CN106353261A - Bone alkaline phosphatase analyzer - Google Patents
Bone alkaline phosphatase analyzer Download PDFInfo
- Publication number
- CN106353261A CN106353261A CN201610783533.0A CN201610783533A CN106353261A CN 106353261 A CN106353261 A CN 106353261A CN 201610783533 A CN201610783533 A CN 201610783533A CN 106353261 A CN106353261 A CN 106353261A
- Authority
- CN
- China
- Prior art keywords
- alkaline phosphatase
- detection
- loophole
- base plate
- bone
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 210000000988 bone and bone Anatomy 0.000 title claims abstract description 28
- 102000002260 Alkaline Phosphatase Human genes 0.000 title claims abstract description 25
- 108020004774 Alkaline Phosphatase Proteins 0.000 title claims abstract description 25
- 238000001514 detection method Methods 0.000 claims abstract description 37
- 239000000203 mixture Substances 0.000 claims description 4
- 238000012360 testing method Methods 0.000 abstract description 4
- 238000007689 inspection Methods 0.000 abstract description 2
- 239000002585 base Substances 0.000 description 10
- 238000006243 chemical reaction Methods 0.000 description 8
- 210000004369 blood Anatomy 0.000 description 7
- 239000008280 blood Substances 0.000 description 7
- 238000000034 method Methods 0.000 description 6
- 239000003513 alkali Substances 0.000 description 3
- 239000003153 chemical reaction reagent Substances 0.000 description 3
- 238000004140 cleaning Methods 0.000 description 3
- 230000003287 optical effect Effects 0.000 description 3
- 210000002381 plasma Anatomy 0.000 description 3
- 102000045595 Phosphoprotein Phosphatases Human genes 0.000 description 2
- 108700019535 Phosphoprotein Phosphatases Proteins 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- PXFBZOLANLWPMH-UHFFFAOYSA-N 16-Epiaffinine Natural products C1C(C2=CC=CC=C2N2)=C2C(=O)CC2C(=CC)CN(C)C1C2CO PXFBZOLANLWPMH-UHFFFAOYSA-N 0.000 description 1
- 208000020084 Bone disease Diseases 0.000 description 1
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 1
- 208000002720 Malnutrition Diseases 0.000 description 1
- IOVCWXUNBOPUCH-UHFFFAOYSA-M Nitrite anion Chemical compound [O-]N=O IOVCWXUNBOPUCH-UHFFFAOYSA-M 0.000 description 1
- 102000004160 Phosphoric Monoester Hydrolases Human genes 0.000 description 1
- 108090000608 Phosphoric Monoester Hydrolases Proteins 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000018678 bone mineralization Effects 0.000 description 1
- 229910052791 calcium Inorganic materials 0.000 description 1
- 239000011575 calcium Substances 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 210000004247 hand Anatomy 0.000 description 1
- 238000011065 in-situ storage Methods 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 230000001071 malnutrition Effects 0.000 description 1
- 235000000824 malnutrition Nutrition 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 230000002503 metabolic effect Effects 0.000 description 1
- 229940005654 nitrite ion Drugs 0.000 description 1
- 208000015380 nutritional deficiency disease Diseases 0.000 description 1
- 238000004806 packaging method and process Methods 0.000 description 1
- 230000000149 penetrating effect Effects 0.000 description 1
- 238000005325 percolation Methods 0.000 description 1
- 210000005259 peripheral blood Anatomy 0.000 description 1
- 239000011886 peripheral blood Substances 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 238000003825 pressing Methods 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 238000012163 sequencing technique Methods 0.000 description 1
- 210000002966 serum Anatomy 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 230000007306 turnover Effects 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
- 239000003643 water by type Substances 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
- G01N21/27—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands using photo-electric detection ; circuits for computing concentration
Abstract
The invention discloses a bone alkaline phosphatase analyzer. The bone alkaline phosphatase analyzer comprises a bottom plate and a detection chamber which is arranged at the top end of the bottom plate. A test head is arranged at the position of the top wall of an inspection port of the detection chamber; the bottom plate extends out of the detection chamber; a detection card tray mechanism which is driven by a power source to get in/out of the detection chamber back and forth; a first light transmitting hole, a second light transmitting hole and a third light transmitting hole are formed in the test head; the detection card tray mechanism consists of a rectangular tray body for placing a concave cavity of the detection card and trolley wheels arranged at the bottom of the rectangular tray body; the power source is a stepping motor which is engaged with racks arranged on the side walls of the rectangular tray body. The bone alkaline phosphatase analyzer provided by the invention realizes automatic reading of detection and analysis result of bone alkaline phosphatase, thereby greatly improving working efficiency and accuracy of the bone alkaline phosphatase.
Description
Technical field
The present invention relates to medical apparatus and instruments detection and analysis device is and in particular to a kind of bone source type alkaline phosphatase enzyme analyser.
Background technology
Bone source type alkaline phosphatase detecting reagent box (affine percolation) is a kind of in half-quantitative detection blood of human body
The activity of bone type alkali phosphatase, the bone calcification obstacle causing because of calcium malnutrition for examination and auxiliary diagnosis or other reasonses
A kind of detection kit of the metabolic osteopathy causing.The blood sample that its clinic needs is extremely micro, and only needs to finger tip
Blood is sampled, and is very suitable for the detection of children's bone source type alkali phosphatase, its manual manipulation method is in clinic: by test kit from
Take out in cold storage environment, place equilibrium at room temperature at least 30 minutes, tear packaging bag, take out Sptting plate, drip in Sptting plate well
Plus 2 cleaning mixture, wait to penetrate into, take peripheral blood 30 μ l (or micropipettor pipettes 17 μ l serum) with quantitative blood taking tube, be added to
In well, waiting to penetrate into it is generally the case that blood fully penetrates in 2-3 minute, if penetrating into bad, pressing blood plasma with handss
Separator, helps blood to penetrate into, after blood penetrates into, then in 2 cleaning mixture of well Deca, waits to penetrate into, take off from Sptting plate
It can be seen that circular reaction film below plasma separator, on reaction film, 2 cleaning mixture of Deca, wait to penetrate into plasma separator,
Driving a reaction slide plate, makes reaction film be located at reacting hole central authorities, in reacting hole central authorities 1 nitrite ion of Deca, puts 37 DEG C of waters bath with thermostatic control
Case reacts, 6-10 minute, takes out Sptting plate from constant water bath box, reaction slide plate is return in situ, in circular reaction film central authorities
1 terminate liquid of Deca, waits to penetrate into, terminating reaction；In 20 minutes, result is compareed with standard colorimetric plate, read mottle and colorimetric
Block measurement result the most close, this kind of determination method, the reading of result, judgement are more complicated, and work efficiency is relatively low, deposits simultaneously
In artificial empirical factor, sentence read result has certain error.Therefore, propose a kind of bone source type alkali phosphatase for the problems referred to above to divide
Analyzer.
Content of the invention
The purpose of the present invention is that to solve original determination method, judges more complicated, work efficiency is relatively low, with
When there is artificial empirical factor, sentence read result has a problem of certain error, and provides a kind of reading of achievable detection and analysis result
Take the bone source type alkaline phosphatase enzyme analyser of automatization.
The present invention is achieved through the following technical solutions above-mentioned purpose, a kind of bone source type alkaline phosphatase enzyme analyser, including
Base plate and the sensing chamber being arranged on described base plate top, are provided with measuring head and face at described sensing chamber's censorship mouth roof position
Colour sensor, described base plate extends outside described sensing chamber, and described base plate top is provided with and comes and goes turnover by power source drive
The detection Kato disc mechanism of described sensing chamber, described measuring head is provided with the first loophole, the second loophole and the 3rd printing opacity
Hole, described detection Kato disc mechanism by the rectangle disk body being provided with placement detection card cavity and is arranged on described rectangle disk body bottom
The roller in portion is constituted, and described power source is motor, and described motor passes through gear and is arranged on described rectangular disk side
Tooth bar on wall is meshed, and described rectangular disk intracoelomic cavity is provided with detection light source.
In a kind of preferred embodiment of the bone source type alkaline phosphatase enzyme analyser that the present invention provides, described second loophole
For straight hole structure vertically downward.
In a kind of preferred embodiment of the bone source type alkaline phosphatase enzyme analyser that the present invention provides, described first printing opacity
Hole, described third through-hole are the inclined hole structure tilting to described second loophole direction.
In a kind of preferred embodiment of the bone source type alkaline phosphatase enzyme analyser that the present invention provides, the bottom of described sensing chamber
End is closely connected with described base plate.
In a kind of preferred embodiment of the bone source type alkaline phosphatase enzyme analyser that the present invention provides, described detection Kato disk
Mechanism is connected to described motor by the engagement of described gear and described tooth bar.
The invention has the beneficial effects as follows: present configuration is reasonable in design, is examined detecting that card is sent into by described rectangle disk body
Survey interior and be located at below measuring head, timesharing is irradiated to detection card correspondence by described the first loophole often arranged to detection light source respectively
The the second loophole output through every row that diffuses produced by reagent area is accepted by color sensor；To lead to due to diffusing
Cross this specific light path of the second loophole to be received by color sensor, the optical signal that therefore color sensor receives is strong
Degree is reliable and stable to be converted into the signal of telecommunication through signal processing chip and control unit therein by color sensor optical signal
Plant and convert electrical signals into digital quantity, conversing corresponding reflectance finally by common digital quantity makes for subsequent data process
With；As test result is shown in the form of clinical meaning, can print and be transferred to computer it is achieved that the reading of analysis result
Take automatization, greatly improve work efficiency and the accuracy of detection and analysis result.
Brief description
For the technical scheme being illustrated more clearly that in the embodiment of the present invention, embodiment will be described below used in
Accompanying drawing be briefly described it should be apparent that, drawings in the following description are only some embodiments of the present invention, for ability
For the those of ordinary skill of domain, on the premise of not paying creative work, can also be obtained other attached according to these accompanying drawings
Figure, wherein:
The side structure schematic diagram of the bone source type alkaline phosphatase enzyme analyser that Fig. 1 provides for the present invention；
The overlooking the structure diagram of the bone source type alkaline phosphatase enzyme analyser that Fig. 2 provides for the present invention；
Fig. 3 is the a-a of the type alkaline phosphatase enzyme analyser of bone source shown in Fig. 1 to sectional view；
Fig. 4 is the i portion enlarged drawing of the type alkaline phosphatase enzyme analyser of bone source shown in Fig. 1.
In figure: 1, sensing chamber, 1a, censorship mouth, 1b, color sensor, 2, base plate, 3, measuring head, 4, to place detection card recessed
Chamber, 5, rectangle disk body, 5a, tooth bar, 5b, detection light source, 6, roller, 7, motor, 7a, gear, the 8, first loophole, 9, the
Two loopholes, the 10, the 3rd loophole.
Specific embodiment
Below in conjunction with the accompanying drawing in the embodiment of the present invention, the technical scheme in the embodiment of the present invention is carried out clear, complete
Site preparation describes it is clear that described embodiment is only a part of embodiment of the present invention, rather than whole embodiments.
Refer to shown in Fig. 1-4, a kind of bone source type alkaline phosphatase enzyme analyser, including base plate 2 and be arranged on described bottom
The sensing chamber 1 on plate 2 top, is provided with measuring head 3 and color sensor 1b at the censorship mouth 1a roof position of described sensing chamber 1,
Described base plate 2 extends outside described sensing chamber 1, and described base plate 2 top is provided with to be come and gone by power source drive and passes in and out described inspection
Survey the detection Kato disc mechanism b of room 1, described measuring head 3 is provided with the first loophole 8, the second loophole 9 and the 3rd loophole
10, described detection Kato disc mechanism b by the rectangle disk body 5 being provided with placement detection card cavity 4 and are arranged on described rectangular disk
The roller 6 of body 5 bottom is constituted, and described power source is motor 7, and described motor 7 by gear 7a and is arranged on described
Tooth bar 5a on rectangle disk body 5 side wall is meshed, and described rectangle disk body 5 inner chamber is provided with detection light source 5b.
Described second loophole 9 is straight hole structure vertically downward.
Described first loophole 8, described third through-hole 10 are the inclined hole structure tilting to described second loophole 9 direction,
Realize the sequencing of detection sensing.
The bottom of described sensing chamber 1 is closely connected with described base plate 2, improves the stability of structure.
Described detection Kato disc mechanism b is connected to described motor by the engagement of described gear 7a and described tooth bar 5a
7, realize the motion of described detection Kato disc mechanism b.
The present invention, when using, is located at below measuring head 3 by described rectangle disk body 5 by detecting card to send in sensing chamber 1,
Detection light source 5b respectively timesharing pass through described the first loophole 8 often arranged be irradiated to produced by the corresponding reagent area of detection card unrestrained instead
Penetrate the second loophole 9 through often arranging for the light and export and accepted by color sensor 1b；Due to diffuse will by the second loophole 9 this
One specific light path could be met 1b by color sensor and receive, and the light signal strength that therefore color sensor 1b receives is reliable and stable
The signal of telecommunication is converted into through signal optical signal by color sensor 1b, process chip and control unit one kind therein are telecommunications
Number it is converted into digital quantity, converses corresponding reflectance finally by common digital quantity and process for subsequent data and use, realize
Automatically read.
The foregoing is only embodiments of the invention, not thereby limit the present invention the scope of the claims, every using this
Equivalent structure or equivalent flow conversion that bright description is made, or directly or indirectly it is used in the technology neck of other correlations
Domain, is all included in the same manner within the scope of patent protection of the present invention.
Claims (5)
1. a kind of bone source type alkaline phosphatase enzyme analyser, including base plate and the sensing chamber that is arranged on described base plate top, it is special
Levy and be: be provided with measuring head and color sensor at the censorship mouth roof position of described sensing chamber, described base plate extends institute
State outside sensing chamber, described base plate top is provided with and is come and gone the detection Kato disk machine passing in and out described sensing chamber by power source drive
Structure, described measuring head is provided with the first loophole, the second loophole and the 3rd loophole, and described detection Kato disc mechanism is by setting
It is equipped with the rectangle disk body placing detection card cavity and the roller composition being arranged on described rectangle disk body bottom, described power source is
Motor, described motor is meshed with the tooth bar being arranged on described rectangular disk body sidewall by gear, described rectangle
Disk body inner chamber is provided with detection light source.
2. bone source according to claim 1 type alkaline phosphatase enzyme analyser it is characterised in that: described second loophole is vertical
Directly downward straight hole structure.
3. bone source according to claim 1 type alkaline phosphatase enzyme analyser it is characterised in that: described first loophole, institute
Stating third through-hole is the inclined hole structure tilting to described second loophole direction.
4. bone source according to claim 1 type alkaline phosphatase enzyme analyser it is characterised in that: the bottom of described sensing chamber with
Described base plate closely connects.
5. bone source according to claim 1 type alkaline phosphatase enzyme analyser it is characterised in that: described detection Kato disc mechanism
Connected to described motor by the engagement of described gear and described tooth bar.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610783533.0A CN106353261A (en) | 2016-08-31 | 2016-08-31 | Bone alkaline phosphatase analyzer |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610783533.0A CN106353261A (en) | 2016-08-31 | 2016-08-31 | Bone alkaline phosphatase analyzer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106353261A true CN106353261A (en) | 2017-01-25 |
Family
ID=57858110
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610783533.0A Pending CN106353261A (en) | 2016-08-31 | 2016-08-31 | Bone alkaline phosphatase analyzer |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN106353261A (en) |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN201540245U (en) * | 2009-12-10 | 2010-08-04 | 安图实验仪器(郑州)有限公司 | Joint inspection analyzer for department of gynaecology |
| CN203490223U (en) * | 2013-09-03 | 2014-03-19 | 天津朗赛生物科技有限公司 | Joint detection reagent card for ferritin and bone alkaline phosphatase in human blood |
| CN104678108A (en) * | 2015-03-04 | 2015-06-03 | 安徽惠邦生物工程股份有限公司 | Detecting card for bone alkaline phosphatase, hemoglobin and glutamic-pyruvic transaminase |
-
2016
- 2016-08-31 CN CN201610783533.0A patent/CN106353261A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN201540245U (en) * | 2009-12-10 | 2010-08-04 | 安图实验仪器(郑州)有限公司 | Joint inspection analyzer for department of gynaecology |
| CN203490223U (en) * | 2013-09-03 | 2014-03-19 | 天津朗赛生物科技有限公司 | Joint detection reagent card for ferritin and bone alkaline phosphatase in human blood |
| CN104678108A (en) * | 2015-03-04 | 2015-06-03 | 安徽惠邦生物工程股份有限公司 | Detecting card for bone alkaline phosphatase, hemoglobin and glutamic-pyruvic transaminase |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20170125 |