CN109124588A - A kind of OCT probe for mouth disease inspection - Google Patents

A kind of OCT probe for mouth disease inspection Download PDF

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Publication number
CN109124588A
CN109124588A CN201811118854.4A CN201811118854A CN109124588A CN 109124588 A CN109124588 A CN 109124588A CN 201811118854 A CN201811118854 A CN 201811118854A CN 109124588 A CN109124588 A CN 109124588A
Authority
CN
China
Prior art keywords
probe
connecting sleeve
probe body
oct
cable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201811118854.4A
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Chinese (zh)
Inventor
侯方
张慕阳
梁艳梅
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Nankai University
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Nankai University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nankai University filed Critical Nankai University
Priority to CN201811118854.4A priority Critical patent/CN109124588A/en
Publication of CN109124588A publication Critical patent/CN109124588A/en
Pending legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0062Arrangements for scanning
    • A61B5/0066Optical coherence imaging
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0082Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes
    • A61B5/0088Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes for oral or dental tissue

Abstract

The invention discloses a kind of OCT probe for mouth disease inspection, including probe body, connecting sleeve, probe handle, single mode optical fiber, focusing mirror, scanning reflection mirror module, optical window, lighting source, cable one and cables two.Probe body is sequentially connected with connecting sleeve, probe handle, single mode optical fiber passes through probe handle, connecting sleeve, end is fixed in probe body, focusing mirror, scanning reflection mirror module are fixed in probe body, optical window is embedded in probe body upper front end, and the cable one, cable two pass through probe handle, connecting sleeve enters probe body.This probe, which is capable of providing lighting condition and is easy to medical staff, directly observes oral mucosa affection, and can be by scanning the two-dimentional or three-dimensional OCT indagation realized to oral cavity mucous membrane tissue, reflective focus method reduces the influence using the issuable optical aberration of refracting element to OCT image quality.The probe convenient and flexible operation, is easy to grasp.

Description

A kind of OCT probe for mouth disease inspection
Technical field
This disclosure relates to medical imaging devices field more particularly to a kind of OCT probe for mouth disease inspection.
Background technique
Optical coherence tomography (Optical Coherence Tomography, OCT) is a kind of high-resolution optical Imaging technique.It is based on low-coherent light principle of interference, is believed by detecting the dim light that different depth layer is reflected back from biological tissue Biological tissue's microstructure is detected in number realization.The two dimensional image or three-dimensional of sample are obtained by incident light direction deflection scanning Image.OCT technology has lossless, high-resolution, high speed, the advantage of high sensitivity, can be realized to biological tissue in body and Real-time detection.In recent ten years, OCT technology is rapidly developed, currently, by clinical application in eyes and angiocarpy etc. In medical diagnosis on disease, a large amount of preclinical phase researchs are also carried out in fields such as skin, alimentary canal, oral cavities.
The inspection of mouth disease is one of important applied field of OCT technology.Due to oral cavity structure complexity, tooth, tongue The presence of equal organs directly observe to cavity interior lesion locations using traditional desk-top OCT system to be inconvenient, Therefore the OCT probe that research and development are suitable for mouth disease inspection has great importance.
It is suitable for the OCT probe of mouth disease inspection in the prior art, the OCT for being mostly common to the open cavity of human body is visited Head.In terms of mechanical structure, mostly use straight pipe type structure, by probe pipe in optical element realize before to or side direction light Scanning imagery, the observation of this structure lesion locations many for cavity interior is simultaneously inconvenient, such as gum, the mouth of Its pulp The mucous membrane etc. of chamber side deep place.In terms of imaging optical path, the OCT probe with scanning imagery ability of the prior art is equal Realize the focusing of light beam using refraction optical element, and refracting element is there are optical aberration and chromatic dispersion problem, will affect OCT at Image quality amount.
Summary of the invention
For overcome the deficiencies in the prior art, present disclose provides a kind of OCT probe applied to mouth disease inspection, Easily the OCT images of two and three dimensions can be carried out by the intracavitary different location of counterpart.The technical solution of the disclosure is as follows:
A kind of OCT probe for mouth disease inspection, including probe body, connecting sleeve, probe handle, single-mode optics Fibre, focusing mirror, scanning reflection mirror module, optical window, lighting source, cable one and cable two, it is characterised in that: described Probe body is sequentially connected with connecting sleeve, probe handle;The single mode optical fiber passes through probe handle, connecting sleeve, and end is solid Due in probe body, the focusing mirror, scanning reflection mirror module are fixed in probe body, and the optical window is embedded in Probe body upper front end, the single mode optical fiber, focusing mirror, scanning reflection mirror and optical window collectively form OCT scan Imaging optical path focuses on after the light beam line focus focusing mirror and plane magnifier module of the single mode optical fiber outgoing reflect Optical window outer edge;The lighting source is fixed on probe body optical window and shines in the following, providing guiding performance for probe detection It is bright;The cable one, cable two pass through probe handle, connecting sleeve and enter probe body, the cable one be lighting source and Scanning reflection mirror module for power supply, the cable two provide scanning signal for scanning reflection mirror module.
Wherein, the probe body is three-axial ellipsoid structure, and the connecting sleeve, probe handle are hollow tubular knot Structure.
Wherein, the probe body and connecting sleeve, connecting sleeve and probe handle are solid by mechanical structure or binder Fixed connection.
Wherein, the connecting sleeve can be using probe handle as polar axis 120-180 degree range inner bending.
Wherein, the focusing mirror is concave mirror, is connect with probe body shell by binder.
Wherein, the scanning reflection mirror module includes plane mirror and scanning means, scanning means be MEMS, Galvanometer or micromotor, plane mirror can carry out one-dimensional or two-dimensional directional scanning under scanning means driving.
Wherein, the material of the optical window is clear optical glass or resin, is connected with probe body by binder It connects.
The disclosure can be convenient the ground intracavitary different location of counterpart by the bending of the connection structure and connecting sleeve of three-stage It is detected, the introducing of lighting source is more convenient for operator to use.Pass through built-in focusing mirror and scanning reflection mirror Module cooperates the OCT image that two and three dimensions may be implemented, while reducing the loss and refraction of the light as caused by refraction The light wave dispersion that original part introduces, optimizes focusing and imaging effect.
Detailed description of the invention
Fig. 1 is a kind of structural schematic diagram of OCT probe for mouth disease inspection of the disclosure.
Fig. 2 is a kind of side diagrammatic cross-section of OCT probe for mouth disease inspection of the disclosure.
Fig. 3 is that OCT image optical path is illustrated in a kind of probe body of OCT probe for mouth disease inspection of the disclosure Figure.
In figure, 1, probe body, 2, connecting sleeve, 3, probe handle, 4, single mode optical fiber, 5, focusing mirror, 6, scanning Magnifier module, 7, optical window, 8, lighting source, 9, cable one, 10, cable two.
6-1, plane mirror, 6-2, scanning means.
Specific embodiment
Explanation and specific embodiment further illustrate the disclosure with reference to the accompanying drawing.
As shown in Figure 1 and Figure 2, a kind of OCT probe for mouth disease inspection of the disclosure, including probe body 1, even Female connector pipe 2, probe handle 3, single mode optical fiber 4, focusing mirror 5, scanning reflection mirror module 6, optical window 7, lighting source 8, Cable 1 and cable 2 10.The probe body 1 is sequentially connected with connecting sleeve 2, probe handle 3;The single mode optical fiber 4 is worn Probe handle 3, connecting sleeve 2 are crossed, end is fixed in probe body 1, and the focusing mirror 5, scanning reflection mirror module 6 are solid Due in probe body, the optical window 7 is embedded in 1 upper front end of probe body, the single mode optical fiber 4, focusing mirror 5, Scanning reflection mirror module 6 and optical window 7 collectively form OCT scan imaging optical path, and the light beam that the single mode optical fiber 4 is emitted is through poly- Burnt reflecting mirror 5 is focused with after the reflection of plane magnifier module 6, focuses on 7 outer edge of optical window;The lighting source 8 is fixed In 1 optical window 7 of probe body in the following, providing guiding performance illumination for probe detection.The cable 1, cable 2 10, which pass through, to be visited Head handle 3, connecting sleeve 2 enter probe body 1, and the cable 1 is that lighting source 8 and scanning reflection mirror module 6 are powered, institute Stating cable 2 10 is that scanning reflection mirror module 6 provides scanning signal.
In the present embodiment, the probe body 1 is three-axial ellipsoid structure, during the connecting sleeve 2, probe handle 3 be Hollow tube-like structure, the probe body 1, probe handle 3 are medical plastic material, and the connecting sleeve 2 is medical organic silicon bullet Property body material, the probe body 1 and connecting sleeve 2, connecting sleeve 2 and probe handle 3 are solid by mechanical structure or binder Fixed connection, the connecting sleeve 2 can be that polar axis 120-180 degree encloses inner bending with probe handle 3.
In the present embodiment, the focusing mirror 5 is concave mirror, is connected with 1 shell of probe body by binder It connects;
In the present embodiment, the scanning reflection mirror module 6 includes plane mirror 6-1 and scanning means 6-2, in this implementation Scanning means 6-2 is biaxial MEMS MEMS in example, and plane mirror 6-1 can be under the driving of scanning means 6-2 The scanning of row two-dimensional directional.
In the present embodiment, the optical window 7 is transparent optical resin, is connect with probe body 1 by binder.
In the present embodiment, the lighting source 8 is LED light source.
As shown in figure 3, the light beam that the single mode optical fiber 4 is emitted, exposes to 5 surface of focusing mirror, line focus reflecting mirror 5 Become converging beam after focusing reflection, then focuses on optical window after the plane mirror 6-1 of scanning reflection mirror module 6 reflection 7 outer ledges.Plane mirror 6-1 does two-dimensional deflection under the driving of scanning means 6-2, and beam focusing position can be in optical window Scanning movement in 7 ranges of mouth.When in use, optical window 7 is aligned and checks position by the bootable operator of lighting source 8, then Optical window 7 is contacted and checks position, the back-reflection light in oral cavity tissue can return in OCT system along probe optical path, complete Imaging, with the observation and diagnosis for mouth disease.

Claims (7)

1. a kind of OCT probe for mouth disease inspection, including probe body, connecting sleeve, probe handle, single mode optical fiber, Focusing mirror, scanning reflection mirror module, optical window, lighting source, cable one and cable two, it is characterised in that:
The probe body is sequentially connected with connecting sleeve, probe handle;
The single mode optical fiber passes through probe handle, connecting sleeve, and end is fixed in probe body, and the focusing mirror is swept It retouches magnifier module to be fixed in probe body, the optical window is embedded in probe body upper front end, and the single mode optical fiber gathers Burnt reflecting mirror, scanning reflection mirror and optical window collectively form OCT scan imaging optical path, the light beam warp of the single mode optical fiber outgoing Focusing mirror is focused with after the reflection of plane magnifier module, focuses on optical window outer edge;
The lighting source is fixed on probe body optical window in the following, providing guiding performance illumination for probe detection;
The cable one, cable two pass through probe handle, connecting sleeve and enter probe body, the cable one be lighting source and Scanning reflection mirror module for power supply, the cable two provide scanning signal for scanning reflection mirror module.
2. the OCT probe according to claim 1 for mouth disease inspection, it is characterised in that: the probe body is Three-axial ellipsoid structure, the connecting sleeve, probe handle are hollow tubular structure.
3. the OCT probe according to claim 1 for mouth disease inspection, it is characterised in that: the probe body with Connecting sleeve, connecting sleeve are fixedly connected with probe handle by mechanical structure or binder.
4. the OCT probe according to claim 1 or 3 for mouth disease inspection, it is characterised in that: the connecting sleeve It can be using probe handle as polar axis 120-180 degree range inner bending.
5. the OCT probe according to claim 1 for mouth disease inspection, it is characterised in that: the focusing mirror For concave mirror, it is connect with probe body shell by binder.
6. the OCT probe according to claim 1 for mouth disease inspection, it is characterised in that: the scanning reflection mirror Module includes plane mirror and scanning means, and scanning means is MEMS, galvanometer or micromotor, plane mirror One-dimensional or two-dimensional directional scanning can be carried out under scanning means driving.
7. the OCT probe according to claim 1 for mouth disease inspection, it is characterised in that: the optical window Material is clear optical glass or resin, is connect with probe body by binder.
CN201811118854.4A 2018-09-25 2018-09-25 A kind of OCT probe for mouth disease inspection Pending CN109124588A (en)

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Application Number Priority Date Filing Date Title
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CN111990975A (en) * 2020-09-09 2020-11-27 南京诺源医疗器械有限公司 Infrared tumor imaging system and method
CN114786572A (en) * 2020-11-04 2022-07-22 上海交通大学医学院附属瑞金医院 Parallel detection and/or hook type optical fiber transmission microcirculation monitoring device
CN115429215A (en) * 2022-11-09 2022-12-06 北京犀燃科技有限公司 Intraocular OCT optical fiber probe

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CN106932398A (en) * 2017-03-13 2017-07-07 哈尔滨工程大学 A kind of shadowgraph imaging system for the spraying measurement of many spray orifices
CN107019488A (en) * 2016-08-17 2017-08-08 深圳英美达医疗技术有限公司 A kind of OCT probe and its manufacture method
CN108523849A (en) * 2018-05-02 2018-09-14 南开大学 Based on autofluorescence technology and the classification of the thyroid gland neck tissue of optical coherence tomography and identifying system and method

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WO2011100984A1 (en) * 2010-02-17 2011-08-25 El-Sayed Ameen Mahmoud Rezq Gelatin, a curcumin drug carrier system
CN202699100U (en) * 2012-07-20 2013-01-30 深圳市斯尔顿科技有限公司 Hand-held optical coherence tomography (OCT) probe and OCT measurement system
CN103040429A (en) * 2013-01-05 2013-04-17 无锡微奥科技有限公司 Optical image detection device for oral cavity and imaging method
CN104076022A (en) * 2014-07-07 2014-10-01 北京理工大学 Portable raman spectrometer using concave grating
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CN111990975A (en) * 2020-09-09 2020-11-27 南京诺源医疗器械有限公司 Infrared tumor imaging system and method
CN114786572A (en) * 2020-11-04 2022-07-22 上海交通大学医学院附属瑞金医院 Parallel detection and/or hook type optical fiber transmission microcirculation monitoring device
CN114786572B (en) * 2020-11-04 2023-08-18 上海交通大学医学院附属瑞金医院 Parallel detection and/or hook type optical fiber transmission microcirculation monitoring device
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CN115429215B (en) * 2022-11-09 2023-03-24 北京犀燃科技有限公司 Intraocular OCT optical fiber probe

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