CN105021670B - Cycloheximide concentration analysis device and method based on surface acoustic wave series resonator biology tongue - Google Patents
Cycloheximide concentration analysis device and method based on surface acoustic wave series resonator biology tongue Download PDFInfo
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- CN105021670B CN105021670B CN201510067409.XA CN201510067409A CN105021670B CN 105021670 B CN105021670 B CN 105021670B CN 201510067409 A CN201510067409 A CN 201510067409A CN 105021670 B CN105021670 B CN 105021670B
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Abstract
The present invention relates to a kind of cycloheximide concentration analysis device and methods based on surface acoustic wave series resonator biology tongue.It solves the problems, such as existing of high cost using concentration analyzer.Device includes collecting work platform, collecting unit, converting unit and processing unit, collecting work platform includes pedestal, disk is provided on pedestal, multiple liquid storage cylinders are provided on disk, one side lower part of disk is provided with drip chamber, drip chamber bottom is provided with liquid droping head, it is provided with placing groove on the lower section pedestal of liquid droping head, collecting unit includes cell electrode plate and SAW resonator, cell electrode plate is located in placing groove, SAW resonator is connect with converting unit, and converting unit is connect with processing unit.It is an advantage of the invention that simple in structure, low manufacture cost, can automatically be detected a variety of solution concentrations, it is easy to operate, while reducing operating personnel's workload, save the time.Detection process is convenient and efficient, and precision is high.
Description
Technical field
The present invention relates to a kind of solution concentration detection technologies, are given birth to based on surface acoustic wave series resonator more particularly, to one kind
The cycloheximide concentration analysis device of object tongue, and the cycloheximide concentration analysis based on surface acoustic wave series resonator biology tongue
Method.
Background technology
It is frequently necessary to be detected the concentration of solution in the lab, when detecting solution concentration, usually using special
Concentration analyzer detection, but concentration analyzer is expensive, few then be also required to members up to ten thousand, and this considerably increases experimental costs.
Therefore, it is necessary to design it is a kind of simple in structure, it is swift to operate, low-cost concentration detection apparatus and the detection device
Detection method.
Invention content
The present invention is mainly to solve the problems, such as to use concentration analyzer of high cost in the prior art, provides a kind of structure letter
It is single, swift to operate, the cycloheximide concentration analysis device at low cost based on surface acoustic wave series resonator biology tongue.
The present invention also provides a kind of cycloheximide swift to operate based on surface acoustic wave series resonator biology tongue is dense
Spend analysis method.
The above-mentioned technical problem of the present invention is mainly to be addressed by following technical proposals：One kind being based on surface acoustic wave
The cycloheximide concentration analysis device of series resonator biology tongue, including collecting work platform, collecting unit, converting unit and processing
Unit, the collecting work platform includes pedestal, and rotary setting has disk on pedestal, and the center of circle is provided with multiple storages on disk
Sap cavity is provided with drip chamber in one side lower part of disk, and the drip chamber top is in contact with disk bottom, is set in fluid reservoir bottom
It is equipped with liquid outlet, the first solenoid valve is provided on liquid outlet, liquid outlet position is corresponded at the top of drip chamber and is provided with inlet,
It is provided with liquid droping head on the drip chamber bottom, wiper mechanism and drainage mechanism are provided in drip chamber, in the lower section of liquid droping head
Placing groove is provided on pedestal, the collecting unit includes the cell electrode plate and SAW resonator being connected, cell electricity
Pole plate is located in placing groove, and the SAW resonator is connect with converting unit, and converting unit is connect with processing unit.This
Invention collecting work platform automatically drips to various concentration solution on cell electrode plate respectively to be detected, and SAW resonator is adopted
Collect reaction information on cell electrode plate, converting unit is output in the form of frequency and is turned, converting unit acquires surface acoustic wave resonance
The frequency signal of device, and be converted into digital signal and be sent to processing unit, processing unit carries out resonance to digital signal and handles
To output signal-to-noise ratio value.Output signal-to-noise ratio value corresponding with N number of digital signal is obtained after being detected to various concentration solution,
Then solution concentration prediction model is obtained according to fitting a straight line.Can place a variety of strength solutions on disk, and according to setting every
A period of time rotates and a liquid storage luminal solution is added in drip chamber.Drip chamber drips to solution on cell electrode plate,
Surplus solution can be discharged after a kind of strength solution detects and drip chamber can be cleaned.The present invention can be automatically to difference
The concentration of strength solution is analyzed, simple to operate, waited for always without operating personnel side and manually replace detect it is molten
Liquid alleviates operating personnel's workload, has saved the time.Drip chamber of the present invention has cleaning function, when by a kind of the molten of concentration
After liquid discharge, wiper mechanism can be passed through water and be cleaned, and is passed through gas and dried up, and ensure that another strength solution enters
It will not be mixed with remaining liq before when drip chamber so that will not changing for solution concentration ensure that ultimate analysis data
Accuracy.
As a preferred embodiment, the wiper mechanism includes the water inlet and air inlet being connected to drip chamber inside, into
The mouth of a river is connect with water tank, and air inlet is connect with air pump, and entering water electromagnetic valve and air inlet are respectively arranged on water inlet and air inlet
Solenoid valve, the drainage mechanism include the discharge outlet being arranged in drip chamber bottom, and drain solenoid valve is provided in discharge outlet.Clearly
Washing machine structure cleans drip chamber.Discharge outlet is opened when cleaning, being passed through clear water by water inlet carries out water cleaning, after water cleaning
Air is passed through to being dried in drip chamber by air inlet, this makes the solution being added later mixed with Liquid Residue before
It closes so that solution concentration will not change, and ensure the accuracy of analysis result.
As a preferred embodiment, the liquid droping head is connected by micro pump with drip chamber.By micro pump by dropping liquid
Indoor solution is dropped according to set amount and time on cell electrode plate.
As a preferred embodiment, oxygenation rabbling mechanism is provided in drip chamber, oxygenation rabbling mechanism includes shaft, is turned
Pipeline is provided in axis, the shaft is connected with water inlet and air inlet, is connected with stirring pipe in shaft, in stirring pipe
Meta position, which installs, is equipped with shaft seat, and stirring pipe, according in shaft, constitutes T-type structure, stirring pipe is hollow seal by shaft seat
Pipe, stirring pipe are connected with shaft, several first stomatas are provided on end one end of stirring pipe, in the other end of stirring pipe
Head is provided with several second stomatas on the side opposite with the first stomata.It is indoor that air is passed into dropping liquid by oxygenation rabbling mechanism
In solution, increase the oxygen content of solution, while being passed through air can drive stirring pipe to be rotated, and can be stirred to solution,
So that solution is preferably mixed with air, increases oxygen content, after such solution drips on cell electrode plate, cell electrode plate can be made
On cell survival it is more preferable, survive longer life expectancy, ensure that the accuracy of detection data.
As a preferred embodiment, it is provided with the check valve for leading to stirring pipe on the pipeline of the shaft.Prevent water gentle
Body pours in down a chimney.
As a preferred embodiment, circle limit edge is provided on the lower edge of the disk side, in the dropping liquid ceiling
Limited block is provided in portion, limited block surface is arcwall face, and limited block surface is affixed closely with disk side, on limited block surface
It is correspondingly arranged on limiting slot, limit edge is embedded in limiting slot.Limit edge and limiting slot ensure that disk is in contact with drip chamber, circle
Disk does not deviate by position when rotating so that liquid outlet is aligned with inlet.
As a preferred embodiment, working electrode is provided on the cell electrode plate, to electrode and two reference electricity
The front end of pole, the working electrode is circle, which is made of foam copper, and is also coated with one on these foam coppers
Layer Gold plated Layer, cell are attached on working electrode front end, and the front end to electrode and reference electrode surrounds working electrode front end
Setting, and one layer of painting layer is coated on working electrode, the front end outer portion to electrode and reference electrode.Electrode is using bubble
Foam copper is equally distributed three-dimensional netted pore structure at, foam copper, the reticular structure with multi-layer stable and is completely embedded,
Reticular structure is unlikely to deform and collapses.This enables cell to enter foam copper inside configuration so that cell can preferably adhere to
On the electrode.Gold plated Layer is lower compared to foam Copper electrodissolution, is contacted with cell so that cell activity is more preferable, but also detection sensitivity
More preferably.
As a preferred embodiment, described erect on pedestal is provided with electric rotating machine, and the disk is mounted on electric rotating
In the shaft of machine, axle sleeve is provided with outside electric rotating machine shaft, the drip chamber is fixed on axle sleeve.
A kind of cycloheximide concentration analysis based on surface acoustic wave series resonator biology tongue, includes the following steps：
Step 1：Cycloheximide solution is placed in liquid storage cylinder opposite with drip chamber in disk, then by liquid storage cylinder
Interior solution injects drip chamber；Liquid storage cylinder is opposite with drip chamber, i.e. the liquid outlet of fluid reservoir and the inlet of drip chamber aligns.
Step 2：By micro pump on cell electrode plate dropping liquid, each dropping liquid amount is set as 0.05ml, when dropping liquid interval
Between be 3.4 seconds, dropping liquid number be 140 times, after dropping liquid, be discharged drip chamber in surplus solution and to drip chamber carry out cleaning blow
It is dry；Drain solenoid valve is opened, the indoor surplus solution of dropping liquid is discharged, drain solenoid valve is closed after discharge.Then water inlet is opened
Solenoid valve is passed through clear water, and opening drain solenoid valve again to being rinsed in drip chamber, after cleaning is drained.Close water inlet electromagnetism
Valve opens air inlet electromagnetic valve, is passed through gas to carrying out drying processing in drip chamber, finally closes drain solenoid valve.
Step 3：Signal on SAW resonator acquisition cell electrode plate exports in the frequency form, converting unit pair
Frequency signal carries out being converted to frequency curve, is then delivered on processing unit, processing unit is up-sampled in frequency curve
To input value S (t)；Input value S (t) is substituted into second-order linear system accidental resonance model, which is：
And second-order linearity coefficient accidental resonance model is made to resonate；Wherein x (t) is vibration particle displacement, and Ω is angular frequency, r
It is respectively the frequency of the attenuation coefficient and linear oscillator particle that set with ω, c is the signal adjustment coefficient of setting, and b is setting
Quadratic noise ξ2(t) coefficient, ξ (t) are three discrimination noises, and ξ (t) ∈ {-a, 0, a }, the dismutation of a ＞ 0, noise follow Poisson
Distribution, probability distribution ps(a)=ps(- a)=q, ps(0)=1-2q, wherein 0 ＜ q ＜ 0.5；Noise mean value is abided by with correlation
It follows<ξ(t)>=0,<ξ(t)ξ(t+τ)>=2qa2e-λτ；λ is correlation ratio, and the glacing flatness of three discrimination noise ξ (t) isObtain the output signal-to-noise ratio value of solution
Step 4：Output signal-to-noise ratio value is substituted into cycloheximide solution concentration prediction model：
Calculate the concentration of cycloheximide solution.
As a preferred embodiment, the cycloheximide solution concentration prediction model is calculated by following steps：
Step a：The cycloheximide solution of deployed a variety of concentration respectively, cycloheximide solution is respectively put into disk
In liquid storage cylinder, while inputting in processor the concentration value k of corresponding each cycloheximide solution1, k2..., kN；N is that detection is molten
The quantity of liquid.
Step b：Liquid storage luminal solution injection drip chamber opposite with drip chamber in disk is obtained according to step 2 and three
To the output signal-to-noise ratio value of solution；
Therefore, it is an advantage of the invention that：Simple in structure, low manufacture cost can automatically examine a variety of solution concentrations
It surveys, it is easy to operate, while reducing operating personnel's workload, save the time.Detection process is convenient and efficient, and precision is high.
Description of the drawings
Attached drawing 1 is a kind of structural frames diagram of the present invention；
Attached drawing 2 is a kind of structural schematic diagram of collecting work platform in the present invention；
Attached drawing 3 is a kind of structural schematic diagram of oxygenation rabbling mechanism in the present invention；
Attached drawing 4 is a kind of structural schematic diagram of cell electrode plate in the present invention.
1- collecting work platform 2- collecting unit 3- converting unit 4- processing unit 5- SAW resonator 6- cells
Electrode plate 7- pedestal 8- disk 9- liquid storage cylinder 10- drip chamber 11- placing groove 12- liquid outlet 13- liquid outlet electromagnetic valves 14-
Inlet 15- liquid droping head 16- air inlet 17- air inlet electromagnetic valve 18- water inlet 19- entering water electromagnetic valve 20- discharge outlet 21-
Drain solenoid valve 22- electric rotating machine 23- axle sleeve 24- micro pump 25- shaft 26- stirring pipe 27- shaft seats the first gas of 28-
The second stomatas of hole 29- 30- limits limit electrode 33- reference electrode 34- painting layers 35- along 31- working electrodes 32-
Slot 36- check valves
Specific implementation mode
Below with reference to the embodiments and with reference to the accompanying drawing the technical solutions of the present invention will be further described.
Embodiment：
A kind of cycloheximide concentration analysis device based on surface acoustic wave series resonator biology tongue of the present embodiment includes
Collecting work platform 1, collecting unit 2, converting unit 3 and processing unit 4.
As shown in Fig. 2, collecting work platform includes pedestal 7, it is vertically-mounted on pedestal to have electric rotating machine 22, electric rotating machine
Shaft on be provided with disk 8, be provided with axle sleeve 23 outside the shaft of electric rotating machine.It is evenly arranged with around the center of circle on disk multiple
Liquid storage cylinder 9 for placing solution is provided with drip chamber 10 in the lower part of disk side, and drip chamber is fixedly connected on axle sleeve,
The top of drip chamber is in contact with disk bottom.Circle limit is provided on the lower edge of disk side along 30, at the top of drip chamber
On be provided with limited block, limited block surface is arcwall face, and limited block surface is affixed closely with disk side, right on limited block surface
It should be provided with limiting slot 35, limit edge is embedded in limiting slot.
The bottom of liquid storage cylinder is provided with liquid outlet 12, liquid outlet electromagnetic valve 13 is provided on liquid outlet, in fluid reservoir
Top corresponds to liquid outlet position and is provided with inlet 14, and inlet diameter is more than liquid outlet diameter.It is set on the bottom of drip chamber
It is equipped with liquid droping head 15, micro pump 24 is provided on liquid droping head, by being connected inside micro pump and drip chamber.
It is provided with wiper mechanism and drainage mechanism in drip chamber, wiper mechanism includes water inlet 18 and air inlet 16, into
Gas port and water inlet converge into a pipeline then be connected inside drip chamber.Entering water electromagnetic valve 19 is provided on water inlet, into
The mouth of a river is connect by pipeline with water tank, and water pump is provided on pipeline.Be provided with air inlet electromagnetic valve 17 on air inlet, air inlet with
Air pump is connected.Drainage mechanism includes the discharge outlet 20 being arranged in drip chamber bottom, and drain solenoid valve is provided in discharge outlet
21。
Oxygenation rabbling mechanism is additionally provided in drip chamber, as shown in figure 3, oxygenation rabbling mechanism includes shaft 25, shaft
It is inside provided with pipeline, pipeline is connected with water inlet and air inlet in shaft, and stirring pipe 26 is connected in shaft, stirring pipe
Centre position is provided with shaft seat 27, and stirring pipe is mounted on by shaft seat in shaft, constitutes T-type structure, and stirring pipe is hollow
Seal pipe, stirring pipe are connected with shaft.Several first stomatas 28 are provided on end one end of stirring pipe, in stirring pipe
Several second stomatas 29 are provided on the side opposite with the first stomata of another end.It is provided on the pipeline of shaft and leads to stirring
The check valve 36 of pipe.
It is provided with placing groove 11 in liquid droping head lower base, places trench bottom and is provided with water outlet.
Collecting unit includes cell electrode plate 6 and SAW resonator 5, cell electrode plate connection sound surface packet resonator
On.When operation, cell electrode plate is placed in the placing groove of collecting work platform.As shown in Figure 1, SAW resonator and conversion
Unit is connected, and converting unit is connected with processing unit, and power supply is connected on SAW resonator.As shown in figure 4, cell
Working electrode 31 is provided on electrode plate, to electrode 32 and two reference electrodes 33.The front end of working electrode is circle, the circle
Part is made of foam copper, and one layer of Gold plated Layer is also coated on these foam coppers, and cell is attached on working electrode front end,
The front end of electrode and reference electrode is arranged around working electrode front end, and in working electrode, to electrode and reference electrode
One layer of painting layer 34 is coated on the outer portion of front end.
Based on the cycloheximide concentration analysis of surface acoustic wave series resonator biology tongue, include the following steps：
Step 1：Cycloheximide solution is placed in liquid storage cylinder opposite with drip chamber in disk, then by liquid storage cylinder
Interior solution injects drip chamber.
Step 2：By micro pump on cell electrode plate dropping liquid, each dropping liquid amount is set as 0.05ml, when dropping liquid interval
Between be 3.4 seconds, dropping liquid number be 140 times.After dropping liquid, drain solenoid valve is opened, the indoor surplus solution of dropping liquid is discharged,
Drain solenoid valve is closed after discharge.Then it opens entering water electromagnetic valve and is passed through clear water, to being rinsed in drip chamber, beaten again after cleaning
The water solenoid valve that begins to rehearse is drained.Entering water electromagnetic valve is closed, air inlet electromagnetic valve is opened, is passed through gas to being dried up in drip chamber
Processing, finally closes drain solenoid valve.
Step 3：Signal on SAW resonator acquisition cell electrode plate exports in the frequency form, converting unit pair
Frequency signal carries out being converted to frequency curve, is then delivered on processing unit, processing unit is up-sampled in frequency curve
To input value S (t)；Input value S (t) is substituted into second-order linear system accidental resonance model, which is：
And second-order linearity coefficient accidental resonance model is made to resonate；Wherein x (t) is vibration particle displacement, and Ω is angular frequency, r
It is respectively the frequency of the attenuation coefficient and linear oscillator particle that set with ω, c is the signal adjustment coefficient of setting, and b is setting
Quadratic noise ξ2(t) coefficient, ξ (t) are three discrimination noises, and ξ (t) ∈ {-a, 0, a }, the dismutation of a ＞ 0, noise follow Poisson
Distribution, probability distribution ps(a)=ps(- a)=q, ps(0)=1-2q, wherein 0 ＜ q ＜ 0.5；Noise mean value is abided by with correlation
It follows<ξ(t)>=0,<ξ(t)ξ(t+τ)>=2qa2e-λτ；λ is correlation ratio, and the glacing flatness of three discrimination noise ξ (t) isObtain the output signal-to-noise ratio value of solution
Step 4：Output signal-to-noise ratio value is substituted into cycloheximide solution concentration prediction model：
Calculate the concentration of cycloheximide solution.
Wherein cycloheximide solution concentration prediction model is calculated by following steps：
Step a：The cycloheximide solution of deployed a variety of concentration respectively, cycloheximide solution is respectively put into disk
In liquid storage cylinder, while inputting in processor the concentration value k of corresponding each cycloheximide solution1, k2..., kN；
Step b：Liquid storage luminal solution injection drip chamber opposite with drip chamber in disk is obtained according to step 2 and three
To the output signal-to-noise ratio value of solution；
Specific embodiment described herein is only an example for the spirit of the invention.Technology belonging to the present invention is led
The technical staff in domain can make various modifications or additions to the described embodiments or replace by a similar method
In generation, however, it does not deviate from the spirit of the invention or beyond the scope of the appended claims.
Although the terms such as collecting work platform, collecting unit, converting unit, processing unit are used more herein, simultaneously
It is not excluded for the possibility using other terms.The use of these items is only for more easily describe and explain the sheet of the present invention
Matter；Any one of the additional limitations is construed as all to disagree with spirit of that invention.
Claims (10)
1. a kind of cycloheximide concentration analysis device based on surface acoustic wave series resonator biology tongue, it is characterised in that：Including
Collecting work platform (1), collecting unit (2), converting unit (3) and processing unit (4), the collecting work platform (1) includes pedestal
(7), rotary setting has disk (8) on pedestal, is erect on the pedestal (7) and is provided with electric rotating machine (22), the disk
(8) it is mounted in the shaft of electric rotating machine (22), the center of circle is provided with multiple liquid storage cylinders (9) on disk (8), in disk (8)
One side lower part is provided with drip chamber (10), and drip chamber (10) top is touched with disk (8) bottom connection, at liquid storage cylinder (9) bottom
Portion is provided with liquid outlet (12), and liquid outlet electromagnetic valve (13) is provided on liquid outlet (12), corresponds at the top of drip chamber (10)
Liquid mouth (12) position is provided with inlet (14), is provided with liquid droping head (15) on drip chamber (10) bottom, is set in drip chamber
It is equipped with wiper mechanism and drainage mechanism, placing groove (11), the collecting unit are provided on the lower section pedestal of liquid droping head (15)
Including the cell electrode plate (6) being connected and SAW resonator (5), cell electrode plate is located in placing groove (11), institute
It states SAW resonator (5) to connect with converting unit (3), converting unit (3) is connect with processing unit (4).
2. the cycloheximide concentration analysis device according to claim 1 based on surface acoustic wave series resonator biology tongue,
It is characterized in that the wiper mechanism includes and the internal water inlet (18) being connected to of drip chamber (10) and air inlet (16), water inlet
(18) it is connect with water tank, air inlet (16) is connect with air pump, is respectively arranged with into water on water inlet (18) and air inlet (16)
Solenoid valve (19) and air inlet electromagnetic valve (17), the drainage mechanism include the discharge outlet (20) being arranged in drip chamber bottom, are being arranged
Drain solenoid valve (21) is provided on the mouth of a river (20).
3. the cycloheximide concentration analysis device according to claim 1 based on surface acoustic wave series resonator biology tongue,
It is characterized in that the liquid droping head (15) is connected by micro pump (24) with drip chamber (10).
4. the cycloheximide concentration analysis device according to claim 2 based on surface acoustic wave series resonator biology tongue,
It is characterized in that being provided with oxygenation rabbling mechanism in drip chamber (10), oxygenation rabbling mechanism includes shaft (25), and shaft (25) is interior
It is provided with pipeline, the shaft is connected with water inlet (18) and air inlet (16), and stirring pipe is connected in shaft (25)
(26), the centre position of stirring pipe (26) is provided with shaft seat (27), and stirring pipe (26) is mounted on shaft by shaft seat (27)
(25) on, T-type structure is constituted, stirring pipe (26) is hollow seal pipe, and stirring pipe (26) is connected with shaft (25), in stirring pipe
(26) several first stomatas (28) are provided on end one end, in another end of stirring pipe (26) and the first stomata (28) phase
Several second stomatas (29) are provided on the side of the back of the body.
5. the cycloheximide concentration analysis device according to claim 4 based on surface acoustic wave series resonator biology tongue,
It is characterized in that being provided with the check valve (36) for leading to stirring pipe (26) on the pipeline of the shaft (25).
6. the cycloheximide based on surface acoustic wave series resonator biology tongue according to claims 1 or 2 or 3 or 4 or 5 is dense
Analytical equipment is spent, it is characterized in that being provided with circle limit on the lower edge of the disk (8) side along (30), in the drip chamber
(10) limited block is provided on top, limited block surface is arcwall face, and limited block surface is affixed with disk side closely, in limited block
Limiting slot (35) is correspondingly arranged on surface, limit is embedded in along (30) in limiting slot (35).
7. the cycloheximide based on surface acoustic wave series resonator biology tongue according to claims 1 or 2 or 3 or 4 or 5 is dense
Analytical equipment is spent, it is characterized in that being provided with working electrode (31) on the cell electrode plate (6), joining to electrode (32) and two
Than electrode (33), the front end of the working electrode (31) is circle, which is made of foam copper, and in these foams
One layer of Gold plated Layer is also coated on copper, cell is attached on working electrode (31) front end, described to electrode (32) and reference electrode
(33) front end around working electrode (31) front end be arranged, and in working electrode (31), to electrode (32) and reference electrode (33)
Front end outer portion on be coated with one layer of painting layer (34).
8. the cycloheximide based on surface acoustic wave series resonator biology tongue according to claims 1 or 2 or 3 or 4 or 5 is dense
Analytical equipment is spent, it is characterized in that being provided with axle sleeve (23) outside electric rotating machine (22) shaft, the drip chamber (10) is fixed on axis
It covers on (23).
9. a kind of cycloheximide concentration analysis based on surface acoustic wave series resonator biology tongue, using claim 1-8
Device in any one, it is characterized in that including the following steps：
Step 1：Cycloheximide solution is placed in liquid storage cylinder opposite with drip chamber in disk, it then will be molten in liquid storage cylinder
Liquid injects drip chamber；
Step 2：By micro pump on cell electrode plate dropping liquid, set each dropping liquid amount as 0.05ml, dropping liquid interval time is
3.4 seconds, dropping liquid number was 140 times, after dropping liquid, surplus solution in drip chamber is discharged and carries out cleaning drying to drip chamber；
Step 3：Signal on SAW resonator acquisition cell electrode plate exports in the frequency form, and converting unit is to frequency
Signal carries out being converted to frequency curve, is then delivered on processing unit, and processing unit up-samples to obtain defeated in frequency curve
Enter value S (t)；Input value S (t) is substituted into second-order linear system accidental resonance model, which is：
And second-order linearity coefficient accidental resonance model is made to resonate；Wherein x (t) is vibration particle displacement, and Ω is angular frequency, r and ω
The frequency of the attenuation coefficient and linear oscillator particle that respectively set, c are the signal adjustment coefficients of setting, and b is the secondary of setting
Noise ξ2(t) coefficient, ξ (t) are three discrimination noises, and the dismutation of ξ (t) ∈ {-a, 0, a }, a ＞ 0, noise follow Poisson point
Cloth, probability distribution ps(a)=ps(- a)=q, ps(0)=1-2q, wherein 0<q<0.5；Noise mean value is followed with correlation<ξ
(t)>=0,<ξ(t)ξ(t+τ)>=2qa2e-λτ；λ is correlation ratio, and the glacing flatness of three discrimination noise ξ (t) is
To the output signal-to-noise ratio value of solution
Step 4：Output signal-to-noise ratio value is substituted into cycloheximide solution concentration prediction model：
Calculate the concentration of cycloheximide solution.
10. the cycloheximide concentration analysis according to claim 9 based on surface acoustic wave series resonator biology tongue,
It is characterized in that the cycloheximide solution concentration prediction model is calculated by following steps：
Step a：The cycloheximide solution of deployed a variety of concentration respectively, the liquid storage in disk is respectively put by cycloheximide solution
Intracavitary, while inputting in processor the concentration value k of corresponding each cycloheximide solution1,k2,...,kN；
Step b：Liquid storage luminal solution injection drip chamber opposite with drip chamber in disk is obtained molten according to step 2 and three
The output signal-to-noise ratio value of liquid；
Step c：Rotating circular disc keeps next liquid storage cylinder opposite with drip chamber, step b is repeated, in this way until all molten on disk
Liquid is all detected, and last processor obtains corresponding to the output signal-to-noise ratio value SNR of these solution1,SNR2,...,SNRN, then root
According to corresponding solution concentration k1,k2,...,kN, utilize (k1,SNR1),(k2,SNR2),...,(kN,SNRN) fitting be in line, root
Cycloheximide solution concentration prediction model is obtained according to the straight line of fitting：
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| CN204044164U (en) * | 2014-06-23 | 2014-12-24 | 珠海森龙生物科技有限公司 | Mini-clinical biochemical analyzer |
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| TW200928356A (en) * | 2007-12-26 | 2009-07-01 | Ind Tech Res Inst | Automatic leaching test system with constant pH control |
| CN103117728A (en) * | 2013-03-07 | 2013-05-22 | 浙江工商大学 | Acoustic surface wave resonator |
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