JP2005348755A - Ophthalmologic measuring device - Google Patents

Ophthalmologic measuring device Download PDF

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JP2005348755A
JP2005348755A JP2004169321A JP2004169321A JP2005348755A JP 2005348755 A JP2005348755 A JP 2005348755A JP 2004169321 A JP2004169321 A JP 2004169321A JP 2004169321 A JP2004169321 A JP 2004169321A JP 2005348755 A JP2005348755 A JP 2005348755A
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light
eye
examined
optical system
refractive power
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JP4619694B2 (en
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Masaaki Hanebuchi
昌明 羽根渕
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Nidek Co Ltd
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Nidek Co Ltd
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Abstract

<P>PROBLEM TO BE SOLVED: To provide an ophthalmologic measuring device capable of measuring/obtaining various biological information by one unit. <P>SOLUTION: The ophthalmologic measuring device measures the refractive power and the length of ocular axis of an examined eye non-contact. The ophthalmologic measuring device comprises a measuring light irradiation optical system for applying the light with low coherent length to the examined eye, a light receiving optical system for receiving the reflection light from the fundus oculi of the examined eye by the light with low coherent length applied to the examined eye, a refractive power measuring means for finding the refractive power of the examined eye based on the state of receiving the reflection light received by the light receiving optical system, a reference light irradiation optical system for making the reflection light from the anterior ocular segment of the examined eye obtained by the irradiation of the light with low coherent length the reference light, an interference optical system for synthesizing the reference light obtained by the reference light irradiation optical system and the reflection light from the fundus oculi obtained by the measuring light irradiation optical system to interfere, and dispersing the obtained interference light into frequency components to receive the light, and an in-vivo dimension measuring means for measuring the in-vivo dimensions of the examined eye based on the receiving light signal obtained by the interference optical system. <P>COPYRIGHT: (C)2006,JPO&NCIPI

Description

本発明は被検眼の生体情報を非接触にて測定する眼科測定装置に関する。   The present invention relates to an ophthalmologic measurement apparatus that measures biological information of an eye to be examined without contact.

従来、眼の生体情報を取得して眼内レンズの設計や医療研究等が行われている。このような被検眼の生体情報を測定する装置としては、例えば被検眼の眼軸長と屈折力とを光学的に非接触にて測定する眼科測定装置が知られている。被検眼の眼軸長と屈折力とを非接触にて測定する装置では、眼底からの反射光と、装置内に設けられた参照面からの反射光との合成によって生じる干渉を用いて、基準位置からの被検眼眼底までの距離を求めておき、さらに別の光学系にて基準位置から被検眼の角膜までの距離を求めることによって、被検眼の眼軸長を算出するものとし、被検眼の屈折力は、屈折力補正を行うための光軸方向に移動可能な合焦レンズを光軸方向に移動させ、その移動量によって求める装置が知られている(特許文献1参照)。
特開平7−255674号公報
Conventionally, intraocular lens design, medical research, and the like have been performed by acquiring biological information of the eye. As an apparatus for measuring such biological information of the eye to be examined, for example, an ophthalmologic measurement apparatus that measures the axial length and refractive power of the eye to be examined in an optical non-contact manner is known. In a device that measures the axial length and refractive power of the eye to be examined in a non-contact manner, the interference is generated by combining the reflected light from the fundus and the reflected light from the reference surface provided in the device. The axial length of the eye to be examined is calculated by obtaining the distance from the position to the fundus of the eye to be examined, and further obtaining the distance from the reference position to the cornea of the eye to be examined by another optical system. An apparatus is known in which the refractive power is determined by moving the focusing lens movable in the optical axis direction for correcting the refractive power in the optical axis direction and moving the focusing lens (see Patent Document 1).
JP-A-7-255684

しかしながら、前述したような従来の眼科測定装置においては、屈折力と眼軸長の2種類の生体情報しか得ることができない。被検眼の生体情報としては、屈折力を始め、眼軸長や角膜厚、水晶体の厚さ、前房深度等の種々の情報があるが、これらの生体情報を一度に得ることのできる装置が望まれている。
本発明は、上記従来技術の問題点に鑑み、一台にて眼の種々の生体情報を測定・取得できる眼科測定装置を提供することを技術課題とする。
However, the conventional ophthalmic measuring apparatus as described above can obtain only two types of biological information, that is, refractive power and axial length. The biological information of the eye to be examined includes various information such as refractive power, axial length, corneal thickness, crystalline lens thickness, anterior chamber depth, and the like. There is an apparatus that can obtain such biological information at a time. It is desired.
An object of the present invention is to provide an ophthalmologic measuring apparatus capable of measuring and acquiring various biological information of an eye with a single unit in view of the above-described problems of the prior art.

上記課題を解決するために、本発明は以下のような構成を備えることを特徴とする。
(1) 被検眼の屈折力と眼軸長を非接触にて測定する眼科測定装置において、被検眼に向けて低コヒーレント長の光を照射する測定光照射光学系と、被検眼に向けて照射した前記低コヒーレント長の光による被検眼眼底からの反射光を受光する受光光学系と、受光光学系にて受光した前記反射光の受光状態に基づいて被検眼の屈折力を求める屈折力測定手段と、前記低コヒーレント長の光の照射によって得られる前記被検眼の前眼部からの反射光を参照光とする参照光照射光学系と、該参照光照射光学系によって得られる参照光と前記測定光照射光学系によって得られる前記被検眼眼底からの反射光とを合成して干渉させ,得られた干渉光を周波数成分に分光して受光する干渉光学系と、該干渉光学系にて得られる受光信号に基づいて被検眼の生体内寸法を測定する生体内寸法測定手段と、を備えることを特徴とする。
(2) (1)の眼科測定装置において、前記干渉光学系は参照光もしくは測定光の光路長を可変とする光路長可変手段と,合成した前記光束を前記周波数成分に分光させるための分光手段と該分光手段にて分光された各光束を受光素子に受光させるための光学部材とを有し、前記生体内寸法測定手段は前記受光素子から出力される受光信号をフーリエ変換を用いて解析した解析結果と前記光路長可変手段の変化量とに基づいて前記被検眼の眼軸長を測定するとともに,前記解析結果に基づいて被検眼の前眼部における生体内寸法を測定することを特徴とする。
(3) (2)の眼科測定装置は、前記屈折力測定手段によって得られた被検眼の屈折力に基づいて前記被検眼の屈折力を補正する屈折力補正手段を備えることを特徴とする。
(4) (1)〜(3)の眼科測定装置は、前記参照光照射光学系によって前記被検眼に向けて照射する光束を被検眼に対して走査するための走査手段と、該走査手段によって走査された光束による前記参照光と前記被検眼眼底からの反射光との合成光束を受光する前記干渉光学系にて得られる受光信号をフーリエ変換を用いて解析し、該解析結果に基づいて前記被検眼の断面画像を求める画像情報処理手段と、該画像情報処理手段にて得られた前記断面画像を表示する表示手段と、を有することを特徴とする。
(5) 被検眼眼底に向けて測定光を照射する測定光照射光学系と、被検眼眼底からの反射光を受光し,該受光した反射光の受光状態に基づいて被検眼の屈折力を求める屈折力測定手段と、該屈折力測定手段によって得られた被検眼の屈折力に基づいて前記被検眼の屈折力を補正する屈折力補正手段と、低コヒーレント長の光を被検眼に照射し,前記屈折力補正手段によって被検眼眼底での集光状態が補正された前記低コヒーレント長の光の眼底からの反射光と前眼部にて反射された前記低コヒーレント長の光の反射光とを合成して干渉させ,得られた干渉光を受光素子の受光面に集光させる干渉光学系と、該受光素子の受光面に集光した前記干渉光による受光信号に基づいて被検眼の生体内寸法を測定する生体内寸法測定手段と、を備えることを特徴とする。
In order to solve the above problems, the present invention is characterized by having the following configuration.
(1) In an ophthalmologic measurement apparatus that measures the refractive power and the axial length of the eye to be examined in a non-contact manner, the measurement light irradiation optical system that irradiates the eye to be examined with light having a low coherent length, and the light that is emitted toward the eye to be examined A light-receiving optical system that receives reflected light from the fundus of the eye to be examined by the low-coherent length light, and a refractive power measurement unit that obtains the refractive power of the eye to be examined based on the light-receiving state of the reflected light received by the light-receiving optical system A reference light irradiation optical system using, as a reference light, reflected light from the anterior eye part of the eye to be examined obtained by irradiation with light of the low coherent length, the reference light obtained by the reference light irradiation optical system, and the measurement Interference optical system that synthesizes and interferes with the reflected light from the fundus of the eye to be inspected obtained by the light irradiation optical system, and obtains the interference light obtained by splitting the obtained interference light into frequency components, and obtained by the interference optical system Eye to be examined based on received light signal And in-vivo dimension measuring means for measuring the in-vivo dimension.
(2) In the ophthalmic measurement apparatus according to (1), the interference optical system includes an optical path length varying unit that varies an optical path length of the reference light or the measuring light, and a spectral unit that causes the combined light beam to be split into the frequency components. And an optical member for causing the light receiving element to receive each light beam split by the spectroscopic means, and the in-vivo dimension measuring means analyzed the received light signal output from the light receiving element using Fourier transform The axial length of the eye to be examined is measured based on the analysis result and the amount of change of the optical path length varying means, and the in-vivo dimensions of the anterior eye portion of the eye to be examined are measured based on the analysis result. To do.
(3) The ophthalmologic measurement apparatus according to (2) includes a refractive power correction unit that corrects the refractive power of the eye to be examined based on the refractive power of the eye to be examined obtained by the refractive power measurement unit.
(4) The ophthalmic measuring apparatus according to any one of (1) to (3) includes a scanning unit that scans the eye to be inspected with the reference light irradiation optical system toward the eye to be examined, and the scanning unit. A light reception signal obtained by the interference optical system that receives a combined light beam of the reference light beam and the reflected light beam from the fundus of the eye to be examined is analyzed using Fourier transform, and the analysis is performed based on the analysis result. Image processing means for obtaining a cross-sectional image of the eye to be examined, and display means for displaying the cross-sectional image obtained by the image information processing means.
(5) Measuring light irradiation optical system for irradiating measurement light toward the fundus of the subject to be examined and light reflected from the fundus of the eye to be examined are received, and the refractive power of the eye to be examined is obtained based on the light receiving state of the received reflected light Refracting power measuring means, refracting power correcting means for correcting the refracting power of the subject eye based on the refracting power of the subject eye obtained by the refracting power measuring means, and irradiating the subject eye with light of low coherent length, The reflected light from the fundus of the low-coherent length light corrected in the light condensing state on the fundus of the eye to be examined by the refractive power correcting means and the reflected light of the low-coherent length light reflected from the anterior eye part. An interference optical system for synthesizing and interfering and condensing the obtained interference light on the light receiving surface of the light receiving element, and in vivo of the eye to be inspected based on the light reception signal by the interference light collected on the light receiving surface of the light receiving element In vivo dimension measuring means for measuring dimensions. And features.

本発明によれば、従来複数の装置にて測定していた眼の種々の生体情報を一度に得ることができ、測定時間を短縮することができる。   According to the present invention, it is possible to obtain various biological information of the eye that has been conventionally measured by a plurality of devices, and to shorten the measurement time.

以下、本発明の実施形態を図面に基づいて説明する。図1は本実施形態で用いる眼科測定装置の1種である屈折力測定機能を有した眼軸長測定装置の光学系の概略構成を示す図である。図1に示す光学系は、測定光投光光学系、屈折力測定光学系、参照光投光光学系、干渉信号検出光学系、視標投影光学系、観察光学系からなる。なお、本実施形態の眼科測定装置は被検眼に対して装置を所定の関係に位置させるためのアライメント光学系も有しているが、従来、他覚的眼屈折力装置等に用いられている既知のアライメント光学系と同様の光学系を用いればよいため、その説明は割愛する。   Hereinafter, embodiments of the present invention will be described with reference to the drawings. FIG. 1 is a diagram showing a schematic configuration of an optical system of an axial length measuring apparatus having a refractive power measuring function, which is one type of ophthalmic measuring apparatus used in the present embodiment. The optical system shown in FIG. 1 includes a measurement light projection optical system, a refractive power measurement optical system, a reference light projection optical system, an interference signal detection optical system, a target projection optical system, and an observation optical system. Note that the ophthalmic measurement apparatus according to the present embodiment also has an alignment optical system for positioning the apparatus in a predetermined relationship with respect to the eye to be examined, but has been conventionally used for an objective eye refractive power apparatus or the like. Since an optical system similar to a known alignment optical system may be used, the description thereof is omitted.

<測定光投光光学系>
図1に示す測定光投光光学系100は、光源1、コリメーターレンズ2、ビームスプリッタ3、集光レンズ4、リレーレンズ5、絞り6、ホールミラー7、ビームスプリッタ8、対物レンズ9、ビームスプリッタ10にて構成されている。
<Measurement light projection optical system>
A measuring light projecting optical system 100 shown in FIG. 1 includes a light source 1, a collimator lens 2, a beam splitter 3, a condenser lens 4, a relay lens 5, a diaphragm 6, a hall mirror 7, a beam splitter 8, an objective lens 9, and a beam. A splitter 10 is used.

光源1は、SLD(Super luminescent Diode)等の低コヒーレント長の赤外光を発する光源である。光源1から出射された低コヒーレント光は、コリメーターレンズ2にて平行光束とされた後、ビームスプリッタ3を透過する。ビームスプリッタ3を透過した光束は、集光レンズ4により光軸L1上に中間像(集光点A)を形成した後、リレーレンズ5、ホールミラーの開口部を通過して、一旦集光し、ビームスプリッタ8、対物レンズ9、ビームスプリッタ10を経て、被検眼Eの眼底に集光する。   The light source 1 is a light source that emits low-coherent infrared light such as SLD (Super luminescent Diode). The low coherent light emitted from the light source 1 is converted into a parallel light beam by the collimator lens 2 and then transmitted through the beam splitter 3. The light beam that has passed through the beam splitter 3 forms an intermediate image (condensing point A) on the optical axis L1 by the condensing lens 4, and then passes through the relay lens 5 and the opening of the hall mirror, and is condensed once. Then, the light is condensed on the fundus of the eye E through the beam splitter 8, the objective lens 9, and the beam splitter 10.

<屈折力測定光学系>
図1に示す屈折力測定光学系200は、被検眼Eの前方からビームスプリッタ10、対物レンズ9、ビームスプリッタ8、ホールミラー7、リレーレンズ11、ミラー12、絞り13、コリメータレンズ14、ビームスプリッタ15、リングレンズ16、赤外域に感度を有する受光素子17にて構成されている。なお、測定光投光光学系100とは、ホールミラー7からビームスプリッタ10までを共有する。
<Optical power measurement optical system>
A refractive power measuring optical system 200 shown in FIG. 1 includes a beam splitter 10, an objective lens 9, a beam splitter 8, a hall mirror 7, a relay lens 11, a mirror 12, a diaphragm 13, a collimator lens 14, and a beam splitter from the front of the eye E. 15, a ring lens 16, and a light receiving element 17 having sensitivity in the infrared region. The measurement light projecting optical system 100 shares the hall mirror 7 to the beam splitter 10.

測定光投光光学系100によって被検眼Eの眼底に集光された光束の反射光(測定光)は、ビームスプリッタ10、対物レンズ9、ビームスプリッタ8を経て、ホールミラー7にて反射する。なお、ホールミラー7は、被検眼Eにおける眼底反射光を反射し、不要な角膜反射光は開口部を通過させるようになっている。
ホールミラー7にて反射した眼底反射光は、リレーレンズ11を経た後、ミラー12にて折り曲げられた後、絞り13の位置にて一旦集光(集光点B)する。その後、反射光はコリメーターレンズ14によって平行光束とされた後、ビームスプリッタ15にて反射光の一部が反射し、リングレンズ16を経て、2次元受光素子17に受光される。
The reflected light (measurement light) of the light beam collected on the fundus of the eye E by the measurement light projection optical system 100 is reflected by the Hall mirror 7 through the beam splitter 10, the objective lens 9, and the beam splitter 8. The hall mirror 7 reflects fundus reflected light from the eye E, and unnecessary corneal reflected light passes through the opening.
The fundus reflection light reflected by the hall mirror 7 passes through the relay lens 11, is bent by the mirror 12, and is then condensed (condensing point B) at the position of the diaphragm 13. Thereafter, the reflected light is converted into a parallel light beam by the collimator lens 14, and then a part of the reflected light is reflected by the beam splitter 15, and is received by the two-dimensional light receiving element 17 through the ring lens 16.

なお、測定光投光光学系100の集光レンズ4による集光点Aと、コリメータレンズ14の前側焦点位置である絞り13位置の集光点Bは、対物レンズ9及びリレーレンズ5,11を介して被検眼Eの眼底と共役になっている。また、図1に示す集光レンズ4、絞り13、コリメーターレンズ14、ビームスプリッタ15、リングレンズ16、受光素子17は、駆動可能なステージ18上に設置されており、ステージ18は、図2に示す駆動手段53によって光軸方向に移動可能となっている。   Note that the condensing point A by the condensing lens 4 of the measurement light projecting optical system 100 and the condensing point B at the position of the stop 13 which is the front focal position of the collimator lens 14 are connected to the objective lens 9 and the relay lenses 5 and 11. Through the eye fundus of the eye E to be examined. Further, the condenser lens 4, the aperture 13, the collimator lens 14, the beam splitter 15, the ring lens 16, and the light receiving element 17 shown in FIG. 1 are installed on a drivable stage 18, and the stage 18 is shown in FIG. It can be moved in the optical axis direction by the driving means 53 shown in FIG.

また、リングレンズ16は、コリメーターレンズ14の後ろ側焦点位置に置かれ、駆動手段19によるステージ18の移動位置によらず被検眼Eの瞳と共役な関係が保たれている。さらに受光素子17は、リングレンズ16の焦点位置にあり、被検眼Eの眼底と共役な関係が成り立っている。なお、リングレンズ16は、平板上に円筒レンズをリング状に形成したものであり、リング部以外は遮光のためのコーティングが施されている。このリングレンズ16に平行光束が入射すると、焦点位置(受光素子17の受光面)には、リングレンズ16と略同じサイズのリング像が集光する。   Further, the ring lens 16 is placed at the back focal position of the collimator lens 14 and maintains a conjugate relationship with the pupil of the eye E regardless of the movement position of the stage 18 by the driving means 19. Furthermore, the light receiving element 17 is at the focal position of the ring lens 16 and has a conjugate relationship with the fundus of the eye E to be examined. The ring lens 16 is formed by forming a cylindrical lens in a ring shape on a flat plate, and a coating for light shielding is applied except for the ring portion. When a parallel light beam enters the ring lens 16, a ring image having substantially the same size as the ring lens 16 is condensed at the focal position (the light receiving surface of the light receiving element 17).

<参照光投光光学系>
図1に示す参照光学系300は、光源側から、光源1、コリメーターレンズ2、ビームスプリッタ3、ミラー19、ビームスプリッタ20、集光レンズ21、ミラー22、ビームスプリッタ8、対物レンズ9、ビームスプリッタ10にて構成されている。なお、測定光投光光学系100とは、光源1からビームスプリッタ3までと、ビームスプリッタ8からビームスプリッタ10までを共有する。
光源1から出射した低コヒーレント光は、コリメーターレンズ2を通過した後、ビームスプリッタ3にて一部の光束が反射し、光軸L2上に配置されているミラー19に向かう。ミラー19にて反射した光束は、ビームスプリッタ20を透過した後、集光レンズ21により、光軸L2上に一旦集光する。光軸L2上にて集光した光束は、ミラー22により反射した後、ビームスプリッタ8にて反射することにより光軸L1と同軸になり、対物レンズ9、ビームスプリッタ10を経て、被検眼Eの角膜に集光する。
<Reference light projection optical system>
A reference optical system 300 shown in FIG. 1 includes a light source 1, a collimator lens 2, a beam splitter 3, a mirror 19, a beam splitter 20, a condenser lens 21, a mirror 22, a beam splitter 8, an objective lens 9, and a beam from the light source side. A splitter 10 is used. The measurement light projecting optical system 100 shares the light source 1 to the beam splitter 3 and the beam splitter 8 to the beam splitter 10.
After the low-coherent light emitted from the light source 1 passes through the collimator lens 2, a part of the light beam is reflected by the beam splitter 3 and travels to the mirror 19 disposed on the optical axis L2. The light beam reflected by the mirror 19 passes through the beam splitter 20 and is then condensed by the condenser lens 21 on the optical axis L2. The light beam condensed on the optical axis L2 is reflected by the mirror 22 and then reflected by the beam splitter 8 so as to be coaxial with the optical axis L1, passes through the objective lens 9 and the beam splitter 10, and passes through the eye E. Focus on the cornea.

<干渉信号検出光学系>
図1に示す干渉信号検出光学系400は、被検眼Eの眼底からの反射光(測定光)を受光するための光学系と被検眼Eの角膜からの反射光(参照光)を受光するための光学系とから構成される。
<Interference signal detection optical system>
An interference signal detection optical system 400 shown in FIG. 1 receives an optical system for receiving reflected light (measurement light) from the fundus of the eye E and a reflected light (reference light) from the cornea of the eye E. Optical system.

眼底からの反射光を受光する光学系は、被検眼Eの前方からビームスプリッタ10、対物レンズ9、ビームスプリッタ8、ホールミラー7、リレーレンズ11、ミラー12、絞り13、コリメータレンズ14、ビームスプリッタ15、ビームスプリッタ26、ミラー27、集光レンズ28、エキスパンダレンズ29、グレーティングミラー(回折格子)30、集光レンズ31、円柱レンズ32、受光素子33にて構成されている。受光素子33は、赤外域に感度を有する一次元素子を用いている。なお、測定光投光光学系100とは、ビームスプリッタ10からビームスプリッタ15までを共有する。   The optical system that receives the reflected light from the fundus includes a beam splitter 10, an objective lens 9, a beam splitter 8, a hall mirror 7, a relay lens 11, a mirror 12, an aperture 13, a collimator lens 14, and a beam splitter from the front of the eye E to be examined. 15, a beam splitter 26, a mirror 27, a condenser lens 28, an expander lens 29, a grating mirror (diffraction grating) 30, a condenser lens 31, a cylindrical lens 32, and a light receiving element 33. The light receiving element 33 uses a one-dimensional element having sensitivity in the infrared region. The measurement light projecting optical system 100 shares the beam splitter 10 to the beam splitter 15.

測定光投光光学系100によって被検眼Eの眼底に集光された光束の反射光は、前述したように、屈折力測定光学系200各種光学部材を経た後、ビームスプリッタ15によって、一部の反射光が透過する。ビームスプリッタ15を透過した反射光は、さらに光軸L3上に配置されるビームスプリッタ26を経てミラー27にて反射し、集光レンズ28経て一旦集光する。集光レンズ28にて集光した反射光は、エキスパンダレンズ29にて光束径を広げられた後、グレーティングミラー30にて周波数成分に分光される。周波数成分に分光された反射光は、集光レンズ31、円柱レンズ32を経て、受光素子33の受光面に集光する。なお、エキスパンダレンズ29通過後の光束径、グレーティングミラーの格子間隔および入射角、集光レンズ28、受光素子33は、被検眼光軸方向の測定範囲と分解能を考慮して最適化されている。   As described above, the reflected light of the light beam collected on the fundus of the eye E by the measurement light projection optical system 100 passes through various optical members of the refractive power measurement optical system 200 and then is partially reflected by the beam splitter 15. Reflected light is transmitted. The reflected light that has passed through the beam splitter 15 is further reflected by the mirror 27 via the beam splitter 26 disposed on the optical axis L3, and once condensed through the condenser lens 28. The reflected light collected by the condensing lens 28 is expanded in diameter by the expander lens 29 and then split into frequency components by the grating mirror 30. The reflected light split into frequency components is condensed on the light receiving surface of the light receiving element 33 through the condenser lens 31 and the cylindrical lens 32. The beam diameter after passing through the expander lens 29, the grating interval and incident angle of the grating mirror, the condensing lens 28, and the light receiving element 33 are optimized in consideration of the measurement range and resolution in the optical axis direction of the eye to be examined. .

また、被検眼Eの角膜からの反射光(以下、参照光と記す)を受光するための光学系は、被検眼Eの前方からビームスプリッタ10、対物レンズ9、ビームスプリッタ8、ミラー22、集光レンズ21、ビームスプリッタ20、プリズム23、ミラー24,25、ビームスプリッタ26、ミラー27、集光レンズ28、エキスパンダレンズ29、グレーティングミラー30、集光レンズ31、円柱レンズ32、受光素子33にて構成されている。なお、プリズム23は、図2に示す駆動手段54により、図示する矢印方向に移動可能となっており、参照光が通る光路長を変更することができるようになっている。   An optical system for receiving reflected light from the cornea of the eye E (hereinafter referred to as reference light) includes a beam splitter 10, an objective lens 9, a beam splitter 8, a mirror 22, Optical lens 21, beam splitter 20, prism 23, mirrors 24 and 25, beam splitter 26, mirror 27, condenser lens 28, expander lens 29, grating mirror 30, condenser lens 31, cylindrical lens 32, and light receiving element 33 Configured. The prism 23 can be moved in the direction of the arrow shown by the driving means 54 shown in FIG. 2 so that the optical path length through which the reference light passes can be changed.

参照光は、ビームスプリッタ10、対物レンズ9を経た後、ビームスプリッタ8にてその一部が反射される。ビームスプリッタ8にて反射した参照光は、ミラー22、集光レンズ22を経た後、ビームスプリッタ20により反射され、プリズム23に向かう。プリズム23にて折り返された参照光は、ミラー24,25を経てビームスプリッタ26に向かう。ビームスプリッタ26にて反射した参照光は、眼底からの反射光と合成される。眼底からの反射光と合成された参照光は、眼底からの反射光と同じようにミラー27、集光レンズ28、エキスパンダレンズ29を経た後、グレーティングミラー30により周波数成分に分光され、円柱レンズ32を経て受光素子33に集光する。このようにグレーティングミラー30、集光レンズ31、円柱レンズ32、受光素子33にて、スペクトロメータ部を形成する。なお、受光素子33の受光面は、被検眼Eの眼底と角膜とに共役な関係となっている。なお、円柱レンズ32は受光素子33の幅方向に光束径を広げる役目を果たし、受光素子33の設置誤差によらず、光束を受光面に受光させるために用いる。   A part of the reference light is reflected by the beam splitter 8 after passing through the beam splitter 10 and the objective lens 9. The reference light reflected by the beam splitter 8 passes through the mirror 22 and the condenser lens 22, is reflected by the beam splitter 20, and travels toward the prism 23. The reference light returned by the prism 23 travels to the beam splitter 26 via the mirrors 24 and 25. The reference light reflected by the beam splitter 26 is combined with the reflected light from the fundus. The reference light combined with the reflected light from the fundus passes through the mirror 27, the condensing lens 28, and the expander lens 29 in the same manner as the reflected light from the fundus, and then is split into frequency components by the grating mirror 30 to be a cylindrical lens. Then, the light is condensed on the light receiving element 33. Thus, the spectrometer unit is formed by the grating mirror 30, the condensing lens 31, the cylindrical lens 32, and the light receiving element 33. The light receiving surface of the light receiving element 33 has a conjugate relationship with the fundus of the eye E and the cornea. The cylindrical lens 32 serves to widen the diameter of the light beam in the width direction of the light receiving element 33, and is used to receive the light beam on the light receiving surface regardless of the installation error of the light receiving element 33.

<視標投影光学系・観察光学系>
図1に示す視標投影光学系は、可視光を照射するLED等の光源34、所定の視標が形成された視標板35、リレーレンズ36、ビームスプリッタ37対物レンズ38、ビームスプリッタ10からなる。光源34から出射された可視光の光束は、視標板35を背面から照明する。視標板35を通過した光束は、リレーレンズ36、ビームスプリッタ37、対物レンズ38、ビームスプリッタ10を経て、被検眼Eの眼底に結像する。なお、本装置が被検眼Eに対して所定の位置関係になるようにアライメントされたとき、視標板31と被検眼Eの眼底とは共役な関係となる。また、光源34と視標板35は駆動手段55によって光軸方向に移動可能となっており、被検眼の固視や、視標板の位置を変更させて眼屈折力測定時に被検眼に雲霧をかけたり、調節負荷を与える。
<Target projection optical system / observation optical system>
1 includes a light source 34 such as an LED that emits visible light, a target plate 35 on which a predetermined target is formed, a relay lens 36, a beam splitter 37, an objective lens 38, and a beam splitter 10. Become. The visible light beam emitted from the light source 34 illuminates the target plate 35 from the back. The light beam that has passed through the target plate 35 forms an image on the fundus of the eye E through the relay lens 36, the beam splitter 37, the objective lens 38, and the beam splitter 10. When the apparatus is aligned so as to have a predetermined positional relationship with the eye E, the target plate 31 and the fundus of the eye E have a conjugate relationship. In addition, the light source 34 and the target plate 35 can be moved in the optical axis direction by the driving means 55, and the subject's eye can be fixed or the position of the target plate can be changed to measure the refractive power of the subject's eye. Or apply an adjustment load.

また、観察光学系は、被検眼前方から、ビームスプリッタ10、対物レンズ38、ビームスプリッタ37、結像レンズ39、赤外域に感度を有する受光素子40から構成される。なお、被検眼Eの瞳位置と受光素子40とは共役な位置関係となっている。なお、被検眼Eを照明するために、また、41は被検眼を照明するための赤外LEDである。   The observation optical system includes a beam splitter 10, an objective lens 38, a beam splitter 37, an imaging lens 39, and a light receiving element 40 having sensitivity in the infrared region from the front of the eye to be examined. Note that the pupil position of the eye E and the light receiving element 40 have a conjugate positional relationship. In addition, in order to illuminate the eye E, 41 is an infrared LED for illuminating the eye to be examined.

図2は本実施形態で用いる眼科測定装置における制御系を示したブロック図である。
50は本実施形態の装置の駆動制御を行う制御部である。制御部50には、受光素子17,受光素子33,受光素子40、モニタ51、演算処理部52、駆動手段53〜55、記憶部56等が接続される。なお、駆動手段53〜55はパルスモータ等を用いており、各駆動手段による駆動量を検出できるようになっている。また、演算処理部52は、受光素子や駆動手段等によって得られた情報を基に、被検眼Eの屈折力や眼軸長等の生体情報を演算により求めたり、被検眼の断面画像を形成するために用いられる。また、記憶部56には求められた測定値が記憶される。
FIG. 2 is a block diagram showing a control system in the ophthalmic measurement apparatus used in the present embodiment.
A control unit 50 performs drive control of the apparatus according to the present embodiment. The control unit 50 is connected to the light receiving element 17, the light receiving element 33, the light receiving element 40, a monitor 51, an arithmetic processing unit 52, driving means 53 to 55, a storage unit 56, and the like. The driving means 53 to 55 use pulse motors or the like, and can detect the driving amount by each driving means. In addition, the arithmetic processing unit 52 obtains biological information such as refractive power and axial length of the eye E by calculation based on information obtained by the light receiving element, driving means, etc., and forms a cross-sectional image of the eye to be examined. Used to do. Further, the obtained measurement value is stored in the storage unit 56.

以上のような、構成を備える装置について、以下にその動作を説明する。
検者は、図1に示すモニタ51を見ながら、図示なきジョイスティック等の操作手段を用いて、装置を上下左右及び前後方向に移動させ、装置を被検眼Eに対して所定の位置関係に置く。なお、本実施形態では、受光素子36の受光面と被検眼Eの瞳位置とが共役な関係になるようにしている。検者は図1に示す視標投影光学系にて投影される視標を被検者に固視させるとともに、図示なき測定ボタンを使用して、被検眼Eの生体情報を求める。
The operation of the apparatus having the above configuration will be described below.
While looking at the monitor 51 shown in FIG. 1, the examiner moves the apparatus in the vertical and horizontal directions and the front and rear direction using an operation unit such as a joystick (not shown) to place the apparatus in a predetermined positional relationship with the eye E to be examined. . In the present embodiment, the light receiving surface of the light receiving element 36 and the pupil position of the eye E to be examined are in a conjugate relationship. The examiner causes the subject to fixate the target projected by the target projection optical system shown in FIG. 1, and obtains biological information of the eye E using a measurement button (not shown).

測定ボタンが押されると、制御部50は、駆動手段55を駆動させて、光源34及び視標板35を光軸方向に移動させ、雲霧がかかる状態とし、被検眼Eの調節をなくすようにする。また、制御部50は、光源1から低コヒーレント光を出射させる。光源1から出射した低コヒーレント光は、図1に示すビームスプリッタ3により2方向に分けられた後、前述した測定光投光光学系100及び参照光投光光学系300を経て、被検眼Eの眼底及び角膜に各々集光する。   When the measurement button is pressed, the control unit 50 drives the driving unit 55 to move the light source 34 and the target plate 35 in the optical axis direction so as to be in a cloudy state so that the eye E is not adjusted. To do. Further, the control unit 50 emits low coherent light from the light source 1. The low-coherent light emitted from the light source 1 is divided into two directions by the beam splitter 3 shown in FIG. 1, and then passes through the measurement light projection optical system 100 and the reference light projection optical system 300 described above. Focuses on the fundus and cornea, respectively.

被検眼Eの眼底に集光した光束の反射光は、図1に示すビームスプリッタ10、対物レンズ9、ビームスプリッタ8を経た後、ホールミラー7により反射される。ホールミラー7にて反射した眼底反射光は、リレーレンズ11、ミラー12、絞り13、コリメーターレンズ14を経た後、ビームスプリッタ15にてその一部が下方に折り曲げられ、リングレンズ16を経て受光素子17に受光される。   The reflected light of the light beam collected on the fundus of the eye E is reflected by the Hall mirror 7 after passing through the beam splitter 10, the objective lens 9 and the beam splitter 8 shown in FIG. 1. The fundus reflection light reflected by the hall mirror 7 passes through the relay lens 11, the mirror 12, the diaphragm 13, and the collimator lens 14, and then a part thereof is bent downward by the beam splitter 15 and received through the ring lens 16. Light is received by the element 17.

図3は眼底からの反射光が、リングレンズ16を経て受光素子17に受光される状態を示した概略図である。例えば、被検眼Eが正視眼の場合、コリメータレンズ14を通った反射光は、図3(a)に示すような平行光束となってリングレンズ16を透過する。このときリングレンズ16を経て受光素子17に受光されるリング像R1は、リングレンズ16と略同じサイズとなる。また、被検眼Eが近視眼の場合には、コリメータレンズ14を通った反射光は、図3(b)に示すような収束光となってリングレンズ16を透過する。このとき、リングレンズ16を経て受光素子17に受光されるリング像R2は、図3(a)に示したリング像R1よりも太くなるとともに、小さな径となる。また、被検眼Eが遠視眼の場合には、コリメータレンズ14を通った反射光は、図3(c)に示すような収束光となってリングレンズ16を透過する。このとき、リングレンズ16を経て受光素子17に受光されるリング像R3は、図3(a)に示したリング像R1よりも太くなるとともに、大きな径となる。 FIG. 3 is a schematic view showing a state in which reflected light from the fundus is received by the light receiving element 17 through the ring lens 16. For example, when the eye E is a normal eye, the reflected light that has passed through the collimator lens 14 passes through the ring lens 16 as a parallel light flux as shown in FIG. At this time, the ring image R 1 received by the light receiving element 17 through the ring lens 16 has substantially the same size as the ring lens 16. When the eye E is a myopic eye, the reflected light that has passed through the collimator lens 14 becomes convergent light as shown in FIG. 3B and passes through the ring lens 16. At this time, the ring image R 2 received by the light receiving element 17 through the ring lens 16 becomes thicker than the ring image R 1 shown in FIG. When the eye E is a hyperopic eye, the reflected light that has passed through the collimator lens 14 becomes convergent light as shown in FIG. 3C and passes through the ring lens 16. At this time, the ring image R 3 received by the light receiving element 17 through the ring lens 16 becomes thicker and has a larger diameter than the ring image R 1 shown in FIG.

演算処理部52は、被検眼が正視眼であるときの受光状態と、実際に受光素子17によって検出された受光状態との変化量に基づいて演算処理を行い、被検眼Eの屈折力を求める。また、演算処理部52は、算出した屈折力値または受光素子17の受光状態から、眼底に向けて投光する測定光が、被検眼Eの眼底において最も集光(ベストフォーカス)するためのステージ18の位置を算出する。演算処理部52は算出したベストフォーカスとなるステージ18の位置情報を制御部50に送る。制御部50は受け取った位置情報を基に駆動手段53を駆動してステージ18を移動させ、被検眼Eに対する屈折力補正を行う。このように被検眼Eに対する屈折力補正を行うことにより、屈折力に応じた前記測定光の眼底における集光状態を補正することができ、S/N比の良い干渉信号が得られることとなる。   The arithmetic processing unit 52 performs arithmetic processing based on the amount of change between the light receiving state when the eye to be examined is a normal eye and the light receiving state actually detected by the light receiving element 17 to obtain the refractive power of the eye E to be examined. . Further, the arithmetic processing unit 52 is a stage for the measurement light projected toward the fundus from the calculated refractive power value or the light receiving state of the light receiving element 17 to be most condensed (best focus) on the fundus of the eye E to be examined. 18 positions are calculated. The arithmetic processing unit 52 sends the calculated position information of the stage 18 that is the best focus to the control unit 50. The control unit 50 drives the driving means 53 based on the received position information to move the stage 18 and corrects the refractive power for the eye E. By correcting the refractive power for the eye E in this way, it is possible to correct the condensing state of the measurement light on the fundus according to the refractive power, and to obtain an interference signal with a good S / N ratio. .

なお、本実施の形態では受光素子17に受光されたリング像の受光状態に基づいて被検眼Eの屈折力を求めるものとしているが、これに限るものではなく、眼底に測定光を集光させるための、ベストフォーカス位置とされるステージ18の位置と、そのときのリング像の受光状態とを考慮して、被検眼Eの屈折力を求めるようにすることもできる。また、受光素子17に受光されるリング像の受光状態の情報は、ベストフォーカスを得るためのステージ18の位置情報を算出するのに用いておき、被検眼の屈折力はステージ18の基準位置からの移動量に基づいて求めることもできる。得られた被検眼Eの屈折力値は、記憶部56に記憶されるとともに、モニタ51に表示される。   In the present embodiment, the refractive power of the eye E is determined based on the light receiving state of the ring image received by the light receiving element 17, but the present invention is not limited to this, and the measurement light is condensed on the fundus. Therefore, the refractive power of the eye E can be obtained in consideration of the position of the stage 18 that is the best focus position and the light receiving state of the ring image at that time. The light reception state information of the ring image received by the light receiving element 17 is used to calculate the position information of the stage 18 for obtaining the best focus, and the refractive power of the eye to be examined is determined from the reference position of the stage 18. It can also be obtained based on the amount of movement. The obtained refractive power value of the eye E is stored in the storage unit 56 and displayed on the monitor 51.

ステージ18の移動によって被検眼Eの屈折力補正が行われることにより、測定光は被検眼Eの眼底に効率よく集光することとなる。眼底からの反射光は、図1に示した干渉信号検出光学系400における測定光を受光するための光学系によって最終的に受光素子33に集光される。また、参照光(被検眼Eの角膜反射光)は、干渉信号検出光学系400における前述した参照光を受光するための光学系によって最終的に受光素子33に集光される。なお、前述したように、眼底からの反射光と参照光とが合成された光束は、グレーティングミラー30により、周波数成分に分光され、集光レンズ31、円柱レンズ32を経て受光素子33に集光することとなる。受光素子33は、周波数成分に分光された反射光を受光し、周波数成分毎の干渉強度を出力する。演算処理部52は、受光素子33にて受光される測定光と参照光とによって得られる干渉強度をモニタする。   As the refractive power of the eye E is corrected by the movement of the stage 18, the measurement light is efficiently condensed on the fundus of the eye E. The reflected light from the fundus is finally condensed on the light receiving element 33 by the optical system for receiving the measurement light in the interference signal detecting optical system 400 shown in FIG. Further, the reference light (corneal reflection light of the eye E) is finally condensed on the light receiving element 33 by the optical system for receiving the reference light in the interference signal detection optical system 400. Note that, as described above, the light beam obtained by combining the reflected light from the fundus and the reference light is split into frequency components by the grating mirror 30, and is condensed on the light receiving element 33 through the condenser lens 31 and the cylindrical lens 32. Will be. The light receiving element 33 receives the reflected light separated into frequency components and outputs the interference intensity for each frequency component. The arithmetic processing unit 52 monitors the interference intensity obtained by the measurement light received by the light receiving element 33 and the reference light.

一方、制御部50は、駆動手段54を用いて図1に示すプリズム23を実線で示す基準位置(ここでは参照光路が最も短くなる位置)から移動させ、参照光が通る光学系の光路長を変化させていく。なお、本実施形態では眼軸長測定の間、プリズム23を一秒間に数回〜十数回程度往復運動をさせるものとしているが、これに限るものではなく、往復運動をさせず単にプリズム23を一方向に動かすのみでも良い。本実施形態で用いる測定光及び参照光は、低コヒーレント光を用いているため、測定光の光路長と参照光の光路長が等しくなったときに、測定光と参照光との合成にて得られる干渉光の信号強度が最も強くなることとなる。なお、受光素子33に受光される参照光には、角膜表面の反射光以外にも、角膜裏面や水晶体前後面等の位相物体からの反射光も含まれる。したがって、受光素子33が受光する干渉信号は、これらと眼底反射光との干渉が周波数の関数として受光されることとなる。   On the other hand, the control unit 50 uses the driving unit 54 to move the prism 23 shown in FIG. 1 from the reference position indicated by the solid line (here, the position where the reference optical path is the shortest), thereby setting the optical path length of the optical system through which the reference light passes. Change it. In this embodiment, during the measurement of the axial length, the prism 23 is reciprocated several times to several tens of times per second. However, the present invention is not limited to this. It may be only moved in one direction. Since the measurement light and the reference light used in this embodiment are low-coherent light, when the optical path length of the measurement light is equal to the optical path length of the reference light, it is obtained by combining the measurement light and the reference light. The signal intensity of the interference light to be generated is the strongest. The reference light received by the light receiving element 33 includes reflected light from phase objects such as the back surface of the cornea and the front and back surfaces of the crystalline lens, in addition to the reflected light from the surface of the cornea. Accordingly, the interference signal received by the light receiving element 33 is received as a function of frequency due to interference between these and the fundus reflection light.

演算処理部52は、干渉信号の強度が最も強くなったときの受光素子33から出力される検出信号をフーリエ変換を用いて解析する。干渉光には被検眼Eにおける各位相物体(例えば、角膜前後面、水晶体前後面、網膜等)からの反射光を含んでいるため、検出信号をフーリエ変換することによって、被検眼Eにおける角膜、水晶体等の各位相物体の深さ情報を得ることができる。演算処理部52は演算によって求められたプリズムの位置を基準とした角膜前面の位置情報と、プリズムの移動量(または駆動手段54の駆動量)とから被検眼Eの眼軸長を求める。また、得られた各位相物体の深さ情報から、その他の生体内寸法(例えば、角膜厚、前房深度、水晶体厚等の生体内寸法)を直接求める。求められた生体内寸法の情報は、記憶部56に記憶されるとともに、モニタ51に表示される。なお、本実施形態では参照光路に置かれたプリズムを移動させることにより、測定光の光路長と参照光の光路長とが等しくなるように参照光の光路長を変化させるものとしているが、これに限るものではなく、測定光の光路長を変化させるようにすることもできる。   The arithmetic processing unit 52 analyzes the detection signal output from the light receiving element 33 when the intensity of the interference signal becomes the highest using Fourier transform. Since the interference light includes reflected light from each phase object (for example, the front and back surfaces of the cornea, the front and rear surfaces of the lens, the retina, etc.) in the eye E, the cornea in the eye E is subjected to Fourier transform, Depth information of each phase object such as a crystalline lens can be obtained. The arithmetic processing unit 52 obtains the axial length of the eye E from the position information of the front surface of the cornea based on the position of the prism obtained by the computation and the movement amount of the prism (or the driving amount of the driving means 54). Further, other in-vivo dimensions (for example, in-vivo dimensions such as corneal thickness, anterior chamber depth, and lens thickness) are directly obtained from the obtained depth information of each phase object. Information on the obtained in-vivo dimensions is stored in the storage unit 56 and displayed on the monitor 51. In this embodiment, the optical path length of the reference light is changed by moving the prism placed in the reference optical path so that the optical path length of the measurement light and the optical path length of the reference light are equal. The optical path length of the measurement light can be changed.

また、さらに正確に眼軸長を求めたい場合には、図1に示す光学系において、コリメータレンズ14と集光レンズ27の間であって被検眼Eの瞳と共役な位置、あるいは対物レンズとホールミラーの間における被検眼Eの瞳とほぼ共役な位置に複数のシリンダレンズの組み合わせからなる乱視補正用光学部材を配置すればよい。この乱視補正用光学部材は、例えば、2枚のシリンダレンズの組み合わせからなるストークスのクロス円柱等を用いることができる。被検眼Eが乱視を有している場合、リングレンズ16を経て受光素子17に受光されるリング像は楕円形状となるため、演算処理部42を用いて、このリング像の受光状態を解析することにより、乱視度数及び乱視軸角度を求めることができる。求めた被検眼Eの乱視度数及び乱視軸角度を基に、被検眼Eの乱視成分を打ち消すように前述した乱視補正用光学部材を配置する。このような構成により、被検眼が乱視成分を持っていても眼底からの反射光は、効率よく受光素子33に集光し、測定の精度を高めることが可能となる。   In order to obtain the axial length more accurately, in the optical system shown in FIG. 1, a position conjugate between the collimator lens 14 and the condensing lens 27 and the pupil of the eye E to be examined, or an objective lens What is necessary is just to arrange | position the optical member for astigmatism correction which consists of a combination of a some cylinder lens in the position substantially conjugate with the pupil of the eye E to be examined between Hall mirrors. As the astigmatism correcting optical member, for example, a Stokes cross cylinder formed by a combination of two cylinder lenses can be used. When the eye E has astigmatism, the ring image received by the light receiving element 17 through the ring lens 16 has an elliptical shape. Therefore, the light receiving state of the ring image is analyzed using the arithmetic processing unit 42. Thus, the astigmatism power and the astigmatism axis angle can be obtained. The above-described astigmatism correcting optical member is arranged so as to cancel the astigmatism component of the eye E based on the obtained astigmatism power and astigmatism axis angle of the eye E. With such a configuration, even if the eye to be examined has an astigmatism component, the reflected light from the fundus can be efficiently condensed on the light receiving element 33 and the measurement accuracy can be improved.

なお、本実施の形態では、参照光を角膜表面に集光させるものとしているが、これに限るものではなく、被検眼内の位相物体(角膜、水晶体等)からの反射光が各周波数成分に分光された状態で受光素子に受光されればよく、例えば、参照光の集光位置を被検眼Eの瞳位置とすることもできる。
また、本実施形態では測定光と参照光との合成光を各周波数成分に分光するための分光手段としてグレーティングミラー(回折格子)を用いるものとしているが、これに限るものではなく、プリズムや音響光学素子等の他の分光手段を用いることもできる。
さらに、本実施形態では被検眼の屈折力を求めるために受光素子上にリング像を形成するものとしているが、これに限るものではない。例えば眼底からの反射光を光学部材を介して数個の点に分けて受光素子に集光させ、その受光像の受光状態に基づいて屈折力を求める等、干渉を用いず受光面に形成される受光像の位置変化や形状変化等の受光像の変化状態を検出することによって屈折力を求める構成であればよい。
In this embodiment, the reference light is focused on the corneal surface. However, the present invention is not limited to this, and reflected light from a phase object (cornea, crystalline lens, etc.) in the eye to be examined is included in each frequency component. It is only necessary that the light receiving element receives the light in a spectral state. For example, the condensing position of the reference light can be set as the pupil position of the eye E to be examined.
In this embodiment, a grating mirror (diffraction grating) is used as a spectroscopic means for splitting the combined light of the measurement light and the reference light into each frequency component. However, the present invention is not limited to this. Other spectroscopic means such as an optical element can also be used.
Furthermore, in this embodiment, a ring image is formed on the light receiving element in order to obtain the refractive power of the eye to be examined, but the present invention is not limited to this. For example, the reflected light from the fundus is divided into several points via an optical member and collected on the light receiving element, and the refractive power is calculated based on the light receiving state of the received light image. Any configuration may be used as long as the refractive power is obtained by detecting a change state of the received light image such as a change in position or shape of the received light image.

以上説明したように、本実施形態の眼科測定装置では、屈折力や眼軸長等の生体内寸法を一度に得ることができるものとしているが、さらに被検眼に向けて照射する光束を走査する走査手段を設け、得られる検出信号をスペクトル干渉の原理に基づいて解析することにより、被検眼の前眼部像を得ることができる。   As described above, in the ophthalmologic measurement apparatus according to the present embodiment, it is assumed that in vivo dimensions such as refractive power and axial length can be obtained at one time, but further scans the light beam irradiated toward the eye to be examined. By providing scanning means and analyzing the detection signal obtained based on the principle of spectral interference, an anterior segment image of the eye to be examined can be obtained.

図4は第2の実施形態として、図1の光学系に対して、被検眼に向けて照射する光束を走査する走査手段を設けた例を示した図である。なお、図1と同機能を有するものには同符号を付し、その説明は省略する。
図4において、60は被検眼に向けて照射する光束を走査するための走査手段となるガルバノミラーであり、所定の方向(本実施形態では被検眼に対して光束を上下方向に走査する方向)に回転駆動可能となっている。また、ガルバノミラー60の反射面は、対物レンズ9の焦点位置に配置されており、ミラーの回転角が光束の前眼部への入射高さに比例するとともに、駆動によって光路長が変化しないようになっている。なお、第2の実施形態における眼科測定装置を駆動制御するための制御系の構成は、ガルバノミラー60の駆動制御以外は、図2に示した制御系のブロック図と同様であるため、その説明は割愛する。
FIG. 4 is a diagram showing an example in which scanning means for scanning a light beam irradiated toward the eye to be examined is provided in the optical system of FIG. 1 as the second embodiment. Components having the same functions as those in FIG. 1 are denoted by the same reference numerals, and description thereof is omitted.
In FIG. 4, reference numeral 60 denotes a galvano mirror serving as a scanning unit for scanning a light beam emitted toward the eye to be examined, and in a predetermined direction (in this embodiment, a direction in which the light beam is scanned in the vertical direction with respect to the eye to be examined). Can be rotated. The reflection surface of the galvanometer mirror 60 is disposed at the focal position of the objective lens 9 so that the rotation angle of the mirror is proportional to the incident height of the light beam to the anterior eye part and the optical path length does not change by driving. It has become. The configuration of the control system for driving and controlling the ophthalmologic measurement apparatus according to the second embodiment is the same as the block diagram of the control system shown in FIG. Will be omitted.

図4に示す光源1から出射された低コヒーレント光のうち、ビームスプリッタ3を透過した光束は、測定光投光光学系100を経て被検眼Eの眼底に集光する。また、光源1から出射された低コヒーレント光のうち、ビームスプリッタ3にて反射した光束は、参照光投光光学系300を経て被検眼Eの角膜に集光する。被検眼Eの眼底からの反射光と角膜反射を含めた眼内の位相物体からの反射光との合成光は、干渉信号検出光学系400のグレーティングミラー300によって周波数成分に分光された状態で、受光素子33に集光する。受光素子33から出力される検出信号を、演算処理部にてフーリエ変換することによって、被検眼Eにおける角膜、水晶体等の各位相物体の深さ情報を得ることができる。なお、参照光投光光学系300を通る光束は、ガルバノミラー60によって被検眼Eに対して所定方向に走査されている。このため、受光素子33から出力される検出信号は、光束の走査によって得られる眼内の位相物体からの各反射光の情報を含むこととなる。演算処理部は、検出信号をフーリエ変換することによって得られた眼内における位相物体の深さ方向の情報を蓄積加算することによって、走査によって光切断された被検眼の前眼部断面像を求めることができる。得られた前眼部断面像は、図5に示すようにモニタ51に表示される。   Of the low-coherent light emitted from the light source 1 shown in FIG. 4, the light beam that has passed through the beam splitter 3 is condensed on the fundus of the eye E through the measurement light projecting optical system 100. Of the low-coherent light emitted from the light source 1, the light beam reflected by the beam splitter 3 is condensed on the cornea of the eye E through the reference light projecting optical system 300. The combined light of the reflected light from the fundus of the eye E and the reflected light from the intraocular phase object including corneal reflection is spectrally divided into frequency components by the grating mirror 300 of the interference signal detection optical system 400. The light is condensed on the light receiving element 33. Depth information of each phase object such as cornea and crystalline lens in the eye E can be obtained by performing Fourier transform on the detection signal output from the light receiving element 33 in the arithmetic processing unit. The light beam passing through the reference light projecting optical system 300 is scanned in a predetermined direction with respect to the eye E by the galvanometer mirror 60. For this reason, the detection signal output from the light receiving element 33 includes information on each reflected light from the intraocular phase object obtained by scanning the light beam. The arithmetic processing unit obtains a cross-sectional image of the anterior ocular segment of the eye to be inspected by scanning by accumulating and adding information in the depth direction of the phase object in the eye obtained by Fourier transforming the detection signal. be able to. The obtained anterior segment cross-sectional image is displayed on the monitor 51 as shown in FIG.

このように参照光束と物体光束とを用いて干渉させ、スペクトル干渉の原理にて解析を行うことにより、装置に対して被検眼の位置が多少ずれても、参照光束と物体光束の両方ともが同程度変化するため、アライメントずれやフォーカスずれに強く、被検眼の生体内寸法や断面像を得ることが可能となる。   In this way, by interfering with the reference light beam and the object light beam and performing analysis based on the principle of spectral interference, even if the position of the eye to be examined is slightly deviated from the apparatus, both the reference light beam and the object light beam are Since it changes to the same extent, it is resistant to misalignment and out of focus, and it is possible to obtain in-vivo dimensions and cross-sectional images of the eye to be examined.

本実施形態における眼科測定装置の光学系を示した図である。It is the figure which showed the optical system of the ophthalmic measurement apparatus in this embodiment. 本実施形態における眼科測定装置の制御系を示したブロック図である。It is the block diagram which showed the control system of the ophthalmologic measurement apparatus in this embodiment. リングレンズを透過した測定光の集光状態を示した図である。It is the figure which showed the condensing state of the measurement light which permeate | transmitted the ring lens. 第2の実施形態における眼科測定装置の光学系を示した図である。It is the figure which showed the optical system of the ophthalmic measurement apparatus in 2nd Embodiment. モニタに表示された被検眼前眼部像を示した図である。It is the figure which showed the to-be-examined eye part image displayed on the monitor.

符号の説明Explanation of symbols

1 光源
4 集光レンズ
7 ホールミラー
9 対物レンズ
14 コリメータレンズ
16 リングレンズ
17 受光素子
18 ステージ
23 プリズム
30 グレーティングミラー
31 集光レンズ
33 受光素子
50 制御部
51 モニタ
52 演算処理部





DESCRIPTION OF SYMBOLS 1 Light source 4 Condensing lens 7 Hall mirror 9 Objective lens 14 Collimator lens 16 Ring lens 17 Light receiving element 18 Stage 23 Prism 30 Grating mirror 31 Condensing lens 33 Light receiving element 50 Control part 51 Monitor 52 Calculation processing part





Claims (5)

被検眼の屈折力と眼軸長を非接触にて測定する眼科測定装置において、被検眼に向けて低コヒーレント長の光を照射する測定光照射光学系と、被検眼に向けて照射した前記低コヒーレント長の光による被検眼眼底からの反射光を受光する受光光学系と、受光光学系にて受光した前記反射光の受光状態に基づいて被検眼の屈折力を求める屈折力測定手段と、前記低コヒーレント長の光の照射によって得られる前記被検眼の前眼部からの反射光を参照光とする参照光照射光学系と、該参照光照射光学系によって得られる参照光と前記測定光照射光学系によって得られる前記被検眼眼底からの反射光とを合成して干渉させ,得られた干渉光を周波数成分に分光して受光する干渉光学系と、該干渉光学系にて得られる受光信号に基づいて被検眼の生体内寸法を測定する生体内寸法測定手段と、を備えることを特徴とする眼科測定装置。 In an ophthalmologic measurement apparatus that measures the refractive power and axial length of the eye to be examined in a non-contact manner, the measurement light irradiation optical system that irradiates the eye to be examined with light of a low coherent length, and the low light that is emitted toward the eye to be examined A light receiving optical system that receives reflected light from the fundus of the eye to be examined by coherent length light, a refractive power measuring unit that obtains the refractive power of the eye based on the light receiving state of the reflected light received by the light receiving optical system, and Reference light irradiation optical system using reference light as reflected light from the anterior segment of the eye to be examined obtained by irradiation with light of low coherent length, reference light obtained by the reference light irradiation optical system, and measurement light irradiation optics An interference optical system that synthesizes and interferes with the reflected light from the fundus of the eye to be inspected obtained by the system, spectrally separates the obtained interference light into frequency components, and receives light signals obtained by the interference optical system. Based on the subject's eye Ophthalmic measuring apparatus comprising: the in vivo size measuring means for measuring the dimensions, the. 請求項1の眼科測定装置において、前記干渉光学系は参照光もしくは測定光の光路長を可変とする光路長可変手段と,合成した前記光束を前記周波数成分に分光させるための分光手段と該分光手段にて分光された各光束を受光素子に受光させるための光学部材とを有し、前記生体内寸法測定手段は前記受光素子から出力される受光信号をフーリエ変換を用いて解析した解析結果と前記光路長可変手段の変化量とに基づいて前記被検眼の眼軸長を測定するとともに,前記解析結果に基づいて被検眼の前眼部における生体内寸法を測定することを特徴とする眼科測定装置。 2. The ophthalmologic measurement apparatus according to claim 1, wherein the interference optical system includes an optical path length varying unit that varies an optical path length of reference light or measurement light, a spectral unit that splits the synthesized light flux into the frequency component, and the spectral component. And an optical member for causing the light receiving element to receive each light beam dispersed by the means, and the in-vivo dimension measuring means analyzes the received light signal output from the light receiving element using Fourier transform; An ophthalmic measurement characterized in that the axial length of the eye to be examined is measured based on the amount of change of the optical path length varying means, and the in-vivo dimensions in the anterior segment of the eye to be examined are measured based on the analysis result. apparatus. 請求項2の眼科測定装置は、前記屈折力測定手段によって得られた被検眼の屈折力に基づいて前記被検眼の屈折力を補正する屈折力補正手段を備えることを特徴とする眼科測定装置。 The ophthalmic measurement apparatus according to claim 2, further comprising a refractive power correction unit that corrects the refractive power of the eye to be examined based on the refractive power of the eye to be examined obtained by the refractive power measurement unit. 請求項1〜3の眼科測定装置は、前記参照光照射光学系によって前記被検眼に向けて照射する光束を被検眼に対して走査するための走査手段と、該走査手段によって走査された光束による前記参照光と前記被検眼眼底からの反射光との合成光束を受光する前記干渉光学系にて得られる受光信号をフーリエ変換を用いて解析し、該解析結果に基づいて前記被検眼の断面画像を求める画像情報処理手段と、該画像情報処理手段にて得られた前記断面画像を表示する表示手段と、を有することを特徴とする眼科測定装置。 The ophthalmologic measurement apparatus according to any one of claims 1 to 3 includes a scanning unit that scans the eye to be inspected with the reference light irradiation optical system toward the eye to be inspected, and a light beam that has been scanned by the scanning unit. A received light signal obtained by the interference optical system that receives a combined light beam of the reference light and reflected light from the fundus of the eye to be examined is analyzed using Fourier transform, and a cross-sectional image of the eye to be examined is based on the analysis result An ophthalmologic measurement apparatus comprising: an image information processing means for obtaining the image information; and a display means for displaying the cross-sectional image obtained by the image information processing means. 被検眼眼底に向けて測定光を照射する測定光照射光学系と、被検眼眼底からの反射光を受光し,該受光した反射光の受光状態に基づいて被検眼の屈折力を求める屈折力測定手段と、該屈折力測定手段によって得られた被検眼の屈折力に基づいて前記被検眼の屈折力を補正する屈折力補正手段と、低コヒーレント長の光を被検眼に照射し,前記屈折力補正手段によって被検眼眼底での集光状態が補正された前記低コヒーレント長の光の眼底からの反射光と前眼部にて反射された前記低コヒーレント長の光の反射光とを合成して干渉させ,得られた干渉光を受光素子の受光面に集光させる干渉光学系と、該受光素子の受光面に集光した前記干渉光による受光信号に基づいて被検眼の生体内寸法を測定する生体内寸法測定手段と、を備えることを特徴とする眼科測定装置。



Measuring light irradiation optical system that irradiates measurement light toward the fundus of the eye to be examined, and refractive power measurement that receives the reflected light from the fundus of the eye to be examined and obtains the refractive power of the eye to be examined based on the light receiving state of the received reflected light Means, a refractive power correcting means for correcting the refractive power of the eye to be examined based on the refractive power of the eye to be examined obtained by the refractive power measuring means, and irradiating the eye to be examined with light having a low coherent length. By combining the reflected light from the fundus of the low coherent length light corrected by the correcting means on the fundus of the eye to be examined and the reflected light of the low coherent length reflected from the anterior eye part. Interferometric optical system for causing interference and condensing the obtained interference light on the light receiving surface of the light receiving element, and measuring the in-vivo dimensions of the eye to be examined based on the received light signal from the interference light collected on the light receiving surface of the light receiving element And in-vivo dimension measuring means. Ophthalmic measurement apparatus according to.



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JP2007215733A (en) * 2006-02-16 2007-08-30 Topcon Corp Eye fundus observation apparatus
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JP2019134908A (en) * 2018-02-05 2019-08-15 株式会社ニデック OCT apparatus and OCT control program
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US11311191B2 (en) 2018-09-28 2022-04-26 Tomey Corporation Ophthalmic apparatus

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