CN106680476B - A kind of immuno-chromatography detection device for secretion sample - Google Patents
A kind of immuno-chromatography detection device for secretion sample Download PDFInfo
- Publication number
- CN106680476B CN106680476B CN201710053566.4A CN201710053566A CN106680476B CN 106680476 B CN106680476 B CN 106680476B CN 201710053566 A CN201710053566 A CN 201710053566A CN 106680476 B CN106680476 B CN 106680476B
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- China
- Prior art keywords
- sample
- mixing vessel
- detection components
- groove
- chromatography
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Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/5302—Apparatus specially adapted for immunological test procedures
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/5302—Apparatus specially adapted for immunological test procedures
- G01N33/5304—Reaction vessels, e.g. agglutination plates
Abstract
The invention discloses a kind of immuno-chromatography detection devices of secretion sample, including a sample mixing vessel, a detection components and a movable stand.The present invention realizes the processing of sample in a unified device, the control of sample-adding, and since operation is carried out in the system of a relative closure, also reduce the possibility of sample contamination to a certain extent, the simplicity of operation decreases the hidden danger of manual operation error.
Description
Technical field
The invention belongs to medicinal detection device technical fields, and in particular to a kind of immunochromatography for secretion sample is examined
Survey device.
Background technology
Chromatography detection device is due to needing other many instruments to be used cooperatively at present, and there is certain not convenient on
Property.And to urine, either the detection of excreta equal samples needs that the sample of acquisition is diluted or is mixed in many cases
It is loaded again after processing.Currently, the processing to sample generally carries out in independent container, use again later pipettor to sample into
Row transfer sample-adding.Operation mode so there is a possibility that sample contamination, and be related to more vessel, for certain
The sample of sensibility, the also processing scheme of non-optimal.
Invention content
It is an object of the invention to overcome prior art defect, a kind of immunochromatography detection for secretion sample is provided
Device.
Technical scheme is as follows：
A kind of immuno-chromatography detection device for secretion sample, including：
One sample mixing vessel is located at the through-hole of sample mixing vessel bottom wall with a sample collection port and one；
One detection components have chimeric each other a lower housing and a upper shell, and a chromatography strip is equipped in the lower housing,
There is the upper shell sample-adding portion of a sample application zone for corresponding to chromatography strip, one to correspond to the observation window for the results display area for chromatographing strip
The label window of the hand handle label of strip is chromatographed with a correspondence, the groove for being adapted to sample mixing vessel with one in the sample-adding portion should
The well of the sample application zone of strip is chromatographed in groove with a connection；
With a movable stand, there is parallel and the setting that is fixedly connected a lower plate and a upper plate, the spacing of the upper plate and lower plate
Upper end to the upper surface of detection components of sample mixing vessel when less than or equal to the groove for being set to sample-adding portion when sample mixing vessel
Distance, the lower plate have at least one sliding be adapted to detection components sliding opening；
Sample mixing vessel is slidably arranged in along the length direction of chromatography strip in the groove in sample-adding portion of detection components, and
Opposite detection components have a communicating position and a detent position, and when in load position, sample mixing vessel bottom wall leads to
Hole by well with chromatography strip sample application zone be connected to, when in the closed position, the through-hole of sample mixing vessel bottom wall and
Well is staggered and is closed by the sample-adding portion of upper shell；Inspection in sliding opening of the upper plate of movable stand lower plate will be adapted to
The sample mixing vessel surveyed on component is pushed into load position by detent position.
In a preferred embodiment of the invention, the sample mixing vessel and detection components are equipped with a position restrainer
Structure so that when in the closed position, sample mixing vessel is relatively fixed with detection components.
It is further preferred that the position-limit mechanism include at least one be set to sample mixing vessel bottom wall limit protrusion and
At least one is set to the limit pits for being adapted to the limit protrusion in the groove in sample-adding portion.
In a preferred embodiment of the invention, an at least guide groove, institute are equipped in the groove in the sample-adding portion
The bottom wall for stating sample mixing vessel is oriented to draw runner at least one be adapted to the sliding of an above-mentioned at least guide groove is had.
It is further preferred that the lower end for being oriented to draw runner is equipped with and is clamped the grab being adapted to guide groove.
In a preferred embodiment of the invention, the sample mixing vessel is made of transparent material, has thereon
Liquid level line.
Beneficial effects of the present invention：
1, the present invention realizes the processing of sample, the control of sample-adding in a unified device, and is due to operating
It is carried out in the system of a relative closure, also reduces the possibility of sample contamination, the simplicity of operation to a certain extent
Reduce the hidden danger of manual operation error.
2, reaction starting, improves detection efficiency while movable stand of the invention can realize multiple detection samples.
Description of the drawings
Fig. 1 is the dimensional structure diagram of the present invention.
Fig. 2 is the perspective exploded view of the present invention.
Fig. 3 is the dimensional structure diagram of the detection components of the present invention.
The sectional view of the sample mixing vessel of the positions Fig. 4 present invention and detection components cooperation.
Fig. 5 is one of the usage state diagram of the present invention.
Fig. 6 is the two of the usage state diagram of the present invention.
Specific implementation mode
Technical scheme of the present invention is further detailed and is described below by way of specific implementation mode combination attached drawing.
Embodiment 1
As depicted in figs. 1 and 2, a kind of immuno-chromatography detection device for secretion sample, including sample mixing are held
Device 1, a detection components 2 and a movable stand 3.
As shown in Fig. 1,2 and 4, there is sample mixing vessel 1 a sample collection port 11 and one to be located at sample mixing vessel 1
The through-hole 12 of bottom wall, it is preferred that be made of transparent material, there is liquid level line thereon；
As shown in Figures 2 to 4, detection components 2 have chimeric each other a lower housing 21 and a upper shell 22, the lower casing
A chromatography strip 210 is equipped in body 21, which has a sample-adding portion 221, one for corresponding to the sample application zone for chromatographing strip 210
The observation window 222 and one of the results display area of corresponding chromatography strip 210 corresponds to the label window of the hand handle label of chromatography strip 210
223, the Control lines and Test lines that chromatograph strip 210 can be observed by observation window 222, have one to fit in the sample-adding portion 221
Groove 2210 with sample mixing vessel 1, the well of the interior sample application zone that strip 210 is chromatographed with a connection of the groove 2210
2211；An at least guide groove 2212, the bottom wall of the sample mixing vessel 1 are equipped in the groove 2210 in the sample-adding portion 221
To having at least one guiding draw runner 13 be adapted to the sliding of an above-mentioned at least guide groove 2212, under the guiding draw runner 13
End is equipped with is clamped the grab 130 being adapted to guide groove 2212.；
As depicted in figs. 1 and 2, movable stand 3 have parallel and the setting that is fixedly connected a lower plate 31 and a upper plate 32, should
Upper plate 32 is mixed with sample when being smaller than equal to the groove 2210 for being set to sample-adding portion 221 when sample mixing vessel 1 of lower plate 31
There is at least one sliding to be adapted to detection components 2 for the distance of the upper end of container 1 to the upper surface of detection components 2, the lower plate 31
Sliding opening 310；
As shown in Figure 3 and Figure 4, sample mixing vessel 1 is slidably arranged in detection components along the length direction of chromatography strip 210
In the groove 2210 in 2 sample-adding portion 221, and opposite detection components 2 have a communicating position and a detent position, when in sample-adding
When position, the through-hole 12 of 1 bottom wall of sample mixing vessel is connected to by well 2211 with the sample application zone of chromatography strip 210, and place is worked as
When detent position, through-hole 12 and the well 2211 of 1 bottom wall of sample mixing vessel are staggered and by the sample-adding portion 221 of upper shell 22
Closing；The sample mixing in detection components 2 in sliding opening 310 of the upper plate 32 of movable stand 3 lower plate 31 will be adapted to
Container 1 is pushed into load position by detent position；Sample mixing vessel 1 and detection components 2 are equipped with a position-limit mechanism so that when in
When detent position, sample mixing vessel 1 is relatively fixed with detection components 2, it is preferred that the position-limit mechanism is set to including at least one
The limit protrusion 14 of the bottom wall of sample mixing vessel 1 and at least one is set to the adaptation limit in the groove 2210 in sample-adding portion 221
The limit pits 2213 of protrusion 14.
The specifically used method of the present invention is as follows：
(1) as shown in figure 5, when sampling, sample is collected by conduit cotton swab 4, is then placed in sample mixing vessel 1, is used
Auxiliary liquid (being placed in auxiliary liquid container 5) rinses or impregnates conduit cotton swab 4, and sample thereon is made to rush in into sample mixing appearance
In device 1, sample mixing vessel 1 is in detent position with respect to detection components 2 at this time.
(2) as shown in fig. 6, waiting for that the liquid handling in sample mixing vessel 1 finishes, detection group is placed in the promotion of movable stand 3
Sample mixing vessel 1 in the groove 2210 of part 2, sample mixing vessel 1 are moved to load position, sample along guide groove 2212
Liquid in mixing vessel 1 is contacted by through-hole 12 and well 2211 with the sample application zone of chromatography strip 210, is realized sample-adding, is waited for
222 testing result of observation window can be passed through after a period of time.
The foregoing is only a preferred embodiment of the present invention, therefore cannot limit the scope of implementation of the present invention according to this, i.e.,
According to equivalent changes and modifications made by the scope of the claims of the present invention and description, all should still belong in the range of the present invention covers.
Claims (4)
1. a kind of immuno-chromatography detection device for secretion sample, it is characterised in that：Including：
One sample mixing vessel is located at the through-hole of sample mixing vessel bottom wall with a sample collection port and one；
One detection components have chimeric each other a lower housing and a upper shell, and a chromatography strip is equipped in the lower housing, on this
There is shell the sample-adding portion of a sample application zone for corresponding to chromatography strip, one to correspond to the observation window and one for the results display area for chromatographing strip
Correspond to the label window of the hand handle label of chromatography strip, the groove for being adapted to sample mixing vessel with one in the sample-adding portion, the groove
Inside there is the well of the sample application zone of connection chromatography strip；
With a movable stand, there is parallel and the setting that is fixedly connected a lower plate and a upper plate, the upper plate and lower plate to be smaller than
Equal to when sample mixing vessel be set to sample-adding portion groove when sample mixing vessel upper end to the upper surface of detection components away from
From the lower plate has the sliding opening that at least one sliding is adapted to detection components；
Sample mixing vessel is slidably arranged in along the length direction of chromatography strip in the groove in sample-adding portion of detection components, and opposite
Detection components have a communicating position and a detent position, and when in load position, the through-hole of sample mixing vessel bottom wall is logical
It crosses well and is connected to the sample application zone for chromatographing strip, when in the closed position, the through-hole and sample-adding of sample mixing vessel bottom wall
Hole is staggered and is closed by the sample-adding portion of upper shell, and sample mixing vessel and detection components are equipped with a position-limit mechanism so that when in
When detent position, sample mixing vessel is relatively fixed with detection components；The upper plate of movable stand will be will adapt to the sliding of lower plate
Sample mixing vessel in detection components in opening is pushed into load position by detent position；It is equipped in the groove in above-mentioned sample-adding portion
An at least guide groove, the bottom wall of the sample mixing vessel to have be adapted to the sliding of an above-mentioned at least guide groove to
Few one is oriented to draw runner.
2. a kind of immuno-chromatography detection device for secretion sample as described in claim 1, it is characterised in that：The limit
Position mechanism includes that the limit protrusion of at least one bottom wall for being set to sample mixing vessel and at least one are set in the groove in sample-adding portion
It is adapted to the limit pits of the limit protrusion.
3. a kind of immuno-chromatography detection device for secretion sample as described in claim 1, it is characterised in that：It is described to lead
It is equipped with to the lower end of draw runner and is clamped the grab being adapted to guide groove.
4. a kind of immuno-chromatography detection device for secretion sample as described in claim 1, it is characterised in that：The sample
This mixing vessel is made of transparent material, has liquid level line thereon.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710053566.4A CN106680476B (en) | 2017-01-22 | 2017-01-22 | A kind of immuno-chromatography detection device for secretion sample |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710053566.4A CN106680476B (en) | 2017-01-22 | 2017-01-22 | A kind of immuno-chromatography detection device for secretion sample |
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| Publication Number | Publication Date |
|---|---|
| CN106680476A CN106680476A (en) | 2017-05-17 |
| CN106680476B true CN106680476B (en) | 2018-08-03 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710053566.4A Active CN106680476B (en) | 2017-01-22 | 2017-01-22 | A kind of immuno-chromatography detection device for secretion sample |
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| CN (1) | CN106680476B (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107064484A (en) * | 2017-05-25 | 2017-08-18 | 杭州博旭生物技术有限公司 | Self-priming Dry-type biochemical detection means |
| CN112871029B (en) * | 2019-11-29 | 2022-06-14 | 深圳市帝迈生物技术有限公司 | Sample adding and mixing method, sample adding and mixing device, computer storage medium, sample analysis method and sample analysis device |
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| CN1882836A (en) * | 2003-11-14 | 2006-12-20 | 香港澳维有限公司 | Rapid sample analysis and storage devices and methods of use |
| CN101283274A (en) * | 2005-08-05 | 2008-10-08 | 因弗因斯医药瑞士股份有限公司 | Assay reading device with display |
| CN201780300U (en) * | 2010-08-17 | 2011-03-30 | 日照新隆特生物科技有限公司 | Medical test strip box |
| CN103267839A (en) * | 2013-04-28 | 2013-08-28 | 上海快灵生物科技有限公司 | Enclosed chromatographic test strip plastic card box |
| CN104042253A (en) * | 2013-03-15 | 2014-09-17 | 奥索临床诊断有限公司 | Rotatable disk-shaped fluid sample collection device |
| CN206710436U (en) * | 2017-01-22 | 2017-12-05 | 英科新创(厦门)科技有限公司 | Immuno-chromatography detection device for secretion sample |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003044534A1 (en) * | 2001-11-22 | 2003-05-30 | Wakunaga Pharmaceutical Co.,Ltd. | Immunochromatographic test strip for measuring analysis subject in specimen in trace amount |
| JP4213553B2 (en) * | 2003-10-10 | 2009-01-21 | 浜松ホトニクス株式会社 | Immunochromatographic test strip reader |
| KR100506165B1 (en) * | 2005-02-02 | 2005-08-05 | 주식회사 에스디 | Non-continuous immunoassay device and immunoassay method using the same |
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Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1882836A (en) * | 2003-11-14 | 2006-12-20 | 香港澳维有限公司 | Rapid sample analysis and storage devices and methods of use |
| CN101283274A (en) * | 2005-08-05 | 2008-10-08 | 因弗因斯医药瑞士股份有限公司 | Assay reading device with display |
| CN201780300U (en) * | 2010-08-17 | 2011-03-30 | 日照新隆特生物科技有限公司 | Medical test strip box |
| CN104042253A (en) * | 2013-03-15 | 2014-09-17 | 奥索临床诊断有限公司 | Rotatable disk-shaped fluid sample collection device |
| CN103267839A (en) * | 2013-04-28 | 2013-08-28 | 上海快灵生物科技有限公司 | Enclosed chromatographic test strip plastic card box |
| CN206710436U (en) * | 2017-01-22 | 2017-12-05 | 英科新创(厦门)科技有限公司 | Immuno-chromatography detection device for secretion sample |
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| CN106680476A (en) | 2017-05-17 |
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Address after: 361000 Xinguang Road 332, Haicang Xinyang Industrial Zone, Xiamen City, Fujian Province Patentee after: Yingke Xinchuang (Xiamen) Science and Technology Co., Ltd. Address before: 361000 Xinguang Road 332, Haicang Xinyang Industrial Zone, Xiamen City, Fujian Province Patentee before: Yingke Xinchuang (Xiamen) Science & Technology Co., Ltd. |