CN212610634U

CN212610634U - Vehicle-mounted nucleic acid detection amplification and product analysis system

Info

Publication number: CN212610634U
Application number: CN202020953499.9U
Authority: CN
Inventors: 谢孝民; 李丹; 熊磊; 谢正华; 陈才夫; 袁庆明; 王兆松
Original assignee: Shanghai 3D Medicines Co Ltd
Current assignee: Shanghai 3D Medicines Co Ltd
Priority date: 2020-05-29
Filing date: 2020-05-29
Publication date: 2021-02-26
Anticipated expiration: 2030-05-29

Abstract

The utility model relates to an on-vehicle nucleic acid detects amplification and result analytic system, through the whole negative pressure laboratory that will be used for nucleic acid to detect amplification and result analysis establish on vehicle platform, can at any time as required fast migration, nimble deployment to the area of needs most, can effectively improve hot area nucleic acid detection amplification and result analytic ability through reasonable allotment, promote nucleic acid detection efficiency, need not the repeated construction negative pressure laboratory simultaneously, avoid the wasting of resources.

Description

Vehicle-mounted nucleic acid detection amplification and product analysis system

Technical Field

The utility model relates to a pathogen detection equipment technical field especially relates to an on-vehicle nucleic acid detects amplification and product analysis system.

Background

The novel coronavirus pathogen is an airborne virus pathogen with the characteristics of strong infectivity and strong pathogenicity, and often presents explosive diffusion infection in community people, thereby forming a very serious threat to the life health of people.

Because there is no specific medicine for pneumonia and other diseases caused by novel coronavirus pathogen at present, the early discovery and isolation of infected people become the most effective means for preventing and treating novel coronavirus pathogen, and the nucleic acid detection method which is most commonly used at present is a screening means which is acknowledged to be high in accuracy and reliable in result.

For a sudden epidemic situation, a large number of patients need to perform nucleic acid detection in a short time, and at the moment, the number of negative pressure laboratories in a hot spot area is insufficient, and the capabilities of nucleic acid detection amplification and product analysis cannot meet the requirements, so that the nucleic acid detection efficiency is reduced.

SUMMERY OF THE UTILITY MODEL

For solving prior art's not enough, the utility model provides an on-vehicle nucleic acid detects amplification and result analytic system, through the whole establishment of negative pressure laboratory that will be used for nucleic acid to detect amplification and result analysis on vehicle-mounted platform, provide the nucleic acid that can the quick travel deploy detect amplification and result analytic ability, can effectively improve hot spot area nucleic acid detection amplification and result analytic ability through reasonable allotment, promote nucleic acid detection efficiency, need not the repeated construction negative pressure laboratory simultaneously, avoid the wasting of resources.

In order to achieve the above object, the utility model discloses the technical scheme who adopts includes:

a vehicle-mounted nucleic acid detection, amplification and product analysis system is characterized by comprising a buffer module which is isolated from each other by a first airtight door and maintains positive pressure and a nucleic acid amplification and data analysis module which maintains negative pressure;

the buffer module comprises positive pressure equipment, a power generation device, a first airtight door connected with the nucleic acid amplification and data analysis module, an equipment door connected with the external environment and a second airtight door arranged on the equipment door;

the nucleic acid amplification and data analysis module comprises negative pressure equipment, an operation platform for placing a nucleic acid amplification and data analysis instrument and power distribution equipment electrically connected with the power generation device and/or external power supply, and the side wall of the nucleic acid amplification and data analysis module is at least provided with an airtight transmission window connected with the external environment.

Furthermore, the first airtight door and the second airtight door are rotating doors which are opened towards one side of the buffer module; the equipment door is a revolving door which is integrally opened outwards.

Furthermore, a vibration absorption connecting structure is arranged at the bottom of the operating platform; the shock absorbing attachment structure includes at least one horizontal shock absorbing spring.

Furthermore, the buffer module is also provided with a lifting platform for retracting the power generation device.

Further, the nucleic acid amplification and data analysis module further comprises a hand washing sink and a waste garbage bin.

Furthermore, the buffer module and the nucleic acid amplification and data analysis module are also provided with an ultraviolet disinfection lamp and a ventilation device.

Further, an ultraviolet disinfection lamp is arranged in the airtight transfer window.

Further, the external power supply comprises a mains interface and/or a photovoltaic power supply arranged on the top outside the system.

Further, the system also comprises an independent air conditioning device.

The utility model has the advantages that:

adopt on-vehicle nucleic acid detection amplification and product analytic system have realized establishing the complete negative pressure laboratory that has buffer module on vehicle platform, can accomplish nucleic acid detection amplification and product analytic complete flow in this system, make nucleic acid detection amplification and product analytic ability break away from the constraint of fixed laboratory, can be at any time according to needs quick travel, arrange to the area of needs most in a flexible way, make full use of current nucleic acid detection amplification and product analytic ability, reduce interim negative pressure laboratory construction pressure, be the ideal solution that should detect the demand in a large number to emergency.

Drawings

FIG. 1 is a schematic top view of an internal structure of an embodiment of the system for detecting, amplifying and analyzing nucleic acid and product of the present invention.

Fig. 2 is a schematic side view of the internal structure of the embodiment of the present invention.

Fig. 3 is a schematic rear view of an internal structure of the embodiment of the present invention.

Description of the figure numbering: 1-a buffer module, 11-positive pressure equipment, 12-a power generation device, 13-a first airtight door, 14-a second airtight door, 15-a lifting platform, 16-an equipment door, 2-a nucleic acid amplification and data analysis module, 21-negative pressure equipment, 23-an operation table, 24-power distribution equipment, 25-an airtight transfer window, 26-a hand sink, 28-a waste garbage bin, 3-an ultraviolet disinfection lamp, 4-a ventilation device, 5-a photovoltaic power supply and 6-an air conditioning device.

Detailed Description

For a clearer understanding of the present invention, reference will be made to the following detailed description of the embodiments with reference to the accompanying drawings.

Fig. 1 to fig. 3 are schematic diagrams illustrating the internal structure of an embodiment of the present invention, in which the buffer module 1 and the nucleic acid amplification and data analysis module 2 are sequentially disposed on a chassis of a van vehicle, and the buffer module 1 and the nucleic acid amplification and data analysis module 2 are completely air-tightly isolated from a cab of the vehicle to avoid contamination, although the system may also be disposed in other suitable movable structures such as a trailer box or a container. The buffer module 1 comprises a positive pressure device 11, a power generation device 12 (such as a special generator with a large-capacity lithium battery), a first airtight door 13 connected with the nucleic acid amplification and data analysis module 2, an equipment door 16 connected with the external environment, and a second airtight door 14 arranged on the equipment door 16, wherein the power generation device 12 can move out of the buffer module 1 through a lifting platform 15 when in use; the nucleic acid amplification and data analysis module 2 comprises a negative pressure device 21, an operation table 23 for placing nucleic acid amplification and data analysis instruments (such as a fluorescence PCR instrument), a hand washing pool 26, a waste garbage bin 28 and a power distribution device 24 electrically connected with the power generation device 12 and/or a commercial power and a roof photovoltaic power supply 5 for supplying power, and the side wall of the nucleic acid amplification and data analysis module 2 is at least provided with an airtight transmission window 25 connected with the external environment. Preferably, in order to reduce the influence of low-frequency vibration on the preparation of the specimen, a vibration absorption connecting structure is further arranged between the bottom of the operating platform 23 and the vehicle body, and at least one horizontal shock absorption spring is used for absorbing the vibration. The power distribution equipment 24 automatically distributes power supply for use through state monitoring of the power generation device 12 and connection conditions of commercial power and power supply of the roof photovoltaic power supply 5 and/or power supply of the vehicle engine, so that stable power supply of the system is ensured, and the system can continuously work for a long time without power supply limitation. In order to ensure that the nucleic acid amplification and data analysis process is not polluted by the external environment, the buffer module 1 and the nucleic acid amplification and data analysis module 2 are respectively manufactured by the positive pressure equipment 11 and the negative pressure equipment 21 to form a positive pressure environment and a negative pressure environment, and the first airtight door 13 and the second airtight door 14 of the revolving door structure can be closed automatically through the pressure difference between the two modules and the pressure difference between the buffer module 1 and the external environment; the equipment door 16 can adopt an integral upward-lifting structure with a rotating shaft arranged at the upper part of the door body, or an integral lateral-rotating-lifting structure with a rotating shaft arranged at the left side and the right side of the door body, and after the equipment door 16 is opened, a larger opening between the buffer module 1 and the external environment is formed, so that the entrance and exit of equipment with larger size can be met; the second airtight door 14 is a revolving door provided on the equipment door 16 and capable of being opened and closed independently, and mainly functions to allow people to enter and exit the buffer module 1. Meanwhile, in order to improve the protection effect of the system, the ultraviolet disinfection lamp 3 can be preferably arranged in the buffer module 1, the nucleic acid amplification and data analysis module 2 and the airtight transmission window 25, so that the vehicle-mounted system can be disinfected and cleaned; the buffer module 1 and the nucleic acid amplification and data analysis module 2 are also provided with an independent air interchanger 4, preferably an air interchanger with a filtering function, so that the air in the module is kept clean; the system is also provided with an independent air conditioning device 6 different from the vehicle-mounted platform, so that pollution caused by mixed air conditioning is avoided.

The lifting platform 15 is mainly provided to facilitate the entrance and exit of the power generation device 12 with a large self-weight into and out of the buffer module 1, and is particularly used for the vertical movement requirement when the power generation device 12 enters and exits from the buffer module 1. In the use process, the equipment door 16 is opened, the lifting platform 15 loaded with the power generation device 12 firstly translates to the outside of the buffer module 1, and then the whole body vertically descends to be flush with the ground of the external environment, so that the power generation device 12 can be smoothly moved to the external environment, the power generation device 12 is prevented from being carried by manpower, and the lifting platform 15 can be vertically lifted and then translated into the buffer module 1 when the power generation device 12 needs to be recovered; of course, the translation and vertical movement operations of the lifting platform 15 may be two steps performed in sequence, or may be performed together in a single movement process. The specific structure of the lifting platform 15 can refer to a vehicle-mounted wheelchair barrier-free lifting device and the like widely used in the prior art.

Use during the system, at first remove power generation facility 12 to buffer module 1 outside through lift platform 15, and preferred power generation facility 12 can remote control operation and freely remove in the certain limit, conveniently arrange the power supply line. The staff enters the buffer module 1 after passing through the second airtight door 14, and enters the nucleic acid amplification and data analysis module 2 through the first airtight door 13 after disinfecting and wearing various protective measures, so as to carry out nucleic acid amplification and data analysis operations. The required nucleic acid detection sample is transmitted by using an airtight transmission window 25 arranged on the side wall of the nucleic acid amplification and data analysis module 2, the module side window is opened to place the sample in, the module side window is closed, and after the sample is sterilized and disinfected by the ultraviolet disinfection lamp 3 in the airtight transmission window 25, an inner side window is opened by an inner side worker to take out the sample.

The buffer module 1 can provide necessary functions of changing clothes and sterilizing for people, and can also be preferably provided with a function of detecting rest of people, such as a toilet, a bathroom and the like, by utilizing a vacant position. The outside of the system can be provided with a retractable sunshade which provides more extended functions in the external environment.

On-vehicle nucleic acid detect amplification and result analytic system both can the exclusive use, also can regard as a part to use with other portable laboratory structure combinations, form the nucleic acid detection laboratory of a complete flow.

The above description is only for the preferred embodiment of the present invention, but the protection scope of the present invention is not limited thereto, and any changes or substitutions that can be easily conceived by those skilled in the art within the technical scope of the present invention are also within the protection scope of the present invention. Therefore, the protection scope of the present invention shall be subject to the protection scope of the claims.

Claims

1. A vehicle-mounted nucleic acid detection, amplification and product analysis system is characterized by comprising a buffer module which is isolated from each other by a first airtight door and maintains positive pressure and a nucleic acid amplification and data analysis module which maintains negative pressure;

2. The system of claim 1, wherein the first and second airtight doors are rotary doors that open to one side of the cushion module; the equipment door is a revolving door which is integrally opened outwards.

3. The system of claim 1, wherein the console bottom is further provided with a shock absorbing attachment structure; the shock absorbing attachment structure includes at least one horizontal shock absorbing spring.

4. The system of claim 1, wherein the buffer module is further provided with a lifting platform for housing the power generation device.

5. The system of claim 1, wherein the nucleic acid amplification and data analysis module further comprises a hand sink and a waste bin.

6. The system of claim 1, wherein the buffer module and the nucleic acid amplification and data analysis module are further provided with an ultraviolet disinfection lamp and a ventilator.

7. The system of claim 1, wherein an ultraviolet disinfection lamp is further disposed within the hermetic transfer window.

8. The system of claim 1, wherein the external power supply comprises a mains interface and/or a photovoltaic power supply disposed on top of the outside of the system.

9. The system of claim 1, further comprising a stand-alone air conditioning device.