IL276010A - Methods of purifying cannabinoids using liquid:liquid chromatography - Google Patents
Methods of purifying cannabinoids using liquid:liquid chromatographyInfo
- Publication number
- IL276010A IL276010A IL276010A IL27601020A IL276010A IL 276010 A IL276010 A IL 276010A IL 276010 A IL276010 A IL 276010A IL 27601020 A IL27601020 A IL 27601020A IL 276010 A IL276010 A IL 276010A
- Authority
- IL
- Israel
- Prior art keywords
- liquid
- methods
- purifying cannabinoids
- liquid chromatography
- chromatography
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C37/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring
- C07C37/004—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by obtaining phenols from plant material or from animal material
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D11/00—Solvent extraction
- B01D11/02—Solvent extraction of solids
- B01D11/0203—Solvent extraction of solids with a supercritical fluid
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D11/00—Solvent extraction
- B01D11/02—Solvent extraction of solids
- B01D11/0288—Applications, solvents
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D11/00—Solvent extraction
- B01D11/04—Solvent extraction of solutions which are liquid
- B01D11/0492—Applications, solvents used
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
- B01D15/18—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
- B01D15/1892—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns the sorbent material moving as a whole, e.g. continuous annular chromatography, true moving beds
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D9/00—Crystallisation
- B01D9/0004—Crystallisation cooling by heat exchange
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C39/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
- C07C39/18—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring monocyclic with unsaturation outside the aromatic ring
- C07C39/19—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring monocyclic with unsaturation outside the aromatic ring containing carbon-to-carbon double bonds but no carbon-to-carbon triple bonds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C39/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
- C07C39/23—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic, containing six-membered aromatic rings and other rings, with unsaturation outside the aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/42—Separation; Purification; Stabilisation; Use of additives
- C07C51/48—Separation; Purification; Stabilisation; Use of additives by liquid-liquid treatment
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C65/01—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups
- C07C65/19—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups having unsaturation outside the aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/78—Ring systems having three or more relevant rings
- C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Botany (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Thermal Sciences (AREA)
- Crystallography & Structural Chemistry (AREA)
- Medicines Containing Plant Substances (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US15/882,516 US10207198B2 (en) | 2015-01-22 | 2018-01-29 | Methods of purifying cannabinoids using liquid:liquid chromatography |
PCT/EP2019/052069 WO2019145552A1 (en) | 2018-01-29 | 2019-01-29 | Methods of purifying cannabinoids using liquid:liquid chromatography |
Publications (1)
Publication Number | Publication Date |
---|---|
IL276010A true IL276010A (en) | 2020-08-31 |
Family
ID=65276144
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL276010A IL276010A (en) | 2018-01-29 | 2020-07-13 | Methods of purifying cannabinoids using liquid:liquid chromatography |
Country Status (9)
Country | Link |
---|---|
EP (1) | EP3746419A1 (en) |
CN (1) | CN111788171A (en) |
AU (1) | AU2019211188A1 (en) |
CA (1) | CA3089490A1 (en) |
CL (1) | CL2020001964A1 (en) |
CO (1) | CO2020009747A2 (en) |
IL (1) | IL276010A (en) |
MX (1) | MX2020007960A (en) |
WO (1) | WO2019145552A1 (en) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2020252369A1 (en) * | 2019-06-14 | 2020-12-17 | Purisys Llc | Crystalline cannabigerol |
CN110590511B (en) * | 2019-09-11 | 2021-05-28 | 上海同田生物技术股份有限公司 | Method for simultaneously separating cannabidiol and cannabigerol |
CN112279752B (en) * | 2020-10-30 | 2022-11-11 | 云南芙雅生物科技有限公司 | Supercritical carbon dioxide extraction method of cannabinoids for industrial cannabis sativa |
CN113135885A (en) * | 2021-04-07 | 2021-07-20 | 上海同田生物技术有限公司 | Method for separating and purifying tetrahydrocannabinol by high-speed counter-current chromatography |
AU2022375771A1 (en) | 2021-10-26 | 2024-05-23 | Ecofibre USA Inc. | Methods of treating ovarian cancer with hemp extract |
US11857590B2 (en) * | 2021-10-26 | 2024-01-02 | Ecofibre Limited | Systems and methods for producing hemp extracts and compositions |
AU2022379618A1 (en) | 2021-10-26 | 2024-05-23 | Ecofibre USA Inc. | Methods of treating endometriosis and other non-cancer gynecological disorders with hemp extract |
CN115385780B (en) * | 2022-08-26 | 2024-02-27 | 晨光生物科技集团股份有限公司 | Secondary cannabidiol crystal polymorph and preparation method and application thereof |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR0166088B1 (en) | 1990-01-23 | 1999-01-15 | . | Derivatives of cyclodextrins exhibiting enhanced aqueous solubility and the use thereof |
US5376645A (en) | 1990-01-23 | 1994-12-27 | University Of Kansas | Derivatives of cyclodextrins exhibiting enhanced aqueous solubility and the use thereof |
GB9518953D0 (en) | 1995-09-15 | 1995-11-15 | Pfizer Ltd | Pharmaceutical formulations |
WO2000035298A1 (en) | 1996-11-27 | 2000-06-22 | Wm. Wrigley Jr. Company | Chewing gum containing medicament active agents |
GB9711643D0 (en) | 1997-06-05 | 1997-07-30 | Janssen Pharmaceutica Nv | Glass thermoplastic systems |
ES2305437T3 (en) * | 2002-02-01 | 2008-11-01 | Resolution Chemicals Limited | DELTA-9 TETRAHIDROCANNABINOL PRODUCTION. |
US20080103193A1 (en) * | 2006-10-26 | 2008-05-01 | Trevor Percival Castor | Methods for making compositions and compositions for treating pain and cachexia |
US10155708B2 (en) * | 2015-01-22 | 2018-12-18 | Phytoplant Research S.L. | Methods of purifying cannabinoids, compositions and kits thereof |
BR122019001241B1 (en) | 2015-01-22 | 2021-05-04 | Phytoplant Research S.L | CANNABINOID PURIFICATION METHOD |
EP3061510A1 (en) | 2015-02-27 | 2016-08-31 | Bionorica Ethics GmbH | Cpc partition chromatography of cannabinoids |
BG112018A (en) * | 2015-05-22 | 2016-11-30 | "Побелч-Гле" Оод | A method for extracting a cannabinoid derivative from hemp |
-
2019
- 2019-01-29 EP EP19702843.4A patent/EP3746419A1/en active Pending
- 2019-01-29 CA CA3089490A patent/CA3089490A1/en active Pending
- 2019-01-29 WO PCT/EP2019/052069 patent/WO2019145552A1/en active Search and Examination
- 2019-01-29 MX MX2020007960A patent/MX2020007960A/en unknown
- 2019-01-29 AU AU2019211188A patent/AU2019211188A1/en not_active Abandoned
- 2019-01-29 CN CN201980015943.2A patent/CN111788171A/en active Pending
-
2020
- 2020-07-13 IL IL276010A patent/IL276010A/en unknown
- 2020-07-27 CL CL2020001964A patent/CL2020001964A1/en unknown
- 2020-08-06 CO CONC2020/0009747A patent/CO2020009747A2/en unknown
Also Published As
Publication number | Publication date |
---|---|
AU2019211188A1 (en) | 2020-07-30 |
CA3089490A1 (en) | 2019-08-01 |
WO2019145552A1 (en) | 2019-08-01 |
MX2020007960A (en) | 2020-09-24 |
CO2020009747A2 (en) | 2020-08-21 |
EP3746419A1 (en) | 2020-12-09 |
CL2020001964A1 (en) | 2020-12-18 |
CN111788171A (en) | 2020-10-16 |
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