CN101283274A - Assay reading device with display - Google Patents

Assay reading device with display Download PDF

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Publication number
CN101283274A
CN101283274A CNA2006800370549A CN200680037054A CN101283274A CN 101283274 A CN101283274 A CN 101283274A CN A2006800370549 A CNA2006800370549 A CN A2006800370549A CN 200680037054 A CN200680037054 A CN 200680037054A CN 101283274 A CN101283274 A CN 101283274A
Authority
CN
China
Prior art keywords
equipment
display
measurement result
carrier
liquid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CNA2006800370549A
Other languages
Chinese (zh)
Inventor
戴维·斯马特
安德鲁·彼得·费伦
罗伯特·安德鲁·波特
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ENFOVYNSI MEDICAL SWITZERLAND Co Ltd
Alere Switzerland GmbH
Original Assignee
ENFOVYNSI MEDICAL SWITZERLAND Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ENFOVYNSI MEDICAL SWITZERLAND Co Ltd filed Critical ENFOVYNSI MEDICAL SWITZERLAND Co Ltd
Publication of CN101283274A publication Critical patent/CN101283274A/en
Pending legal-status Critical Current

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Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5023Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures with a sample being transported to, and subsequently stored in an absorbent for analysis
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/84Systems specially adapted for particular applications
    • G01N21/8483Investigating reagent band
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366Apparatus specially adapted for solid-phase testing
    • G01N33/54386Analytical elements
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/02Identification, exchange or storage of information
    • B01L2300/025Displaying results or values with integrated means
    • B01L2300/027Digital display, e.g. LCD, LED
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0809Geometry, shape and general structure rectangular shaped
    • B01L2300/0825Test strips

Abstract

Disclosed is an assay result reading apparatus for reading the result of an assay performed by contacting a liquid sample with a liquid carrier or transport on or in which the assay is performed, the assay result reading apparatus comprising: a receptacle to receive the liquid carrier or transport; a reader to read the result of the assay; and a releasable attachment for releasably attaching a display which can display the assay result.

Description

Mensuration fetch equipment with display
Technical field
The present invention relates to a kind of sensing equipment and reader of one, wherein this sensing equipment is provided with the device that adheres to display releasedly.
Background technology
The simple sensing equipment that is used for keeping healthy and is used to check the family of analyte to check is produced widely and can be obtained by commercial sources now.
EP291194 has disclosed a kind of sensing equipment that comprises the porous carrier that contains particle mark binding reagents, and this particle mark binding reagents can move freely in solution and be exclusively used in conjunction with the analyte of being paid close attention to.This equipment also comprises the unmarked special combination reagent that is used for identical analyte, and wherein, unmarked binding reagents is fixed in the check district that is arranged in special combination reagent downstream.Being contained the liquor sample of paying close attention to analyte to some extent is applied to porous carrier and reacts to form mark analyte-binding partner compound with labelled reagent.During this compound was moved to check district along porous carrier, it interacted with the unmarked special combination reagent that is fixed and forms compound herein, therefore made it possible to determine the amount of the analyte that exists in sample.Yet such mensuration requires by the user result to be made explanations, and this explanation may be inaccurate.
In order to use with the concentration of the analyte in definite liquor sample and/or the electronic reader of amount in conjunction with the mensuration strip is known.Disclosed an example of this reader/test strip combination in EP0653625, wherein reader uses optical means to determine assay.Measure that strip is inserted in the reader and from light source for example the light of light emitting diode (LED) be irradiated on the strip.Then by the light of photodetector detection of reflected or transmission, allow to determine to be attached to fixating reagent thus and the amount of the mark analyte in the check district, assembled.
Importantly, the mensuration reader and the strip of this equipment are carefully aimed at, this is due to the fact that, i.e. the optical signal narrower in width that forms in detection zone (and control zone) and therefore detect or the generation appreciable impact can be read to what photodetector carried out with respect to the little displacement of corresponding light electric explorer in the control zone.Further think, thereby require that photodetector is near as far as possible must to obtain optimum signal intensity near strip.Therefore, importantly, the user aims at the measurement result reader carefully with strip when using this equipment.In particular for the equipment that is intended to be used for house, this accurate aligning may be difficult.
In order to overcome this problem, designed wherein strip and reader and be incorporated into sensing equipment in the single integrated unit.An example that is applicable to the sensing equipment that detects human chorionic gonadotrophin (hCG) by Unipath company limited with brand name Clearblue Digital TMSell.This equipment comprises measures the display that assay is measured in strip, reader and demonstration.
This integrated electronic sensing equipment has the following advantages, and they have improved the accuracy of measurement result, need not by the user result to be made an explanation.This equipment in the present technique field be known and, for example, in EP1484601, EP1484611 and EP1484613, disclosed.Usually, integrated unit is provided with device, chromacoder, display device, circuit and the power supply that is used to read measurement result.Traditionally, display comprises needs power supply to change and to keep the LCD of display message.Be with a this device-dependent shortcoming, in case power source exhausts or is removed, the information dropout of Xian Shiing then.Therefore, this sensing equipment requires constant power supply to show measurement result.Thus, shown result's life-span is determined by used power source.
Summary of the invention
In first aspect, the invention provides a kind of measurement result fetch equipment, be used to read by with liquor sample contact liq carrier or carry the result of the mensuration that body carries out, described be determined at described liquid-carrier or carry on the body or among carry out, this measurement result fetch equipment comprises: be used for the receiver that receives liquid-carrier or carry body; Be used for reading the reader of measurement result; With the discharged attachment device that is used for adhering to releasedly the display that can show measurement result.
Preferably this equipment also comprises the display that adheres to releasedly, and this display is preferably The zenithal bistable device, and this term will be explained below.
Attachment device can be discharged and any suitable mechanism that is used for releasedly display being attached to this equipment can be comprised.Preferably, this mechanism be can be any instrument a kind of (for example, avoid turnscrew etc. requirement) that activate.In one embodiment, provide the part of elastically deformable on shell or display, this part can suitably be held and be remained in corresponding hole, recess or the groove on display or the shell.
Liquid-carrier or conveying body preferably include lateral flow assay device or strip.This lateral flow assay device or strip are familiar with by those skilled in the art of the present technique.Usually, they comprise porous matrix, and for example nitrocellulose or materials similar are usually with support or supporting layer.This support or supporting layer can comprise the material of relative stiffness, for example synthetic plastics material.Mylar is especially suitable in this respect.
In one embodiment, this liquid-carrier or conveying body comprise the integrated component of this equipment, thereby the invention provides a kind of integrated equipment that exist and/or measure of mensuration with detecting liquid analyte that sample is paid close attention to that be used for carrying out.In other embodiments, liquid-carrier or conveying body do not form the integrated component of present device.For example, can make and sell suitable lateral flow test strip individually.In a specific embodiment, equipment of the present invention comprises in order to form with liquid-carrier or conveying body can discharge the device that engages.Preferably, thus liquid-carrier or carry body can be inserted in the measurement result reading device of the present invention and read measurement result, and in case finished and read, liquid-carrier or carry body to be ejected or to remove and to go out of use then from fetch equipment.
According to the present invention, after producing measurement result, display can be pulled down from this equipment, and when not having power source actually, the information that writes down on display can be kept one section finite time at least.Preferably, when not having power source, this demonstration can be held at least 24 hours, and more preferably at least 72 hours, and most preferably at least 168 hours.
For current purpose, the display that maintenance information in this case shows can be called as The zenithal bistable device.Preferred The zenithal bistable device is an electrical equipment, means, originally power supply is used to the demonstration of generation information or changes this demonstration, but after this, need not any power source and be used for the demonstration of maintenance information.Ideally, information display comprises aplhanumeric visual display.Preferred The zenithal bistable device can be from ZBD (zenithal bistable display; Malvern ResearchPark, Worcester: see www.zbddisplays.com) obtain.The zenithal bistable display is a kind of like this LCD, and it need not any power source and is used to keep image.This technology is based on the lattice structure (grating structure) by the ZBD development as describing in EP0856164.In the ZBD display, there are two kinds of stable orientations in molecule, thus formation or black or white image.The zenithal bistable display uses the arrangement of a kind of simple micromechanism grid surface with the control liquid crystal molecule.Although still kept thereby the physical shock image takes place after the surface memory image is removing power source this lattice structure.The bistability of display means that complex image can once be written into delegation and need not to use in each pixel back the extra cost of thin film transistor (TFT) (TFTS).
Other The zenithal bistable device that can be used according to the invention is conducting polymer, electrochromic polymeric compounds and electronic ink display.
By electric ink (a plurality of small microcapsule that comprises the particle that contains positive electricity and negative charge) is printed onto on a slice plastic sheeting, this plastic sheeting is laminated on the circuit layer, thereby forms electronic ink display (can obtain from the E Ink company of U.S. CambridgeMA).Can be thereby this circuit forms by display driver control image in case form the pattern of pixels that just can under the situation that does not have power source, be shown.
The BiNem display (can be from Nemoptic, 1 rue Guynemer, Magny lesHameaux, France obtains) use the LCD technology to form display.This display device be bistable (that is, and two kinds heteroid all be stable in any), thereby need not any power source owing to the storage inside effect keeps displaying contents.In addition, this display uses the nematic liquid crystal that most of LCD use.
By Dupont (120 Cremona Driva, Santa Barbara, California, the U.S.) thus the Olight display of development uses organic material luminous.The organic material thin layer is sandwiched between suitable anode and the cathode layer and strides organic material and applies the moderate relatively voltage (usually between 2 to 10V) of size, so that it is luminous to be called electroluminescent process.By after power source removes, this demonstration can be held one section finite time.
Any in the aforementioned display applicable among the present invention.
According to the present invention, The zenithal bistable device can be used to show the relevant information of measuring.Usually, display is used to indicate measurement result.Alternately, perhaps additionally, display can be used to show date and time, patient information, batch code information of mensuration etc.Can use any suitable separation well known by persons skilled in the art or releasing mechanism with display from integrated device separates.In one embodiment, but can use releasable that display is attached to this equipment.Be easily, can with The zenithal bistable device from integrated equipment remove and maintenance and saving result to be for future reference.
Typically, present device also is provided with conversion of signals mechanism, circuit and power source.
Evaluation method selecting optimal equipment of the present invention ground comprises lateral flow immunoassay device, wherein may contain the liquor sample of paying close attention to analyte to some extent and be applied to strip and move along strip.Such mensuration is well known to those skilled in the art and for example discloses in EP0291194.
In a preferred embodiment of the invention, strip and the sample reception area liquid flow communication that applies sample to it.This strip generally includes that contain can be in conjunction with the analyte of being paid close attention to the reaction zone of the special combination reagent that forms reagent-analyte compound with contain the check district of fixating reagent that can binding reagents-analyte compound.
Usually, reaction zone is positioned at the downstream of sample reception area and the downstream that the check district is positioned at reaction zone.
Preferably, strip is a porous, therefore allows sample to permeate along strip.More preferably, nitrocellulose is selected as test strip material.This has and exceeds for example advantage of paper of traditional test strip material, need not the natural performance of sensitization early because it has conjugated protein.
In a preferred embodiment, in the check district reagent-analyte compound is attached to the feasible signal that generates of fixating reagent, this signal use is measured reader and is measured.In principle, integrated equipment of the present invention can be used to detect any amount or the existence of analyte.Sample can be derived from biology, industry or environment.
At the signal that carries out gathering between test period, can be to be applicable to any signal of measuring purpose.Usually, gathering of signal comprises the material that is easy to detect, colored reaction product for example, formation or gather.Preferably, this mensuration is included in gathering of labelled reagent in the check district of strip.The example of some marks that can be used according to the invention has enzyme, radioactive label, fluorescent dye, coloured particle etc.Preferably, this mark comprises marking particle, and wherein this marking particle can be goldc grains or colored polymeric, for example latex.
Usually, the existence of the analyte in sample will be tending towards causing gathering of signal.Yet in other mensuration form (for example mensuration of competitiveness or displacement format), not existing of the analyte of being paid close attention to will make relevant signal gather.
In a preferred embodiment of the invention, the measurement result reader comprises the optical detector system of gathering that is used for eas marker.This reader generally comprises the device that produces with the proportional signal of mark level (digital signal ideally) that is gathered.Be easily, optical detector system can be used to measure any optical property, for example, and from the check district reflection of wherein gathering mark and/or the light quantity of transmission.
Preferably, this optical detection system will comprise at least one light source and at least one photodetector.More preferably, this light source comprises light emitting diode (LED).Be reflected or the light of transmission is measured by photodetector.For current purpose, adopt reflected light to be reflected to light on the photodetector from porous carrier or other liquid transporting apparatus from light source with expression.Usually, in this case, detector is set on the side of the carrier identical with light source.Adopt transmitted light with the light of expression by this carrier.In order to detect projection light, detector is arranged on the side of the carrier relative with light source usually.
Preferably, this equipment comprises the shell that is formed by opaque material.Be easily, this shell is by synthetic plastics material, and for example polycarbonate, ABS, polystyrene or polypropylene form.Ideally, at an end place of shell opening is set, thereby strip or similar porous carrier can insert by this hole, perhaps being contained in then can be outstanding by this hole in this shell.Carry out mensuration measurement, the strip contact liq sample that in this equipment, holds in order to use according to integrated equipment of the present invention.In alternative embodiment, liquor sample can at first be applied to the sample reception area of strip, and then strip is inserted in this equipment.The relevant reaction of any analyte experience that sample moves and exists in sample along strip.
In case the result is determined, then display can be pulled down and be saved to be for future reference from this equipment.Preferably, originally display can be attached to this equipment and be removed after measuring subsequently.
Advantageously, equipment of the present invention can be used in the family or the check aspect that is used for keeping healthy.
In one embodiment, equipment of the present invention can be used to detect human chorionic gonadotrophin.Therefore, for example, the display that positive result (promptly conceived) is shown can remove and keeps as souvenir or souvenir from present device, and shown information will can not lost.
According to another embodiment, equipment of the present invention can be used to detection of infectious pathogens, for example the A streptococcus or be used for diagnosing transmissible or other disease.Advantageously, this equipment can be used to check at home and whether have an A streptococcus.Display then can be from this device separates and the result can be delivered to doctor or other medical professional then.
In a further embodiment, equipment of the present invention can be used to detection of drugs of abuse.
Before the present invention, can not be independent of sensing equipment ground saving result.Therefore, traditional lateral flow assay device often makes display by the sample contamination from sensing equipment.Equipment of the present invention has the following advantages, but promptly the display slave unit separates, and therefore reduces and disseminates or scatter the risk of contaminated material and improve sanitary condition thus.
In second aspect, the invention provides a kind of determine in sample the to pay close attention to existence of analyte and/or the method for amount, this method comprises makes the step of this sample contact according to the liquid-carrier of the equipment of first aspect defined above.
In the third aspect, the invention provides the method for a kind of manufacturing according to the integrated equipment of the invention described above first aspect.
Further, the invention provides a kind of integrated equipment, be used for carrying out mensuration with according to first aspect check defined above in the existing and/or measure of analyte that liquor sample is paid close attention to, wherein this equipment has the device for attachment to The zenithal bistable device.
In order to eliminate doubt, spell out, the of the present invention any feature that is described to " preferably ", " desirable ", " easily ", " favourable " etc. can be adopted individually or be adopted in combination with any other feature or a plurality of feature so described, unless indicate in addition in the literary composition.
Description of drawings
Further describe the present invention by illustrative example and with reference to following accompanying drawing now, among the figure:
Fig. 1 is the skeleton view according to an embodiment of integrated sensing equipment of the present invention and reader and the display that is attached;
Fig. 2 is the skeleton view of equipment shown in Figure 1, and wherein display is attached;
Fig. 3 is the planimetric map of the embodiment of equipment shown in Figure 2; With
Fig. 4 is the side view of partly cutting open (wherein display is attached) of equipment shown in Figure 1.
Embodiment
Example 1
Fig. 1 illustrates the embodiment according to integrated equipment of the present invention.
Roughly long 12cm of this equipment and wide 2cm and be roughly the finger or the shape of cigar shape.Yet, can use any shape easily.This integrated equipment comprises the shell (2) that is formed by opaque synthetic plastics material.End place at this shell is provided with narrow opening, and liquid carries body or carrier (4) to give prominence to above this shell with the contact liq sample by this opening.
The zenithal bistable device (6) is releasably attached to this equipment and to user's display message.After producing measurement result, The zenithal bistable device (6) can remove from this equipment.Make to finish in the downward pressure on the elastic variable clevis (8) and measure and after the result had been shown, The zenithal bistable device can remove from shell.After disconnecting power source, thereby The zenithal bistable device continues to show that the information user of measurement result and any other demonstration can keep this result to be for future reference.Can after slave unit removes or alternately, after exhausting, power source be retained in the information that writes down on the display.
As preferably illustrating in Fig. 3 and 4, shell (2) holds the analytic unit that is identified by reference number (10) substantially.
Two LED aiming at the check district (16) of nitrocellulose lateral flow test strip and the printed circuit board (PCB) (12) of two photodiodes (14) are installed above analytic unit (10) comprises, this check district carries the sampling section (4) of body or carrier to form liquid flow communication with liquid.This check district is the zone gathered when existing (existing as required or not) to pay close attention to analyte of labelled reagent wherein.The optical property of this accumulation affects strip (16), for example its reflectivity or transmittance, this character can be measured by using the LED/ photodiode arrange.Therefore photodiode produces output current, and this size of current is relevant with the amount of the mark that gathers in the check district.
Analytic unit (10) comprises that also power supply (button cell 18) is to power to display (6) when being attached to shell (2).By clip (8) being remained in the hole of being located in the shell (2) with suitable shape and size, display (6) is releasably attached to shell.In addition, groove (20) is located on the cover top portion, slides by the openend from shell (2), and flanged a little part of display (6) can be introduced in this groove.When correctly being located, form at electric connector on the display and electric connector (22) on being located at shell and to contact, guarantee the electrical connection between display (6) and analytic unit (10) thus.
Analytic unit (10) comprises signal conversion part (24), comprises data storing buffer, simulation → digital quantizer (ADC) and microprocessor or microcontroller.Display (6) can respond to the output from microprocessor or microcontroller.

Claims (17)

1. measurement result fetch equipment, be used to read by with liquor sample contact liq carrier or carry the result of the mensuration that body carries out, described be determined at described liquid-carrier or carry on the body or among carry out, described measurement result fetch equipment comprises: the receiver that receives described liquid-carrier or carry body; Read the result's of described mensuration reader; With the discharged attachment device that is used for adhering to releasedly the display that can show described measurement result.
2. equipment according to claim 1 also comprises the display that adheres to releasedly.
3. equipment according to claim 2, wherein, the described display that adheres to releasedly is a The zenithal bistable device.
4. according to each described equipment in the claim of front, also comprise power source.
5. equipment according to claim 4, wherein, described power source is a power supply.
6. according to each described equipment in the claim of front, wherein, described display is when continued to show described measurement result or other information that is shown at least in 24 hours when described equipment is removed.
7. equipment according to claim 6, wherein, described display is when continued to show described measurement result or other information that is shown at least in 72 hours when described equipment is removed.
8. equipment according to claim 6, wherein, described display is when continued to show described measurement result or other information that is shown at least in 168 hours when described equipment is removed.
9. according to each described equipment in the claim of front, wherein, described display comprises bistable liquid crystal display, conducting polymer display, electrochromic polymeric compounds display or electronic ink display.
10. according to each described equipment in the claim of front, also comprise liquid-carrier or carry body.
11. equipment according to claim 10, wherein said liquid-carrier or conveying body are porous.
12. equipment according to claim 10, wherein said liquid-carrier or conveying body comprise lateral flow test strip.
13., also comprise at least one light source and/or at least one photodiode according to each described equipment in the claim of front.
14., also comprise from by one or more parts of selecting the group of forming with lower member: microprocessor or microcontroller according to each described equipment in the claim of front; Simulation → digital quantizer; And data storing buffer.
15. according to each described equipment in the claim of front, wherein, described liquid-carrier or carry body can engage described fetch equipment as a result releasedly is in case and read described measurement result then can be ejected or remove from described equipment.
16. a manufacturing is according to the method for each described measurement result fetch equipment in the claim of front, described method is included in the step of the necessary parts of assembling in the shell, and described shell has the discharged attachment device that is used for adhering to releasedly display.
17. a use is read method for measuring according to each described measurement result fetch equipment among the claim 1-15.
CNA2006800370549A 2005-08-05 2006-08-04 Assay reading device with display Pending CN101283274A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0516099.9 2005-08-05
GB0516099A GB0516099D0 (en) 2005-08-05 2005-08-05 Assay reading device with display

Publications (1)

Publication Number Publication Date
CN101283274A true CN101283274A (en) 2008-10-08

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CNA2006800370549A Pending CN101283274A (en) 2005-08-05 2006-08-04 Assay reading device with display

Country Status (7)

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EP (1) EP1913382A1 (en)
JP (1) JP2009503528A (en)
CN (1) CN101283274A (en)
AU (1) AU2006277747A1 (en)
CA (1) CA2617950A1 (en)
GB (1) GB0516099D0 (en)
WO (1) WO2007017648A1 (en)

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CN103115898A (en) * 2011-11-17 2013-05-22 艾博生物医药(杭州)有限公司 Device for reading test results on test carrier
CN106680476A (en) * 2017-01-22 2017-05-17 英科新创(厦门)科技有限公司 Immune-layer detection device for secretion samples

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Publication number Priority date Publication date Assignee Title
CN103115898A (en) * 2011-11-17 2013-05-22 艾博生物医药(杭州)有限公司 Device for reading test results on test carrier
CN103115898B (en) * 2011-11-17 2018-01-16 艾博生物医药(杭州)有限公司 The reading equipment of result of laboratory test in a kind of test carrier
CN106680476A (en) * 2017-01-22 2017-05-17 英科新创(厦门)科技有限公司 Immune-layer detection device for secretion samples
CN106680476B (en) * 2017-01-22 2018-08-03 英科新创(厦门)科技有限公司 A kind of immuno-chromatography detection device for secretion sample

Also Published As

Publication number Publication date
EP1913382A1 (en) 2008-04-23
WO2007017648A1 (en) 2007-02-15
JP2009503528A (en) 2009-01-29
GB0516099D0 (en) 2005-09-14
CA2617950A1 (en) 2007-02-15
AU2006277747A1 (en) 2007-02-15

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