CN210244804U

CN210244804U - Immune antibody teaching intelligent device

Info

Publication number: CN210244804U
Application number: CN201920951318.6U
Authority: CN
Inventors: Meina Lin; 林美娜; Ruiyuan Xu; 许瑞元; Wenxin Xu; 徐文鑫
Original assignee: Zhangzhou Health Vocational College
Current assignee: Zhangzhou Health Vocational College
Priority date: 2019-06-24
Filing date: 2019-06-24
Publication date: 2020-04-03
Anticipated expiration: 2029-06-24

Abstract

The utility model discloses an immune antibody teaching intelligent device includes disulfide bond and disulfide bond between a plurality of domain parts, chain, and the coded signal of memory storage domain part, the processor reads the coded signal in the memory and sends coded signal for the contact pair, and the simultaneous processing ware detects the signal of contact pair and makes the judgement, and then controls the speaker and makes sound. The inter-chain disulfide bond and the disulfide bond are used for connecting the domain parts and transmitting signals sent by the processors in the domain parts, and when the two domain parts are spliced with each other or spliced through the inter-chain disulfide bond and the disulfide bond, the processors in the domain parts receive the encoding signals of the other side and judge whether the splicing mode is correct or not, so that the loudspeaker is controlled to send corresponding sound. All domain parts assemble into immune antibody model after the correct concatenation, the utility model discloses show the structure of immune antibody model for the student with concrete material object, deepen the understanding of student to the antibody structure, make immune antibody teaching no longer abstract.

Description

Immune antibody teaching intelligent device

Technical Field

The utility model relates to a teaching mode especially relates to the teaching mode who uses during antibody teaching.

Background

The section of antibody is the central importance of basic knowledge of immunological test, the structure, functional regions and functions of each functional region of the antibody are knowledge points required to be mastered, the mastery capability of the knowledge of students in higher vocational schools is limited, the learning enthusiasm is not very high, simple characters and pictures are not vivid enough, and many students still stay in cloud after learning the antibody, so that the understanding of subsequent knowledge is influenced. The basic structure of the antibody is composed of 4 polypeptide chains, wherein the polypeptide chains are linked by disulfide bonds in different numbers to form a Y-shaped structure, the polypeptide chains are composed of two structural domains of VH, CH1, CH2, CH3, CL and VL, and interchain disulfide bonds exist in interchain parts of the structure.

In the present teaching, the basic structure of the antibody is mainly orally explained, or some PPT pictures are assisted, or drawing is performed, the structural characteristics of the antibody cannot be shown to students in a concrete image, most students can only imagine a three-dimensional antibody through the brain, but different imagination abilities are different, one antibody structure is formed by one person, although the structures are almost the same, the difference always exists, therefore, the communication between the students is inconvenient, even has errors, and even more, the students cannot recognize the antibody through a two-dimensional antibody image.

Disclosure of Invention

In order to solve the problem that the basic structure and the function of the functional region of the immune antibody are difficult to understand and master due to abstraction, and meanwhile, the interest of learning is improved, the utility model provides an intelligent device for teaching the immune antibody, which designs six structural domains of VH, CH1, CH2, CH3, CL and VL into a unified structural domain component, wherein a power supply, a memory, a processor, a loudspeaker and a plurality of contact pairs are arranged in the structural domain component, the memory stores the coding signals of the structural domain component and represents one of the six structural domains of VH, CH1, CH2, CH3, CL and VL, the processor reads the coding signals in the memory and sends the coding signals to the contact pairs, and meanwhile, the processor detects the signals of the contact pairs and makes a judgment, and then controls the loudspeaker to send sound. The inter-chain disulfide bond and the disulfide bond are used for connecting the structural domain parts and transmitting signals sent by the processors in the structural domain parts, when the two structural domain parts are spliced with each other or spliced through the inter-chain disulfide bond and the disulfide bond, the processors in the structural domain parts receive encoding signals of the other side and judge whether the splicing mode is correct, and then the speakers are controlled to send out corresponding sounds, and students are guided to correctly splice into a complete and correct immune antibody model step by step.

The utility model discloses an useful part lies in that the student assembles the domain part through the hands-on, can deepen the impression to different domain parts to deepen memory and understanding to immune antibody basic structure, make immune antibody teaching no longer abstract, let the student understand more easily and master immune antibody's basic structure and relevant knowledge, improve student's study enthusiasm.

Drawings

FIG. 1 is a diagram of a domain component structure;

FIG. 2 is a schematic diagram of a built-in circuit of a domain component and its elements;

FIG. 3 is a schematic of interchain disulfide bond structure and circuit;

FIG. 4 is a disulfide bond structure and a schematic circuit diagram;

FIG. 5 is a diagram showing the basic structure of an immune antibody.

Detailed Description

The basic structure of the immune antibody comprises six domains of VH, CH1, CH2, CH3, CL and VL, as well as interchain disulfide bonds and disulfide bonds for connecting different domains, wherein the six domains are arranged in a specific way and are connected by the interchain disulfide bonds and disulfide bonds to form a Y-shaped structure, in order to enable students to better understand the basic structure of the immune antibody through a splicing way, the embodiment designs the six domains of VH, CH1, CH2, CH3, CL and VL into uniform domain parts, and the different domain parts are distinguished through labels.

Domain component structure diagram as shown in fig. 1 domain component 1 comprises a label 101, a number of notches 102 and a flange 103. The label 101 is indicated by one of the six domain labels VH, CH1, CH2, CH3, CL and VL for distinguishing between the different domains in the design of the uniform domain component 1. A plurality of notches 102 and flanges 103 are arranged around the structure domain part 1, the flanges 103 and the notches 102 are in concave-convex matching, and the flanges 103 can be inserted into the notches 102, so that butt joint between the structure domain parts 1 is facilitated, and the function of fastening the structure domain parts can be achieved.

As shown in the schematic diagram of the circuitry and its components within the domain part of fig. 2, the power supply 109, the memory 107, the processor 106, the speaker 108 and the contact pairs 110 are provided within the domain part 1. The power supply 109 supplies the power required by the processor 106, memory 107 and speaker 108. The contact pairs 110 are disposed within the notches 102 and flanges 103 shown in fig. 1, and each notch 102 and flange 103 has a corresponding contact pair 110. The memory 107 stores encoded signals of the domain unit 1 representing one of the six domains VH, CH1, CH2, CH3, CL and VL, which encoded signals can be read from the memory 107 by the processor 106, transmitted to the other domain unit 1 via the pair of contacts 110 connected to the processor, and finally received by the processor 106 in the other domain unit 1. After receiving the coding signals sent by other domain components 1, the processor 106 combines the coding signals to receive the coding signals from the contact pair 110 of the notch 102 or the flange 103, and comprehensively judges whether the splicing between the domain components is correct, if the splicing is correct, the processor 106 controls the loudspeaker 108 to send out a prompt tone indicating that the splicing is correct, if the splicing is incorrect, the processor 106 controls the loudspeaker 108 to send out a prompt tone indicating that the splicing is failed, and students try to splice the domain components 1 marked by other labels again.

As shown in the inter-chain disulfide bond structure and the schematic circuit diagram of FIG. 3, the inter-chain disulfide bond 2 shows a linear shape provided with two flanges 103 and two contact pairs 110. The contact pairs 110 are disposed within the flanges 103, and each flange 103 has a corresponding contact pair 110. There is a circuit connection between the two contact pairs 110. The flange 103 of the interchain disulfide bond 2 can be inserted into any one of the notches 102 in the domain part 1 as shown in FIG. 1, while the pair of contacts 110 in the interchain disulfide bond 2 and the pair of contacts 110 in the domain part 1 contact each other to form a circuit connection that functions to transfer the encoded signal between the domain parts 1.

As shown in FIG. 4, which is a schematic diagram of the disulfide bond structure and circuit, disulfide bond 3 shows an "H" shape, which is provided with four flanges 103 and four contact pairs 110. The contact pairs 110 are disposed within the flanges 103, and each flange 103 has a corresponding contact pair 110. The four flanges 103 in the disulfide bond 3 are located at the four corners of the "H" shape, one set of two flanges 103 on the left side with circuit connections between their corresponding two contacts 110, and similarly, another set of two flanges 103 on the right side with circuit connections between their corresponding two contacts 110. The flange 103 of the disulfide bond 3 can be inserted into any one of the notches 102 in the domain part 1 as shown in fig. 1, while the pair of contacts 110 in the disulfide bond 3 and the pair of contacts 110 in the domain part 1 contact each other to form a circuit connection which functions to transfer the encoded signal between the domain parts 1.

As shown in FIG. 5, the basic structure of the immune antibody 100 has twelve domain members 1, two interchain disulfide bonds 2 and one disulfide bond 3. The tag 101 of the domain component 1 is labelled with VH, CH1, CH2, CH3, CL and VL symbols, two each, representing two each of the six domains VH, CH1, CH2, CH3, CL and VL, for a total of twelve domains. The domain parts 1, interchain disulfide bonds 2 and disulfide bonds 3 with different tag symbols represent successful completion of the splicing of the basic structure of the immune antibody when they form a specific arrangement as shown in FIG. 3. When the students continuously try to splice, the processor 106 in the domain component 1 continuously judges, and the loudspeaker 108 is used for prompting correctness or failure, so that the students are prompted to correctly splice the adjacent domain components 1 connected through the inter-chain disulfide bond 2/disulfide bond 3, the students are guided to finish the splicing of the basic structure of the immune antibody step by step, when the splicing is finished, the processors 106 in all the domain components 1 are communicated through the contact pairs 110, whether the number of the domain components 1 is correct or not and whether the mutual direct position relation is correct or not are judged, and if the two are correct, the processor 106 controls the loudspeaker 108 to send out a prompt sound for successful splicing of the basic structure of the immune antibody.

In this embodiment, the students are guided to complete successful splicing of the basic structure model 100 of the immune antibody step by manually splicing the domain component 1 and prompting correct or failed in the splicing process of the domain component 1, so that the learning enthusiasm of the students is improved, the teaching of the immune antibody is not abstract any more, the students can understand and master the basic structure and related knowledge of the immune antibody more easily, and the students can deepen the memory and understanding of the basic structure of the immune antibody.

The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention, and various modifications and changes may be made by those skilled in the art. Any modification, equivalent replacement, or improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims

1. An intelligent immune antibody teaching device is characterized by comprising a plurality of domain components (1), interchain disulfide bonds (2) and disulfide bonds (3);

the structure domain component (1) is internally provided with a power supply (109), a memory (107), a processor (106), a loudspeaker (108) and a plurality of contact pairs (110), the power supply (109) provides electric energy required by the processor (106), the memory (107) and the loudspeaker (108), the memory (107) stores a coded signal of the structure domain component (1), the processor (106) reads the coded signal in the memory (107) and sends the coded signal to the contact pairs (110), and meanwhile, the processor (106) detects the signal of the contact pairs (110) and makes a judgment so as to control the loudspeaker (108) to emit sound;

the inter-chain disulfide bond (2) is provided with two contact pairs (110) which are communicated with each other;

the disulfide bond (3) is provided with two groups of four contact pairs (110) which are communicated with each other;

the interchain disulfide bond (2) and disulfide bond (3) are used to link the domain component (1), transmit signals from the processor (106) in the domain component (1), and assemble the basic structure of the immune antibody (100).

2. An intelligent immune antibody teaching device according to claim 1, wherein the domain unit (1) further comprises a tag (101), a plurality of notches (102) and a flange (103), the tag (101) being affixed to the outside of the domain unit (1), the tag (101) being capable of identifying one of "VL", "VH", "CL", "CH 1", "CH 2" and "CH 3"; the notch (102) and the flange (103) are arranged around the domain parts (1), and the flange (103) can be inserted into the notch (102) for connection between the domain parts (1).

3. An intelligent immune antibody teaching device according to claim 2, wherein the inter-chain disulfide bond (2) is further provided with two flanges (103), the flanges (103) being insertable into any one of the notches (102) in the domain members (1) for connection of the domain members (1).

4. An intelligent immune antibody teaching device according to claim 2, wherein the disulfide bond (3) is further provided with four flanges (103), the flanges (103) being insertable into any one of the notches (102) in the domain members (1) for connection of the domain members (1).