、かかる効果に加えて、この所望部位から漏れ出た有色の薬液がカプセル型医療装置の外壁面に付着してカプセル型医療装置の視界（撮像視野）を妨げることをさらに防止できる。   By using the capsule medical device according to the present invention, it is possible to prevent the drug solution injected into a desired site such as an affected area inside the subject from leaking from the puncture hole of the desired site. That is, it is possible to prevent the drug solution from spreading to the body part outside the target) and unintentionally acting on the body part outside the purpose. In particular, when the drug solution is a colored liquid, according to the present invention, in addition to this effect, the colored drug solution leaking from the desired site adheres to the outer wall surface of the capsule medical device and Further obstructing the field of view (imaging field of view) can be further prevented.

（実施の形態２）
つぎに、本発明の実施の形態２について説明する。上述した実施の形態１では、体内部位に穿刺した状態の注射針３を加熱処理によって縮小変形させて、この注射針３による体内部位の穿刺穴を閉塞状態にしていたが、この実施の形態２では、注射針の外壁部に摺動可能に軟質管を外嵌し、この軟質管とともに注射針を体内部位に穿刺して薬液を注射した後、この体内部位の穿刺穴に軟質管を残して注射針を抜き取り、この軟質管を体内部位の収縮力によって縮小変形させることによって、この穿刺穴を閉塞状態にしている。 (Embodiment 2)
Next, a second embodiment of the present invention will be described. In the first embodiment described above, the injection needle 3 that has been punctured into the body part is contracted and deformed by heat treatment so that the puncture hole in the body part by the injection needle 3 is in a closed state. Then, a soft tube is slidably fitted on the outer wall of the injection needle, and after the injection needle is punctured into the body part together with this soft tube and the drug solution is injected, the soft tube is left in the puncture hole of the body part. The puncture hole is closed by pulling out the injection needle and reducing the deformation of the soft tube by the contraction force of the internal region.

図６は、本発明の実施の形態２にかかるカプセル型医療装置の一構成例を示す模式図である。図６に示すように、この実施の形態２にかかるカプセル型医療装置２１は、上述した実施の形態１にかかるカプセル型医療装置１の注射針３に代えて注射針２３を備え、制御部１３に代えて制御部２９を備える。また、カプセル型医療装置２１は、この注射針２３に摺動可能に外嵌する薄膜チューブ２４と、この薄膜チューブ２４を支持する支持部２５と、この支持部２５を介して薄膜チューブ２４を直線的に往復動作する駆動部２６とを備える。その他の構成は実施の形態１と同じであり、同一構成部分には同一符号を付している。   FIG. 6 is a schematic diagram illustrating a configuration example of a capsule medical apparatus according to the second embodiment of the present invention. As shown in FIG. 6, the capsule medical device 21 according to the second embodiment includes an injection needle 23 instead of the injection needle 3 of the capsule medical device 1 according to the first embodiment described above, and includes a control unit 13. Instead of this, a control unit 29 is provided. In addition, the capsule medical device 21 includes a thin film tube 24 that is slidably fitted to the injection needle 23, a support portion 25 that supports the thin film tube 24, and the thin film tube 24 that is straight through the support portion 25. And a drive unit 26 that reciprocally moves. Other configurations are the same as those of the first embodiment, and the same reference numerals are given to the same components.

注射針２３は、金属等によって形成される硬質の中空針であり、穿刺した体内部位の収縮力によって縮小変形するものではない。また、注射針２３の後端部にはチューブ１０ｂが取り付けられ、注射針２３は、このチューブ１０ｂを介して駆動弁９と連通する。この注射針２３の後端部近傍には支持部５が取り付けられ、注射針２３は、上述した実施の形態１における注射針３と同様に駆動部６の作用によってカプセル型筐体２から突没する。なお、注射針２３は、上述した実施の形態１における注射針３と同様の中空針構造を有する。   The injection needle 23 is a hard hollow needle formed of metal or the like, and does not shrink and deform due to the contraction force of the punctured body part. A tube 10b is attached to the rear end portion of the injection needle 23, and the injection needle 23 communicates with the drive valve 9 via the tube 10b. The support portion 5 is attached in the vicinity of the rear end portion of the injection needle 23, and the injection needle 23 protrudes and retracts from the capsule-type housing 2 by the action of the drive portion 6 in the same manner as the injection needle 3 in the first embodiment described above. To do. The injection needle 23 has a hollow needle structure similar to the injection needle 3 in the first embodiment described above.

薄膜チューブ２４は、軟質の樹脂性薄膜によって形成される軟質管であり、上述した注射針２３の外径寸法と略同じ内径寸法を有する。この薄膜チューブ２４の後端部近傍には支持部２５が固定される。支持部２５は、カプセル型筐体２の開口部２ｃを通して薄膜チューブ２４が突没可能な態様で薄膜チューブ２４を支持する。かかる薄膜チューブ２４は、注射針２３の外壁部に摺動可能に外嵌し、体内部位に穿刺する注射針２３とともに、この体内部位の穿刺穴に入り込む。このように穿刺穴の内部に入り込んだ状態の薄膜チューブ２４は、注射針２３に外嵌した状態において管形状を維持し、注射針２３が抜き取られた状態において体内部位の収縮力によって容易に押し潰されて縮小変形する。   The thin film tube 24 is a soft tube formed of a soft resinous thin film, and has an inner diameter dimension substantially the same as the outer diameter dimension of the injection needle 23 described above. A support portion 25 is fixed near the rear end portion of the thin film tube 24. The support portion 25 supports the thin film tube 24 in such a manner that the thin film tube 24 can project and retract through the opening 2 c of the capsule housing 2. The thin film tube 24 is slidably fitted to the outer wall portion of the injection needle 23, and enters the puncture hole of the internal body part together with the injection needle 23 that punctures the internal body part. Thus, the thin-film tube 24 that has entered the inside of the puncture hole maintains a tubular shape when it is externally fitted to the injection needle 23, and is easily pushed by the contraction force of the internal body part when the injection needle 23 is removed. Shrink and deform.

駆動部２６は、注射針２３を突没させる駆動部６とは独立して動作可能なものであり、カプセル型筐体２の開口部２ｃを介して薄膜チューブ２４を突没させる管駆動手段として機能する。具体的には、駆動部２６は、リニアアクチュエータ等を用いて実現され、薄膜チューブ２４の支持部２５と接続される。駆動部２６は、支持部２５を介して薄膜チューブ２４を注射針２３の突没方向（図６に示す太線矢印方向）と同じ方向に往復動作させる。かかる駆動部２６は、制御部２９の制御に基づいて、注射針２３とともに薄膜チューブ２４を体内部位に向けて突出させ、上述した駆動部６が体内部位から注射針２３を抜き取るまでの期間、この体内部位の穿刺穴に薄膜チューブ２４を留める。また、かかる駆動部２６は、制御部２９の制御に基づいて、この注射針２３の抜き取り後に体内部位から薄膜チューブ２４を抜き取って、カプセル型筐体２の内部に薄膜チューブ２４を収納する。   The drive unit 26 is operable independently of the drive unit 6 for projecting and retracting the injection needle 23, and serves as tube driving means for projecting and retracting the thin-film tube 24 through the opening 2 c of the capsule housing 2. Function. Specifically, the drive unit 26 is realized using a linear actuator or the like, and is connected to the support unit 25 of the thin film tube 24. The drive unit 26 causes the thin film tube 24 to reciprocate in the same direction as the protruding and retracting direction of the injection needle 23 (thick arrow direction shown in FIG. 6) via the support unit 25. Based on the control of the control unit 29, the driving unit 26 causes the thin-film tube 24 to protrude toward the body part together with the injection needle 23, and during this period until the driving unit 6 extracts the injection needle 23 from the body part. The thin film tube 24 is fastened to the puncture hole in the body part. Further, the drive unit 26 extracts the thin film tube 24 from the body part after extracting the injection needle 23 based on the control of the control unit 29, and stores the thin film tube 24 inside the capsule housing 2.

ここで、注射針２３とともに体内部位の穿刺穴に入り込んだ薄膜チューブ２４は、穿刺状態の注射針２３に外嵌した状態であれば、この穿刺穴の内部において生体組織に押し潰されることなく、その管形状を維持する。一方、かかる穿刺穴内部の薄膜チューブ２４は、上述した駆動部６によって体内部位から注射針２３が徐々に抜き取られるとともに中空部分を徐々に狭め、最終的に、この体内部位の収縮力によって縮小変形（例えば圧潰変形）して、この穿刺穴を閉塞状態にする。すなわち、かかる薄膜チューブ２４および駆動部２６は、注射針２３による体内部位の穿刺穴の開口径を最小化してこの穿刺穴を閉塞状態にする閉塞手段として機能する。   Here, the thin-film tube 24 that has entered the puncture hole in the body part together with the injection needle 23 is not crushed by the living tissue inside the puncture hole, as long as the thin-film tube 24 is externally fitted to the injection needle 23 in the puncture state. Maintain its tube shape. On the other hand, the thin-film tube 24 inside the puncture hole gradually pulls out the injection needle 23 from the body part by the driving unit 6 and gradually narrows the hollow part, and finally shrinks and deforms due to the contraction force of the body part. (For example, crush deformation) to make this puncture hole closed. That is, the thin film tube 24 and the drive unit 26 function as a closing unit that minimizes the diameter of the puncture hole in the body part by the injection needle 23 and closes the puncture hole.

制御部２９は、カプセル型筐体２から注射針２３とともに薄膜チューブ２４を突出させるように駆動部２６を制御する。この場合、制御部２９は、注射針２３の突出動作と薄膜チューブ２４の突出動作とを同期して行うように駆動部６および駆動部２６を制御する。また、制御部２９は、駆動部６が体内部位から注射針２３を抜き取るまでの期間、この体内部位の穿刺穴に薄膜チューブ２４を留めるように駆動部２６を制御し、この注射針２３の抜き取り後に体内部位から薄膜チューブ２４を抜き取ってカプセル型筐体２の内部に薄膜チューブ２４を収納するように駆動部２６を制御する。なお、制御部２９は、かかる駆動部２６の動作制御以外、上述した実施の形態１にかかるカプセル型医療装置１の制御部１３と同様の機能を有する。   The control unit 29 controls the drive unit 26 so that the thin film tube 24 is projected together with the injection needle 23 from the capsule housing 2. In this case, the control unit 29 controls the driving unit 6 and the driving unit 26 so that the protruding operation of the injection needle 23 and the protruding operation of the thin film tube 24 are performed in synchronization. Further, the control unit 29 controls the drive unit 26 so that the thin-film tube 24 is fastened to the puncture hole of the internal part during the period until the drive part 6 extracts the injection needle 23 from the internal part. Later, the drive unit 26 is controlled so that the thin film tube 24 is removed from the body part and the thin film tube 24 is accommodated in the capsule housing 2. The control unit 29 has the same functions as those of the control unit 13 of the capsule medical device 1 according to the first embodiment described above, except for the operation control of the driving unit 26.

つぎに、被検体内部における所望部位の一例である患部に薬液を注射する場合を例示して、本発明の実施の形態２にかかるカプセル型医療装置２１の動作を具体的に説明する。図７は、被検体内部のカプセル型医療装置が薄膜チューブとともに注射針を患部に穿刺する状態を示す模式図である。図８は、薄膜チューブの縮小変形によって体内部位の穿刺穴が閉塞する状態を示す模式図である。図９は、薄膜チューブがカプセル型筐体の内部に収納される状態を示す模式図である。なお、この実施の形態２にかかるカプセル型医療装置２１は、上述した実施の形態１にかかるカプセル型医療装置１の場合と同様に患部１５に到達して注射針２３と患部１５との位置を合わせる。   Next, the operation of the capsule medical device 21 according to the second embodiment of the present invention will be specifically described by exemplifying a case where a drug solution is injected into an affected part, which is an example of a desired site inside the subject. FIG. 7 is a schematic view showing a state where the capsule medical device inside the subject punctures the affected area with the injection needle together with the thin film tube. FIG. 8 is a schematic view showing a state in which the puncture hole in the body part is closed by the reduction deformation of the thin film tube. FIG. 9 is a schematic view showing a state in which the thin film tube is housed in the capsule housing. Note that the capsule medical device 21 according to the second embodiment reaches the affected area 15 and positions the injection needle 23 and the affected area 15 in the same manner as the capsule medical apparatus 1 according to the first embodiment described above. Match.

このように被検体内部の患部１５に到達したカプセル型医療装置２１において、制御部２９は、上述した外部装置からの制御信号に基づいて、まず、カプセル型筐体２から薄膜チューブ２４とともに注射針２３を突き出すように駆動部６および駆動部２６を制御する。この場合、駆動部６は、上述した実施の形態１の場合と同様に、カプセル型筐体２の開口部２ｃから注射針２３を突き出して、患部１５に注射針２３を穿刺する。これと同時に、駆動部２６は、この注射針２３の突出に合わせて薄膜チューブ２４を開口部２ｃから突出させる。かかる薄膜チューブ２４は、この注射針２３に外嵌した状態を維持しつつ、この注射針２３とともに患部１５の穿刺穴に入り込む（状態Ｂ３）。   In this way, in the capsule medical device 21 that has reached the affected area 15 inside the subject, the control unit 29 firstly, together with the thin film tube 24 from the capsule housing 2, the injection needle based on the control signal from the external device described above. The drive unit 6 and the drive unit 26 are controlled so as to protrude 23. In this case, the drive unit 6 projects the injection needle 23 from the opening 2c of the capsule housing 2 and punctures the injection needle 23 in the affected area 15 as in the case of the first embodiment described above. At the same time, the drive unit 26 causes the thin film tube 24 to protrude from the opening 2 c in accordance with the protrusion of the injection needle 23. The thin-film tube 24 enters the puncture hole of the affected area 15 together with the injection needle 23 while maintaining the state of being externally fitted to the injection needle 23 (state B3).

つぎに、制御部２９は、薄膜チューブ２４とともに注射針２３を患部１５に穿刺し終えたタイミングに駆動弁９を制御し、この駆動弁９の制御を通して吐出バルーン８による薬液７の吐出動作を開始する。この場合、吐出バルーン８は、上述した実施の形態１の場合と同様に、この穿刺状態の注射針２３を介して患部１５の内部に薬液７を注入する。かかる薬液７は、図７に示すように、患部１５の内部を伸展しつつ患部１５の内部に注入される（状態Ｂ４）。   Next, the control unit 29 controls the drive valve 9 at the timing when the injection needle 23 and the affected part 15 have been punctured together with the thin film tube 24, and starts the discharge operation of the drug solution 7 by the discharge balloon 8 through the control of the drive valve 9. To do. In this case, the discharge balloon 8 injects the medicinal solution 7 into the affected part 15 through the punctured injection needle 23 as in the case of the first embodiment. As shown in FIG. 7, the drug solution 7 is injected into the affected area 15 while extending inside the affected area 15 (state B4).

かかる制御部２９は、この患部１５の穿刺穴に注射針２３と薄膜チューブ２４とを入れた状態を維持しつつ、この注射針２３を介して患部１５に薬液７を注入し始めてから所定の時間が経過したタイミングに、注射針２３と吐出バルーン８との連通状態を遮断するように駆動弁９を制御する。この場合、駆動弁９は、上述した実施の形態１の場合と同様に、閉駆動を行って注射針２３と吐出バルーン８との連通状態を遮断する。吐出バルーン８は、患部１５の内部に必要量の薬液７を注入した後に注入動作を終了する。   The control unit 29 maintains a state where the injection needle 23 and the thin film tube 24 are put in the puncture hole of the affected part 15, and starts a predetermined time after injecting the medicinal solution 7 into the affected part 15 through the injection needle 23. The drive valve 9 is controlled so that the communication state between the injection needle 23 and the discharge balloon 8 is cut off at the timing when elapses. In this case, the drive valve 9 performs a closed drive to block the communication state between the injection needle 23 and the discharge balloon 8 as in the case of the first embodiment described above. The discharge balloon 8 ends the injection operation after injecting a required amount of the drug solution 7 into the affected part 15.

このように吐出バルーン８が薬液７の注入動作を終了した状態において、制御部２９は、患部１５から注射針２３を抜き取るように駆動部６を制御するとともに、この患部１５の穿刺穴１６に薄膜チューブ２４を留めるように駆動部２６を制御する。この場合、注射針２３は、駆動部６の作用によって、薄膜チューブ２４の内部を摺動しつつ、この穿刺穴１６から徐々に抜け出る。一方、薄膜チューブ２４は、駆動部２６の作用によって、かかる注射針２４の抜き取りを阻害せずに穿刺穴１６に留まる（図８参照）。   Thus, in a state where the discharge balloon 8 finishes the injection operation of the drug solution 7, the control unit 29 controls the drive unit 6 so as to extract the injection needle 23 from the affected part 15, and a thin film is formed in the puncture hole 16 of the affected part 15. The drive unit 26 is controlled so that the tube 24 is fastened. In this case, the injection needle 23 is gradually pulled out from the puncture hole 16 while sliding inside the thin film tube 24 by the action of the drive unit 6. On the other hand, the thin-film tube 24 remains in the puncture hole 16 without inhibiting the extraction of the injection needle 24 by the action of the drive unit 26 (see FIG. 8).

ここで、かかる患部１５の穿刺穴１６に留まった状態の薄膜チューブ２４は、注射針２３が穿刺穴１６から完全に抜け出るまでの期間、この注射針２３の抜け出しに伴って内部の中空部分を徐々に狭め、ついには患部１５の生体組織に囲まれた薄膜チューブ２４の一部分（すなわち薄膜チューブ２４の一部分であって穿刺穴１６の内部に入り込んだ部分）が中空状態になる。かかる中空状態である薄膜チューブ２４の一部分は、この患部１５の収縮力によって容易に圧潰変形する（状態Ｂ５）。この結果、注射針２３による患部１５の穿刺穴１６は、その開口径を最小化した状態になり、内部の薬液７を外部に漏出させない状態、すなわち閉塞状態になる。   Here, the thin-film tube 24 in the state where it stays in the puncture hole 16 of the affected part 15 gradually passes through the hollow portion inside as the injection needle 23 comes out during the period until the injection needle 23 comes out of the puncture hole 16 completely. Finally, a part of the thin-film tube 24 surrounded by the living tissue of the affected part 15 (that is, a part of the thin-film tube 24 that enters the puncture hole 16) becomes hollow. A part of the thin-film tube 24 in the hollow state is easily crushed and deformed by the contraction force of the affected part 15 (state B5). As a result, the puncture hole 16 of the affected part 15 by the injection needle 23 is in a state in which the opening diameter is minimized, and the internal drug solution 7 is not leaked to the outside, that is, is closed.

その後、制御部２９は、上述したように患部１５から注射針２３を抜き取るように駆動部６を制御し始めてから所定の時間が経過後に、この患部１５の穿刺穴１６から薄膜チューブ２４を抜き取るように駆動部２６を制御する。すなわち、制御部２９は、かかる薄膜チューブ２４の一部分が患部１５の収縮力によって十分に圧潰変形したタイミング（患部１５の穿刺穴１６が閉塞状態になったタイミング）に、カプセル型筐体２の内部に薄膜チューブ２４を収納するように駆動部２６を制御する。この場合、駆動部２６は、患部１５の穿刺穴１６から薄膜チューブ２４を抜き取り、カプセル型筐体２の内部に薄膜チューブ２４を収納する（状態Ｂ６）。   Thereafter, the control unit 29 extracts the thin-film tube 24 from the puncture hole 16 of the affected part 15 after a predetermined time has elapsed since the start of controlling the drive unit 6 so as to extract the injection needle 23 from the affected part 15 as described above. The drive unit 26 is controlled. In other words, the control unit 29 detects the inside of the capsule housing 2 at a timing when a part of the thin film tube 24 is sufficiently crushed and deformed by the contraction force of the affected part 15 (a timing when the puncture hole 16 of the affected part 15 is closed). The drive unit 26 is controlled so that the thin film tube 24 is housed in the housing. In this case, the drive unit 26 removes the thin film tube 24 from the puncture hole 16 of the affected part 15 and stores the thin film tube 24 inside the capsule housing 2 (state B6).

ここで、薄膜チューブ２４を抜き取られた患部１５の穿刺穴（穿刺跡）１６は、上述したように閉塞状態である。このため、患部１５は、上述したように注射針２３および薄膜チューブ２４が抜き取られた後であっても、この穿刺穴１６から薬液７を漏出させることなく、内部に薬液７を留める。この結果、患部１５内部の薬液７は、この被検体内部における患部１５以外の体内部位に漏れ広がることがない。   Here, the puncture hole (puncture mark) 16 of the affected part 15 from which the thin film tube 24 has been extracted is in a closed state as described above. For this reason, even after the injection needle 23 and the thin film tube 24 are extracted as described above, the affected part 15 keeps the drug solution 7 inside without leaking the drug solution 7 from the puncture hole 16. As a result, the medicinal solution 7 inside the affected part 15 does not leak and spread in the body part other than the affected part 15 inside the subject.

以上、説明したように、本発明の実施の形態２では、硬質の注射針に摺動可能に薄膜チューブを外嵌し、この薄膜チューブとともに注射針を体内部位に穿刺し、この体内部位の内部に薬液を注入した後、この体内部位の穿刺穴に薄膜チューブを留めた状態を維持しつつ体内部位から注射針を抜き取り、この穿刺穴に留めた薄膜チューブを体内部位の収縮力によって容易に縮小変形させて、この体内部位の穿刺穴を閉塞状態にするようにし、その他を実施の形態１と同様に構成した。このため、上述した実施の形態１と同様の作用効果を享受するとともに、注射針を加熱処理によって縮小変形する必要がなく、これによって、省電力化を促進できるカプセル型医療装置を実現することができる。   As described above, in Embodiment 2 of the present invention, a thin film tube is slidably fitted to a hard injection needle, and the injection needle is punctured into a body part together with the thin film tube. After injecting the drug solution into the puncture hole in the internal body part, the needle is removed from the internal body part while maintaining the state where the thin film tube is retained, and the thin film tube retained in the puncture hole is easily reduced by the contraction force of the internal body part. The puncture hole in this body part was made to be in a closed state by being deformed, and the others were configured in the same manner as in the first embodiment. For this reason, while enjoying the effect similar to Embodiment 1 mentioned above, it is not necessary to shrink-deform an injection needle by heat processing, and, thereby, the capsule type medical device which can promote power saving can be realized. it can.

（実施の形態３）
つぎに、本発明の実施の形態３について説明する。上述した実施の形態１では、体内部位に穿刺した状態の注射針３を加熱処理によって縮小変形させて、この注射針３による体内部位の穿刺穴を閉塞状態にしていたが、この実施の形態３では、体内部位から注射針を抜き取る際の注射針の移動速度を体内部位の収縮速度に比して低速に制御し、これによって、この注射針による体内部位の穿刺穴を閉塞状態にしている。 (Embodiment 3)
Next, a third embodiment of the present invention will be described. In the first embodiment described above, the injection needle 3 that has been punctured into the body part is contracted and deformed by heat treatment so that the puncture hole in the body part by the injection needle 3 is closed. Then, the moving speed of the injection needle when the injection needle is withdrawn from the internal body part is controlled to be lower than the contraction speed of the internal body part, thereby closing the puncture hole of the internal body part by the injection needle.

図１０は、本発明の実施の形態３にかかるカプセル型医療装置の一構成例を示す模式図である。図１０に示すように、この実施の形態３にかかるカプセル型医療装置３１は、上述した実施の形態１にかかるカプセル型医療装置１の注射針３に代えて注射針３３を備え、支持部５に代えて支持部３５を備え、駆動部６に代えて駆動部３６を備え、制御部１３に代えて制御部３９を備える。その他の構成は実施の形態１と同じであり、同一構成部分には同一符号を付している。   FIG. 10 is a schematic diagram illustrating a configuration example of a capsule medical apparatus according to the third embodiment of the present invention. As shown in FIG. 10, the capsule medical device 31 according to the third embodiment includes an injection needle 33 instead of the injection needle 3 of the capsule medical device 1 according to the first embodiment described above, and includes a support unit 5. Instead of this, a support unit 35 is provided, a drive unit 36 is provided instead of the drive unit 6, and a control unit 39 is provided instead of the control unit 13. Other configurations are the same as those of the first embodiment, and the same reference numerals are given to the same components.

注射針３３は、金属等によって形成される硬質の中空針であり、穿刺した体内部位の収縮力によって縮小変形するものではない。また、注射針３３の後端部にはチューブ１０ｂが取り付けられ、注射針３３は、このチューブ１０ｂを介して駆動弁９と連通する。この注射針３３の後端部近傍には支持部３５が取り付けられる。なお、注射針３３は、上述した実施の形態１における注射針３と同様の中空針構造を有する。   The injection needle 33 is a hard hollow needle formed of metal or the like, and does not shrink and deform due to the contraction force of the punctured body part. A tube 10b is attached to the rear end of the injection needle 33, and the injection needle 33 communicates with the drive valve 9 through the tube 10b. A support portion 35 is attached in the vicinity of the rear end portion of the injection needle 33. The injection needle 33 has the same hollow needle structure as the injection needle 3 in the first embodiment described above.

支持部３５は、カプセル型筐体２の開口部２ｃを通して注射針３３が突没可能な態様で注射針３３を支持する。具体的には、支持部３５は、カプセル型筐体２の径方向に対して注射針３３の長手方向が斜めになる態様であり且つ注射針３３の先端開口部が穿刺時に体内部位側を向く態様で注射針３３を支持する。なお、カプセル型筐体２の径方向は、カプセル型筐体２の長手方向の中心軸ＣＬに対して垂直な方向である。また、かかるカプセル型筐体２の径方向に対して注射針３３の長手方向が斜めになる態様は、注射針３３の長手方向がカプセル型筐体２の長手方向および径方向に対して鋭角（すなわち９０度よりも小さい角度）をなす態様である。   The support part 35 supports the injection needle 33 in such a manner that the injection needle 33 can project and retract through the opening 2 c of the capsule housing 2. Specifically, the support part 35 is a mode in which the longitudinal direction of the injection needle 33 is inclined with respect to the radial direction of the capsule housing 2, and the distal end opening of the injection needle 33 faces the body part side at the time of puncturing. In the embodiment, the injection needle 33 is supported. The radial direction of the capsule casing 2 is a direction perpendicular to the central axis CL in the longitudinal direction of the capsule casing 2. Further, the aspect in which the longitudinal direction of the injection needle 33 is oblique with respect to the radial direction of the capsule housing 2 is such that the longitudinal direction of the injection needle 33 is acute with respect to the longitudinal direction and the radial direction of the capsule housing 2 ( That is, the angle is smaller than 90 degrees.

駆動部３６は、カプセル型筐体２から注射針３３を突没させて、被検体の体内部位に注射針３３を穿刺し、この穿刺した注射針３３を体内部位から抜き取ってカプセル型筐体２の内部に収納する針駆動手段として機能する。具体的には、駆動部３６は、リニアアクチュエータ等を用いて実現され、注射針３３の支持部３５と接続される。駆動部３６は、支持部３５を介して注射針３３を所定の斜め方向（図１０に示す太線矢印方向）に往復動作させる。かかる駆動部３６は、開口部２ｃからカプセル型筐体２の外部に注射針３３を突き出し、所定の移動速度で被検体の体内部位に注射針３３を穿刺する。その後、駆動部３６は、制御部３９の制御に基づく動作タイミングに、この体内部位の収縮速度に比して低速の移動速度で体内部位から注射針３３を抜き取り、カプセル型筐体２内部に注射針３３を収納する。   The drive unit 36 protrudes and retracts the injection needle 33 from the capsule housing 2 to puncture the injection needle 33 into the body part of the subject, and removes the punctured injection needle 33 from the body part to obtain the capsule housing 2. It functions as a needle drive means that is housed inside the. Specifically, the drive unit 36 is realized using a linear actuator or the like, and is connected to the support unit 35 of the injection needle 33. The drive unit 36 causes the injection needle 33 to reciprocate in a predetermined oblique direction (the direction of the thick arrow shown in FIG. 10) via the support unit 35. The drive unit 36 protrudes the injection needle 33 from the opening 2c to the outside of the capsule housing 2 and punctures the injection needle 33 into the body part of the subject at a predetermined moving speed. Thereafter, the drive unit 36 removes the injection needle 33 from the body part at an operation timing based on the control of the control unit 39 at a moving speed that is lower than the contraction speed of the body part, and injects it into the capsule housing 2. The needle 33 is stored.

制御部３９は、駆動部３６の動作速度を制御して、体内部位に注射針３３を穿刺する際の注射針３３の移動速度（穿刺速度）と体内部位から注射針３３を抜き取る際の注射針３３の移動速度（抜取速度）とを制御する。具体的には、制御部３９は、カプセル型筐体２から突き出した注射針３３を所定の穿刺速度で体内部位に穿刺するように駆動部３６を制御する。また、制御部３９は、この体内部位の収縮速度に比して低速の抜取速度で体内部位から注射針３３を抜き取るように駆動部３６を制御する。ここで、かかる制御部３９によって制御される注射針３３の抜取速度は、注射針３３を介して薬液７を注入された体内部位の収縮力に比して低速であれば、注射針３３の穿刺速度に比して高速であってもよいし、低速であってもよいし、注射針３３の穿刺速度と同じであってもよい。なお、制御部３９は、かかる駆動部３６の動作速度の制御（すなわち注射針３３の穿刺速度および抜取速度の制御）以外、上述した実施の形態１にかかるカプセル型医療装置１の制御部１３と同様の機能を有する。   The control unit 39 controls the operation speed of the driving unit 36 to move the injection needle 33 when the injection needle 33 is punctured into the body part (puncture speed) and the injection needle when the injection needle 33 is extracted from the body part. 33 moving speed (sampling speed) is controlled. Specifically, the control unit 39 controls the driving unit 36 so that the injection needle 33 protruding from the capsule housing 2 is punctured into the body part at a predetermined puncture speed. Further, the control unit 39 controls the drive unit 36 so as to extract the injection needle 33 from the internal region at a lower extraction speed than the contraction speed of the internal region. Here, if the extraction speed of the injection needle 33 controlled by the control unit 39 is lower than the contraction force of the body part into which the drug solution 7 has been injected through the injection needle 33, the puncture of the injection needle 33 is performed. The speed may be higher than the speed, may be lower, or may be the same as the puncture speed of the injection needle 33. The control unit 39, except for the control of the operation speed of the drive unit 36 (that is, the control of the puncture speed and extraction speed of the injection needle 33), is the same as the control unit 13 of the capsule medical device 1 according to the first embodiment described above. It has the same function.

つぎに、体内部位に向けて注射針３３を突き出してから、注射完了後の体内部位から注射針３３を抜き取ってカプセル型筐体２の内部に注射針３３を収納するまでのカプセル型医療装置３１の一連の動作を説明する。図１１は、本発明の実施の形態３にかかるカプセル型医療装置が体内部位に注射する際の一連の処理手順を例示するフローチャートである。なお、この実施の形態３にかかるカプセル型医療装置３１は、上述した実施の形態１にかかるカプセル型医療装置１の場合と同様に、被検体内部における患部等の所望の体内部位に到達して注射針３３と所望の体内部位との位置を合わせる。   Next, the capsule medical device 31 from when the injection needle 33 is protruded toward the internal body part until the injection needle 33 is extracted from the internal body part after completion of the injection and the injection needle 33 is accommodated inside the capsule housing 2. A series of operations will be described. FIG. 11 is a flowchart illustrating a series of processing procedures when the capsule medical device according to the third embodiment of the present invention injects into a body part. Note that the capsule medical device 31 according to the third embodiment reaches a desired in-vivo site such as an affected part in the subject, similarly to the capsule medical device 1 according to the first embodiment described above. The positions of the injection needle 33 and the desired internal part are aligned.

被検体内部における患部等の所望の体内部位に到達したカプセル型医療装置３１において、制御部３９は、図１１に示すように、上述した外部装置からの制御信号に基づいて、まず、所定の穿刺速度でカプセル型筐体２から注射針３３を突き出すように駆動部３６を制御する（ステップＳ１０１）。この場合、駆動部３６は、制御部３９の制御に基づいてカプセル型筐体２から注射針３３を突出させ、制御部３９によって制御される穿刺速度で体内部位に注射針３３を穿刺する。かかる注射針３３は、体内部位側に先端開口部を向けた態様で体内部位に突き刺さる。   In the capsule medical device 31 that has reached a desired internal site such as an affected part in the subject, the control unit 39 first performs predetermined puncture based on the control signal from the external device described above, as shown in FIG. The drive unit 36 is controlled so as to protrude the injection needle 33 from the capsule housing 2 at a speed (step S101). In this case, the drive unit 36 causes the injection needle 33 to protrude from the capsule housing 2 based on the control of the control unit 39 and punctures the injection needle 33 into the body part at a puncture speed controlled by the control unit 39. The injection needle 33 is pierced into the body part in such a manner that the tip opening is directed to the body part side.

つぎに、制御部３９は、この体内部位に注射針３３を穿刺した状態を維持しつつ、駆動弁９に開駆動を行わせる（ステップＳ１０２）。この場合、駆動弁９は、連通管１０ａおよびチューブ１０ｂを介して吐出バルーン８と注射針３３とを連通状態にする。吐出バルーン８は、この注射針３３を介して体内部位に薬液７を注入する。かかる薬液７は、上述した実施の形態１の場合と同様に、この体内部位の内部を伸展しつつ、この体内部位の内部に注入される。   Next, the control unit 39 causes the drive valve 9 to perform the opening drive while maintaining the state where the injection needle 33 is punctured into the body part (step S102). In this case, the drive valve 9 brings the discharge balloon 8 and the injection needle 33 into communication with each other via the communication tube 10a and the tube 10b. The discharge balloon 8 injects the drug solution 7 into the body part through the injection needle 33. Similar to the case of the first embodiment, the medicinal solution 7 is injected into the internal body part while extending the internal part.

その後、制御部３９は、この体内部位に注射針３３を穿刺した状態を維持しつつ、この注射針３３を介して体内部位に薬液７を注入し始めてから（すなわち駆動弁９に開駆動を行わせてから）所定の時間が経過したか否かを判断する（ステップＳ１０３）。制御部３９は、薬液７を注入し始めてから所定の時間が未だ経過していないと判断した場合（ステップＳ１０３，Ｎｏ）、このステップＳ１０３を繰り返す。この場合、吐出バルーン８は、注射針３３を介して体内部位の内部に薬液７を注入し続ける。   After that, the control unit 39 maintains the state where the injection needle 33 is punctured into the body part, and starts to inject the drug solution 7 into the body part via the injection needle 33 (that is, opens the drive valve 9). It is determined whether or not a predetermined time has elapsed (step S103). When it is determined that the predetermined time has not yet elapsed since the start of the injection of the chemical solution 7 (No at Step S103), the control unit 39 repeats Step S103. In this case, the discharge balloon 8 continues to inject the drug solution 7 into the body part via the injection needle 33.

一方、制御部３９は、薬液７を注入し始めてから所定の時間が経過したと判断した場合（ステップＳ１０３，Ｙｅｓ）、駆動弁９に閉駆動を行わせる（ステップＳ１０４）。この場合、駆動弁９は、上述した吐出バルーン８と注射針３３との連通状態を遮断する。吐出バルーン８は、このように駆動弁９によって注射針３３との連通状態を遮断されるまでに、この体内部位の内部に必要量の薬液７を注入し終える。   On the other hand, when the control unit 39 determines that a predetermined time has elapsed since the start of the injection of the chemical solution 7 (Yes in Step S103), the control unit 39 causes the drive valve 9 to perform a closing drive (Step S104). In this case, the drive valve 9 blocks the communication state between the discharge balloon 8 and the injection needle 33 described above. The discharge balloon 8 finishes injecting a required amount of the drug solution 7 into the internal region until the communication state with the injection needle 33 is blocked by the drive valve 9 in this way.

このように吐出バルーン８が薬液７の注入動作を終了した状態において、制御部３９は、この注射済みの体内部位から注射針３３を低速抜去するように駆動部３６を制御する（ステップＳ１０５）。この場合、制御部３９は、この注射済みの体内部位の収縮速度に比して低速の抜取速度で注射針３３を抜き取るように駆動部３６を制御する。駆動部３６は、かかる低速の抜取速度で注射針３３を移動させることによって、この注射済みの体内部位から注射針３３を完全に抜き取るまでの期間、この注射針３３による体内部位の穿刺穴を体内部位自身（すなわち生体組織）の収縮力によって閉塞状態にするために必要な時間を確保する。かかる駆動部３６は、この注射済みの体内部位の穿刺穴を生体組織の収縮力によって徐々に閉塞状態にしつつ、この穿刺穴から注射針３３を抜き取る。なお、このように駆動部３６を制御する制御部３９は、注射針３３による体内部位の穿刺穴を閉塞状態にする閉塞手段として機能する。   In the state where the discharge balloon 8 has finished the injection operation of the drug solution 7 as described above, the control unit 39 controls the drive unit 36 so as to remove the injection needle 33 at a low speed from the injected body part (step S105). In this case, the control unit 39 controls the drive unit 36 so as to extract the injection needle 33 at a lower extraction speed than the contraction speed of the injected internal body part. The drive unit 36 moves the injection needle 33 at such a low extraction speed, so that the puncture hole in the internal region by the injection needle 33 is inserted into the internal body during a period until the injection needle 33 is completely extracted from the injected internal region. The time required for making it occluded by the contraction force of the site itself (ie, living tissue) is secured. The drive unit 36 removes the injection needle 33 from the puncture hole while gradually closing the puncture hole in the injected body part by the contraction force of the living tissue. In addition, the control unit 39 that controls the drive unit 36 in this manner functions as a closing unit that closes the puncture hole in the body part by the injection needle 33.

その後、制御部３９は、この注射済みの体内部位から抜き取った注射針３３をカプセル型筐体２の内部に収納するように駆動部３６を制御し（ステップＳ１０６）、この一連の動作（一連の処理手順）を終了する。この場合、駆動部３６は、制御部３９によって制御された移動速度でカプセル型筐体２の内部に注射針３３を収納する。なお、かかる注射針３３の収納時の移動速度は、上述した穿刺速度または抜取速度と同じ速度であってもよいし、異なる速度であってもよい。   Thereafter, the control unit 39 controls the drive unit 36 so as to store the injection needle 33 extracted from the injected body part in the capsule housing 2 (step S106). The processing procedure) is terminated. In this case, the drive unit 36 stores the injection needle 33 inside the capsule housing 2 at a moving speed controlled by the control unit 39. The moving speed when the injection needle 33 is stored may be the same speed as the puncture speed or extraction speed described above, or may be a different speed.

つぎに、被検体内部における所望の体内部位として被検体内部の患部を例示して、カプセル型医療装置３１が上述したステップＳ１０４の動作を行って患部の穿刺穴に及ぼす作用について具体的に説明する。図１２は、低速の抜取速度で患部から注射針を抜き取りつつ穿刺穴を閉塞する状態を示す模式図である。   Next, the affected part inside the subject is illustrated as a desired internal part inside the subject, and the action of the capsule medical device 31 on the puncture hole of the affected part by performing the operation of step S104 described above will be specifically described. . FIG. 12 is a schematic diagram showing a state in which the puncture hole is closed while the injection needle is extracted from the affected area at a low extraction speed.

図１２に示すように、患部１５の内部に薬液７を注入後の注射針３３は、上述した駆動部３６の作用によって、この患部１５の収縮時間に比して低速の抜取速度で患部１５の外部に向けて徐々に移動する。この場合、注射針３３は、患部１５の穿刺穴１６を患部１５自身（すなわち生体組織）の収縮力によって閉塞状態にするために必要な時間を費やして、この穿刺穴１６から完全に抜け出る。患部１５は、かかる注射針３３の移動に伴って穿刺穴１６の開口径を徐々に縮小し、穿刺穴１６から注射針３３が完全に抜け出た際に穿刺穴１６を閉塞状態にする。   As shown in FIG. 12, the injection needle 33 after injecting the medicinal solution 7 into the affected area 15 is removed from the affected area 15 at a lower extraction speed than the contracted time of the affected area 15 by the action of the drive unit 36 described above. Move gradually towards the outside. In this case, the injection needle 33 is completely removed from the puncture hole 16 by spending a time necessary for making the puncture hole 16 of the affected area 15 occluded by the contraction force of the affected area 15 itself (ie, living tissue). The affected part 15 gradually reduces the opening diameter of the puncture hole 16 with the movement of the injection needle 33, and closes the puncture hole 16 when the injection needle 33 is completely removed from the puncture hole 16.

ここで、このように低速の抜取速度で注射針３３を抜き取られた患部１５は、上述したように穿刺穴１６を閉塞状態にしているため、穿刺穴１６から注射針３３を完全に抜き取られた後であっても、この穿刺穴１６から薬液７を漏出させることなく、内部に薬液７を留める。この結果、患部１５内部の薬液７は、この被検体内部における患部１５以外の体内部位に漏れ広がることがない。   Here, since the affected part 15 from which the injection needle 33 has been extracted at such a low extraction speed has the puncture hole 16 closed as described above, the injection needle 33 has been completely extracted from the puncture hole 16. Even after, the drug solution 7 is retained inside without causing the drug solution 7 to leak from the puncture hole 16. As a result, the medicinal solution 7 inside the affected part 15 does not leak and spread in the body part other than the affected part 15 inside the subject.

以上、説明したように、本発明の実施の形態３では、制御部が、体内部位の収縮速度に比して低速の抜取速度で穿刺穴から注射針を抜き取るように駆動部を制御して、この穿刺穴を閉塞状態にするようにし、その他を実施の形態１と略同様に構成した。このため、注射済みの体内部位から注射針を完全に抜き取るまでの期間に、この注射針による体内部位の穿刺穴を生体組織の収縮力によって閉塞状態にするために必要な時間を確保でき、これによって、上述した実施の形態１の場合と同様の作用効果を享受するとともに、部品点数を低減して、組立し易さの向上および組立コストの低減を促進できるカプセル型医療装置を実現することができる。   As described above, in the third embodiment of the present invention, the control unit controls the drive unit so as to extract the injection needle from the puncture hole at a lower extraction speed than the contraction speed of the body part, The puncture hole was closed, and the others were configured in substantially the same manner as in the first embodiment. For this reason, it is possible to secure the time necessary for the puncture hole of the internal part by the injection needle to be closed by the contraction force of the living tissue during the period until the injection needle is completely removed from the injected internal part. Thus, it is possible to realize a capsule medical device that can enjoy the same operational effects as in the case of the first embodiment described above, reduce the number of parts, and promote the improvement in ease of assembly and the reduction in assembly cost. it can.

また、カプセル型筐体の径方向に対して注射針の長手方向が斜めになる態様でカプセル型筐体から注射針を突出させているので、被検体の体内部位の表面（臓器内壁面）に対して鋭角をなした態様で体内部位に注射針を穿刺することができる。これによって、注射針による体内部位の穿刺穴の長さを、体内部位に対して垂直に注射針を穿刺した場合に比して長くすることができ、この結果、穿刺穴からの薬液漏出の防止効果を一層高めることができる。   In addition, since the injection needle protrudes from the capsule-type housing in such a manner that the longitudinal direction of the injection needle is oblique with respect to the radial direction of the capsule-type housing, the surface of the body part of the subject (the internal wall of the organ) On the other hand, the injection needle can be punctured into the body part in a form with an acute angle. As a result, the length of the puncture hole in the body part by the injection needle can be made longer than the case where the injection needle is punctured perpendicularly to the body part, and as a result, prevention of leakage of the drug solution from the puncture hole can be achieved. The effect can be further enhanced.

さらに、穿刺対象である体内部位側に注射針の先端開口部を向けた態様で体内部位に注射針を穿刺するので、体内部位に穿刺した注射針の先端開口部（針穴）を目的の生体組織層側に容易に向けることができ、これによって、この目的の生体組織層に薬液を容易に注入することができる。   Further, since the injection needle is punctured in the body part in such a manner that the tip opening part of the injection needle faces the body part side to be punctured, the tip opening part (needle hole) of the syringe needle punctured in the body part is used as the target living body. It can be easily directed to the tissue layer side, whereby the drug solution can be easily injected into the target biological tissue layer.

（実施の形態３の変形例１）
つぎに、本発明の実施の形態３の変形例１について説明する。上述した実施の形態３では、穿刺対象の体内部位側に注射針３３の先端開口部を向けた態様でカプセル型筐体２から注射針３３を突没させていたが、この実施の形態３の変形例１では、体内部位に注射針３３を穿刺する場合、この注射針３３の先端開口部を体内部位側に向け、体内部位から注射針３３を抜き取る場合、この注射針３３の先端開口部の方向を反転させている。 (Modification 1 of Embodiment 3)
Next, Modification 1 of Embodiment 3 of the present invention will be described. In the above-described third embodiment, the injection needle 33 protrudes from the capsule housing 2 in such a manner that the distal end opening of the injection needle 33 faces the body part side of the puncture target. In the first modification, when the injection needle 33 is punctured into the body part, the tip opening portion of the injection needle 33 is directed toward the body part side, and when the injection needle 33 is removed from the body part, the tip opening part of the injection needle 33 is The direction is reversed.

図１３は、本発明の実施の形態３の変形例１にかかるカプセル型医療装置の一構成例を示す模式図である。図１３に示すように、この実施の形態３の変形例１にかかるカプセル型医療装置４１は、上述した実施の形態３にかかるカプセル型医療装置３１の制御部３９に代えて制御部４９を備え、注射針３３をその長手軸を中心に回転する回転駆動部４６をさらに備える。その他の構成は実施の形態３と同じであり、同一構成部分には同一符号を付している。   FIG. 13 is a schematic diagram illustrating a configuration example of a capsule medical apparatus according to the first modification of the third embodiment of the present invention. As illustrated in FIG. 13, a capsule medical device 41 according to the first modification of the third embodiment includes a control unit 49 instead of the control unit 39 of the capsule medical device 31 according to the third embodiment described above. The rotation needle 46 further rotates the injection needle 33 about its longitudinal axis. Other configurations are the same as those of the third embodiment, and the same components are denoted by the same reference numerals.

回転駆動部４６は、回転アクチュエータ等を用いて実現され、例えば注射針３３の後端部近傍と接続される。回転駆動部４６は、制御部４９の制御に基づいて、注射針３３の長手軸回りに注射針３３を回転する。かかる回転駆動部４６は、体内部位に注射針３３を穿刺する際の注射針３３の先端開口部の向きと、穿刺状態の注射針３３を体内部位から抜き取る際の注射針３３の先端開口部の向きとを決定する。   The rotation drive unit 46 is realized using a rotary actuator or the like, and is connected to, for example, the vicinity of the rear end portion of the injection needle 33. The rotation drive unit 46 rotates the injection needle 33 around the longitudinal axis of the injection needle 33 based on the control of the control unit 49. The rotation drive unit 46 is provided for the direction of the distal end opening of the injection needle 33 when the injection needle 33 is punctured into the body part, and the direction of the distal end opening of the injection needle 33 when the punctured injection needle 33 is removed from the body part. Determine the orientation.

制御部４９は、回転駆動部４６の駆動を制御して、体内部位に注射針３３を穿刺する際の注射針３３の先端開口部の向きと、穿刺状態の注射針３３を体内部位から抜き取る際の注射針３３の先端開口部の向きとを制御する。具体的には、制御部４９は、体内部位に注射針３３を穿刺する際、この注射針３３の先端開口部が体内部位側を向くように回転駆動部４６を制御し、体内部位に穿刺した状態の注射針３３をこの体内部位から抜き取る際、この注射針３３の先端開口部の方向が反転する態様に注射針３３を回転するように回転駆動部４６を制御する。ここで、この注射針３３の先端開口部の方向が反転する態様とは、体内部位に注射針３３を穿刺する際の注射針３３の先端開口部の方向と反対の方向を向く態様であり、具体的には、注射針３３の先端開口部が体内部位の内部側（注入薬液側）からカプセル型筐体２側（穿刺部位の外部側）の方向を向く態様である。なお、制御部４９は、かかる回転駆動部４６の制御以外、上述した実施の形態３にかかるカプセル型医療装置３１の制御部３９と同様の機能を有する。   The control unit 49 controls the drive of the rotation driving unit 46 to remove the direction of the distal end opening of the injection needle 33 when the injection needle 33 is punctured into the body part and when the injection needle 33 in the puncture state is extracted from the body part. The direction of the tip opening of the injection needle 33 is controlled. Specifically, when puncturing the injection needle 33 in the body part, the control unit 49 controls the rotation drive unit 46 so that the distal end opening of the injection needle 33 faces the body part side, and punctures the body part. When the injection needle 33 in the state is extracted from the body part, the rotation drive unit 46 is controlled so as to rotate the injection needle 33 so that the direction of the distal end opening of the injection needle 33 is reversed. Here, the aspect in which the direction of the distal end opening of the injection needle 33 is reversed is an aspect in which the direction toward the direction opposite to the direction of the distal end opening of the injection needle 33 when the injection needle 33 is punctured into a body part, Specifically, the distal end opening of the injection needle 33 is directed from the inner side of the body part (injected drug solution side) to the capsule housing 2 side (outside of the puncture part). The control unit 49 has the same functions as the control unit 39 of the capsule medical device 31 according to the third embodiment described above, except for the control of the rotation driving unit 46.

つぎに、体内部位に向けて注射針３３を突き出してから、注射完了後の体内部位から注射針３３を抜き取ってカプセル型筐体２の内部に注射針３３を収納するまでのカプセル型医療装置４１の一連の動作を説明する。図１４は、本発明の実施の形態３の変形例１にかかるカプセル型医療装置が体内部位に注射する際の一連の処理手順を例示するフローチャートである。なお、この実施の形態３の変形例１にかかるカプセル型医療装置４１は、上述した実施の形態３にかかるカプセル型医療装置３１の場合と同様に、被検体内部における患部等の所望の体内部位に到達して注射針３３と所望の体内部位との位置を合わせる。   Next, the capsule medical device 41 from when the injection needle 33 is protruded toward the internal body part until the injection needle 33 is extracted from the internal body part after the injection is completed and the injection needle 33 is accommodated inside the capsule housing 2. A series of operations will be described. FIG. 14 is a flowchart illustrating a series of processing procedures when the capsule medical device according to the first modification of the third embodiment of the present invention injects into a body part. The capsule medical device 41 according to the first modification of the third embodiment is similar to the capsule medical device 31 according to the third embodiment described above in a desired internal region such as an affected part in the subject. And the positions of the injection needle 33 and the desired body part are aligned.

被検体内部における患部等の所望の体内部位に到達したカプセル型医療装置４１において、制御部４９は、図１４に示すように、上述した外部装置からの制御信号に基づいて、まず、注射針３３の先端開口部が体内部位側を向くように回転駆動部４６を制御しつつ、所定の穿刺速度でカプセル型筐体２から注射針３３を突き出すように駆動部３６を制御する（ステップＳ２０１）。このステップＳ２０１において、回転駆動部４６は、注射針３３の先端開口部を穿刺対象の体内部位側に向ける。ここで、制御部４９は、回転駆動部４６の回転状態をもとに注射針３３の先端開口部の方向を把握し、注射針３３の先端開口部が穿刺対象の体内部位側を向いていない場合、この体内部位側に注射針３３の先端開口部を向ける態様に注射針３３を回転するように回転駆動部４６を制御する。一方、制御部４９は、注射針３３の先端開口部が穿刺対象の体内部位側を向いている場合、この注射針３３の状態を維持するように回転駆動部４６を制御する。   In the capsule medical device 41 that has reached a desired internal site such as an affected part in the subject, as shown in FIG. 14, the control unit 49 first starts the injection needle 33 based on the control signal from the external device described above. The drive unit 36 is controlled so as to protrude the injection needle 33 from the capsule-type housing 2 at a predetermined puncture speed while controlling the rotation drive unit 46 so that the distal end opening portion faces the body part side (step S201). In step S201, the rotation driving unit 46 directs the distal end opening of the injection needle 33 toward the body part side of the puncture target. Here, the control part 49 grasps | ascertains the direction of the front-end | tip opening part of the injection needle 33 based on the rotation state of the rotation drive part 46, and the front-end | tip opening part of the injection needle 33 does not face the body part side of the puncture object. In this case, the rotation drive unit 46 is controlled so as to rotate the injection needle 33 so that the distal end opening of the injection needle 33 faces the body part side. On the other hand, the control part 49 controls the rotation drive part 46 so that the state of this injection needle 33 may be maintained, when the front-end | tip opening part of the injection needle 33 has faced the body region side of puncture object.

なお、このステップＳ２０１において、駆動部３６は、上述した実施の形態３の場合と同様に、制御部４９の制御に基づいてカプセル型筐体２から注射針３３を突出させ、制御部４９によって制御される穿刺速度で体内部位に注射針３３を穿刺する。かかる注射針３３は、体内部位側に先端開口部を向けた態様で体内部位に突き刺さる。   In this step S201, the drive unit 36 causes the injection needle 33 to protrude from the capsule-type casing 2 based on the control of the control unit 49, and is controlled by the control unit 49, as in the case of the third embodiment described above. The injection needle 33 is punctured into the body part at the puncturing speed. The injection needle 33 is pierced into the body part in such a manner that the tip opening is directed to the body part side.

つぎに、制御部４９は、図１１に示したステップＳ１０２と同様に、この体内部位に注射針３３を穿刺した状態を維持しつつ、駆動弁９に開駆動を行わせ（ステップＳ２０２）、その後、図１１に示したステップＳ１０３と同様に、この注射針３３の穿刺状態を維持しつつ、駆動弁９に開駆動を行わせてから所定の時間が経過したか否かを判断する（ステップＳ２０３）。制御部４９は、ステップＳ２０３において所定の時間が経過していない場合（ステップＳ２０３，Ｎｏ）、このステップＳ２０３を繰り返す。一方、制御部４９は、ステップＳ２０３において所定の時間が経過した場合（ステップＳ２０３，Ｙｅｓ）、図１１に示したステップＳ１０４と同様に、駆動弁９に閉駆動を行わせる（ステップＳ２０４）。   Next, similarly to step S102 shown in FIG. 11, the control unit 49 causes the drive valve 9 to perform the opening drive while maintaining the state where the injection needle 33 is punctured into the body part (step S202), and thereafter Similarly to step S103 shown in FIG. 11, while maintaining the puncture state of the injection needle 33, it is determined whether or not a predetermined time has elapsed since the drive valve 9 was opened (step S203). ). If the predetermined time has not elapsed in step S203 (step S203, No), the control unit 49 repeats step S203. On the other hand, when a predetermined time has elapsed in step S203 (step S203, Yes), the control unit 49 causes the drive valve 9 to perform a closed drive, similarly to step S104 shown in FIG. 11 (step S204).

このように駆動部９に閉駆動を行わせた状態（すなわち吐出バルーン８が薬液７の注入動作を終了した状態）において、制御部４９は、注射針３３の開口方向を反転するように回転駆動部４６を制御する（ステップＳ２０５）。このステップＳ２０５において、制御部４９は、体内部位に注射針３３を穿刺する際の状態から注射針３３の先端開口部の方向が反転するように回転駆動部４６を制御する。回転駆動部４６は、体内部位に穿刺状態の注射針３３をその長手軸回りに回転して、この穿刺状態の注射針３３の先端開口部を、この体内部位の内部側（注入薬液側）からカプセル型筐体２側（穿刺部位の外部側）の方向に向ける。   In the state in which the drive unit 9 is thus closed (that is, the discharge balloon 8 has finished the injection operation of the drug solution 7), the control unit 49 is rotationally driven so as to reverse the opening direction of the injection needle 33. The unit 46 is controlled (step S205). In step S205, the control unit 49 controls the rotation driving unit 46 so that the direction of the distal end opening of the injection needle 33 is reversed from the state when the injection needle 33 is punctured into a body part. The rotation drive part 46 rotates the injection needle 33 in the puncture state around the longitudinal axis of the puncture state of the injection needle 33 around the longitudinal axis of the injection needle 33 in the puncture state from the internal side (infusion drug solution side) of the internal part. The direction is toward the capsule housing 2 side (outside the puncture site).

つぎに、制御部４９は、かかる注射針３３の先端開口部の方向を回転駆動部４６に維持させつつ、図１１に示したステップＳ１０５と同様に、この注射済みの体内部位から注射針３３を低速抜去するように駆動部３６を制御し（ステップＳ２０６）、これによって、この注射針３３による体内部位の穿刺穴を体内部位自身（すなわち生体組織）の収縮力によって閉塞状態にするために必要な時間を確保する。   Next, the control unit 49 maintains the direction of the distal end opening of the injection needle 33 in the rotation drive unit 46, and in the same manner as in step S105 shown in FIG. The drive unit 36 is controlled so as to be removed at a low speed (step S206), and this is necessary to make the puncture hole in the body part by the injection needle 33 occluded by the contraction force of the body part itself (ie, living tissue). Reserve time.

その後、制御部４９は、図１１に示したステップＳ１０６と同様に、この注射針３３をカプセル型筐体２の内部に収納するように駆動部３６を制御し（ステップＳ２０７）、この一連の動作（一連の処理手順）を終了する。   Thereafter, the control unit 49 controls the drive unit 36 so as to store the injection needle 33 in the capsule housing 2 (step S207), similarly to step S106 shown in FIG. The (series of processing procedures) is terminated.

なお、上述したステップＳ２０５，Ｓ２０６において、制御部４９は、穿刺状態の注射針３３の先端開口部の方向を反転させつつ、上述した低速の抜取速度で体内部位から注射針３３を抜き取るように、回転駆動部４６および駆動部３６を制御してもよい。すなわち、回転駆動部４６は、体内部位の穿刺穴から注射針３３の先端開口部を露出する際に注射針３３の先端開口部をカプセル型筐体２側に向けていれば、この穿刺穴内部において注射針３３の先端開口部を如何なる方向に向けていてもよい。   In steps S205 and S206 described above, the control unit 49 reverses the direction of the distal end opening of the injection needle 33 in the puncture state, and extracts the injection needle 33 from the body part at the low extraction speed described above. The rotation drive unit 46 and the drive unit 36 may be controlled. That is, if the rotation drive unit 46 exposes the distal end opening of the injection needle 33 from the puncture hole in the body part, the rotation drive unit 46 has an inside of the puncture hole. The tip opening of the injection needle 33 may be oriented in any direction.

つぎに、被検体内部における所望の体内部位として被検体内部の患部を例示して、カプセル型医療装置４１が上述したステップＳ２０５，Ｓ２０６の動作を行って患部の穿刺穴に及ぼす作用について具体的に説明する。図１５は、カプセル型筐体側に先端開口部を向けた状態の注射針を低速の抜取速度で患部から抜き取りつつ穿刺穴を閉塞する状態を示す模式図である。なお、図１５に示す注射針３３の穿刺時の状態は、上述した実施の形態３の場合と同様である。   Next, the affected part inside the subject is illustrated as a desired internal part inside the subject, and the action of the capsule medical device 41 on the puncture hole of the affected part by performing the operations of steps S205 and S206 described above is specifically described. explain. FIG. 15 is a schematic diagram showing a state in which the puncture hole is closed while the injection needle with the tip opening directed toward the capsule housing is withdrawn from the affected area at a low extraction speed. In addition, the state at the time of puncture of the injection needle 33 shown in FIG. 15 is the same as that of the case of Embodiment 3 mentioned above.

図１５に示すように、患部１５の内部に薬液７を注入後の注射針３３は、上述した回転駆動部４６の作用によって、先端開口部の方向を穿刺時の状態から反転させて患部１５の外部側（上述したカプセル型筐体２側）に先端開口部を向ける。かかる状態の注射針３３は、上述した駆動部３６の作用によって、この患部１５の収縮時間に比して低速の抜取速度で患部１５の外部に向けて徐々に移動する。   As shown in FIG. 15, the injection needle 33 after injecting the medicinal solution 7 into the affected part 15 reverses the direction of the distal end opening from the state at the time of puncture by the action of the rotation drive part 46 described above. The front end opening is directed to the outside (the capsule casing 2 side described above). The injection needle 33 in such a state is gradually moved toward the outside of the affected area 15 at a sampling speed that is lower than the contraction time of the affected area 15 by the action of the drive unit 36 described above.

ここで、注射針３３は、上述した実施の形態３の場合と同様に、被検体の体内部位の表面（臓器内壁面）に対して鋭角をなした態様（すなわち斜めの態様）で体内部位に穿刺する。かかる注射針３３は、患部１５の穿刺穴１６から抜け出る際、図１５に示す抜去時の状態のように患部１５の外部側に先端開口部を向けることによって、この穿刺穴１６から先端開口部をより早期に露出する。すなわち、上述した駆動部３６は、このように患部１５の外部側に先端開口部を向けた状態の注射針３３を穿刺穴１６から抜き取ることによって、この穿刺穴１６の内部に残る注射針３３の残留部分の外径寸法をより早期に縮小することができる。この結果、患部１５は、注射針３３の先端開口部が患部１５の内部側を向く場合に比して早期且つ容易に、患部１５自身の収縮力によって穿刺穴１６の開口径を縮小して穿刺穴１６を閉塞状態にする。   Here, as in the case of the third embodiment described above, the injection needle 33 is placed on the body part in an aspect (that is, an oblique aspect) that forms an acute angle with respect to the surface of the body part of the subject (the inner wall surface of the organ). Puncture. When the injection needle 33 exits from the puncture hole 16 of the affected area 15, the distal end opening is directed from the puncture hole 16 by directing the distal end opening to the outside of the affected area 15 as shown in FIG. It is exposed earlier. That is, the drive unit 36 described above removes the injection needle 33 with the distal end opening facing the outside of the affected part 15 from the puncture hole 16, so that the injection needle 33 remaining inside the puncture hole 16 is removed. The outer diameter of the remaining portion can be reduced earlier. As a result, the affected area 15 is punctured by reducing the opening diameter of the puncture hole 16 by the contraction force of the affected area 15 earlier and more easily than when the distal end opening of the injection needle 33 faces the inside of the affected area 15. The hole 16 is closed.

このように穿刺穴１６を閉塞状態にした患部１５は、穿刺穴１６から注射針３３を完全に抜き取られた後であっても、この穿刺穴１６から薬液７を漏出させることなく、内部に薬液７を留める。この結果、患部１５内部の薬液７は、この被検体内部における患部１５以外の体内部位に漏れ広がることがない。   Thus, even if the affected part 15 which made the puncture hole 16 obstruct | occluded after the injection needle 33 was completely extracted from the puncture hole 16, it does not leak the chemical | medical solution 7 from this puncture hole 16, but a chemical | medical solution inside Fasten 7 As a result, the medicinal solution 7 inside the affected part 15 does not leak and spread in the body part other than the affected part 15 inside the subject.

以上、説明したように、本発明の実施の形態３の変形例１では、回転駆動部によって注射針をその長手軸回りに回転することによって、体内部位から注射針を抜き取る際の注射針の先端開口部を穿刺部位の外部側（カプセル型筐体側）に向けるようにし、その他を実施の形態３と同様に構成した。このため、上述した実施の形態３の場合と同様の作用効果を享受するとともに、体内部位から注射針を抜き取る際、この体内部位の穿刺穴の内部に残る注射針の残留部分の外径寸法をより早期に縮小でき、これによって、この体内部位の穿刺穴をより早期且つ容易に閉塞状態にすることが可能なカプセル型医療装置を実現できる。   As described above, in the first modification of the third embodiment of the present invention, the tip of the injection needle when the injection needle is extracted from the body part by rotating the injection needle around its longitudinal axis by the rotation drive unit. The opening was directed to the outside of the puncture site (capsule-type housing side), and the others were configured in the same manner as in the third embodiment. For this reason, while enjoying the same operation effect as the case of Embodiment 3 mentioned above, when extracting an injection needle from an internal part, the outside diameter size of the remaining part of the injection needle which remains inside the puncture hole of this internal part is set. It is possible to reduce the capsule size earlier, thereby realizing a capsule medical device capable of closing the puncture hole in the body part earlier and easily.

（実施の形態４）
つぎに、本発明の実施の形態４について説明する。上述した実施の形態１では、体内部位に穿刺した状態の注射針３を加熱処理によって縮小変形させて、この注射針３による体内部位の穿刺穴を閉塞状態にしていたが、この実施の形態４では、注射針を穿刺した体内部位の生体組織を焼灼することによって、この体内部位の穿刺穴を閉塞状態にしている。 (Embodiment 4)
Next, a fourth embodiment of the present invention will be described. In the first embodiment described above, the injection needle 3 that has been punctured into the body part is reduced and deformed by heat treatment, and the puncture hole in the body part by the injection needle 3 is closed, but this embodiment 4 Then, the puncture hole of this internal body part is made into the obstruct | occluded state by cauterizing the biological tissue of the internal body part punctured with the injection needle.

図１６は、本発明の実施の形態４にかかるカプセル型医療装置の一構成例を示す模式図である。図１６に示すように、この実施の形態４にかかるカプセル型医療装置５１は、上述した実施の形態１にかかるカプセル型医療装置１の注射針３に代えて注射針５３を備え、加熱部４に代えて焼灼部５４を備え、制御部１３に代えて制御部５９を備える。その他の構成は実施の形態１と同じであり、同一構成部分には同一符号を付している。   FIG. 16 is a schematic diagram illustrating a configuration example of a capsule medical apparatus according to the fourth embodiment of the present invention. As shown in FIG. 16, a capsule medical device 51 according to the fourth embodiment includes an injection needle 53 instead of the injection needle 3 of the capsule medical device 1 according to the first embodiment described above, and includes a heating unit 4. Instead of this, a cautery unit 54 is provided, and a control unit 59 is provided instead of the control unit 13. Other configurations are the same as those of the first embodiment, and the same reference numerals are given to the same components.

注射針５３は、金属等によって形成される硬質の中空針であり、穿刺した体内部位の収縮力によって縮小変形するものではない。また、注射針５３の後端部にはチューブ１０ｂが取り付けられ、注射針５３は、このチューブ１０ｂを介して駆動弁９と連通する。この注射針５３の後端部近傍には支持部５が取り付けられ、注射針５３は、上述した実施の形態１における注射針３と同様に駆動部６の作用によってカプセル型筐体２から突没する。なお、注射針５３は、上述した実施の形態１における注射針３と同様の中空針構造を有する。   The injection needle 53 is a hard hollow needle formed of metal or the like, and does not shrink and deform due to the contraction force of the punctured body part. A tube 10b is attached to the rear end portion of the injection needle 53, and the injection needle 53 communicates with the drive valve 9 through the tube 10b. The support portion 5 is attached in the vicinity of the rear end portion of the injection needle 53, and the injection needle 53 protrudes and retracts from the capsule-type housing 2 by the action of the drive portion 6 in the same manner as the injection needle 3 in the first embodiment described above. To do. The injection needle 53 has the same hollow needle structure as the injection needle 3 in the first embodiment described above.

焼灼部５４は、注射針５３による体内部位の穿刺穴を焼灼処理によって閉塞状態にする閉塞手段として機能する。具体的には、焼灼部５４は、注射針５３の突没口である開口部２ｃの近傍に、この開口部２ｃを囲む態様でカプセル型筐体２に配置される。焼灼部５４は、生体組織を焼灼する焼灼機能部として抵抗発熱素子等を備え、カプセル型筐体２の外表面に露出する。かかる焼灼部５４は、注射針５３を穿刺した体内部位と接触し、制御部５９によって供給された電力をもとに、この体内部位における注射針５３の周囲の生体組織を焼灼処理する。これによって、焼灼部５４は、この注射針５３による体内部位の穿刺穴を閉塞状態にする。なお、この実施の形態４において、体内部位の穿刺穴の閉塞状態とは、この穿刺穴周囲の生体組織が焼灼部５４の焼灼処理によって凝固しつつ穿刺穴を閉塞した状態である。   The cauterization part 54 functions as a closing means for closing the puncture hole in the body part by the injection needle 53 by cauterization. Specifically, the cautery portion 54 is disposed in the capsule casing 2 in a manner surrounding the opening 2 c in the vicinity of the opening 2 c that is a projecting / retracting opening of the injection needle 53. The cauterization unit 54 includes a resistance heating element or the like as an ablation function unit for cauterizing a living tissue, and is exposed on the outer surface of the capsule-type casing 2. The ablation unit 54 contacts the body part punctured with the injection needle 53 and cauterizes the living tissue around the injection needle 53 in the body part based on the power supplied by the control unit 59. As a result, the cautery unit 54 closes the puncture hole in the body part by the injection needle 53. In the fourth embodiment, the closed state of the puncture hole in the body part is a state in which the living tissue around the puncture hole is solidified by the cauterization process of the cauterization part 54 and the puncture hole is closed.

制御部５９は、体内部位に穿刺した状態の注射針５３周囲の生体組織を焼灼処理して穿刺穴を閉塞状態にするように焼灼部５４を制御する。この場合、制御部５９は、焼灼部５４に電力を供給するタイミングを制御することによって焼灼部５４の焼灼処理タイミングを制御する。また、制御部５９は、焼灼部５４に対する通電量および通電時間を制御することによって、焼灼部５４の焼灼温度および焼灼時間を各々制御する。なお、制御部５９は、かかる焼灼部５４の制御以外、上述した実施の形態１にかかるカプセル型医療装置１の制御部１３と同様の機能を有する。   The control unit 59 controls the cauterization unit 54 so as to cauterize the living tissue around the injection needle 53 in the state of being punctured in the body part so as to close the puncture hole. In this case, the control unit 59 controls the ablation processing timing of the ablation unit 54 by controlling the timing of supplying power to the ablation unit 54. The control unit 59 controls the ablation temperature and the ablation time of the ablation unit 54 by controlling the energization amount and energization time for the ablation unit 54, respectively. The control unit 59 has the same function as the control unit 13 of the capsule medical apparatus 1 according to the first embodiment described above, except for the control of the cauterization unit 54.

つぎに、被検体内部における所望部位の一例である患部に薬液を注射する場合を例示して、本発明の実施の形態４にかかるカプセル型医療装置５１の動作を具体的に説明する。図１７は、注射針周囲の生体組織の焼灼処理によって体内部位の穿刺穴が閉塞する状態を示す模式図である。以下では、図１７を参照しつつ、注射針５３による患部１５の穿刺穴１６を閉塞状態にする際のカプセル型医療装置５１の動作を説明する。なお、この実施の形態４にかかるカプセル型医療装置５１の動作は、体内部位の穿刺穴を閉塞する際の動作以外、上述した実施の形態１にかかるカプセル型医療装置１と同様である。   Next, the operation of the capsule medical device 51 according to the fourth embodiment of the present invention will be specifically described by exemplifying a case where a drug solution is injected into an affected part, which is an example of a desired site inside the subject. FIG. 17 is a schematic diagram showing a state where the puncture hole in the body part is blocked by the cauterization process of the living tissue around the injection needle. Hereinafter, the operation of the capsule medical device 51 when the puncture hole 16 of the affected part 15 is closed by the injection needle 53 will be described with reference to FIG. The operation of the capsule medical device 51 according to the fourth embodiment is the same as that of the capsule medical device 1 according to the first embodiment described above, except for the operation when closing the puncture hole in the body part.

患部１５に穿刺した注射針５３を介して患部１５の内部に薬液７を注入し終えたカプセル型医療装置５１において、制御部５９は、図１７に示すように、患部１５に注射針５３を穿刺した状態を維持するように駆動部６を制御しつつ、この注射針５３の周囲の生体組織１７を所定の時間焼灼処理するように焼灼部５４を制御する。具体的には、制御部５９は、上述した駆動弁９を閉駆動させたタイミングに、焼灼部５４に電力を供給し、その後、所定の時間、焼灼部５４に電力を供給し続ける。   In the capsule medical device 51 in which the medicinal solution 7 has been injected into the affected part 15 through the injection needle 53 punctured in the affected part 15, the control unit 59 punctures the affected part 15 with the injection needle 53 as shown in FIG. While controlling the drive unit 6 so as to maintain the state, the cauterization unit 54 is controlled so as to cauterize the living tissue 17 around the injection needle 53 for a predetermined time. Specifically, the control unit 59 supplies power to the cauterization unit 54 at the timing when the drive valve 9 described above is driven to close, and then continues to supply power to the cauterization unit 54 for a predetermined time.

焼灼部５４は、注射針５３を穿刺した患部１５と接触した状態であり、かかる制御部５９の制御に基づいて、この穿刺状態である注射針５３の周囲の生体組織１７を所定の時間焼灼処理する。かかる焼灼部５４によって所定の時間焼灼処理された生体組織１７は、凝固しつつ、この注射針５３による患部１５の穿刺穴１６を閉塞状態にする。かかる凝固状態の生体組織１７は、この患部１５の内部（薬液７側）と穿刺穴１６の外部（カプセル型医療装置５１側）とを完全に遮断する。   The cautery unit 54 is in contact with the affected part 15 where the injection needle 53 has been punctured. Based on the control of the control unit 59, the living tissue 17 around the injection needle 53 in the puncture state is cauterized for a predetermined time. To do. The living tissue 17 subjected to the cauterization process for a predetermined time by the cauterization unit 54 is solidified and the puncture hole 16 of the affected part 15 by the injection needle 53 is closed. The coagulated biological tissue 17 completely blocks the inside of the affected area 15 (medical solution 7 side) and the outside of the puncture hole 16 (capsule type medical device 51 side).

その後、制御部５９は、焼灼部５４の焼灼処理を開始してから所定の時間が経過したタイミングに、焼灼部５４への電力供給を停止して焼灼部５４の焼灼処理を終了させる。続いて、制御部５９は、上述した実施の形態１の場合と同様に、この患部１５から注射針５３を抜き取ってカプセル型筐体２の内部に注射針５３を収納するように駆動部６を制御する。   Then, the control part 59 stops the electric power supply to the cauterization part 54, and the cauterization process of the cauterization part 54 is complete | finished at the timing when predetermined time passed since the cauterization process of the cauterization part 54 was started. Subsequently, as in the case of the first embodiment described above, the control unit 59 pulls out the injection needle 53 from the affected part 15 and houses the drive unit 6 so that the injection needle 53 is accommodated in the capsule housing 2. Control.

ここで、注射針５３を抜き取られた患部１５の穿刺穴（穿刺跡）１６は、上述した凝固状態の生体組織１７によって閉塞状態である。このため、患部１５は、このように注射針５３が抜き取られた後であっても、この穿刺穴１６から薬液７を漏出させることなく、内部に薬液７を留める。この結果、患部１５内部の薬液７は、この被検体内部における患部１５以外の体内部位に漏れ広がることがない。   Here, the puncture hole (puncture mark) 16 of the affected part 15 from which the injection needle 53 has been removed is in a closed state by the above-described coagulated biological tissue 17. For this reason, even after the injection needle 53 is pulled out in this way, the affected part 15 keeps the drug solution 7 inside without leaking the drug solution 7 from the puncture hole 16. As a result, the medicinal solution 7 inside the affected part 15 does not leak and spread in the body part other than the affected part 15 inside the subject.

以上、説明したように、本発明の実施の形態４では、カプセル型筐体の外表面に露出する態様で焼灼部を配置し、この焼灼部が、体内部位に穿刺した状態である注射針の周囲の生体組織を焼灼処理することによって、この注射針による体内部位の穿刺穴を閉塞状態にするようにし、その他を実施の形態１と同様に構成した。このため、焼灼部の焼灼処理によって凝固した生体組織によって体内部位の穿刺穴を完全に閉塞することができ、上述した実施の形態１の場合と同様の作用効果を享受するとともに、より確実に体内部位の穿刺穴からの注入液体の漏出を防止可能なカプセル型医療装置を実現することができる。   As described above, in the fourth embodiment of the present invention, the cautery part is arranged in a manner exposed on the outer surface of the capsule-type housing, and the cautery part is in a state of being punctured into a body part. The surrounding living tissue was cauterized so that the puncture hole in the body part by the injection needle was closed, and the others were configured in the same manner as in the first embodiment. For this reason, the puncture hole in the body part can be completely closed by the living tissue solidified by the cauterization process of the cauterization part, and the same operational effect as in the case of the above-described first embodiment can be enjoyed, and more reliably in the body. It is possible to realize a capsule medical device capable of preventing leakage of the injected liquid from the puncture hole at the site.

（実施の形態４の変形例１）
つぎに、本発明の実施の形態４の変形例１について説明する。上述した実施の形態４では、カプセル型筐体２の外壁部（具体的には注射針５３の突没口である開口部２ｃの近傍）に配置した焼灼部５４によって、穿刺状態である注射針５３の周囲の生体組織を焼灼処理して穿刺穴１６を閉塞状態にしていたが、この実施の形態４の変形例１では、焼灼部として機能を兼ね備えた注射針を備え、この注射針を穿刺した体内部位の穿刺穴を、この穿刺状態の注射針の焼灼処理によって閉塞状態にしている。 (Modification 1 of Embodiment 4)
Next, Modification 1 of Embodiment 4 of the present invention will be described. In the above-described fourth embodiment, the injection needle in the puncture state is provided by the cautery portion 54 disposed on the outer wall portion of the capsule-type housing 2 (specifically, in the vicinity of the opening 2c that is the projecting and retracting opening of the injection needle 53). The living tissue around 53 is cauterized to close the puncture hole 16, but in the first modification of the fourth embodiment, an injection needle having a function as an ablation part is provided, and this injection needle is punctured. The puncture hole in the in-vivo site is closed by cauterization of the punctured injection needle.

図１８は、本発明の実施の形態４の変形例１にかかるカプセル型医療装置の一構成例を示す模式図である。図１８に示すように、この実施の形態４の変形例１にかかるカプセル型医療装置６１は、上述した実施の形態４にかかるカプセル型医療装置５１の注射針５３に代えて、生体組織の焼灼処理機能を兼ね備えた注射針６３を備え、上述した焼灼部５４を備えていない。なお、かかるカプセル型医療装置６１において、制御部５９は、上述した焼灼部５４の代わりに注射針６３に電力を供給して、この注射針６３による生体組織の焼灼処理を制御する。その他の構成は実施の形態４と同じであり、同一構成部分には同一符号を付している。   FIG. 18 is a schematic diagram illustrating a configuration example of a capsule medical apparatus according to the first modification of the fourth embodiment of the present invention. As shown in FIG. 18, the capsule medical device 61 according to the first modification of the fourth embodiment is an ablation of living tissue instead of the injection needle 53 of the capsule medical device 51 according to the fourth embodiment described above. The injection needle 63 having a processing function is provided, and the above-described cautery portion 54 is not provided. In this capsule medical device 61, the control unit 59 supplies power to the injection needle 63 instead of the above-described cauterization unit 54, and controls the cauterization process of the living tissue by the injection needle 63. Other configurations are the same as those of the fourth embodiment, and the same components are denoted by the same reference numerals.

注射針６３は、体内部位に薬液等の液体を注射するための中空針としての機能と、体内部位の穿刺穴を焼灼処理によって閉塞状態にする閉塞手段としての機能とを兼ね備える。具体的には、注射針６３は、電力供給によって発熱する抵抗発熱部材によって形成される硬質の中空針であり、穿刺した体内部位の収縮力によって縮小変形するものではない。また、注射針６３の後端部にはチューブ１０ｂが取り付けられ、注射針６３は、このチューブ１０ｂを介して駆動弁９と連通する。この注射針６３の後端部近傍には支持部５が取り付けられ、注射針６３は、上述した実施の形態４における注射針５３と同様に駆動部６の作用によってカプセル型筐体２から突没する。なお、注射針６３は、上述した実施の形態４における注射針５３と同様の中空針構造を有する。また、チューブ１０ｂは、耐熱素材からなり、注射針６３の発熱の影響を受けない。   The injection needle 63 has a function as a hollow needle for injecting a liquid such as a drug solution into a body part and a function as a closing means for closing the puncture hole in the body part by cauterization. Specifically, the injection needle 63 is a hard hollow needle formed by a resistance heating member that generates heat when power is supplied, and is not deformed by contraction force of the punctured internal body part. A tube 10b is attached to the rear end of the injection needle 63, and the injection needle 63 communicates with the drive valve 9 through the tube 10b. The support portion 5 is attached in the vicinity of the rear end portion of the injection needle 63, and the injection needle 63 protrudes and retracts from the capsule-type housing 2 by the action of the drive portion 6 in the same manner as the injection needle 53 in the fourth embodiment described above. To do. The injection needle 63 has a hollow needle structure similar to the injection needle 53 in the fourth embodiment described above. The tube 10b is made of a heat-resistant material and is not affected by the heat generated by the injection needle 63.

なお、この実施の形態４の変形例１にかかるカプセル型医療装置６１において、制御部５９は、体内部位に穿刺した状態の注射針６３周囲の生体組織を焼灼処理して穿刺穴を閉塞状態にするように注射針６３を制御する。この場合、制御部５９は、上述した実施の形態４における焼灼部５４の制御と同様に、注射針６３に対する電力の供給タイミングを制御することによって注射針６３の焼灼処理タイミングを制御する。また、制御部５９は、注射針６３に対する通電量および通電時間を制御することによって、注射針６３による生体組織の焼灼温度および焼灼時間を各々制御する。   In the capsule medical device 61 according to the first modification of the fourth embodiment, the control unit 59 cauterizes the living tissue around the injection needle 63 that has been punctured into the body part to close the puncture hole. Thus, the injection needle 63 is controlled. In this case, the control unit 59 controls the cauterization process timing of the injection needle 63 by controlling the power supply timing to the injection needle 63 in the same manner as the control of the cauterization unit 54 in the fourth embodiment described above. Further, the control unit 59 controls the ablation temperature and the ablation time of the living tissue by the injection needle 63 by controlling the energization amount and the energization time for the injection needle 63, respectively.

ここで、かかる焼灼処理機能を兼ね備えた注射針６３は、上述した患部１５等の所望の体内部位に穿刺した状態において、制御部５９から所定時間供給される電力をもとに、この体内部位の穿刺穴周囲の生体組織（すなわち穿刺状態の注射針６３周囲の生体組織）を所定時間焼灼処理する。かかる注射針６３によって焼灼処理された穿刺穴周囲の生体組織は、上述した実施の形態４の場合と同様に、凝固しつつ、この体内部位の穿刺穴を閉塞状態にする。この場合、かかる凝固状態の生体組織は、この体内部位の内部（注入薬液側）と穿刺穴の外部（カプセル型医療装置６１側）とを完全に遮断する。このように穿刺穴を閉塞状態にした体内部位は、穿刺穴から注射針６３が抜き取られた後であっても、この穿刺穴から薬液７を漏出させることなく、内部に薬液７を留める。   Here, the injection needle 63 having such a cauterization function functions in the state of puncturing a desired internal body part such as the above-mentioned affected part 15 based on the electric power supplied from the control unit 59 for a predetermined time. The living tissue around the puncture hole (that is, the living tissue around the punctured injection needle 63) is cauterized for a predetermined time. The living tissue around the puncture hole cauterized by the injection needle 63 is solidified and closes the puncture hole in the body part as in the case of the fourth embodiment described above. In this case, the coagulated biological tissue completely blocks the inside of the body part (injected drug solution side) and the outside of the puncture hole (capsule type medical device 61 side). In this way, the body part with the puncture hole in the closed state retains the drug solution 7 inside without causing the drug solution 7 to leak out from the puncture hole even after the injection needle 63 is extracted from the puncture hole.

以上、説明したように、本発明の実施の形態４の変形例１では、体内部位に薬液等の液体を注射する中空針としての機能と、穿刺穴周囲の生体組織を焼灼処理する焼灼部としての機能とを兼ね備えた注射針を備え、この注射針を穿刺した状態の体内部位の穿刺穴周囲の生体組織をこの注射針の焼灼処理によって凝固させて、この穿刺穴を閉塞状態にするようにし、その他を実施の形態４と同様に構成した。このため、上述した実施の形態４の場合と同様の作用効果を享受するとともに、部品点数を低減して、組立し易さの向上および組立コストの低減を促進できるカプセル型医療装置を実現することができる。   As described above, in the first modification of the fourth embodiment of the present invention, the function as a hollow needle that injects a liquid such as a drug solution into a body part, and the cauterization unit that cauterizes the living tissue around the puncture hole. And the living tissue around the puncture hole in the body part where the injection needle is punctured is solidified by cauterization of the injection needle so that the puncture hole is closed. Other configurations are the same as those in the fourth embodiment. For this reason, while enjoying the same operation effect as the case of Embodiment 4 mentioned above, the number of parts is reduced and the capsule type medical device which can promote improvement of assembly ease and reduction of assembly cost is realized. Can do.

（実施の形態４の変形例２）
つぎに、本発明の実施の形態４の変形例２について説明する。上述した実施の形態４では、カプセル型筐体２の外壁部（具体的には注射針５３の突没口である開口部２ｃの近傍）に配置した焼灼部５４によって、穿刺状態である注射針５３の周囲の生体組織を焼灼処理して穿刺穴を閉塞状態にしていたが、この実施の形態４の変形例２では、カプセル型筐体２から突没可能な焼灼部を備え、カプセル型筐体２から突出させた焼灼部を体内部位に接触させ、この焼灼部によって注射針周辺の生体組織を焼灼処理して、この体内部位の穿刺穴を閉塞状態にしている。 (Modification 2 of Embodiment 4)
Next, a second modification of the fourth embodiment of the present invention will be described. In the above-described fourth embodiment, the injection needle in the puncture state is provided by the cautery portion 54 disposed on the outer wall portion of the capsule-type housing 2 (specifically, in the vicinity of the opening 2c that is the projecting and retracting opening of the injection needle 53). The living tissue around 53 is cauterized to close the puncture hole. In the second modification of the fourth embodiment, a cautery part that can protrude and retract from the capsule-type casing 2 is provided. The cauterized part protruding from the body 2 is brought into contact with the body part, and the living tissue around the injection needle is cauterized by the cauterized part, thereby closing the puncture hole in the body part.

図１９は、本発明の実施の形態４の変形例２にかかるカプセル型医療装置の一構成例を示す模式図である。図１９に示すように、この実施の形態４の変形例２にかかるカプセル型医療装置７１は、上述した実施の形態４にかかるカプセル型医療装置５１の焼灼部５４に代えて突没可能な焼灼部７４を備え、制御部５９に代えて制御部７９を備え、さらに、この焼灼部７４を支持する支持部７５と、カプセル型筐体２から焼灼部７４を突没させる駆動部７６とを備える。その他の構成は実施の形態４と同じであり、同一構成部分には同一符号を付している。   FIG. 19 is a schematic diagram illustrating a configuration example of a capsule medical apparatus according to the second modification of the fourth embodiment of the present invention. As shown in FIG. 19, the capsule medical device 71 according to the second modification of the fourth embodiment is capable of projecting and sinking instead of the cautery portion 54 of the capsule medical device 51 according to the fourth embodiment described above. A control unit 79 instead of the control unit 59, and a support unit 75 for supporting the cauterization unit 74 and a drive unit 76 for projecting and retracting the cauterization unit 74 from the capsule housing 2. . Other configurations are the same as those of the fourth embodiment, and the same components are denoted by the same reference numerals.

焼灼部７４は、注射針５３による体内部位の穿刺穴を焼灼処理によって閉塞状態にする閉塞手段として機能する。具体的には、焼灼部７４は、電力供給によって発熱する抵抗発熱部材を用いて実現され、内部に注射針５３を挿通可能な筒形状に形成される。焼灼部７４は、支持部７５によって支持され、この支持部７５と接続された駆動部７６の作用によって、カプセル型筐体２の開口部２ｃから突没する。かかる焼灼部７４は、カプセル型筐体２から突出して穿刺対象の体内部位と接触し、この体内部位の生体組織、詳細には、この体内部位に穿刺した状態の注射針５３の周囲の生体組織（すなわち穿刺穴周囲の生体組織）を、制御部７９からの供給電力をもとに焼灼処理する。これによって、焼灼部７４は、上述した実施の形態４の場合と同様に、この注射針５３による体内部位の穿刺穴を閉塞状態にする。   The cauterization part 74 functions as a closing means for closing the puncture hole in the body part by the injection needle 53 by cauterization. Specifically, the cautery unit 74 is realized by using a resistance heating member that generates heat by supplying power, and is formed in a cylindrical shape into which the injection needle 53 can be inserted. The cautery part 74 is supported by the support part 75, and protrudes and sinks from the opening 2 c of the capsule housing 2 by the action of the drive part 76 connected to the support part 75. The cautery unit 74 protrudes from the capsule housing 2 and comes into contact with the internal body part to be punctured, and the biological tissue of this internal body part, specifically, the biological tissue around the injection needle 53 in the state of puncturing the internal body part. (That is, the living tissue around the puncture hole) is cauterized based on the power supplied from the control unit 79. As a result, the cauterization unit 74 closes the puncture hole in the body part by the injection needle 53 as in the case of the fourth embodiment described above.

かかる焼灼部７４の後端部近傍には支持部７５が固定される。支持部７５は、筒形状の焼灼部７４の内部に注射針５３を挿通した態様であり且つカプセル型筐体２の開口部２ｃを通して焼灼部７４が突没可能な態様で焼灼部７４を支持する。かかる支持部７５は、駆動部７６と接続される。   A support portion 75 is fixed in the vicinity of the rear end portion of the cautery portion 74. The support part 75 is a mode in which the injection needle 53 is inserted into the cylindrical cautery part 74 and supports the cautery part 74 in a mode in which the cautery part 74 can project and retract through the opening 2c of the capsule-type housing 2. . The support part 75 is connected to the drive part 76.

駆動部７６は、注射針５３を突没させる駆動部６とは独立して動作可能なものであり、カプセル型筐体２の開口部２ｃを介して焼灼部７４を突没させる焼灼部駆動手段として機能する。具体的には、駆動部７６は、リニアアクチュエータ等を用いて実現される。駆動部７６は、上述した支持部７５を介して焼灼部７４を注射針５３の突没方向（図１９に示す太線矢印方向）と同じ方向に往復動作させる。かかる駆動部７６は、制御部７９の制御に基づいて、注射針５３とともに焼灼部７４をカプセル型筐体２から突出させて焼灼部７４を穿刺対象の体内部位に接触させ、この体内部位に穿刺した状態の注射針５３の周囲の生体組織を焼灼部７４が焼灼処理する期間、この体内部位に焼灼部７４を接触させた状態を維持する。この場合、駆動部７６は、注射針５３を穿刺前に穿刺対象の体内部位に焼灼部７４を接触させてもよいし、注射針５３を穿刺した状態の体内部位に焼灼部７４を接触させてもよい。また、かかる駆動部７６は、制御部７９の制御に基づいて、この体内部位の穿刺穴周囲の生体組織を焼灼部７４が焼灼処理し終えた後に、カプセル型筐体２の内部に焼灼部７４を収納する。   The drive unit 76 is operable independently of the drive unit 6 for projecting and retracting the injection needle 53, and ablation unit drive means for projecting and retracting the cautery unit 74 through the opening 2 c of the capsule housing 2. Function as. Specifically, the drive unit 76 is realized using a linear actuator or the like. The drive unit 76 causes the cautery unit 74 to reciprocate in the same direction as the protruding and retracting direction of the injection needle 53 (the direction of the thick line arrow shown in FIG. 19) via the support unit 75 described above. Based on the control of the control unit 79, the driving unit 76 causes the cautery unit 74 together with the injection needle 53 to protrude from the capsule-type housing 2 so that the cautery unit 74 is brought into contact with a body part to be punctured, and punctures the body part During the period in which the cauterization unit 74 cauterizes the living tissue around the injection needle 53 in the state in which the cautery unit 53 is in the state, the state where the cauterization unit 74 is brought into contact with the internal body part is maintained. In this case, the drive unit 76 may bring the cauterization part 74 into contact with the internal part of the puncture target before the injection needle 53 is punctured, or bring the cauterization part 74 into contact with the internal part of the state where the injection needle 53 has been punctured. Also good. In addition, the drive unit 76, based on the control of the control unit 79, after the cauterization unit 74 finishes cauterizing the living tissue around the puncture hole in the body part, the cauterization unit 74 is placed inside the capsule-type housing 2. Storing.

制御部７９は、体内部位に穿刺した状態の注射針５３周囲の生体組織を焼灼処理して穿刺穴を閉塞状態にするように焼灼部７４を制御する。この場合、制御部７９は、上述した実施の形態４における焼灼部５４の制御と同様に、焼灼部７４に対する電力の供給タイミングを制御することによって焼灼部７４の焼灼処理タイミングを制御し、焼灼部７４に対する通電量および通電時間を制御することによって焼灼部７４の焼灼温度および焼灼時間を各々制御する。また、制御部７９は、注射針５３の突出動作と焼灼部７４の突出動作とを行うように駆動部６および駆動部７６を制御し、体内部位の穿刺穴周囲の生体組織を焼灼部７４によって焼灼処理完了後に焼灼部７４をカプセル型筐体２の内部に収納するように駆動部７６を制御する。なお、制御部７９は、かかる焼灼部７４および駆動部７６の制御以外、上述した実施の形態４にかかるカプセル型医療装置５１の制御部５９と同様の機能を有する。   The control unit 79 controls the cauterization unit 74 so as to cauterize the living tissue around the injection needle 53 in a state where the body part has been punctured to close the puncture hole. In this case, the control unit 79 controls the ablation processing timing of the ablation unit 74 by controlling the power supply timing to the ablation unit 74, similarly to the control of the ablation unit 54 in the fourth embodiment described above, and the ablation unit The ablation temperature and ablation time of the ablation unit 74 are controlled by controlling the energization amount and the energization time for 74, respectively. Further, the control unit 79 controls the driving unit 6 and the driving unit 76 so as to perform the protruding operation of the injection needle 53 and the protruding operation of the cauterizing unit 74, and the abdominal tissue around the puncture hole in the body part is caused by the cauterizing unit 74. After the cauterization process is completed, the drive unit 76 is controlled so that the cautery unit 74 is accommodated in the capsule casing 2. The control unit 79 has the same functions as the control unit 59 of the capsule medical device 51 according to the fourth embodiment described above, except for the control of the cauterization unit 74 and the drive unit 76.

つぎに、被検体内部における所望部位の一例である患部に薬液を注射する場合を例示して、本発明の実施の形態４の変形例２にかかるカプセル型医療装置７１の動作を具体的に説明する。図２０は、注射針周囲の生体組織の焼灼処理によって体内部位の穿刺穴が閉塞する状態を示す模式図である。以下では、図２０を参照しつつ、注射針５３による患部１５の穿刺穴１６を閉塞状態にする際のカプセル型医療装置７１の動作と、カプセル型筐体２の内部に焼灼部７４を収納する際のカプセル型医療装置７１の動作とを説明する。なお、かかるカプセル型医療装置７１の動作は、焼灼部７４に関する動作（穿刺穴の閉塞動作、焼灼部７４の収納動作等）以外、上述した実施の形態４にかかるカプセル型医療装置５１と同様である。   Next, the operation of the capsule medical device 71 according to the second modification of the fourth embodiment of the present invention is specifically described by exemplifying a case where a drug solution is injected into an affected part, which is an example of a desired site inside the subject. To do. FIG. 20 is a schematic diagram showing a state where the puncture hole in the body part is closed by cauterization of the living tissue around the injection needle. In the following, referring to FIG. 20, the operation of the capsule medical device 71 when the puncture hole 16 of the affected part 15 is closed by the injection needle 53 and the cautery part 74 is housed inside the capsule housing 2. The operation of the capsule medical device 71 will be described. The operation of the capsule medical device 71 is the same as that of the capsule medical device 51 according to the above-described fourth embodiment, except for the operation related to the cautery unit 74 (the puncture hole closing operation, the cautery unit 74 storing operation, etc.). is there.

なお、被検体内部の患部１５に到達したカプセル型医療装置７１において、制御部７９は、上述した外部装置からの制御信号に基づいて、まず、カプセル型筐体２から焼灼部７４とともに注射針５３を突き出すように駆動部６および駆動部７６を制御する。この場合、駆動部７６は、注射針５３の突出動作を阻害しないように焼灼部７４をカプセル型筐体２から突出させて、穿刺対象の患部１５に焼灼部７４を接触させる。駆動部６は、実施の形態４の場合と同様にカプセル型筐体２から注射針５３を突き出して、患部１５に注射針５３を穿刺する。注射針５３は、この焼灼部７４の内部を通ってカプセル型筐体２から突出し、患部１５に突き刺さる。制御部７９は、実施の形態４の場合と同様に、この穿刺状態の注射針５３を介して必要量の薬液７を患部１５の内部に注入するように駆動弁９を制御する。この結果、カプセル型医療装置７１は、この患部１５の内部に必要量の薬液７を注入し終える。   Note that in the capsule medical device 71 that has reached the affected part 15 inside the subject, the control unit 79 starts with the injection needle 53 together with the cauterization unit 74 from the capsule housing 2 based on the control signal from the external device described above. The drive unit 6 and the drive unit 76 are controlled so as to protrude. In this case, the drive unit 76 causes the cauterization unit 74 to protrude from the capsule-type housing 2 so as not to hinder the protruding operation of the injection needle 53, and brings the cauterization unit 74 into contact with the affected part 15 to be punctured. As in the case of the fourth embodiment, the drive unit 6 projects the injection needle 53 from the capsule-type housing 2 and punctures the affected part 15 with the injection needle 53. The injection needle 53 protrudes from the capsule housing 2 through the inside of the cauterization part 74 and pierces the affected part 15. As in the case of the fourth embodiment, the control unit 79 controls the drive valve 9 so as to inject a required amount of the drug solution 7 into the affected part 15 through the punctured injection needle 53. As a result, the capsule medical device 71 finishes injecting the required amount of the drug solution 7 into the affected area 15.

このように患部１５の内部に必要量の薬液７を注入し終えたカプセル型医療装置７１において、制御部７９は、図２０に示すように、患部１５に注射針５３を穿刺した状態を維持するように駆動部６を制御しつつ、この注射針５３の周囲の生体組織１７を所定の時間焼灼処理するように焼灼部７４を制御する。具体的には、制御部７９は、上述した駆動弁９を閉駆動させたタイミングに、焼灼部７４に電力を供給し、その後、所定の時間、焼灼部７４に電力を供給し続ける。   In the capsule medical device 71 in which the required amount of the drug solution 7 has been injected into the affected part 15 as described above, the control unit 79 maintains the state where the injection needle 53 is punctured into the affected part 15 as shown in FIG. While controlling the drive unit 6 as described above, the cauterization unit 74 is controlled so that the living tissue 17 around the injection needle 53 is cauterized for a predetermined time. Specifically, the control unit 79 supplies power to the cauterization unit 74 at the timing when the drive valve 9 described above is driven to close, and then continues to supply power to the cauterization unit 74 for a predetermined time.

焼灼部７４は、注射針５３を穿刺した患部１５と接触した状態であり、かかる制御部７９の制御に基づいて、この穿刺状態である注射針５３の周囲の生体組織１７を所定の時間焼灼処理する。かかる焼灼部７４によって所定の時間焼灼処理された生体組織１７は、実施の形態４の場合と同様に凝固しつつ、この注射針５３による患部１５の穿刺穴１６を閉塞状態にする。かかる凝固状態の生体組織１７は、この患部１５の内部（薬液７側）と穿刺穴１６の外部（カプセル型医療装置７１側）とを完全に遮断する。   The cautery unit 74 is in contact with the affected part 15 where the injection needle 53 has been punctured, and based on the control of the control unit 79, the living tissue 17 around the injection needle 53 in the puncture state is cauterized for a predetermined time. To do. The living tissue 17 that has been cauterized for a predetermined time by the cauterization unit 74 is solidified in the same manner as in the fourth embodiment, and the puncture hole 16 of the affected part 15 by the injection needle 53 is closed. The coagulated biological tissue 17 completely blocks the inside of the affected area 15 (medical solution 7 side) and the outside of the puncture hole 16 (capsule medical device 71 side).

その後、制御部７９は、焼灼部７４の焼灼処理を開始してから所定の時間が経過したタイミングに、焼灼部７４への電力供給を停止して焼灼部７４の焼灼処理を終了させる。続いて、制御部７９は、この患部１５から注射針５３を抜き取ってカプセル型筐体２の内部に注射針５３を収納するように駆動部６を制御する。この場合、注射針５３は、焼灼部７４の内部を通ってカプセル型筐体２の内部に移動する。また、制御部７９は、患部１５の焼灼処理（すなわち穿刺穴１６の閉塞処理）を完了した焼灼部７４をカプセル型筐体２の内部に収納するように駆動部７６を制御する。この場合、駆動部７６は、注射針５３がカプセル型筐体２の内部に収納された後に焼灼部７４をカプセル型筐体２の内部に収納してもよいし、注射針５３とともに焼灼部７４をカプセル型筐体２の内部に収納してもよい。   Then, the control part 79 stops the electric power supply to the cauterization part 74, and the cauterization process of the cauterization part 74 is complete | finished at the timing when predetermined time passed since the cauterization process of the cauterization part 74 was started. Subsequently, the control unit 79 controls the drive unit 6 so as to extract the injection needle 53 from the affected part 15 and store the injection needle 53 in the capsule housing 2. In this case, the injection needle 53 moves to the inside of the capsule casing 2 through the inside of the cautery unit 74. In addition, the control unit 79 controls the drive unit 76 so that the cauterization unit 74 that has completed the cauterization process of the affected part 15 (that is, the closing process of the puncture hole 16) is accommodated in the capsule-type housing 2. In this case, the drive unit 76 may store the cauterization unit 74 in the capsule type housing 2 after the injection needle 53 is stored in the capsule type housing 2, or the cauterization unit 74 together with the injection needle 53. May be stored inside the capsule-type housing 2.

ここで、注射針５３を抜き取られた患部１５の穿刺穴（穿刺跡）１６は、上述した凝固状態の生体組織１７によって閉塞状態である。このため、患部１５は、このように注射針５３が抜き取られた後であっても、この穿刺穴１６から薬液７を漏出させることなく、内部に薬液７を留める。この結果、患部１５内部の薬液７は、この被検体内部における患部１５以外の体内部位に漏れ広がることがない。   Here, the puncture hole (puncture mark) 16 of the affected part 15 from which the injection needle 53 has been removed is in a closed state by the above-described coagulated biological tissue 17. For this reason, even after the injection needle 53 is pulled out in this way, the affected part 15 keeps the drug solution 7 inside without leaking the drug solution 7 from the puncture hole 16. As a result, the medicinal solution 7 inside the affected part 15 does not leak and spread in the body part other than the affected part 15 inside the subject.

以上、説明したように、本発明の実施の形態４の変形例２では、駆動部の作用によって突没可能な焼灼部を備え、カプセル型筐体から突出させた焼灼部を穿刺対象の体内部位に接触させ、この焼灼部が、この体内部位に穿刺した状態である注射針の周囲の生体組織（すなわち穿刺穴周囲の生体組織）を焼灼処理することによって、この注射針による体内部位の穿刺穴を閉塞状態にするようにし、その他を実施の形態４と同様に構成した。このため、上述した実施の形態４の場合と同様の作用効果を享受するとともに、穿刺対象の体内部位に焼灼部を確実に接触させることができ、この結果、より確実に穿刺穴周囲の生体組織を焼灼処理によって凝固することが可能なカプセル型医療装置を実現することができる。   As described above, in the second modification of the fourth embodiment of the present invention, the cauterization part that can be protruded and retracted by the action of the drive part is provided, and the ablation part that protrudes from the capsule-type housing is the body part of the puncture target. The cauterization part is cauterized on the living tissue around the injection needle (ie, the living tissue around the puncture hole) in a state where the cauterization part is punctured into the internal body part, so that the puncture hole in the internal site by the injection needle The other configuration is the same as in the fourth embodiment. For this reason, while enjoying the effect similar to the case of Embodiment 4 mentioned above, a cauterization part can be made to contact reliably the internal region part of puncture object, As a result, the biological tissue around a puncture hole more reliably It is possible to realize a capsule medical device that can be solidified by cauterization.

（実施の形態５）
つぎに、本発明の実施の形態５について説明する。上述した実施の形態１では、体内部位に穿刺した状態の注射針３を加熱処理によって縮小変形させて、この注射針３による体内部位の穿刺穴を閉塞状態にしていたが、この実施の形態５では、注射針を穿刺した状態の体内部位の表面を伸展させ、この体内部位の伸展状態を維持しつつ注射針を抜き取ることによって、この体内部位の穿刺穴を閉塞状態にしている。 (Embodiment 5)
Next, a fifth embodiment of the present invention will be described. In the first embodiment described above, the injection needle 3 that has been punctured into the body part is contracted and deformed by heat treatment, and the puncture hole in the body part by the injection needle 3 is in a closed state. In this case, the surface of the body part in the state where the injection needle is punctured is stretched, and the puncture hole in the body part is closed by removing the injection needle while maintaining the stretched state of the body part.

図２１は、本発明の実施の形態５にかかるカプセル型医療装置の一構成例を示す模式図である。図２１に示すように、この実施の形態５にかかるカプセル型医療装置８１は、上述した実施の形態１にかかるカプセル型医療装置１の注射針３に代えて注射針８３を備え、加熱部４に代えて組織変形機構８４を備え、制御部１３に代えて制御部８９を備える。その他の構成は実施の形態１と同じであり、同一構成部分には同一符号を付している。   FIG. 21 is a schematic diagram illustrating a configuration example of a capsule medical apparatus according to the fifth embodiment of the present invention. As shown in FIG. 21, a capsule medical device 81 according to the fifth embodiment includes an injection needle 83 instead of the injection needle 3 of the capsule medical device 1 according to the first embodiment described above, and includes a heating unit 4. Instead of this, a tissue deformation mechanism 84 is provided, and a control unit 89 is provided instead of the control unit 13. Other configurations are the same as those of the first embodiment, and the same reference numerals are given to the same components.

注射針８３は、金属等によって形成される硬質の中空針であり、穿刺した体内部位の収縮力によって縮小変形するものではない。また、注射針８３の後端部にはチューブ１０ｂが取り付けられ、注射針８３は、このチューブ１０ｂを介して駆動弁９と連通する。この注射針８３の後端部近傍には支持部５が取り付けられ、注射針８３は、上述した実施の形態１における注射針３と同様に駆動部６の作用によってカプセル型筐体２から突没する。なお、注射針８３は、上述した実施の形態１における注射針３と同様の中空針構造を有する。   The injection needle 83 is a hard hollow needle formed of metal or the like, and does not shrink and deform due to the contraction force of the punctured body part. A tube 10b is attached to the rear end portion of the injection needle 83, and the injection needle 83 communicates with the drive valve 9 through the tube 10b. The support portion 5 is attached in the vicinity of the rear end portion of the injection needle 83, and the injection needle 83 protrudes and retracts from the capsule-type casing 2 by the action of the drive portion 6 in the same manner as the injection needle 3 in the first embodiment described above. To do. The injection needle 83 has a hollow needle structure similar to the injection needle 3 in the first embodiment described above.

組織変形機構８４は、注射針８３を穿刺した状態の体内部位の表面組織（生体組織）を変形して注射針８３による体内部位の穿刺穴を閉塞状態にする閉塞手段として機能する。具体的には、組織変形機構８４は、注射針８３を穿刺した状態の体内部位の表面組織（生体組織）を伸展するための一対の高摩擦回転部８４ａ，８４ｂと、一方の高摩擦回転部８４ａの回転を他方の高摩擦回転部８４ｂに伝達する回転伝達部８４ｃと、一対の高摩擦回転部８４ａ，８４ｂを回転駆動するための駆動部８４ｄと、駆動部８４ｄの駆動力の回転方向を高摩擦回転部８４ａの回転方向に変換する回転方向変換部８４ｅとを備える。   The tissue deformation mechanism 84 functions as an occlusion means that deforms the surface tissue (biological tissue) of the body part in the state where the injection needle 83 is punctured to close the puncture hole in the body part by the injection needle 83. Specifically, the tissue deformation mechanism 84 includes a pair of high friction rotating portions 84a and 84b for extending a surface tissue (biological tissue) of a body part in a state where the injection needle 83 is punctured, and one high friction rotating portion. A rotation transmitting portion 84c for transmitting the rotation of 84a to the other high friction rotating portion 84b, a driving portion 84d for rotationally driving the pair of high friction rotating portions 84a and 84b, and the rotational direction of the driving force of the driving portion 84d. A rotation direction conversion unit 84e that converts the rotation direction of the high friction rotation unit 84a.

高摩擦回転部８４ａ，８４ｂは、体内部位の表面組織（臓器内壁等の生体組織）を擦り動かすに充分な摩擦性を有する高摩擦部材を用いて実現される。高摩擦回転部８４ａ，８４ｂは、ローラー状に形成され、互いに回転軸を平行にし且つ注射針８３の突没口である開口部２ｃを間に挟む態様でカプセル型筐体２に回転自在に配置される。かかる一対の高摩擦回転部８４ａ，８４ｂは、カプセル型筐体２の外壁面から露出し、被検体内部のカプセル型医療装置８１が穿刺対象の体内部位（注射針８３を穿刺する所望の体内部位）に到達した際、この体内部位の表面組織と接触する。   The high-friction rotating parts 84a and 84b are realized by using a high-friction member having a sufficient friction property for rubbing a surface tissue (a living tissue such as an internal wall of an organ) in a body part. The high-friction rotating parts 84a and 84b are formed in a roller shape, and are rotatably arranged on the capsule-type casing 2 in such a manner that the rotation axes are parallel to each other and the opening 2c that is a projecting / retracting port of the injection needle 83 is sandwiched therebetween. Is done. The pair of high-friction rotating parts 84a and 84b are exposed from the outer wall surface of the capsule-type housing 2, and the capsule medical device 81 inside the subject punctures an in-vivo site (a desired in-vivo site to puncture the injection needle 83). ), It comes into contact with the surface tissue of this internal part.

回転伝達部８４ｃは、無端状の高摩擦部材であり、図２１に示すように八の字の態様で高摩擦回転部８４ａ，８４ｂに取り付けられる。かかる回転伝達部８４ｃは、駆動部８４ｄの駆動力による高摩擦回転部８４ａの回転を他方の高摩擦回転部８４ｂに伝達し、これによって、一対の高摩擦回転部８４ａ，８４ｂを互いに逆回り（図２１に示す細線矢印方向）に回転させる。なお、回転伝達部８４ｃは、注射針８３の突没動作を阻害しないように、注射針８３の移動経路から外れる態様で配置される。   The rotation transmission portion 84c is an endless high friction member, and is attached to the high friction rotation portions 84a and 84b in an eight-letter manner as shown in FIG. The rotation transmitting portion 84c transmits the rotation of the high friction rotating portion 84a due to the driving force of the driving portion 84d to the other high friction rotating portion 84b, thereby rotating the pair of high friction rotating portions 84a and 84b in the opposite directions ( It is rotated in the direction of the thin line arrow shown in FIG. In addition, the rotation transmission part 84c is arrange | positioned in the aspect which remove | deviates from the movement path | route of the injection needle 83 so that the protrusion / retraction operation | movement of the injection needle 83 may not be inhibited.

駆動部８４ｄは、上述した高摩擦回転部８４ａ，８４ｂを回転させるためのものであり、回転アクチュエータ等を用いて実現される。駆動部８４ｄは、制御部８９の制御に基づいて駆動し、一対の高摩擦回転部８４ａ，８４ｂの回転に必要な駆動力を生成する。かかる駆動部８４ｄの駆動軸には、回転方向変換部８４ｅと接続される。   The drive unit 84d is for rotating the high-friction rotating units 84a and 84b described above, and is realized using a rotary actuator or the like. The drive unit 84d is driven based on the control of the control unit 89, and generates a drive force necessary for the rotation of the pair of high friction rotation units 84a and 84b. The drive shaft of the drive unit 84d is connected to the rotation direction conversion unit 84e.

回転方向変換部８４ｅは、１以上のギアを内蔵するギアボックス等によって実現される。回転方向変換部８４ｅは、駆動部８４ｄの駆動力を高摩擦回転部８４ａに伝達するための回転部を備え、この回転部と高摩擦回転部８４ａとを接触させた態様でカプセル型筐体２の内部に配置される。かかる回転方向変換部８４ｅは、駆動部８４ｄの駆動力の回転方向を高摩擦回転部８４ａの回転方向（図２１においては反時計回りの方向）に変換し、この方向変換した駆動力を高摩擦回転部８４ａに伝達する。すなわち、上述した高摩擦回転部８４ａは、かかる回転方向変換部８４ｅから伝達された駆動部８４ｄの駆動力によって回転する。   The rotation direction converter 84e is realized by a gear box or the like that incorporates one or more gears. The rotation direction conversion unit 84e includes a rotation unit for transmitting the driving force of the drive unit 84d to the high friction rotation unit 84a, and the capsule housing 2 is in a state in which the rotation unit and the high friction rotation unit 84a are in contact with each other. Placed inside. The rotation direction conversion unit 84e converts the rotation direction of the driving force of the driving unit 84d into the rotation direction of the high friction rotation unit 84a (counterclockwise direction in FIG. 21), and converts the direction converted driving force to the high friction. This is transmitted to the rotating part 84a. That is, the high friction rotating unit 84a described above is rotated by the driving force of the driving unit 84d transmitted from the rotation direction converting unit 84e.

このような構成を有する組織変形機構８４は、制御部８９の制御に基づいて駆動する駆動部８４ｄの駆動力によって、図２１に示すように互いに異なる方向に一対の高摩擦回転部８４ａ，８４ｂを回転させ、かかる高摩擦回転部８４ａ，８４ｂと接触した状態の体内部位（すなわち注射針８３を穿刺した状態の体内部位）の表面組織を変形（具体的には伸展）する。これによって、組織変形機構８４は、注射針８３を抜き取り後の体内部位の穿刺穴の開口径を最小化して、この穿刺穴を閉塞状態にする。   The tissue deformation mechanism 84 having such a configuration causes a pair of high friction rotating portions 84a and 84b to move in different directions as shown in FIG. 21 by the driving force of the driving portion 84d driven based on the control of the control portion 89. It is rotated to deform (specifically, extend) the surface tissue of the body part in contact with the high friction rotating parts 84a, 84b (that is, the body part punctured with the injection needle 83). As a result, the tissue deformation mechanism 84 minimizes the opening diameter of the puncture hole in the body part after extracting the injection needle 83, and puts the puncture hole in a closed state.

制御部８９は、注射針８３を穿刺した状態の体内部位の表面組織を伸展させるように組織変形機構８４を制御する。この場合、制御部８９は、駆動部８４ｄを駆動制御することによって、組織変形機構８４による体内部位の表面組織の伸展変形タイミングおよび伸展変形期間等を制御する。なお、制御部８９は、かかる組織変形機構８４の制御以外、上述した実施の形態１にかかるカプセル型医療装置１の制御部１３と同様の機能を有する。   The control unit 89 controls the tissue deformation mechanism 84 so as to extend the surface tissue of the body part in the state where the injection needle 83 is punctured. In this case, the control unit 89 controls the extension / deformation timing, the extension / deformation period, and the like of the surface tissue of the body part by the tissue deformation mechanism 84 by controlling the drive unit 84d. The control unit 89 has the same functions as those of the control unit 13 of the capsule medical device 1 according to the first embodiment other than the control of the tissue deformation mechanism 84.

つぎに、被検体内部における所望部位の一例である患部に薬液を注射する場合を例示して、本発明の実施の形態５にかかるカプセル型医療装置８１の動作を具体的に説明する。図２２は、注射針を穿刺した患部の表面組織を組織変形機構によって伸展させる状態を示す模式図である。図２３は、表面組織の伸展によって患部の穿刺穴が閉塞する状態を示す模式図である。以下では、図２２，２３を参照しつつ、注射針８３による患部１５の穿刺穴１６を閉塞状態にする際のカプセル型医療装置８１の動作を説明する。なお、この実施の形態５にかかるカプセル型医療装置８１の動作は、体内部位の穿刺穴を閉塞する際の動作以外、上述した実施の形態１にかかるカプセル型医療装置１と同様である。   Next, the operation of the capsule medical device 81 according to the fifth embodiment of the present invention will be specifically described by exemplifying a case where a drug solution is injected into an affected part, which is an example of a desired site inside the subject. FIG. 22 is a schematic view showing a state in which the surface tissue of the affected part punctured with the injection needle is extended by the tissue deformation mechanism. FIG. 23 is a schematic diagram showing a state where the puncture hole in the affected area is blocked by the extension of the surface tissue. Hereinafter, the operation of the capsule medical device 81 when the puncture hole 16 of the affected area 15 is closed by the injection needle 83 will be described with reference to FIGS. The operation of the capsule medical device 81 according to the fifth embodiment is the same as that of the capsule medical device 1 according to the first embodiment described above, except for the operation when closing the puncture hole in the body part.

患部１５に穿刺した注射針８３を介して患部１５の内部に薬液７を注入し終えたカプセル型医療装置８１において、制御部８９は、図２２に示すように、患部１５に注射針８３を穿刺した状態を維持するように駆動部６を制御しつつ、この注射針８３を穿刺した状態の患部１５の表面組織を伸展するように組織変形部８４を制御する。具体的には、制御部８９は、上述した駆動弁９を閉駆動させたタイミングに、駆動部８４ｄの駆動を開始させる。駆動部８４ｄは、かかる制御部８９の制御に基づいて高摩擦回転部８４ａ，８４ｂの回転力を生成する。高摩擦回転部８４ａ，８４ｂは、回転方向変換部８４ｅを介して伝達される駆動部８４ｄの駆動力によって、図２２に示すように互いに異なる方向に回転しつつ、注射針８３による患部１５の穿刺穴１６を中心に患部１５の表面組織（具体的には穿刺穴１６の近傍の表面組織）を伸展させる。   In the capsule medical device 81 in which the medicinal solution 7 has been injected into the affected area 15 via the injection needle 83 punctured in the affected area 15, the control unit 89 punctures the affected area 15 with the injection needle 83 as shown in FIG. The tissue deforming portion 84 is controlled so as to extend the surface tissue of the affected portion 15 in the state where the injection needle 83 is punctured while controlling the driving portion 6 so as to maintain the state. Specifically, the control unit 89 starts driving the drive unit 84d at the timing when the above-described drive valve 9 is driven to close. The drive unit 84d generates the rotational force of the high friction rotation units 84a and 84b based on the control of the control unit 89. The high friction rotating parts 84a and 84b puncture the affected part 15 with the injection needle 83 while rotating in different directions as shown in FIG. 22 by the driving force of the driving part 84d transmitted through the rotation direction changing part 84e. The surface tissue of the affected area 15 (specifically, the surface tissue in the vicinity of the puncture hole 16) is extended around the hole 16.

つぎに、制御部８９は、かかる高摩擦回転部８４ａ，８４ｂによる患部１５の表面組織の伸展状態を維持するように駆動部８４ｄを制御しつつ、この患部１５から注射針８３を抜き取ってカプセル型筐体２の内部に注射針８３を収納するように駆動部６を制御する。この場合、駆動部６は、かかる伸展状態の患部１５の穿刺穴１６から注射針８３を抜き取り、この注射針８３をカプセル型筐体２の内部に収納する。   Next, the control unit 89 controls the drive unit 84d so as to maintain the extended state of the surface tissue of the affected part 15 by the high friction rotating parts 84a and 84b, and pulls out the injection needle 83 from the affected part 15 to form a capsule type. The drive unit 6 is controlled so that the injection needle 83 is housed inside the housing 2. In this case, the drive unit 6 removes the injection needle 83 from the puncture hole 16 of the affected part 15 in the extended state, and stores the injection needle 83 in the capsule housing 2.

ここで、この注射針８３を抜き取られた患部１５は、上述したように組織変形機構８４の高摩擦回転部８４ａ，８４ｂによって穿刺穴１６近傍の表面組織を伸展した状態である。このため、かかる伸展状態の患部１５は、図２３に示すように、注射針８３の穿刺による穿刺穴１６の開口径を穿刺時に比して小径に縮小変形し、最終的に、この穿刺穴１６の開口径を最小化して穿刺穴１６を閉塞した状態（図２３に示す抜去後の状態）にする。   Here, the affected part 15 from which the injection needle 83 has been extracted is in a state in which the surface tissue in the vicinity of the puncture hole 16 is extended by the high friction rotating parts 84a and 84b of the tissue deformation mechanism 84 as described above. For this reason, as shown in FIG. 23, the affected part 15 in the stretched state is deformed by reducing the opening diameter of the puncture hole 16 by the puncture of the injection needle 83 to a smaller diameter compared to the time of puncture, and finally the puncture hole 16 The puncture hole 16 is closed (the state after the removal shown in FIG. 23) by minimizing the opening diameter.

制御部８９は、駆動部６の制御によって患部１６から注射針８３を抜き取った後も、高摩擦回転部８４ａ，８４ｂによる患部１５の表面組織の伸展状態を所定の時間維持するように駆動部８４ｄを制御し、カプセル型筐体２の内部に注射針８３を収納してから所定の時間が経過したタイミングに、この患部１５の表面組織の伸展動作を終了するように駆動部８４ｄを制御する。   After the injection needle 83 is removed from the affected part 16 under the control of the drive part 6, the control part 89 maintains a stretched state of the surface tissue of the affected part 15 by the high friction rotating parts 84a and 84b for a predetermined time. The drive unit 84d is controlled so that the extending operation of the surface tissue of the affected part 15 is terminated at a timing when a predetermined time has elapsed after the injection needle 83 is housed in the capsule-type housing 2.

ここで、かかる患部１５の穿刺穴（穿刺跡）１６は、上述したように組織変形機構８４が患部１５の表面組織の伸展状態を所定の時間維持していたので、この組織変形機構８４による伸展作用が解除された場合であっても閉塞状態を維持する。このため、患部１５は、注射針８３が抜き取られた後であっても、この穿刺穴１６から薬液７を漏出させることなく、内部に薬液７を留める。この結果、患部１５内部の薬液７は、この被検体内部における患部１５以外の体内部位に漏れ広がることがない。   Here, the puncture hole (puncture mark) 16 of the affected area 15 has been maintained by the tissue deformation mechanism 84 for a predetermined time because the tissue deformation mechanism 84 has maintained the extended state of the surface tissue of the affected area 15. Even when the action is released, the closed state is maintained. For this reason, even after the injection needle 83 is extracted, the affected part 15 keeps the drug solution 7 inside without causing the drug solution 7 to leak from the puncture hole 16. As a result, the medicinal solution 7 inside the affected part 15 does not leak and spread in the body part other than the affected part 15 inside the subject.

なお、かかるカプセル型医療装置８１において、制御部８９は、注射針８３を介して患部１５の内部に薬液７を注入し終えたタイミングに、高摩擦回転部８４ａ，８４ｂの回転によって患部１５の表面組織を伸展させるように駆動部８４ｄを制御していたが、組織変形機構８４による患部１５の表面組織の伸展変形タイミングは、これに限定されない。例えば、制御部８９は、患部１５に注射針８３を穿刺したタイミング（患部１５の内部に薬液７を注入する前）に、高摩擦回転部８４ａ，８４ｂの回転によって患部１５の表面組織を伸展させるように駆動部８４ｄを制御してもよい。または、制御部８９は、注射針８３を介して患部１５の内部に薬液７を注入している期間に、高摩擦回転部８４ａ，８４ｂの回転によって患部１５の表面組織を伸展させるように駆動部８４ｄを制御してもよい。   In the capsule medical device 81, the control unit 89 rotates the high friction rotating units 84a and 84b at the timing when the medicinal solution 7 has been injected into the affected unit 15 via the injection needle 83. Although the drive part 84d was controlled to extend the tissue, the extension / deformation timing of the surface tissue of the affected part 15 by the tissue deformation mechanism 84 is not limited to this. For example, the control unit 89 extends the surface tissue of the affected part 15 by the rotation of the high friction rotating parts 84a and 84b at the timing when the injection needle 83 is punctured into the affected part 15 (before the drug solution 7 is injected into the affected part 15). The drive unit 84d may be controlled as described above. Alternatively, the control unit 89 drives the drive unit so as to extend the surface tissue of the affected part 15 by the rotation of the high friction rotating parts 84a and 84b during the period when the drug solution 7 is injected into the affected part 15 through the injection needle 83. 84d may be controlled.

以上、説明したように、本発明の実施の形態５では、穿刺対象の体内部位の表面組織を伸展させる組織変形機構を備え、組織変形機構が、注射針を穿刺した状態の体内部位の表面組織（詳細には穿刺穴近傍の生体組織）を伸展させ、少なくとも体内部位から注射針を抜き取るまでの期間、この体内部位の表面組織の伸展状態を維持して、この体内部位の穿刺穴を閉塞状態にするようにし、その他を実施の形態１と同様に構成した。このため、上述した実施の形態１の場合と同様の作用効果を享受するとともに、注射針を縮小変形せずに体内部位の穿刺穴を閉塞状態にすることができ、これによって、被検体内部における複数の所望部位に薬液を注入することが可能なカプセル型医療装置を簡易な構成で実現することができる。   As described above, in the fifth embodiment of the present invention, a tissue deformation mechanism for extending the surface tissue of the body part to be punctured is provided, and the tissue deformation mechanism is a surface tissue of the body part in a state where the injection needle is punctured. (In detail, the living tissue near the puncture hole is extended, and the surface tissue of the internal body part is maintained in the extended state at least until the injection needle is removed from the internal body part. The other configuration is the same as that of the first embodiment. For this reason, while enjoying the effect similar to the case of Embodiment 1 mentioned above, the puncture hole of an in-vivo site | part can be made into an obstruct | occluded state, without carrying out reduction deformation of an injection needle, and, thereby, inside a subject. A capsule medical device capable of injecting a drug solution into a plurality of desired sites can be realized with a simple configuration.

なお、上述した実施の形態４の変形例２では、筒形状の焼灼部７４の内部に注射針５３を挿通し、この注射針５３の突出動作に同期して焼灼部７４をカプセル型筐体２から突出させていたが、これに限らず、カプセル型筐体２からの注射針５３の突出動作と焼灼部７４の突出動作とを同期して行わなくてもよい。この場合、実施の形態４の変形例２にかかるカプセル型医療装置７１において、焼灼部７４は、例えば図２４に示すように、注射針５３とは別体の状態でカプセル型筐体２の内部に配置され、この注射針５３とは独立した状態でカプセル型筐体２から突没可能なものであってもよい。図２４に示す焼灼部７４は、制御部７９の制御に基づく駆動部７６の作用によって、注射針５３の突没動作と異なるタイミングに開口部２ｃを通ってカプセル型筐体２から突没可能である。かかる焼灼部７４は、上述した筒形状の場合と同様に、注射針５３を穿刺した状態の体内部位における穿刺穴周囲の生体組織を焼灼処理して、この穿刺穴を閉塞状態にする。なお、この図２４に示す焼灼部７４は、開口部２ｃを通ってカプセル型筐体２から突没可能であれば、筒形状または棒形状（円柱状、角柱状）等の所望の形状のものであってもよい。   In the second modification of the above-described fourth embodiment, the injection needle 53 is inserted into the cylindrical cauterization part 74, and the cauterization part 74 is inserted into the capsule housing 2 in synchronization with the protruding operation of the injection needle 53. However, the present invention is not limited to this, and the protruding operation of the injection needle 53 from the capsule housing 2 and the protruding operation of the cauterizing unit 74 may not be performed in synchronization. In this case, in the capsule medical device 71 according to the second modification of the fourth embodiment, the cauterization unit 74 is separated from the injection needle 53 in the state of the capsule housing 2 as shown in FIG. It may be arranged so that it can protrude from the capsule housing 2 in a state independent of the injection needle 53. The cautery unit 74 shown in FIG. 24 can project and retract from the capsule housing 2 through the opening 2c at a timing different from the projecting and retracting operation of the injection needle 53 by the action of the driving unit 76 based on the control of the control unit 79. is there. In the same way as in the case of the cylindrical shape described above, the cauterization unit 74 cauterizes the living tissue around the puncture hole in the in-vivo region where the injection needle 53 is punctured, thereby closing the puncture hole. Note that the cautery portion 74 shown in FIG. 24 has a desired shape such as a cylindrical shape or a rod shape (columnar or prismatic shape) as long as it can project and retract from the capsule housing 2 through the opening 2c. It may be.

また、上述した実施の形態１では、熱可塑性の注射針３を加熱処理する加熱部４を薄膜状にして注射針３の外表面に巻き付ける態様で配置していたが、これに限らず、かかる注射針３を加熱処理する加熱部は、この注射針３の壁面に埋め込まれてもよいし、この注射針３の内壁面に配置されてもよい。また、かかる熱可塑性の注射針３は、加熱部４の加熱処理（すなわち電熱ヒータによる加熱処理）に限らず、加熱した薬液との接触によって軟化するように構成してもよい。あるいは、カプセル型筐体２の内部において注射針３をペルチェ素子等によって冷却し、体内部位に注射針３を穿刺した後、被検体の体温によって穿刺状態の注射針３を軟化させてもよい。   Moreover, in Embodiment 1 mentioned above, although the heating part 4 which heat-processes the thermoplastic injection needle 3 was arrange | positioned in the aspect wound around the outer surface of the injection needle 3 in a thin film form, it is not restricted to this. The heating unit that heat-processes the injection needle 3 may be embedded in the wall surface of the injection needle 3 or may be disposed on the inner wall surface of the injection needle 3. Further, the thermoplastic injection needle 3 is not limited to the heat treatment of the heating unit 4 (that is, the heat treatment by an electric heater), and may be configured to be softened by contact with a heated chemical solution. Alternatively, after the injection needle 3 is cooled by a Peltier element or the like inside the capsule-type housing 2 and the injection needle 3 is punctured into a body part, the punctured injection needle 3 may be softened by the body temperature of the subject.

さらに、上述した実施の形態２では、体内部位の穿刺穴を閉塞状態にする際、この体内部位の収縮力によって薄膜チューブ２４をフラット状に圧潰変形していたが、これに限らず、薄膜チューブ２４は、弾性部材によって形成され、弾性をもって縮径変形するものであってもよい。かかる弾性体である薄膜チューブ２４は、体内部位の穿刺穴を閉塞状態にする際、この体内部位の収縮力によって縮径変形し、この体内部位の穿刺穴から抜き取られた後に元の筒形状に復帰する。   Furthermore, in Embodiment 2 described above, when the puncture hole in the internal body part is closed, the thin film tube 24 is flattened and deformed by the contraction force of the internal body part. 24 may be formed of an elastic member, and may be elastically reduced in diameter and deformed. The thin-film tube 24, which is an elastic body, is deformed by a contraction force of the internal body part when the puncture hole in the internal body part is closed, and after being extracted from the puncture hole in the internal body part, Return.

また、上述した実施の形態１，２，４，５および実施の形態４の変形例１，２では、カプセル型筐体２の径方向に注射針を突没動作させ、体内部位の表面に対して略垂直な態様で体内部位に注射針を穿刺していたが、これに限らず、上述した実施の形態３およびその変形例１に例示されるように、カプセル型筐体２の径方向に対して注射針の長手方向が斜めになる態様でカプセル型筐体２から注射針を突没動作させ、体内部位の表面に対して鋭角をなした態様で体内部位に注射針を穿刺してもよい。この場合も、上述した実施の形態３およびその変形例１と同様に、注射針による体内部位の穿刺穴の長さを、体内部位に対して垂直に注射針を穿刺した場合に比して長くすることができ、この結果、穿刺穴からの薬液漏出の防止効果を一層高めることができる。   In the first, second, fourth, and fifth embodiments and the first and second modifications of the fourth embodiment, the injection needle is caused to project and retract in the radial direction of the capsule-type housing 2 to the surface of the body part. However, the present invention is not limited to this, and as illustrated in the third embodiment and the first modification thereof, the capsule needle 2 is arranged in the radial direction. On the other hand, even if the injection needle is protruded and retracted from the capsule-type housing 2 in a mode in which the longitudinal direction of the injection needle is oblique, the injection needle is punctured into the internal body part in an aspect that forms an acute angle with the surface of the internal body part Good. Also in this case, the length of the puncture hole in the body part by the injection needle is longer than that in the case where the needle is punctured perpendicularly to the body part, as in the third embodiment and the modification example 1 described above. As a result, the effect of preventing leakage of the chemical liquid from the puncture hole can be further enhanced.

さらに、上述した実施の形態３では、カプセル型筐体２の径方向に対して注射針の長手方向が斜めになる態様でカプセル型筐体２から注射針を突没動作させ、体内部位の表面に対して鋭角をなした態様で体内部位に注射針を穿刺していたが、これに限らず、上述した実施の形態１，２，４，５および実施の形態４の変形例１，２に例示されるように、カプセル型筐体２の径方向に注射針を突没動作させ、体内部位の表面に対して略垂直な態様で体内部位に注射針を穿刺してもよい。   Furthermore, in the above-described third embodiment, the injection needle is caused to project and retract from the capsule-type housing 2 in such a manner that the longitudinal direction of the injection needle is inclined with respect to the radial direction of the capsule-type housing 2, and the surface of the body part However, the present invention is not limited to this, and the first, second, fourth, and fifth embodiments described above and the first and second modifications of the fourth embodiment are not limited thereto. As illustrated, the injection needle may be protruded and retracted in the radial direction of the capsule housing 2 and the injection needle may be punctured in the body part in a manner substantially perpendicular to the surface of the body part.

また、上述した実施の形態４およびその変形例２では、焼灼部による穿刺穴周囲の生体組織の焼灼処理が完了した後に注射針を体内部位から抜き取っていたが、これに限らず、体内部位に穿刺した状態の注射針は、焼灼部によってこの体内部位の穿刺穴周囲の生体組織が焼灼処理されている期間に徐々に抜き取られてもよい。すなわち、上述した実施の形態４およびその変形例２では、焼灼部による体内部位の焼灼処理と体内部位からの注射針の抜取動作とを同時に実行し、焼灼部によって穿刺穴周囲の生体組織を焼灼処理しつつ、この穿刺穴から注射針を徐々に抜き取ってもよい。   In Embodiment 4 and Modification 2 described above, the injection needle is extracted from the body part after the cauterization process of the living tissue around the puncture hole by the cautery unit is completed. The injection needle in the punctured state may be gradually extracted during a period in which the living tissue around the puncture hole in the body part is cauterized by the cautery unit. That is, in the above-described Embodiment 4 and Modification 2 thereof, the cauterization process of the internal body part by the cauterization part and the extraction operation of the injection needle from the internal body part are simultaneously performed, and the living tissue around the puncture hole is cauterized by the cauterization part. The syringe needle may be gradually removed from the puncture hole while processing.

さらに、上述した実施の形態４の変形例１では、焼灼処理機能を有する注射針６３を、穿刺穴周囲の生体組織の焼灼処理が完了した後に体内部位から抜き取っていたが、これに限らず、かかる注射針６３は、体内部位の穿刺穴周囲の生体組織を焼灼処理しつつ、この体内部位から徐々に抜き取られてもよい。この場合、かかる注射針６３は、この体内部位から完全に抜き取られるまでに穿刺穴周囲の生体組織の焼灼処理を完了すればよい。   Furthermore, in the first modification of the fourth embodiment described above, the injection needle 63 having a cauterization function is extracted from the body part after the cauterization process of the living tissue around the puncture hole is completed. The injection needle 63 may be gradually extracted from the internal body part while cauterizing the living tissue around the puncture hole in the internal body part. In this case, it is only necessary to complete the cauterization process of the living tissue around the puncture hole until the injection needle 63 is completely extracted from the body part.

また、上述した実施の形態５では、注射針８３を穿刺した状態の体内部位の表面組織を組織変形機構８４によって伸展状態にしていたが、これに限らず、組織変形機構８４は、注射針８３を穿刺する前の体内部位を伸展状態にしてもよい。この場合、上述したカプセル型医療装置８１は、組織変形機構８４によって表面組織を伸展した状態の体内部位に注射針８３を穿刺し、その後、この体内部位から注射針８３を抜き取った後に組織変形機構８４の伸展動作を終了する。この場合も、伸展状態であった体内部位の収縮力によって注射針８３による穿刺穴を閉塞状態にすることができる。   In the above-described fifth embodiment, the surface tissue of the body part in the state where the injection needle 83 has been punctured is extended by the tissue deformation mechanism 84. However, the present invention is not limited to this. The body part before puncture may be in an extended state. In this case, the capsule-type medical device 81 described above punctures the injection needle 83 into a body part in a state where the surface tissue is extended by the tissue deformation mechanism 84, and then removes the injection needle 83 from the body part, and then the tissue deformation mechanism. The extension operation 84 is finished. Also in this case, the puncture hole by the injection needle 83 can be closed by the contraction force of the body part that was in the extended state.

さらに、上述した実施の形態５では、注射針８３を穿刺した状態の体内部位の表面組織を組織変形機構８４によって伸展状態にしていたが、これに限らず、組織変形機構８４は、注射針８３を穿刺した体内部位の表面組織を穿刺穴側に寄せて、この表面組織を縮めた状態にしてもよい。この場合、上述した組織変形機構８４の駆動部８４ｄを逆回転させて、高摩擦回転部８４ａ，８４ｂを各々逆回転させればよい。この場合も、かかる組織変形機構８４の組織変形作用によって注射針８３による穿刺穴を閉塞状態にすることができる。なお、かかる組織変形機構８４が体内部位の表面組織を縮めるタイミングは、体内部位から注射針８３が完全に抜き取られるまでの期間であってもよいし、体内部位から注射針８３が完全に抜き取られた後であってもよい。   Furthermore, in the fifth embodiment described above, the surface tissue of the body part in the state where the injection needle 83 has been punctured is extended by the tissue deformation mechanism 84, but this is not limiting, and the tissue deformation mechanism 84 is not limited to the injection needle 83. Alternatively, the surface tissue of the body part that has been punctured may be brought closer to the puncture hole and the surface tissue may be contracted. In this case, the drive unit 84d of the tissue deformation mechanism 84 described above may be rotated in the reverse direction, and the high friction rotating units 84a and 84b may be rotated in the reverse direction. Also in this case, the puncture hole by the injection needle 83 can be closed by the tissue deformation action of the tissue deformation mechanism 84. The timing at which the tissue deformation mechanism 84 contracts the surface tissue of the internal body part may be a period until the injection needle 83 is completely extracted from the internal body part, or the injection needle 83 is completely extracted from the internal body part. It may be after.

また、上述した実施の形態１〜５および各変形例では、被検体の体内部位に作用させる薬液を注射するカプセル型医療装置を例示していたが、これに限らず、被検体の体内部位に所望の液体を注射するカプセル型医療装置であってもよい。この場合、かかるカプセル型医療装置によって体内部位に注射される液体は、無色透明の液体であってもよいし、着色された有色の液体（例えばマーキング用の液体）であってもよい。   Moreover, in Embodiment 1-5 mentioned above and each modification, although the capsule type medical device which inject | pours the chemical | medical solution made to act on the in-vivo site | part of a test object was illustrated, it is not restricted to this, In-vivo site | part of a test object It may be a capsule medical device that injects a desired liquid. In this case, the liquid injected into the body part by the capsule medical device may be a colorless and transparent liquid or a colored liquid (for example, a marking liquid).

さらに、上述した実施の形態１〜５および各変形例では、電力によって駆動する単一の駆動部が、カプセル型筐体から注射針を突没して、被検体の体内部位に注射針を穿刺し、この穿刺した注射針を体内部位から抜き取っていたが、これに限らず、カプセル型筐体から注射針を突没する駆動部と、体内部位に対する注射針の穿刺および抜取を行う駆動部とを別のものとしてもよい。この場合、カプセル型筐体から注射針を突没する駆動部は、上述した駆動部６に例示されるように電力によって駆動する電動アクチュエータ等であってもよいし、外部から印加される外部磁界の作用によって駆動する磁気アクチュエータであってもよい。また、注射針の穿刺および抜取を行う駆動部は、電力によって駆動する電動アクチュエータ等であってもよいし、外部磁界に追従して駆動する磁石であってもよい。   Furthermore, in the first to fifth embodiments and the modifications described above, the single drive unit that is driven by electric power projects the injection needle from the capsule-type housing and punctures the injection needle into the body part of the subject. However, the present invention is not limited to this, and the drive unit that projects and retracts the injection needle from the capsule-type housing, and the drive unit that punctures and removes the injection needle from the internal site May be different. In this case, the drive unit that protrudes and retracts the injection needle from the capsule housing may be an electric actuator that is driven by electric power as exemplified by the drive unit 6 described above, or an external magnetic field applied from the outside. It may be a magnetic actuator driven by the action. Further, the drive unit that performs puncture and extraction of the injection needle may be an electric actuator that is driven by electric power, or may be a magnet that is driven following an external magnetic field.

具体的には、上述した実施の形態１にかかるカプセル型医療装置１は、注射針３の突没動作を行う駆動部６と、注射針３の穿刺動作および抜取動作を行う駆動部（駆動部６と異なる別の駆動部）とを内蔵してもよい。図２５は、注射針の突没動作の駆動部と注射針の穿刺動作および抜取動作の駆動部とを備えたカプセル型医療装置の一構成例を示す模式図である。   Specifically, the capsule medical device 1 according to the first embodiment described above includes a drive unit 6 that performs the projecting and retracting operation of the injection needle 3, and a drive unit that performs the puncture operation and the extraction operation of the injection needle 3 (drive unit). 6 may be incorporated. FIG. 25 is a schematic diagram illustrating a configuration example of a capsule medical device including a drive unit for the projecting and retracting operation of the injection needle and a drive unit for the puncturing operation and the extraction operation of the injection needle.

図２５に示すカプセル型医療装置１において、注射針３は、駆動部６の駆動方向（図２５の太線矢印によって示される注射針３の突没方向）に対して傾斜するように支持部５によって支持される。駆動部６は、制御部１３の制御に基づいて駆動して、カプセル型筐体２から注射針３を突没する。磁石９０は、カプセル型筐体２の径方向と磁化方向とを一致させる態様でカプセル型筐体２の内部に配置される。かかる磁石９０は、被検体外部の外部装置によって印加された外部磁界に追従してカプセル型筐体２を回転駆動し、これによって、突出状態の注射針３を体内部位に穿刺し、その後、この穿刺した注射針３を体内部位から抜き取る。   In the capsule medical device 1 shown in FIG. 25, the injection needle 3 is supported by the support portion 5 so as to be inclined with respect to the drive direction of the drive portion 6 (the protruding and retracting direction of the injection needle 3 indicated by the thick arrow in FIG. 25). Supported. The drive unit 6 is driven based on the control of the control unit 13 to project and retract the injection needle 3 from the capsule housing 2. The magnet 90 is disposed inside the capsule casing 2 in such a manner that the radial direction of the capsule casing 2 matches the magnetization direction. The magnet 90 follows the external magnetic field applied by the external device outside the subject to rotationally drive the capsule housing 2, thereby puncturing the protruding injection needle 3 into the body part, and then The punctured injection needle 3 is extracted from the body part.

具体的には、図２６に示すように、磁石９０は、外部磁界に追従してカプセル型筐体２を周方向に回転駆動するとともに、このカプセル型筐体２から突出した状態の注射針３を体内部位（例えば患部１５）に向けて回転駆動し、これによって、加熱部４とともに注射針３を患部１５に穿刺する。その後、磁石９０は、上述した実施の形態１における注射針３の抜取タイミングと同様のタイミングにおいて、外部から印加された外部磁界に追従してカプセル型筐体２を周方向（穿刺の場合と逆方向）に回転駆動するとともに、この患部１５から離間する方向に縮小変形後の注射針３を回転駆動し、これによって、この患部１５から加熱部４とともに縮小変形後の注射針３を抜き取る。その後、上述した駆動部６は、この縮小変形後の注射針３と加熱部４とをカプセル型筐体２の内部に収納する。また、前記外部磁界によって注射針３が患部１５に穿刺された後、カプセル型医療装置１の回転方向の位置が穿刺された状態で静止するように静磁界を印加してもよい。この状態で患部１５の内部への薬液７の注入と、その後の加熱部４による注射針３の縮小変形とをすることで、患部１５付近の反力による注射針３の抜けを防止し、より確実に薬液７を注射することができる。   Specifically, as shown in FIG. 26, the magnet 90 follows the external magnetic field to rotationally drive the capsule casing 2 in the circumferential direction, and the injection needle 3 in a state of protruding from the capsule casing 2. Is rotated toward the body part (for example, the affected part 15), whereby the injection needle 3 is punctured into the affected part 15 together with the heating part 4. Thereafter, the magnet 90 follows the external magnetic field applied from the outside at the same timing as the extraction timing of the injection needle 3 in the first embodiment described above, and moves the capsule housing 2 in the circumferential direction (opposite to the case of puncture). The injection needle 3 after being reduced and deformed is driven to rotate in a direction away from the affected area 15, whereby the injection needle 3 after being reduced and deformed is extracted from the affected area 15 together with the heating part 4. Thereafter, the drive unit 6 described above houses the injection needle 3 and the heating unit 4 after the reduction deformation in the capsule housing 2. In addition, after the injection needle 3 is punctured into the affected part 15 by the external magnetic field, a static magnetic field may be applied so that the capsule medical device 1 is stationary with the position in the rotational direction being punctured. In this state, the injection of the medicinal solution 7 into the affected part 15 and the subsequent deformation of the injection needle 3 by the heating part 4 prevent the needle 3 from coming off due to the reaction force near the affected part 15. The chemical solution 7 can be reliably injected.

このように、図２５に示すカプセル型医療装置１は、上述した実施の形態１の場合と同様に、カプセル型筐体２から注射針３を突没させて、体内部位に注射針３を穿刺し、この穿刺した注射針３を体内部位から抜き取ることができ、上述した実施の形態１の場合と同様の作用効果を享受する。なお、図２５に示したような注射針の突没動作を行う駆動部と注射針の穿刺動作および抜取動作を行う駆動部とを内蔵する構成は、実施の形態１にかかるカプセル型医療装置１に限らず、上述した実施の形態２〜５および各変形例のいずれかにかかるカプセル型医療装置に適用してもよい。この場合も、上述した実施の形態２〜５および各変形例のいずれかと同様の作用効果を享受するカプセル型医療装置を構成することができる。   As described above, in the capsule medical device 1 shown in FIG. 25, as in the case of the first embodiment described above, the injection needle 3 is protruded and subtracted from the capsule-type housing 2, and the injection needle 3 is punctured into a body part. Then, the punctured injection needle 3 can be extracted from the body part, and the same operation and effect as in the case of the first embodiment described above can be enjoyed. In addition, the structure which incorporates the drive part which performs the protrusion / retraction operation | movement of an injection needle as shown in FIG. 25, and the drive part which performs the puncture operation | movement and extraction operation | movement of an injection needle is the capsule type medical device 1 concerning Embodiment 1. FIG. However, the present invention may be applied to the capsule medical device according to any of Embodiments 2 to 5 and each of the modifications described above. Also in this case, it is possible to configure a capsule medical device that enjoys the same functions and effects as those of any of the above-described Embodiments 2 to 5 and the modifications.

本発明の実施の形態１にかかるカプセル型医療装置の一構成例を示す模式図である。It is a schematic diagram which shows one structural example of the capsule type medical device concerning Embodiment 1 of this invention. 被検体内部のカプセル型医療装置が患部に到達する状態を示す模式図である。It is a schematic diagram which shows the state which the capsule type medical device inside a subject reaches | attains an affected part. 被検体内部のカプセル型医療装置が患部に薬液を注射する状態を示す模式図である。It is a schematic diagram which shows the state which the capsule type medical device inside a subject inject | pours a chemical | medical solution into an affected part. 注射針の縮小変形によって体内部位の穿刺穴が閉塞する状態を示す模式図である。It is a schematic diagram which shows the state which the puncture hole of an internal-body site | part obstruct | occludes by shrinking deformation of an injection needle. 縮小変形した注射針がカプセル型筐体の内部に収納される状態を示す模式図である。It is a schematic diagram which shows the state by which the injection needle reduced and deform | transformed is accommodated in the inside of a capsule type | mold housing | casing. 本発明の実施の形態２にかかるカプセル型医療装置の一構成例を示す模式図である。It is a schematic diagram which shows one structural example of the capsule type medical device concerning Embodiment 2 of this invention. 被検体内部のカプセル型医療装置が薄膜チューブとともに注射針を患部に穿刺する状態を示す模式図である。It is a schematic diagram which shows the state which the capsule type medical device inside a subject punctures an affected part with an injection needle with a thin film tube. 薄膜チューブの縮小変形によって体内部位の穿刺穴が閉塞する状態を示す模式図である。It is a schematic diagram which shows the state which the puncture hole of an internal-body site | part obstruct | occludes by shrinking deformation of a thin film tube. 薄膜チューブがカプセル型筐体の内部に収納される状態を示す模式図である。It is a schematic diagram which shows the state in which a thin film tube is accommodated in the inside of a capsule type housing. 本発明の実施の形態３にかかるカプセル型医療装置の一構成例を示す模式図である。It is a schematic diagram which shows one structural example of the capsule type medical device concerning Embodiment 3 of this invention. 本発明の実施の形態３にかかるカプセル型医療装置が体内部位に注射する際の一連の処理手順を例示するフローチャートである。It is a flowchart which illustrates a series of processing procedures at the time of the capsule type medical device concerning Embodiment 3 of this invention inject | pouring into a site | part in a body. 低速の抜取速度で患部から注射針を抜き取りつつ穿刺穴を閉塞する状態を示す模式図である。It is a schematic diagram which shows the state which obstruct | occludes a puncture hole, extracting an injection needle from an affected part with a low extraction speed. 本発明の実施の形態３の変形例１にかかるカプセル型医療装置の一構成例を示す模式図である。It is a schematic diagram which shows one structural example of the capsule type medical device concerning the modification 1 of Embodiment 3 of this invention. 本発明の実施の形態３の変形例１にかかるカプセル型医療装置が体内部位に注射する際の一連の処理手順を例示するフローチャートである。It is a flowchart which illustrates a series of processing procedures at the time of the capsule medical device concerning the modification 1 of Embodiment 3 of this invention inject | pouring into a body part. カプセル型筐体側に先端開口部を向けた状態の注射針を低速の抜取速度で患部から抜き取りつつ穿刺穴を閉塞する状態を示す模式図である。It is a schematic diagram which shows the state which obstruct | occludes a puncture hole, extracting the injection needle in the state which orient | assigned the front-end | tip opening part to the capsule-type housing | casing from an affected part at low extraction speed. 本発明の実施の形態４にかかるカプセル型医療装置の一構成例を示す模式図である。It is a schematic diagram which shows one structural example of the capsule type medical device concerning Embodiment 4 of this invention. 注射針周囲の生体組織の焼灼処理によって体内部位の穿刺穴が閉塞する状態を示す模式図である。It is a schematic diagram which shows the state in which the puncture hole of a body part is obstruct | occluded by the cauterization process of the biological tissue around an injection needle. 本発明の実施の形態４の変形例１にかかるカプセル型医療装置の一構成例を示す模式図である。It is a schematic diagram which shows one structural example of the capsule type medical device concerning the modification 1 of Embodiment 4 of this invention. 本発明の実施の形態４の変形例２にかかるカプセル型医療装置の一構成例を示す模式図である。It is a schematic diagram which shows one structural example of the capsule type medical device concerning the modification 2 of Embodiment 4 of this invention. 注射針周囲の生体組織の焼灼処理によって体内部位の穿刺穴が閉塞する状態を示す模式図である。It is a schematic diagram which shows the state in which the puncture hole of a body part is obstruct | occluded by the cauterization process of the biological tissue around an injection needle. 本発明の実施の形態５にかかるカプセル型医療装置の一構成例を示す模式図である。It is a schematic diagram which shows one structural example of the capsule type medical device concerning Embodiment 5 of this invention. 注射針を穿刺した患部の表面組織を組織変形機構によって伸展させる状態を示す模式図である。It is a schematic diagram which shows the state which extends the surface tissue of the affected part which punctured the injection needle with a tissue deformation | transformation mechanism. 表面組織の伸展によって患部の穿刺穴が閉塞する状態を示す模式図である。It is a schematic diagram which shows the state which the puncture hole of an affected part obstruct | occludes by extension of surface tissue. 本発明の実施の形態４の変形例２にかかるカプセル型医療装置の別態様を示す模式図である。It is a schematic diagram which shows another aspect of the capsule type medical device concerning the modification 2 of Embodiment 4 of this invention. 注射針の突没動作の駆動部と注射針の穿刺動作および抜取動作の駆動部とを備えたカプセル型医療装置の一構成例を示す模式図である。It is a schematic diagram showing an example of the configuration of a capsule medical device including a drive unit for a projecting and retracting operation of an injection needle and a drive unit for a puncturing operation and an extraction operation of an injection needle. 外部磁界の作用によって体内部位に注射針を穿刺する状態を例示する模式図である。It is a schematic diagram which illustrates the state which punctures an injection needle to the internal region site | part by the effect | action of an external magnetic field.

符号の説明Explanation of symbols

１，２１，３１，４１，５１，６１，７１，８１ カプセル型医療装置
２ カプセル型筐体
２ａ 筒状筐体
２ｂ ドーム形状筐体
２ｃ 開口部
３，２３，３３，５３，６３，８３ 注射針
４ 加熱部
５，２５，３５，７５ 支持部
６，２６，３６，７６，８４ｄ 駆動部
７ 薬液
８ 吐出バルーン
９ 駆動弁
１０ａ 連通管
１０ｂ チューブ
１１ 撮像部
１１ａ 照明部
１１ｂ 光学系
１１ｃ 固体撮像素子
１２ 通信部
１３，２９，３９，４９，５９，７９，８９ 制御部
１３ａ 画像処理部
１４ 電源部
１５ 患部
１６ 穿刺穴
１７ 生体組織
２４ 薄膜チューブ
４６ 回転駆動部
５４，７４ 焼灼部
８４ 組織変形機構
８４ａ，８４ｂ 高摩擦回転部
８４ｃ 回転伝達部
８４ｅ 回転方向変換部
９０ 磁石
ＣＬ 中心軸 1, 21, 31, 41, 51, 61, 71, 81 Capsule medical device 2 Capsule housing 2a Tubular housing 2b Dome housing 2c Opening 3, 23, 33, 53, 63, 83 Injection needle 4 Heating unit 5, 25, 35, 75 Support unit 6, 26, 36, 76, 84d Drive unit 7 Chemical solution 8 Discharge balloon 9 Drive valve 10a Communication tube 10b Tube 11 Imaging unit 11a Illumination unit 11b Optical system 11c Solid-state imaging device 12 Communication part 13, 29, 39, 49, 59, 79, 89 Control part 13a Image processing part 14 Power supply part 15 Affected part 16 Puncture hole 17 Biological tissue 24 Thin film tube 46 Rotation drive part 54, 74 Ablation part 84 Tissue deformation mechanism 84a, 84b High friction rotation part 84c Rotation transmission part 84e Rotation direction conversion part 90 Magnet CL Center axis

Claims (15)

被検体の体内部位に注射針を穿刺し、この穿刺した前記注射針を前記体内部位から抜き取る針駆動手段と、
前記体内部位に穿刺した前記注射針を介して前記体内部位の内部に液体を注入する液体注入手段と、
前記液体注入手段が前記体内部位の内部に前記液体を注入してから前記針駆動手段が前記体内部位から前記注射針を抜き取るまでの期間に、前記注射針による前記体内部位の穿刺穴を閉塞状態にする閉塞手段と、
を備えたことを特徴とするカプセル型医療装置。 Needle drive means for puncturing an injection needle into a body part of a subject and extracting the punctured injection needle from the body part;
A liquid injection means for injecting a liquid into the internal body part via the injection needle punctured into the internal body part;
In the period from when the liquid injection means injects the liquid into the body part until the needle driving means pulls out the injection needle from the body part, the puncture hole of the body part is closed by the injection needle Occlusion means to
A capsule-type medical device comprising: 前記閉塞手段は、前記注射針の外径を変化させる針径変化手段であることを特徴とする請求項１に記載のカプセル型医療装置。   The capsule medical device according to claim 1, wherein the closing means is needle diameter changing means for changing an outer diameter of the injection needle. 前記針径変化手段は、前記注射針を加熱処理によって縮小変形させて前記穿刺穴を閉塞状態にする加熱手段であり、
前記注射針は、熱可塑性樹脂によって形成され、前記体内部位に穿刺した状態で前記加熱手段によって加熱処理された場合、前記体内部位の収縮力によって縮小変形することを特徴とする請求項２に記載のカプセル型医療装置。 The needle diameter changing means is a heating means that shrinks and deforms the injection needle by a heat treatment to close the puncture hole,
The said injection needle is formed with a thermoplastic resin, and when it heat-processes by the said heating means in the state punctured to the said internal-body site | part, it shrinks and deform | transforms with the contraction force of the said internal-body site | part. Capsule medical device. 前記閉塞手段は、
前記注射針に摺動可能に外嵌し、前記体内部位に穿刺する前記注射針とともに前記穿刺穴に入る軟質管と、
前記体内部位に向けて前記注射針とともに前記軟質管を突出させ、前記針駆動手段が前記体内部位から前記注射針を抜き取るまでの期間、前記穿刺穴に前記軟質管を留め、前記注射針の抜き取り後に前記体内部位から前記軟質管を抜き取って、前記カプセル型筐体の内部に前記軟質管を収納する管駆動手段と、
を備え、
前記軟質管は、前記注射針に外嵌した状態で管形状を維持し、前記針駆動手段によって前記体内部位から前記注射針が抜き取られるとともに前記体内部位の収縮力によって縮小変形して、前記穿刺穴を閉塞状態にすることを特徴とする請求項１に記載のカプセル型医療装置。 The closing means is
A soft tube that slidably fits on the injection needle and enters the puncture hole together with the injection needle that punctures the body part;
The soft tube is projected together with the injection needle toward the internal body part, and the soft tube is fastened to the puncture hole for a period until the needle driving means extracts the injection needle from the internal body part, and the injection needle is removed. Tube drive means for later extracting the soft tube from the body part and storing the soft tube in the capsule-type housing;
With
The soft tube maintains a tube shape in a state of being externally fitted to the injection needle, and the needle drive unit removes the injection needle from the body part and is contracted and deformed by the contraction force of the body part. The capsule medical device according to claim 1, wherein the hole is closed. 前記閉塞手段は、前記体内部位の収縮速度に比して低い速度で前記体内部位から前記注射針を抜き取るように前記針駆動手段を制御する制御手段を備えたことを特徴とする請求項１に記載のカプセル型医療装置。   2. The control device according to claim 1, wherein the occlusion means includes control means for controlling the needle driving means so that the injection needle is withdrawn from the body part at a lower speed than a contraction speed of the body part. The capsule medical device as described. 前記閉塞手段は、前記注射針の長手軸回りに前記注射針を回転する回転駆動手段をさらに備え、
前記制御手段は、前記体内部位に前記注射針を穿刺する場合、前記注射針の先端開口部が前記体内部位側に向くように前記回転駆動手段を制御し、前記体内部位から前記注射針を抜き取る場合、前記先端開口部の方向が反転する態様に前記注射針を回転するように前記回転駆動手段を制御することを特徴とする請求項５に記載のカプセル型医療装置。 The closing means further comprises a rotation driving means for rotating the injection needle around the longitudinal axis of the injection needle,
When the injection needle is punctured into the body part, the control means controls the rotation driving means so that the distal end opening of the injection needle faces the body part side, and extracts the injection needle from the body part. 6. The capsule medical device according to claim 5, wherein the rotation driving unit is controlled so as to rotate the injection needle so that the direction of the tip opening is reversed. 前記閉塞手段は、前記注射針の周囲の生体組織を焼灼して前記穿刺穴を閉塞状態にする焼灼手段であることを特徴とする請求項１に記載のカプセル型医療装置。   The capsule medical device according to claim 1, wherein the closing means is a cauterizing means for cauterizing a living tissue around the injection needle and closing the puncture hole. 前記焼灼手段は、前記カプセル型筐体の外壁部であって前記注射針の突没口の近傍に配置されることを特徴とする請求項７に記載のカプセル型医療装置。   The capsule-type medical device according to claim 7, wherein the cauterizing means is disposed on an outer wall portion of the capsule-type housing and in the vicinity of a projecting / recessing opening of the injection needle. 前記焼灼手段は、前記注射針であることを特徴とする請求項７に記載のカプセル型医療装置。   The capsule medical device according to claim 7, wherein the cauterizing unit is the injection needle. 前記カプセル型筐体から前記焼灼手段を突没させて、前記注射針の近傍であって前記体内部位の表面に前記焼灼手段を接触させ、前記穿刺穴を閉塞状態にした後、前記カプセル型筐体の内部に前記焼灼手段を収納する焼灼部駆動手段を備え、
前記焼灼手段は、前記注射針を内部に挿通可能な管形状に形成され、
前記注射針は、前記焼灼手段の内部を通って突没することを特徴とする請求項７に記載のカプセル型医療装置。 After the cauterizing means is protruded and retracted from the capsule-type casing, the cauterizing means is brought into contact with the surface of the body part in the vicinity of the injection needle, and the puncture hole is closed, and then the capsule-type casing is closed. A cautery unit driving means for storing the cauterizing means inside the body,
The cauterization means is formed in a tube shape through which the injection needle can be inserted,
The capsule medical device according to claim 7, wherein the injection needle projects and sinks through the inside of the cauterizing means. 前記閉塞手段は、前記注射針を穿刺する前記体内部位の表面を変形させて前記穿刺穴を閉塞状態にすることを特徴とする請求項１に記載のカプセル型医療装置。   The capsule medical device according to claim 1, wherein the occluding means deforms a surface of the body part that punctures the injection needle to close the puncture hole. 前記閉塞手段は、前記体内部位に穿刺した状態の前記注射針の近傍の生体組織を伸展して前記穿刺穴を閉塞状態にする組織伸展機構であることを特徴とする請求項１１に記載のカプセル型医療装置。   12. The capsule according to claim 11, wherein the closing means is a tissue extension mechanism that extends a living tissue in the vicinity of the injection needle in a state of being punctured into the body part to close the puncture hole. Type medical device. 前記針駆動手段は、前記体内部位の表面と前記注射針とのなす角度を９０度より小さくした態様で前記体内部位に前記注射針を穿刺することを特徴とする請求項１〜１２のいずれか一つに記載のカプセル型医療装置。   The needle driving means punctures the injection needle into the internal body part in an aspect in which an angle formed between the surface of the internal body part and the injection needle is smaller than 90 degrees. The capsule medical device according to one. 前記針駆動手段は、当該カプセル型医療装置のカプセル型筐体から前記注射針を突没させて、前記被検体の体内部位に前記注射針を穿刺し、この穿刺した前記注射針を前記体内部位から抜き取って、前記カプセル型筐体の内部に前記注射針を収納することを特徴とする請求項１〜１３のいずれか一つに記載のカプセル型医療装置。   The needle driving means projects and injects the injection needle from the capsule-type housing of the capsule-type medical device, punctures the injection needle into the body part of the subject, and inserts the punctured injection needle into the body part. The capsule medical device according to claim 1, wherein the injection needle is extracted from the capsule housing and accommodated in the capsule housing. 当該カプセル型医療装置のカプセル型筐体から前記注射針を突没させる突没駆動手段を備え、
前記針駆動手段は、外部磁界に追従して回転駆動して、前記突没駆動手段によって突出した前記注射針を前記被検体の体内部位に穿刺し、この穿刺した前記注射針を前記体内部位から抜き取る磁石であることを特徴とする請求項１〜１３のいずれか一つに記載のカプセル型医療装置。 A projecting and retracting drive means for projecting and retracting the injection needle from the capsule housing of the capsule medical device;
The needle driving means is driven to rotate following an external magnetic field, punctures the injection needle protruded by the protrusion / retraction driving means into the body part of the subject, and the punctured injection needle is removed from the body part. The capsule medical device according to claim 1, wherein the capsule medical device is a magnet to be extracted.
JP2008147321A 2008-06-04 2008-06-04 Capsule medical device Expired - Fee Related JP5203050B2 (en)

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