CN103040429A - Optical image detection device for oral cavity and imaging method - Google Patents
Optical image detection device for oral cavity and imaging method Download PDFInfo
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Abstract
The invention discloses an optical image detection device for an oral cavity and an imaging method. The optical image detection device for an oral cavity comprises a scanning imaging device integrated with an OCT (optical coherence tomography) scanning imaging system and a visual imaging system. The scanning imaging device is used for acquiring real video images of the sample tissues and two-dimensional and three-dimensional optical tomography images in the target area in real time. With OCT images and visual images combined, not only the real video images of the oval cavity tissues but also the two-dimensional and three-dimensional optical tomography images are acquired in real time, and the acquired images are of micron high resolution. The optical image detection device for an oral cavity is capable of providing enough and rich sample tissue information to doctors, thereby providing doctors with basis for accurate diagnosis of pathology.
Description
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Technical field
The present invention relates to a kind of hand-held optical scanner based on the MEMS micro mirror, relate in particular to a kind of optical image checkout gear and formation method for the oral cavity.
Background technology
Oral cancer is to occupy the 6th normal tumor in the whole world, can betide tongue, cheek, jawbone, any position of periodontal tissue.Male's incidence rate is high 1 to 5 times than the women.In developing country, oral cancer is a large problem.The incidence rate of oral cancer is relevant with the increase at age.Incidence rate sharply rises after 40 years old.Along with the world aged's increase, will there be more old people to be among the highly dangerous that oral cancer occurs.Its danger is sharply risen with age growth, 80-10 ten thousand when rising to 60 years old by 30 years old male's 7-10 ten thousand.Smoking and to drink be the topmost risk factor that causes oral cancer.The danger of suffering from oral cancer is along with the year number and increasing of the number of smoking every day and smoking.The increase of oral cancer incidence rate and the consumption of wine are proportional.
Along with the development of OCT technology, it has been widely used in detection diagnosis of ophthalmology and skin class disease, but not yet has checkout gear more flexibly to can be used for the detection of organ-tissue in the human body, mainly is hampered by the small and exquisite of OCT imaging system sample arm.The scanning micro-mirror of micro electro mechanical system (MEMS) technology (microelectromechanical systems, be called for short MEMS) being combined with the OCT technology carry out the exploitation of OCT imaging system, is one of patent application unit's emphasis development project.One of inventor applies for that patent of invention description 201210322636.9 discloses a kind of OCT endoscopic imaging device, and this imaging device has adopted the MEMS scanning micro-mirror to realize the scan function of sample arm, is a kind of effective OCT based endoscopic imaging detection method.Utilize the OCT scan-image to analyze several parameters, comprise strength criterion deviation, spatial spectral distribution and epithelial thickness etc., can differentiate in real time the stages of oral precancerous lesion, also can be with OCT scanning result and section pathology image analysing computer relatively, for the analysis of pathology provides diagnosis basis.The present invention will provide a kind of optical image detection system for the oral cavity, not only can satisfy the OCT imaging and detect needs, can also real-time positioning, so that the doctor accurately finds diseased region.
The scanned imagery device flexible structure is various, not only can hand use, can also be fixed on the support, utilizes the multiple degrees of freedom of support that inserting end is carried out position and angular adjustment, can be used for oral cavity sequestered tissue or is difficult for the close scanning imagery of organizing.
According to the difference setting of MEMS micro mirror in scanned imagery device, can realize that scanned imagery device carries out scanning imagery in multiple direction and different angles in addition, comprise side direction scanning imagery, forward direction or the imaging of side scan forward and the imaging of ring circumferential scanning.Greatly improve the subject range of this scanned imagery device, not only can be used for the oral cavity, also can be used for the scanning imagery of other more shallow tract or pipeline.
Summary of the invention
The present invention seeks to for the OCT optical image technology is applied to the pathological change of oral cavity diagnosis and detection, and annex simultaneously the function of video image, can be used for auxiliary detection and the diagnosis of early lesion in the oral cavity, accurate biopsy sampling and surgical navigational, and the clinical practice such as monitoring after operation.The present invention is mainly used in the noinvasive of oral cavity soft or hard tissue, in real time, high resolution three-dimensional imaging, its resolution is up to 1～10 micron, can effectively tell majority and come from and organize the following 2-3 millimeter in top layer, early cancer's cell of several microns sizes in the epithelial tissue.The early lesion that can be applicable to the organ-tissues such as tooth, oral mucosa, tongue detects.Optical imaging apparatus of the present invention has not only solved visual pattern can not obtain the problem of pathological tissues faultage image, and radiation risk and the not high defective of resolution of having avoided the X-ray photographic imagery to bring.
The present invention adopts following technical scheme for achieving the above object: a kind of optical image checkout gear for the oral cavity comprises the scanned imagery device that is integrated with OCT scanning imaging system and Vision imaging system; Described scanned imagery device is used for obtaining in real time the real video image of oral cavity tissue and two dimension, the three-dimensional optical faultage image of target area.
Further, described scanned imagery device comprises handle, the inserting end with optic electric interface and is located at MEMS scanheads and imageing sensor in the described inserting end; The outfan of described MEMS scanheads be connected the outfan of imageing sensor and be connected with described optic electric interface respectively; The areas imaging of described imageing sensor comprises the transversal scanning scope of MEMS scanheads.
Further, described OCT scanning imaging system comprises light source, optical fiber, blender, reference arm, detector, data acquisition and processing module, drives panel, CPU, display unit and is located at the interior MEMS scanheads of described scanned imagery device; Described light source is sent to data acquisition and processing module with triggering signal, simultaneously light signal is delivered to blender by optical fiber transmission, and the hybrid light source that obtains after the blender light-splitting processing is sent to respectively reference arm and MEMS scanheads; The interference signal that the two-way light that another outfan of described blender will form through the light that the sample diffuse scattering is returned produces is input to detector, and after this detector difference processing, be input to described data acquisition and processing module, the signal of telecommunication after described data acquisition and processing module will be processed is delivered to CPU and is carried out image processing and recovery, and the OCT image that forms at last is presented on the display unit; Wherein, described driving panel input is connected with described CPU, and its outfan connects respectively the MEMS micro mirror drive end of described data acquisition and processing module and MEMS scanheads; Described Vision imaging system comprises the imageing sensor of being located in the described scanned imagery device, the real time imaging of described image sensor senses sample also sends to described data acquisition and processing module by opto-electronic conversion, the signal of telecommunication after described data acquisition and processing module will be processed is sent to CPU and carries out image processing and recovery, and the vision imaging that forms at last is presented on the display unit.
Further, the inserting end of described scanned imagery device can be realized side direction scanning or scan forward or side scan forward or ring circumferential scanning.
Further, the driving signal of described MEMS scanheads and described imageing sensor carry out signal transmission control by wired or wireless RF-wise and system.
Further, when the inserting end of described scanned imagery device is the ring circumferential scanning, make outgoing beam do circular scanning or oval scanning or track type scanning or are scan by driving panel control MEMS micro mirror actuating arm, and obtain the optical ring faultage image in conjunction with the OCT imaging system.
Further, described scanned imagery device is arranged to hand-held or is arranged to multiple degrees of freedom bridge method of clamping and carries out work.
Further, the inserting end of described scanned imagery device adopts the warp architecture of being convenient to oral cavity different tissues scanning imagery.
Further, described MEMS micro mirror adopts electrothermal drive or static driving or Electromagnetic Drive or Piezoelectric Driving.
Further, described MEMS micro mirror is made of minute surface, frame and four actuating arms that are coated with optical coating, actuating arm is uniform to be arranged at around minute surface and the frame, be provided with the pad that connects for conduction in described frame lower end, described actuating arm adopts multilayer material to form, apply voltage to described actuating arm heating or heat release, its material production expands or shrinks, and does yaw motion thereby drive minute surface.
A kind of optical image checkout gear and formation method for the oral cavity, described method comprises the steps:
1) sends to described data acquisition and processing module through opto-electronic conversion behind the real image of image sensor senses sample, the signal of telecommunication after described data acquisition and processing module will be processed is sent to CPU and carries out image processing and recovery, and the video image that forms at last is presented on the display unit;
2) light source is sent to data acquisition and processing module with triggering signal, simultaneously light signal is sent to blender, is sent to respectively reference arm and sample arm after the blender light-splitting processing, i.e. the MEMS scanheads;
3) light beam irradiates that penetrates from the MEMS scanheads is on sample, and the light that the light that sample is returned along the diffuse scattering of the certain thickness the exterior and the interior layer of depth direction and reference arm reflect interferes in blender;
4) interference light is transformed into interference signal through detector, interference signal is input to data acquisition and processing module and CPU after the detector difference processing, by the interference signal after the difference processing is carried out Fourier transformation, obtain sample along the certain thickness tomographic map of depth direction;
5) by the MEMS micro mirror that drives in the panel control OCT imaging probe one dimension or two-dimensional scan are carried out in the target area in the video image region, and at each scanning element repeating step 3)-4), obtain the two and three dimensions tomographic map of target area tissue, itself and video image show by display unit in the lump.
Beneficial effect of the present invention: (1) combines the OCT image with visual pattern, both can obtain in real time the real video image of sample tissue, can also obtain in real time two dimension, the three-dimensional optical faultage image of target area, and the high-resolution with several micron levels, can provide enough abundant sample tissue information to the doctor as the oral cavity image checkout gear, for the doctor provides foundation to the Accurate Diagnosis of pathology.
(2) by optical image checkout gear of the present invention, can can't harm and noninvasive the various suspected lesion tissues in oral cavity accurately be scanned to obtain its optical section, thereby can replace biological tissue's sampling and section before the art, greatly alleviate patient's misery and shorten detection time.
(3) adopted the MEMS scanheads in view of scanned imagery device of the present invention, so that endoscope's inserting end diameter is enough little, and structure is light and handy, can use flexibly.
(4) by 4 kinds of scan modes of MEMS scanheads of the present invention, but scan detection according to pathological tissues present position flexible choice scanned imagery device, can adopt suitable scanheads carry out scanning imagery for different target areas.
(5) by scanned imagery device of the present invention, can directly hand use, handle can design according to ergonomic features, also can use by the multi-joint bracing frame is fixing, and is flexible and convenient to use, is convenient to dismounting and assembling, and is convenient to safeguard;
(6) the present invention adopts electrothermal drive MEMS micro mirror, and low-power, small voltage drive, the two-dimensional scan shape is flexible, use safety, and structure is small and exquisite.
Description of drawings
Fig. 1 optical image structure of the detecting device of the present invention schematic diagram;
Fig. 2 scanned imagery device structural representation of the present invention;
Fig. 3 scanned imagery device side direction scanning of the present invention inserting end schematic diagram;
Fig. 4 scanned imagery device scan forward of the present invention inserting end schematic diagram;
Fig. 5 scanned imagery device side of the present invention scan forward inserting end schematic diagram;
Fig. 6 scanned imagery device ring of the present invention circumferential scanning inserting end;
Fig. 7 OCT ring of the present invention circumferential scanning imaging shape of cross section;
Fig. 8 MEMS micro-mirror structure of the present invention schematic diagram;
Structural representation when Fig. 9 scanned imagery device of the present invention is multiple degrees of freedom bridge method of clamping;
Figure 10 scanned imagery device of the present invention is the handheld structure schematic diagram.
The specific embodiment
Shown in Figure 1, for a kind of optical image checkout gear for the oral cavity, comprise the scanned imagery device 103 that is integrated with OCT scanning imaging system and Vision imaging system; Described scanned imagery device 103 is used for obtaining in real time the real video image of sample tissue and two dimension, the three-dimensional optical faultage image of target area.
Described OCT scanning imaging system comprises light source, blender, reference arm, detector, data acquisition and processing module, drive panel CPU, display unit and be located at MEMS scanheads 102 in the described scanned imagery device 103; Described light source is sent to data acquisition and processing module with triggering signal 106, simultaneously light signal is sent to blender, and the hybrid light source that obtains after the blender light-splitting processing is sent to respectively reference arm and MEMS scanheads 102; The interference signal that the two-way light that another outfan of described blender will form through the light that the sample diffuse scattering is returned produces is input to detector, and after this detector difference processing, be input to described data acquisition and processing module, the signal of telecommunication after described data acquisition and processing module will be processed is delivered to CPU and is carried out image processing and recovery, and the OCT image that forms at last is presented on the display unit; Wherein, described driving panel input is connected with described CPU, and its outfan connects respectively the MEMS micro mirror drive end of described data acquisition and processing module and MEMS scanheads 102; Described Vision imaging system comprises the imageing sensor 101 of being located in the described scanned imagery device 103, described imageing sensor 101 is responded to the real time imaging of samples and is obtained video signal 105 by opto-electronic conversion, then send to described data acquisition and processing module, the signal of telecommunication after described data acquisition and processing module will be processed is sent to CPU and carries out image processing and recovery, and the vision imaging that forms at last is presented on the display unit.By R, G, B delivery outlet or video output, show through display unit, can obtain clear amplification, real sample surfaces image.Obtain the real image zone of samples by imageing sensor 101, can adopt MEMS scanheads 102 to carry out optical scanning to interested zone wherein simultaneously, can obtain the OCT imagery zone of sample.The areas imaging of described imageing sensor comprises the transversal scanning scope of MEMS scanheads; Provide positioning function for the OCT imaging region simultaneously.Display unit is visual pattern and the OCT image of show sample simultaneously.
Among Fig. 2, described scanned imagery device comprises handle 202, the inserting end 203 with optic electric interface and is located at MEMS scanheads 204, imageing sensor 205 in the described inserting end 203; The outfan of described MEMS scanheads 204 be connected the outfan of imageing sensor 205 and be connected with described optic electric interface 201 respectively.Optic electric interface 201 is arranged at handle 202 tail ends, and the optical fiber that is connected with MEMS scanheads 204 and electric connection line are installed on respectively handle 202 and inserting end 203 inside, is respectively applied to the light transmission and drives the path for MEMS provides electricity.MEMS scanheads 204 and imageing sensor 205 are arranged at the inserting end 203(elongated end of scanning means by light, mechanical, electrical designing requirement, stretch into the oral cavity part), imageing sensor 205 is communicated with optic electric interface by the electric connection line that is arranged at scanning means inside.The driving signal of described MEMS scanheads and described imageing sensor 205 can carry out signal transmission control by wireless radio frequency mode and system.
The inserting end detailed structure as shown in Figure 3, it can adopt warp architecture, is convenient to the scanning imagery to the oral cavity different tissues.Inserting end inside comprises MEMS scanheads and imageing sensor 308.The MEMS scanheads comprises MEMS micro mirror 309, optical fiber 301, lens 302 and first window 303 and Second Window 306.Make outgoing beam do raster scanning by driving panel control MEMS scanheads, thereby the transversal scanning scope that can obtain to pop one's head in, comprise OCT areas imaging (X-direction) 304 and with the Y-direction areas imaging of depth direction, in conjunction with the OCT imaging system, to obtain the optical fault image of the transversal scanning scope that X-direction and Y-direction together form, can obtain the 3-dimensional image of oral cavity tissue sample.The visual imaging scope 307 of imageing sensor 308 will comprise the transversal scanning scope of probe, thereby visual pattern that can be by 308 crawls of this imageing sensor positions the position of OCT 3-dimensional image.
According to the difference of MEMS scanning probe direction, inner each image-forming block of the inserting end of described scanned imagery device can have 4 kinds of different structural configuration.(the referenced patent: 201210039188.1 1 kinds of optic probes that improve optical quality) adopt side direction scanning work mode of MEMS scanheads among Fig. 3, MEMS scanheads (referenced patent: 201210363551.5 among Fig. 4, a kind of MEMS optic probe) adopts the scan forward working method, the MEMS scanheads adopts side scan forward working method among Fig. 5, (the referenced patent: a kind of optical scanner based on the MEMS micro mirror) adopt ring circumferential scanning working method of MEMS scanheads among Fig. 6.
Among Fig. 4, comprise optical fiber 401, lens 402, MEMS micro mirror 403, first window 404, OCT areas imaging (X-direction) 405, visual imaging scope 406, Second Window 407, imageing sensor 408, rhizoma sparganic reflecting mirror 409;
Wherein, rhizoma sparganic reflecting mirror 409 plays a part to change light path, makes light beam directive MEMS micro mirror minute surface, makes outgoing beam do raster scanning by driving control MEMS micro mirror, thereby obtains the transversal scanning scope of X-direction and Y-direction.Catch the true visual pattern of sample by imageing sensor 408 simultaneously, and from visual pattern, the OCT areas imaging is positioned.
Among Fig. 5, comprise optical fiber 501, lens 502, MEMS micro mirror 504, OCT areas imaging (X-direction) 505, visual imaging scope 506, imageing sensor 507 and reflecting mirror 503, reflecting mirror 503 works to change light path, make light beam do raster scanning by driving control MEMS micro mirror 504, thereby obtain the transversal scanning scope of X-direction and Y-direction.Catch the true visual pattern of sample by imageing sensor 507 simultaneously, and from visual pattern, the OCT areas imaging is positioned.
Among Fig. 6, comprise that optical fiber 601, lens 602, open column shape reflecting mirror 603, MEMS micro mirror 604, imageing sensor 605, sample tissue inwall 606 and OCT encircle circumferential imaging point 507,
Wherein, open column shape reflecting mirror 603 front taper surfaces work to change the probe light path, and MEMS micro mirror minute surface vertically arranges.When the inserting end of described scanned imagery device is the ring circumferential scanning, make outgoing beam do circular scanning, oval scanning, track type scanning or are scan by driving control MEMS micro mirror 604 actuating arms, and can obtain optical ring faultage image shown in Figure 7 in conjunction with the OCT imaging system.
As shown in Figure 8, the MEMS micro mirror of MEMS probe of the present invention employing can adopt electrothermal drive or static driving or Electromagnetic Drive or Piezoelectric Driving.Wherein, described MEMS micro mirror is made of minute surface 800, frame and four actuating arms 801 that are coated with optical coating, actuating arm 801 uniform being arranged at around minute surface 800 and the frame, be provided with the pad 802 that connects for conduction in described frame lower end, described actuating arm 801 adopts multilayer material to form, apply voltage to described actuating arm 801 heating or heat releases, its material ceaselessly produces and expands or contraction, does yaw motion thereby drive minute surface 800.
Fig. 9 as can be known, scanned imagery device 900 is arranged to multiple degrees of freedom bridge method of clamping carries out work, be convenient to doctor's operation, particularly can be integrated with the chaise longue operating board at dental clinic, the doctor can move imaging scanner as required at any time, and its operating distance and angle regulated, be convenient to the scanning to each position soft or hard tissue of oral cavity, will obtain simultaneously stable sample tissue image.
Among Figure 10 shown in the (a) and (b), scanned imagery device 1000 is set to hand-held occupation mode, inserting end adopts different warp architectures to satisfy oral cavity different tissues scanning imagery, be convenient to stretch into simultaneously and catch the true visual pattern of sample by imageing sensor, and from visual pattern, the OCT areas imaging is positioned.For the signal of telecommunication of imageing sensor and MEMS scanheads, can adopt wireless radio frequency mode to carry out the signal transmission.Thereby only need an optical fiber to carry out optic path between system and the scanned imagery device, can play the purpose of simplied system structure, be convenient to assembling.
A kind of optical image checkout gear and formation method for the oral cavity of the present invention, described method comprises the steps:
1) sends to described data acquisition and processing module through opto-electronic conversion behind the real image of image sensor senses sample, the signal of telecommunication after described data acquisition and processing module will be processed is sent to CPU and carries out image processing and recovery, and the video image that forms at last is presented on the display unit;
2) light source is sent to data acquisition and processing module with triggering signal, simultaneously light signal is sent to blender, is sent to respectively reference arm and sample arm after the blender light-splitting processing, i.e. the MEMS scanheads;
3) light beam irradiates that penetrates from the MEMS scanheads is on sample, and the light that the light that sample is returned along the diffuse scattering of the certain thickness the exterior and the interior layer of depth direction and reference arm reflect interferes in blender;
4) interference light is transformed into interference signal through detector, interference signal is input to data acquisition and processing module and CPU after the detector difference processing, by the interference signal after the difference processing is carried out Fourier transformation, obtain sample along the certain thickness tomographic map of depth direction;
5) by the MEMS micro mirror that drives in the panel control OCT imaging probe one dimension or two-dimensional scan are carried out in the target area in the video image region, and at each scanning element repeating step 3)-4), obtain the two and three dimensions tomographic map of target area tissue, itself and video image show by display unit in the lump.
The OCT image of apparatus of the present invention has micron order resolution, may detect the ability of minute lesion under the human body viscera top layer, thereby realizes the early lesion diagnosis, especially the first killer of the mankind--on the early diagnosis of cancer, have bright prospects.The present invention has harmless noinvasive and real-time characteristics, section need not to take a sample, just can be the accurately errorless pathological tissues that finds, diagnosis and operation can be carried out simultaneously, help the doctor to implement the super work of more accurately operation, removal lesion tissue accurately can alleviate recovery time after patient's misery and the desmopyknosis in addition greatly.
The above only is preferred embodiment of the present invention, and is in order to limit the present invention, within the spirit and principles in the present invention not all, any modification of doing, is equal to replacement, improvement etc., all should be included within protection scope of the present invention.
Claims (11)
1. an optical image checkout gear that is used for the oral cavity is characterized in that, comprises the scanned imagery device that is integrated with OCT scanning imaging system and Vision imaging system; Described scanned imagery device is used for obtaining in real time the real video image of oral cavity tissue and two dimension, the three-dimensional optical faultage image of target area.
2. a kind of optical image checkout gear for the oral cavity as claimed in claim 1 is characterized in that, described scanned imagery device comprises handle, the inserting end with optic electric interface and is located at MEMS scanheads and imageing sensor in the described inserting end; The outfan of described MEMS scanheads be connected the outfan of imageing sensor and be connected with described optic electric interface respectively; The areas imaging of described imageing sensor comprises the transversal scanning scope of MEMS scanheads.
3. a kind of optical image checkout gear for the oral cavity as claimed in claim 1, it is characterized in that, described OCT scanning imaging system comprises light source, optical fiber, blender, reference arm, detector, data acquisition and processing module, drives panel, CPU, display unit and is located at the interior MEMS scanheads of described scanned imagery device; Described light source is sent to data acquisition and processing module with triggering signal, simultaneously light signal is delivered to blender by optical fiber transmission, and the hybrid light source that obtains after the blender light-splitting processing is sent to respectively reference arm and MEMS scanheads; The interference signal that the two-way light that another outfan of described blender will form through the light that the sample diffuse scattering is returned produces is input to detector, and after this detector difference processing, be input to described data acquisition and processing module, the signal of telecommunication after described data acquisition and processing module will be processed is delivered to CPU and is carried out image processing and recovery, and the OCT image that forms at last is presented on the display unit; Wherein, described driving panel input is connected with described CPU, and its outfan connects respectively the MEMS micro mirror drive end of described data acquisition and processing module and MEMS scanheads; Described Vision imaging system comprises the imageing sensor of being located in the described scanned imagery device, the real time imaging of described image sensor senses sample also sends to described data acquisition and processing module by opto-electronic conversion, the signal of telecommunication after described data acquisition and processing module will be processed is sent to CPU and carries out image processing and recovery, and the vision imaging that forms at last is presented on the display unit.
4. a kind of optical image checkout gear for the oral cavity as claimed in claim 1 is characterized in that, the inserting end of described scanned imagery device can be realized side direction scanning or scan forward or side scan forward or ring circumferential scanning.
5. a kind of optical image checkout gear for the oral cavity as claimed in claim 2 is characterized in that, the driving signal of described MEMS scanheads and described imageing sensor carry out signal transmission control by wired or wireless RF-wise and system.
6. a kind of optical image checkout gear for the oral cavity as claimed in claim 4, it is characterized in that, when the inserting end of described scanned imagery device is the ring circumferential scanning, make outgoing beam do circular scanning or oval scanning or track type scanning or are scan by driving panel control MEMS micro mirror actuating arm, and obtain the optical ring faultage image in conjunction with the OCT imaging system.
7. a kind of optical image checkout gear for the oral cavity as claimed in claim 2 is characterized in that, described scanned imagery device is arranged to hand-held or is arranged to multiple degrees of freedom bridge method of clamping and carries out work.
8. such as each described a kind of optical image checkout gear for the oral cavity of claim 1-7, it is characterized in that, the inserting end of described scanned imagery device adopts the warp architecture of being convenient to oral cavity different tissues scanning imagery.
9. a kind of optical image checkout gear for the oral cavity as claimed in claim 3 is characterized in that, described MEMS micro mirror adopts electrothermal drive or static driving or Electromagnetic Drive or Piezoelectric Driving.
10. a kind of optical image checkout gear for the oral cavity as claimed in claim 9, it is characterized in that, described MEMS micro mirror is made of minute surface, frame and four actuating arms that are coated with optical coating, actuating arm is uniform to be arranged at around minute surface and the frame, be provided with the pad that connects for conduction in described frame lower end, described actuating arm adopts multilayer material to form, and applies voltage to described actuating arm heating or heat release, its material production expands or shrinks, and does yaw motion thereby drive minute surface.
11. such as claim 1 to 10 each described a kind of optical image checkout gear and formation method for the oral cavity, it is characterized in that, described method comprises the steps:
1) sends to described data acquisition and processing module through opto-electronic conversion behind the real image of image sensor senses sample, the signal of telecommunication after described data acquisition and processing module will be processed is sent to CPU and carries out image processing and recovery, and the video image that forms at last is presented on the display unit;
2) light source is sent to blender with light signal, is sent to respectively reference arm and sample arm after the blender light-splitting processing, i.e. the MEMS scanheads;
3) light beam irradiates that penetrates from the MEMS scanheads is on sample, and the light that the light that sample is returned along the diffuse scattering of the certain thickness the exterior and the interior layer of depth direction and reference arm reflect interferes in blender;
4) interference light is transformed into the signal of telecommunication through detector, again the described signal of telecommunication is input to data acquisition and processing module and CPU, carry out series of signals by the described signal of telecommunication and process, comprising Fourier transformation, obtain sample along the tomographic map in the depth direction certain thickness;
5) by the MEMS micro mirror that drives in the panel control OCT imaging probe one dimension or two-dimensional scan are carried out in the target area in the video image region, and at each scanning element repeating step 3)-4), obtain the two and three dimensions tomographic map of target area tissue, itself and video image show by display unit in the lump.
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| CN106606353A (en) * | 2017-03-03 | 2017-05-03 | 中国人民武装警察部队总医院 | Tooth self-examination system and self-examination method thereof |
| CN106709967A (en) * | 2016-12-23 | 2017-05-24 | 天津恒宇医疗科技有限公司 | Endoscopic imaging algorithm and control system |
| CN107854116A (en) * | 2017-11-15 | 2018-03-30 | 上海交通大学 | A kind of oral soft tissue metabolism monitoring system and method |
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| CN109124588A (en) * | 2018-09-25 | 2019-01-04 | 南开大学 | A kind of OCT probe for mouth disease inspection |
| CN109788885A (en) * | 2016-07-20 | 2019-05-21 | 登塔尔图像科技公司 | Optical coherence tomography system |
| CN111053531A (en) * | 2019-11-20 | 2020-04-24 | 南京理工大学 | Handheld oral angiography device and method based on sweep frequency optical coherence tomography |
| CN111956174A (en) * | 2020-09-01 | 2020-11-20 | 河南医学高等专科学校 | Oral cavity examination device for department of stomatology |
| CN113080850A (en) * | 2021-03-25 | 2021-07-09 | 苏州阿格斯医疗技术有限公司 | Method for measuring scanning range of optical interference tomography system |
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