CN104125811B - 具有超声成像能力的切除探针 - Google Patents

具有超声成像能力的切除探针 Download PDF

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CN104125811B
CN104125811B CN201280070227.2A CN201280070227A CN104125811B CN 104125811 B CN104125811 B CN 104125811B CN 201280070227 A CN201280070227 A CN 201280070227A CN 104125811 B CN104125811 B CN 104125811B
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ultra sonic
sonic imaging
resection electrode
imaging sensor
probe
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CN104125811A (zh
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达雷尔·L·兰金
约瑟夫·V·科布利什
绍博尔奇·德拉第
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Boston Scientific Scimed Inc
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
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    • A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
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    • A61B18/1206—Generators therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/12—Diagnosis using ultrasonic, sonic or infrasonic waves in body cavities or body tracts, e.g. by using catheters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
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Abstract

公开了用于在身体内部超声地成像解剖结构并且执行切除疗法的设备与系统。结合的切除与超声成像探针包括具有构造为传送切除能量的切除电极的切除电极末端，以及构造为使围绕探针的组织成像的多个超声成像传感器。超声成像传感器经由末端插入件支撑在末端的内部，并且通过贯穿末端形成的声学开口传送超声波。末端插入件将末端内的内腔分成近端流体室与远端流体室。在切除手术期间，超声成像传感器可以承担产生可以显示在用户界面上的多个超声图像的任务。

Description

具有超声成像能力的切除探针
相关申请的交叉引用
本申请要求2011年12月28日提交的临时专利申请第61/580,705的优先权，其通过引用的方式整体包含于此。
技术领域
本公开大体上涉及用于在切除手术期间使身体内的组织成像的设备与系统。更具体地说，本公开涉及具有超声成像能力的切除探针。
背景技术
在切除疗法中，通常有必要确定在身体内的目标切除位置处的身体组织的多个特征。例如，在介入性心脏电生理(EP)手术中，对外科医生而言通常有必要确定在心脏中或在心脏附近的目标切除位置处的心脏组织的情况。在一些EP手术期间，外科医生可以通过主静脉或主动脉将标测导管传送到待治疗的心脏的内部区域中。然后外科医生可以利用标测导管通过将由导管承载的多个标测元件布置为与相邻心脏组织接触来确定心律紊乱源或异常源并且然后操作导管以产生心脏的内部区域的电生理学图。一旦产生心脏之图，外科医生就可以将切除导管推进到心脏中，并且将由导管末端承载的切除电极定位在目标心脏组织附近以切除组织并且形成伤口，由此治疗心律紊乱或异常。在一些技术中，切除导管自身可以包括多个标测电极，以允许相同的设备用于标测与切除。
已经开发出多种超声为基础的成像导管与探针以便在诸如介入性心脏病学、介入放射学和电生理学的应用中直接可视化身体组织。例如，对于介入性心脏电生理手术来说，已经开发了允许直接且实时地可视化心脏的解剖结构的超声成像设备。例如，在一些电生理手术中，可以利用超声导管来成像内心房隔膜，以引导心房隔膜的经中隔交叉，以定位与成像肺静脉，以及监控心脏的心房室的穿孔、心包积液的信号。
多种超声为基础的成像系统包括成像探针，所述成像探针与用于关于患者执行疗法的标测与切除导管分离。因此，位置跟踪系统有时用于跟踪每个设备在身体内的位置。在一些手术中，对于外科医生来说可能很难快速并且准确地确定待切除的组织的情况。此外，在不参照从诸如透视成像系统的单独成像系统获得的图像的情况下，通常很难领会与理解利用多种超声为基础的成像系统获得的图像。
发明内容
本公开大体上涉及用于在切除手术期间使身体内的解剖结构成像的设备与系统。
在实例1中，用于治疗与成像本体组织的切除探针，包括：切除电极末端，其包括构造为将切除能量传送到身体组织的切除电极；多个声学开口，它们贯穿切除电极末端布置；远侧末端插入件，其布置在切除电极末端的内腔内，远侧末端插入件包括多个流体通道；以及多个超声成像传感器，它们联接到远侧末端插入件，超声成像传感器构造为通过声学开口传输超声波。
在实例2中，根据实例1所述的探针，其中切除电极末端包括管状金属壳体。
在实例3中，根据实例1或2中任一个所述的探针，其中远侧末端插入件包括多个凹槽，每个凹槽都构造为容纳超声成像传感器。
在实例4中，根据实例1-3中任一个所述的探针，其中切除电极末端的内腔包括近端流体室与远端流体室，并且其中近端流体室与远端流体室通过远侧末端插入件分开并且经由流体通道流体地相互联接。
在实例5中，根据实例1-4中任一个所述的探针，其中远侧末端插入件包括具有近端部分与远端部分的大体圆柱状的插入件本体。
在实例6中，根据实例5所述的探针，其中流体通道沿着远端插入件本体的近端部分纵向地延伸。
在实例7中，根据实例1-5中任一个所述的探针，其中超声成像传感器周向地布置在远侧末端插入件周围。
在实例8中，根据实例1-7中任一个所述的探针，其中流体通道周向地布置在远侧末端插入件周围。
在实例9中，根据实例1-8中任一个所述的探针，其中流体通道与超声成像传感器周向地偏离。
在实例10中，根据实例1-9中任一个所述的探针，还包括联接到切除电极末端的细长探针本体。
在实例11中，根据实例1-10中任一个所述的探针，还包括将细长探针本体的远端部分联接到切除电极末端的近侧末端插入件。
在实例12中，根据实例1-11中任一个所述的探针，还包括贯穿切除电极末端布置的多个冲洗端口。
在实例13中，根据实例12所述的探针，其中冲洗端口定位于在声学开口远端和/或近端的切除电极末端周围。
在实例14中，根据实例1-13中任一个所述的探针，其中超声成像传感器包括构造为从切除电极末端的侧面传输超声波的多个横向面向超声成像传感器。
在实例15中，根据实例14的探针，其中横向面向超声成像传感器各自都联接到远侧末端插入件内的凹槽。
在实例16中，根据实例1-15中任一个所述的探针，其中超声成像传感器包括构造为在远离切除电极末端的远端的向前方向上传输超声波的至少一个面向远端超声成像传感器。
在实例17中，根据实例16的探针，其中远侧面向超声成像传感器联接到远侧末端插入件内的内孔。
在实例18中，用于治疗与成像本体组织的切除探针包括：细长探针本体，其具有近端部分与远端部分；切除电极末端，其联接到细长探针本体的远端部分，切除电极末端包括构造为将切除能量传送到身体组织的切除电极；多个声学开口，它们贯穿切除电极末端布置；远侧末端插入件，其布置在所述切除电极末端的内腔内，所述远侧末端插入件将所述内腔分成近端流体室与远端流体室；多个横向面向超声成像传感器，所述多个横向面向超声成像传感器各自都联接到远侧末端插入件内的相应凹槽，所述横向面向超声成像传感器各自都构造为从所述切除电极末端的侧面传输超声波；多个流体通道，它们布置在所述远侧末端插入件的外部范围周围并且与超声成像传感器周向地偏离；以及面向远端超声成像传感器，其联接到远端插入件，该面向远端超声成像传感器构造为沿着远离切除电极末端的远端的向前方向传输超声波。
在实例19中，切除与超声成像系统，其包括：探针，其构造为将切除能量传送到身体组织，所述探针包括切除电极末端，贯穿切除电极末端布置的多个声学开口，布置在切除电极末端的内腔内的远侧末端插入件，远侧末端插入件包括多个流体通道，以及联接到远侧末端插入件的多个超声成像传感器，超声成像传感器构造为通过声学开口传输超声波；切除疗法模块，其构造为产生电信号并且将电信号供给到切除电极末端；以及超声成像模块，其构造为处理从所述超声成像传感器接收的超声成像信号。
在实例20中，根据实例19的系统，其中超声成像模块包括：信号发生器，其构造为产生用于控制各超声成像传感器的控制信号；以及图像处理器，其构造为处理从各超声成像传感器接收的电信号并且产生多个超声图像。
尽管公开了多个实施方式，但对于本领域中的技术人员来说，通过下面示出并且描述本发明的示例性实施方式的详细描述，本发明的此外地其它实施方式将会变得显而易见。因此，附图与详细描述将被视为在性质上是描述性的而不是限定性的。
附图说明
图1是根据描述性实施方式的结合的切除与成像系统的示意图；
图2是更加详细地示出图1的结合的切除与超声成像探针的远端部分的立体图；
图3是切除电极末端的横截面视图；
图4是沿着图2的线4-4的切除电极末端的横截面视图；
图5是沿着图2的线5-5的射频电极的横截面视图；
图6是图3的近侧末端插入件的立体图；
图7是图3的远侧末端插入件的立体图；
图8是沿着图7中的线8-8的图7的远侧末端插入件的端视图；以及
图9是沿着图7的线9-9的远侧末端插入件的横截面视图。
尽管本发明接受多种修改与另选形式，但通过实例在附图中示出了并且在下面详细描述了特定实施方式。然而，本发明不使其限于所述的特定实施方式。相反地，本发明旨在覆盖落入如由所附权利要求限定的本发明的范围内的全部修改、等效物、以及另选物。
具体实施方式
图1是根据描述性实施方式的结合的切除与成像系统10的示意图。如图1中所示，系统10包括结合的切除与超声成像探针12、射频发生器14、流体储存器与泵16、以及超声成像模块18。探针12包括细长探针本体20，所述细长探针本体具有装配有把手组件24的近端部分22，以及包括切除电极末端28的可偏转远端部分26。探针本体20包括流体地联接到流体存储器与泵16的内冷却流体腔29，其通过探针本体20将诸如含盐的冷却流体供给到切除电极末端28中的多个冲洗端口30。探针本体20还可以包括用于支撑电导体、其它流体腔、热联接件、插入式管心针、以及其它部件的其它腔或者其它管状元件。在一些实施方式中，探针本体20包括柔性塑料管，所述柔性塑料管具有编织的金属网以增加本体20的旋转刚性。
射频发生器14构造为产生射频能量以便利用切除电极末端28执行切除程序。射频发生器14包括射频能量源32与用于控制通过末端28传送的射频能量的时间与等级的控制器34。在切除手术期间，射频发生器14构造为以受控的方式将切除能量传送到末端28，以便切除确定切除或者目标切除的任何部位。除了射频发生器14之外的或替代射频发生器14的其它类型的切除源也可以用于切除目标部位。其它类型的切除源的实例可以包括，但不限于，微波发生器、声学发生器、冷冻切除发生器、以及激光/光学发生器。
超声成像模块18构造为基于从定位在探针末端28内的几个超声成像传感器36接收的信号在身体内产生解剖结构的高解析度超声图像(例如，A、M或B模式图像)。在图1的实施方式中，超声成像单元18包括超声信号发生器40以及图像处理器42。超声信号发生器40构造为提供用于控制每个超声传感器36的电信号。将从超声成像传感器36接收回的成像信号继而供给到图像处理器42，所述图像处理器42处理信号并且产生可以显示在图形用户界面(GUI)44上的图像。在一些实施方式中，例如，显示在GUI44上的超声图像可以用于协助外科医生将探针12推进通过身体并且执行切除手术。例如，在心脏切除手术中，由超声信号产生的超声图像可以用于确认探针12在心脏或周围解剖内的的组织接触，以确定探针12在身体内的定位，从而确定在目标切除部位处的组织的深度，和/或可视化形成在组织中的伤口的进展。
可以控制与超声成像模块18内的超声成像传感器36以及回路相关联的多个特征以允许传感器36在切除手术以前、过程中和/或以后，准确地探测组织边界(例如，血液或者其它体液)、伤口形成与进展、以及组织的其它特征。可以利用探针12可视化的实例组织特征包括，但不限于，在组织内部存在流体汽化、存在现有伤疤、形成的伤口的尺寸与形状，以及邻近心脏组织(例如，肺、食管)的结构。超声成像传感器36可以可视化身体内的解剖结构的深度取决于传感器36的机械特征、包括信号发生器40的驱动频率的传感器回路的电特征、边界情况以及传感器36与周围解剖之间的衰减程度，以及其它因素。
在一些实施方式中，探针12进一步包括转向机构以允许操作者使探针12在身体内偏转与转向。在一个实施方式中，例如，可旋转地联接到把手24的诸如转向旋钮46的转向件可以用于使切除电极末端28相对于探针本体20的纵轴在一个或多个方向上偏转。转向旋钮46相对于把手24在第一方向上的转向运动致使探针本体20内的转向线相对于探针本体20向近侧移动，这继而使探身本体20的远端部分26弯曲成诸如圆弧状的特定形状。如示出的，转向旋钮46沿着相反方向的旋转移动，继而，致使探针本体20的远端部分26返回到其初始形状。并且在一些实施方式中，为协助偏转，探针本体20包括由比探针本体20的其它部分更低硬度材料制成的一个或多个区域。
尽管在医疗系统的背景下描述了在供诊断与治疗心脏的心内电生理手术中使用的系统10，在其它实施方式中系统10可以用于治疗、诊断、或者以其它方式可视化诸如前列腺、脑、胆囊、子宫、食道和/或身体内的其它区域的其它解剖结构。此外，在图1中的多个元件在性质上都是起作用的，并且不旨在以任何方式限定执行这些功能的结构。例如，几个功能块可以包含在单个设备中，或者一个或多个功能块可以包含在多个设备中。
图2是更加详细地示出图1的探针12的远端部分26的立体图。如可以在图2中进一步看到的，切除电极末端28包括构造为将切除能量传送到围绕末端28的本体组织的射频切除电极48。在图2的实施方式中，射频切除电极48包括从探针本体20的远端50延伸到末端28的远端52的管状金属壳体。通过切除电极末端28布置的多个暴露的开口54a、54b、54c形成允许超声波通过超声波成像传感器36a、36b、36c、36d传输通过末端28并且进入周围组织的声学开口。从组织接收回的反射超声波经过声学开口54a、54b、54c并且由以接收模式操作的超声波成像传感器36a、36b、36c、36d感测。在一些实施方式中，声学开口54a、54b、54c包括通过切除电极末端28的壁形成的暴露开口或穿孔。
除了用作切除电极以外，射频切除电极48还用作外壳，所述外壳包含超声波成像传感器36a、36b、36c、36d、将射频切除电极48联接到射频发生器14的电导体、将超声成像传感器36a、36b、36c、36d联接到超声成像模块18的电导体、转向机构的一根或多根转向线、以及其它部件。在一些实施方式中，射频切除电极48包括诸如铂铱的导电合金，所述导电合金除了用作用于提供切除疗法的电极之外，也用作荧光标记以利用荧光透视法确定切除电极末端28在身体内的位置。
在图2的实施方式中，探针12包括定位在切除电极末端28的远端52处或附近的面向远端超声成像传感器36a。在其它实施方式中，多个面向远端超声成像传感器36a定位在切除电极末端28的远端52处或附近。每个超声波传感器36a都构造为主要在远离切除电极末端28的远端52的向前或向远侧方向上传输超声波。在邻近面向远端超声成像传感器36a的位置处布置在末端28内的第二组超声成像传感器36b、36c、36d构造为主要在远离切除电极末端28的侧面的横向或面向侧面的方向上传输超声波。从超声成像传感器36a、36b、36c、36d接收回的反射波产生可以由超声成像模块18使用的信号以产生周围身体组织的图像。
在一些实施方式中，超声波成像传感器36a、36b、36c、36d各自都包括由诸如锆钛酸铅(PZT)的压电陶瓷材料或者诸如聚偏二氟乙烯(PVDF)的压电聚合物形成的压电式转换器。在一些实施方式中，切除电极末端28包括三个横向面向超声成像传感器36b、36c、36d，超声成像传感器36b、36c、36d各自都在末端28周围超声成像传感器都围绕以彼此隔开120°的间距周向地定向，以便用于定位在末端28的侧面附近的成像组织中使用。在其它实施方式中，利用更多或更少的横向面向超声成像传感器以使邻近探针末端28的侧面的组织成像。
在图2的实施方式中，切除电极末端28具有包括用于传送冷却流体以冷却末端28与周围组织的多个冲洗端口30的开口冲洗构造。在其它实施方式中，切除电极末端28具有闭合冲洗构造，其中冷却流体在不喷射到周围组织的情况下通过末端28再循环。在一些实施方式中，切除电极末端28包括六个冲洗端口30，每个冲洗端口30都在末端28周围以彼此隔开60°的间隔周向地布置并且在邻近面向远端超声传感器36a并且远离横向面向超声传感器36b、36c、36d位置的位置处。在其它实施方式中，使用更多或更少数量的流体冲洗端口30。在一些实施方式中，流体冲洗端口30的形状是圆形的，并且具有约0.005英寸到0.02英寸的范围的直径。然而，冲洗端口30的尺寸、数量和/或定位可以改变。在一些实施方式中，例如，切除电极末端28还包括周向地定位在最靠近横向面向超声传感器36b、36c、36d的末端28周围的多个流体冲洗端口30。在切除疗法期间，冷却流体用于控制温度并且减少在切除电极末端28上的凝块形成，由此防止与末端28接触的组织的阻抗升高并且增加从末端28传送到组织中的射频切除能量的传递。
图3是切除电极末端28的横截面视图。如可以在图3中进一步看到的，切除电极末端28包括：容纳超声成像传感器36a、36b、36c、36d的内腔56；用于将能量传输到传感器36a、36b、36c、36d并且接收从传感器36a、36b、36c、36d返回的信号的电导管58、60、62、63；以及用于将射频切除能量供给到射频电极48的电导管64。在一些实施方式中，电导管58、60、62、63、64包括绝缘管状件，所述绝缘管状件含有用于将射频发生器14电连接到射频电极48并且将超声成像模块18电连接到超声成像传感器36a、36b、36c、36d的引线。延伸通过探针12的流体导管66将冷却流体从流体存储器与泵16供给到切除电极末端28的内腔56，然后通过冲洗端口30将冷却流体传送到周围组织中。延伸通过探针12的热电偶导线68在远端终止在定位于内腔56内的热电偶70处，以便在切除手术过程中感测切除电极末端28的温度。
近侧末端插入件72用于将切除电极末端28联接到探针本体20的远端50。远侧末端插入件74构造为在切除电极末端28内支撑横向面向超声传感器36b、36c、36d，并且将内腔56分成近端流体室76与远端流体室78。沿着远侧末端插入件74的长度纵向延伸的多个流体通道80将近端流体室76流体地连接到远端流体室78。在切除过程中，当冷却流体进入近端流体室76时，在切除电极末端28内的远侧末端插入件74的存在产生背压，致使流体在被迫使通过通道80并且进入远端流体室78以前进行循环。
图4是沿着图3的线4-4的切除电极末端28的横截面视图。如可以结合图4进一步看出的，并且在一些实施方式中，远侧末端插入件74包括用于将冷却流体从近端流体室76供给到远端流体室78的三个流体通道80。如在图4中可以进一步看到的，并且在一些实施方式中，切除电极末端28包括在远侧末端插入件74的周边周围彼此以120°的角度α彼此等距间隔的三个横向面向超声成像传感器36b、36c、36d。尽管在图4的实施方式中示出了三个横向面向超声传感器36b、36c、36d，但是可以利用更多或更少数量的超声成像传感器。通过实例并且非限定地，可以将四个超声成像传感器以90°的等距角α布置在远侧末端插入件74的周边周围。在成像过程中，在远侧末端插入件74的周边周围隔开的多个超声成像传感器36b、36c、36d的使用，确保传感器36b、36c、36d中至少一个的视野靠近目标组织而与末端相对于目标组织的定向无关。一旦探针12与组织接触，此构造还允许外科医生在无需旋转探针12的情况下容易地可视化目标组织。
为了节省切除电极末端28内的空间，流体通道80每个都与超声成像传感器36b、36c、36d周向地偏离。在示出的实施方式中，其中使用三个横向面向超声成像传感器36b、36c、36d，每个流体通道80都在远侧末端插入件74的周边周围以120°的等距角β1周向地布置，并且与每个相邻超声成像传感器周向地偏离以约60°的角度β2。在其它实施方式中各个流体通道80之间的角度β1以及每个流体通道80与相邻超声成像传感器36b、36c、36d之间的角度β2可以基于所提供的流体通道和/或超声成像传感器的数量而改变。在一些实施方式中，流体通道80每个都具有相等的横截面积并且等距定位在远侧末端插入件74的中心周围。流体通道的数量与构造可以改变。例如，在一个实施方式中，流体通道与超声成像传感器的声学路径以所述方式周向地对准，例如，在共同未决申请号_______，标题为“具有用于超声组织成像的流体为基础的声学联接的切除探针”中，为了一切目的将其内容通过引用的方式整体包含于此。
图5是沿着图2的线5-5的射频电极48的横截面视图；如可以在图5中进一步看到的，射频电极48包括管状壳体82，所述管状壳体82包括在壳体82的周边周围彼此以60°的角度Φ等距隔开的六个冲洗端口30。在其它实施方式中冲洗端口30的数量、大小、以及各个冲洗端口30之间的角度Φ都可以改变。并且在一些实施方式中，为使冲洗流体与来自超声成像传感器36的超声波的传输的干扰最小化，冲洗端口30的中心与侧面面向声学开口54b、54c的中心周向地偏离。在切除电极末端28包括三个横向面向超声成像传感器36b、36c、36d与六个冲洗端口30的这些实施方式中，例如，冲洗端口30可以与各相邻侧面声学开口54b、54c周向地偏离约30°的角度。在其它实施方式中此周向偏离可以基于成像传感器36的数量与构造以及其它因素而改变。在一些实施方式中，冲洗端口30是圆形形状，并且具有在约0.005英寸到0.02英寸范围内的直径。
图6是图3的近侧末端插入件72的立体图。如可以在图6中进一步看到的，近侧末端插入件72包括具有近端部分86与远端部分88的中空金属插入件本体84。近端部分86构造为附接到探针本体20的远端50。继而，远端部分88相对于近端部分86具有扩大的外径，并且构造为附接到射频电极壳体82。在一些实施方式中，近侧末端插入件72经由摩擦配合、锡焊、焊接和/或粘性附接件联接到探针本体20的远端50以及联接到射频电极壳体82。在从近端部分86到远端部分88的过渡处的肩部90用作凸缘以对准与射频电极壳体82平齐的探针本体20的远端50。
贯穿近侧末端插入件72布置的第一腔92提供了用于将电信号与冷却流体供给到切除电极末端28的电及流体导管58、60、62、64、66的导管。贯穿近侧末端插入件72布置的第二腔94提供了用于使探针12偏转的转向机构的导管。
图7是图3的远侧末端插入件74的立体图。如图7中所示，远侧末端插入件74包括具有近端部分100与远端部分102的圆柱状金属本体98。在图7的实施方式中，近端部分100的外部范围104的尺寸设计为适配在邻近侧面声学开口54b、54c的位置的射频电极壳体82内，并且包括三个流体通道80。外部范围104还包括多个凹槽106，每个凹槽106都构造为将横向面向超声成像传感器36b、36c、36d中的相应一个容纳在其中。在一些实施方式中，凹槽106的尺寸与形状设计为容纳超声成像传感器36b、36c、36d，使得传感器36b、36c、36d与外部范围104基本上平齐地放置。定位在远侧末端插入件74的近端处的暴露开口108提供了将用于超声成像传感器36b、36c、36d的电导管供给到凹槽106中的通道。
远侧末端插入件74的远端部分102构造为在切除电极末端28内支撑面向远端超声成像传感器36a。远端部分102的外部范围110相对于近端部分100直径减小。此直径的减小形成经由流体通道80接收冷却流体的环状远端流体室78(参见图3)。
在插入件本体98的近端部分100内的穿孔112构造为接收用于感测切除电极末端28温度的热电偶的远端。如可以在图8-图9中进一步看到的，延伸通过插入件本体104的近端与远端部分108、110的第二中心孔114构造为容纳面向远端超声成像传感器36a以及将传感器36a连接到超声成像模块18的电导管63的一部分。在一些实施方式中，贯穿远端部分102布置的多个侧穿孔116用于允许面向远端超声成像传感器36a的对准与安装。
在不偏离本发明的范围的情况下可以对所述的示例性实施方式做出多种修改和增加。例如，尽管上述实施方式涉及特定的特征，本发明的范围还包括具有不同特征的组合的实施方式以及未包括所述全部特征的实施方式。因此，本发明的范围旨在包括落入权利要求及其全部等效物的范围内的全部此种另选、修改与变型。

Claims (18)

1.一种用于治疗与成像身体组织的切除探针，所述切除探针包括：
切除电极末端，其包括构造为将切除能量传送到身体组织的切除电极；
多个声学开口，它们贯穿切除电极末端布置；
远侧末端插入件，其布置在所述切除电极末端的内腔内，所述远侧末端插入件包括多个流体通道；以及
多个超声成像传感器，它们联接到所述远侧末端插入件，所述超声成像传感器构造为通过所述声学开口传输超声波，
所述多个超声成像传感器包括构造为从所述切除电极末端的侧面传输超声波的多个横向面向超声成像传感器，以及
所述多个超声成像传感器还包括构造为在远离所述切除电极末端的远端的向前方向上传输超声波的至少一个面向远端超声成像传感器。
2.根据权利要求1所述的探针，其中，所述切除电极末端包括管状金属壳体。
3.根据权利要求1所述的探针，其中，所述远侧末端插入件包括多个凹槽，每个所述凹槽都构造为容纳超声成像传感器。
4.根据权利要求1所述的探针，其中，所述切除电极末端的所述内腔包括近端流体室与远端流体室，并且其中，所述近端流体室与远端流体室通过所述远侧末端插入件分开并且经由所述流体通道流体地相互联接。
5.根据权利要求1所述的探针，其中，所述远侧末端插入件包括具有近端部分与远端部分的大体圆柱状的插入件本体。
6.根据权利要求5所述的探针，其中，所述流体通道沿着远端插入件本体的近端部分纵向地延伸。
7.根据权利要求1所述的探针，其中，所述超声成像传感器周向地布置在所述远侧末端插入件周围。
8.根据权利要求7所述的探针，其中，所述流体通道周向地布置在所述远侧末端插入件周围。
9.根据权利要求8所述的探针，其中，所述流体通道与所述超声成像传感器周向地偏离。
10.根据权利要求1所述的探针，还包括联接到所述切除电极末端的细长探针本体。
11.根据权利要求1所述的探针，还包括将所述细长探针本体的远端部分联接到所述切除电极末端的近侧末端插入件。
12.根据权利要求1所述的探针，还包括贯穿所述切除电极末端布置的多个冲洗端口。
13.根据权利要求12所述的探针，其中，所述冲洗端口定位于在所述声学开口远端和/或近端的所述切除电极末端周围。
14.根据权利要求1所述的探针，其中，所述横向面向的超声成像传感器各自都联接到所述远侧末端插入件内的凹槽。
15.根据权利要求1所述的探针，其中，所述面向远端超声成像传感器联接到所述远侧末端插入件内的内孔。
16.一种用于治疗与成像身体组织的切除探针，所述切除探针包括：
细长探针本体，其具有近端部分与远端部分；
切除电极末端，其联接到所述细长探针本体的所述远端部分，所述切除电极末端包括构造为将切除能量传送到身体组织的切除电极；
多个声学开口，它们贯穿切除电极末端布置；
远侧末端插入件，其布置在所述切除电极末端的内腔内，所述远侧末端插入件将所述内腔分成近端流体室与远端流体室；
多个横向面向超声成像传感器，每个所述多个横向面向超声成像传感器都联接到远侧末端插入件内的相应凹槽，所述横向面向超声成像传感器各自都构造为从所述切除电极末端的侧面通过所述声学开口传输超声波；
多个流体通道，它们布置在所述远侧末端插入件的外部范围周围并且与所述超声成像传感器周相地偏离；以及
面向远端超声成像传感器，其联接到所述远端插入件，所述面向远端超声成像传感器构造为在远离所述切除电极末端的远端的向前方向上通过所述声学开口传输超声波。
17.一种切除与超声成像系统，其包括：
探针，其构造为将切除能量传送到身体组织，所述探针包括：
切除电极末端；
多个声学开口，它们贯穿切除电极末端布置；
远侧末端插入件，其布置在所述切除电极末端的内腔内，所述远侧末端插入件包括多个流体通道；以及
多个超声成像传感器，它们联接到所述远侧末端插入件，所述超声成像传感器构造为通过所述声学开口传输超声波；
切除疗法模块，其构造为产生电信号并且将电信号供给到所述切除电极末端；以及
超声成像模块，其构造为处理从所述超声成像传感器接收的超声成像信号，所述多个超声成像传感器包括构造为从所述切除电极末端的侧面传输超声波的多个横向面向超声成像传感器，以及
所述多个超声成像传感器还包括构造为在远离所述切除电极末端的远端的向前方向上传输超声波的至少一个面向远端超声成像传感器。
18.根据权利要求17所述的系统，其中，所述超声成像模块包括：
信号发生器，其构造为产生用于控制每个超声成像传感器的控制信号；以及
图像处理器，其构造为处理从每个超声成像传感器接收的电信号并且产生多个超声图像。
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Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090093810A1 (en) * 2007-10-09 2009-04-09 Raj Subramaniam Electrophysiology Electrodes and Apparatus Including the Same
US9023030B2 (en) 2007-10-09 2015-05-05 Boston Scientific Scimed, Inc. Cooled ablation catheter devices and methods of use
EP2395934B1 (en) 2009-02-11 2019-04-17 Boston Scientific Scimed, Inc. Insulated ablation catheter devices
EP3391845B1 (en) 2009-06-30 2020-02-12 Boston Scientific Scimed, Inc. Map and ablate open irrigated hybrid catheter
US9089340B2 (en) 2010-12-30 2015-07-28 Boston Scientific Scimed, Inc. Ultrasound guided tissue ablation
EP2713888B1 (en) 2011-06-01 2019-09-04 Boston Scientific Scimed, Inc. Ablation probe with ultrasonic imaging capabilities
WO2013040297A1 (en) 2011-09-14 2013-03-21 Boston Scientific Scimed, Inc. Ablation device with ionically conductive balloon
CN103987336A (zh) 2011-09-14 2014-08-13 波士顿科学西美德公司 具有多种消融模式的消融装置
EP2757933B1 (en) 2011-09-22 2019-02-06 The George Washington University Systems for visualizing ablated tissue
JP5926806B2 (ja) 2011-09-22 2016-05-25 ザ・ジョージ・ワシントン・ユニバーシティＴｈｅ Ｇｅｏｒｇｅ Ｗａｓｈｉｎｇｔｏｎｕｎｉｖｅｒｓｉｔｙ アブレーションされた組織を視覚化するシステムと方法
US8876817B2 (en) 2012-01-10 2014-11-04 Boston Scientific Scimed Inc. Electrophysiology system and methods
US8945015B2 (en) 2012-01-31 2015-02-03 Koninklijke Philips N.V. Ablation probe with fluid-based acoustic coupling for ultrasonic tissue imaging and treatment
US20150251024A1 (en) * 2012-10-23 2015-09-10 Koninklijke Philips N.V. Spatial configuration determination apparatus
BR112015010140A2 (pt) * 2012-11-08 2017-07-11 Koninklijke Philips Nv dispositivo de intervenção e método para montar um dispositivo de intervenção
US10716536B2 (en) 2013-07-17 2020-07-21 Tissue Differentiation Intelligence, Llc Identifying anatomical structures
US10154826B2 (en) 2013-07-17 2018-12-18 Tissue Differentiation Intelligence, Llc Device and method for identifying anatomical structures
CN104605926A (zh) * 2013-11-05 2015-05-13 深圳迈瑞生物医疗电子股份有限公司 一种超声介入消融系统及其工作方法
EP3071095A4 (en) 2013-11-20 2017-07-26 The George Washington University Systems and methods for hyperspectral analysis of cardiac tissue
JP6397578B2 (ja) * 2014-09-17 2018-09-26 アバス サージカル，エル・エル・シー 解剖学的構造の識別
EP3206612B1 (en) 2014-10-13 2022-06-29 Boston Scientific Scimed Inc. Tissue diagnosis and treatment using mini-electrodes
JP6412275B2 (ja) * 2014-10-17 2018-10-24 ユニバーシティ オブ ワシントンＵｎｉｖｅｒｓｉｔｙ ｏｆ Ｗａｓｈｉｎｇｔｏｎ 広範集束超音波推進プローブ、システム、及び方法
US10603105B2 (en) 2014-10-24 2020-03-31 Boston Scientific Scimed Inc Medical devices with a flexible electrode assembly coupled to an ablation tip
AU2015343258B2 (en) 2014-11-03 2020-07-16 460Medical, Inc. Systems and methods for lesion assessment
WO2016073492A1 (en) 2014-11-03 2016-05-12 Luxcath, Llc. Systems and methods for assessment of contact quality
CA2967829A1 (en) 2014-11-19 2016-05-26 Advanced Cardiac Therapeutics, Inc. Systems and methods for high-resolution mapping of tissue
JP6673598B2 (ja) 2014-11-19 2020-03-25 エピックス セラピューティクス，インコーポレイテッド ペーシングを伴う組織の高分解能マッピング
AU2015349961A1 (en) 2014-11-19 2017-06-29 Epix Therapeutics, Inc. Ablation devices, systems and methods of using a high-resolution electrode assembly
EP3232969A1 (en) 2014-12-18 2017-10-25 Boston Scientific Scimed Inc. Real-time morphology analysis for lesion assessment
US9636164B2 (en) 2015-03-25 2017-05-02 Advanced Cardiac Therapeutics, Inc. Contact sensing systems and methods
US10779904B2 (en) 2015-07-19 2020-09-22 460Medical, Inc. Systems and methods for lesion formation and assessment
AU2016319002B2 (en) * 2015-09-09 2021-05-13 Boston Scientific Medical Device Limited Epicardial access system & methods
US11160607B2 (en) * 2015-11-20 2021-11-02 Biosense Webster (Israel) Ltd. Hyper-apertured ablation electrode
CA3017269A1 (en) 2016-03-15 2017-09-21 Epix Therapeutics, Inc. Improved devices, systems and methods for irrigated ablation
US11701086B1 (en) 2016-06-21 2023-07-18 Tissue Differentiation Intelligence, Llc Methods and systems for improved nerve detection
MX2019003483A (es) 2016-10-04 2019-09-02 Avent Inc Sondas rf frias.
EP3554405A1 (en) 2016-12-19 2019-10-23 Boston Scientific Scimed Inc. Open-irrigated ablation catheter with proximal insert cooling
EP3614946B1 (en) 2017-04-27 2024-03-20 EPiX Therapeutics, Inc. Determining nature of contact between catheter tip and tissue
US11648062B2 (en) 2017-11-09 2023-05-16 Acessa Health Inc. System for controlling ablation treatment and visualization
WO2020163449A1 (en) * 2019-02-05 2020-08-13 Canon U.S.A., Inc. Endoscope observation window cleaning
EP4241836A3 (en) * 2019-06-20 2023-11-29 Axon Therapies, Inc. Devices for endovascular ablation of a splanchnic nerve
JP2023550042A (ja) * 2020-11-12 2023-11-30 カーディオフォーカス，インコーポレーテッド 複数の内視鏡及び撮像チップ内視鏡を備えたアブレーションカテーテルならびに内視鏡画像の配向を変更するためのシステム
CN114533251B (zh) * 2022-02-21 2023-11-03 深圳市赛禾医疗技术有限公司 消融导管、导管消融系统、方法、装置以及存储介质

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999009879A1 (en) * 1997-08-27 1999-03-04 Pinotage, L.L.C. Controllable multi-directional surgical positioning device
WO2011024133A1 (en) * 2009-08-28 2011-03-03 Koninklijke Philips Electronics N.V. A catheter for open-loop irrigated ablation of tissue

Family Cites Families (255)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2123833A1 (de) 1971-05-13 1972-11-23 Siemens AG, 1000 Berlin u. 8000 München Kohärent optischer Vielkanalkorrelator
US4763660A (en) 1985-12-10 1988-08-16 Cherne Industries, Inc. Flexible and disposable electrode belt device
US5029588A (en) 1989-06-15 1991-07-09 Cardiovascular Imaging Systems, Inc. Laser catheter with imaging capability
US5240003A (en) 1989-10-16 1993-08-31 Du-Med B.V. Ultrasonic instrument with a micro motor having stator coils on a flexible circuit board
US5254088A (en) 1990-02-02 1993-10-19 Ep Technologies, Inc. Catheter steering mechanism
US5178150A (en) 1991-02-25 1993-01-12 Silverstein Fred E Miniature ultrasound imaging probe
CA2106378A1 (en) 1991-04-05 1992-10-06 Tom D. Bennett Subcutaneous multi-electrode sensing system
AU1899292A (en) 1991-05-24 1993-01-08 Ep Technologies Inc Combination monophasic action potential/ablation catheter and high-performance filter system
US5383874A (en) 1991-11-08 1995-01-24 Ep Technologies, Inc. Systems for identifying catheters and monitoring their use
US5697882A (en) 1992-01-07 1997-12-16 Arthrocare Corporation System and method for electrosurgical cutting and ablation
WO1994002077A2 (en) 1992-07-15 1994-02-03 Angelase, Inc. Ablation catheter system
US5385146A (en) 1993-01-08 1995-01-31 Goldreyer; Bruce N. Orthogonal sensing for use in clinical electrophysiology
US5579764A (en) 1993-01-08 1996-12-03 Goldreyer; Bruce N. Method and apparatus for spatially specific electrophysiological sensing in a catheter with an enlarged ablating electrode
DE69425249T2 (de) 1993-03-16 2001-03-22 Ep Technologies Träger-anordnung für mehrfach-elektroden
US6233491B1 (en) 1993-03-16 2001-05-15 Ep Technologies, Inc. Cardiac mapping and ablation systems
JP3898754B2 (ja) 1993-07-01 2007-03-28 ボストン サイエンティフィック リミテッド 像形成、電位検出型及び切除カテーテル
US5571088A (en) 1993-07-01 1996-11-05 Boston Scientific Corporation Ablation catheters
US5391199A (en) 1993-07-20 1995-02-21 Biosense, Inc. Apparatus and method for treating cardiac arrhythmias
US5385148A (en) 1993-07-30 1995-01-31 The Regents Of The University Of California Cardiac imaging and ablation catheter
US5582609A (en) 1993-10-14 1996-12-10 Ep Technologies, Inc. Systems and methods for forming large lesions in body tissue using curvilinear electrode elements
US5575810A (en) 1993-10-15 1996-11-19 Ep Technologies, Inc. Composite structures and methods for ablating tissue to form complex lesion patterns in the treatment of cardiac conditions and the like
US5462521A (en) 1993-12-21 1995-10-31 Angeion Corporation Fluid cooled and perfused tip for a catheter
US5485849A (en) 1994-01-31 1996-01-23 Ep Technologies, Inc. System and methods for matching electrical characteristics and propagation velocities in cardiac tissue
US5494042A (en) 1994-01-28 1996-02-27 Ep Technologies, Inc. Systems and methods for deriving electrical characteristics of cardiac tissue for output in iso-characteristic displays
US20080154257A1 (en) 2006-12-22 2008-06-26 Shiva Sharareh Real-time optoacoustic monitoring with electophysiologic catheters
US5876336A (en) 1994-10-11 1999-03-02 Ep Technologies, Inc. Systems and methods for guiding movable electrode elements within multiple-electrode structure
US6101409A (en) 1995-02-17 2000-08-08 Ep Technologies, Inc. Systems and methods for analyzing biopotential morphologies in body tissue
US6409722B1 (en) 1998-07-07 2002-06-25 Medtronic, Inc. Apparatus and method for creating, maintaining, and controlling a virtual electrode used for the ablation of tissue
US6575969B1 (en) 1995-05-04 2003-06-10 Sherwood Services Ag Cool-tip radiofrequency thermosurgery electrode system for tumor ablation
US5762067A (en) 1996-05-30 1998-06-09 Advanced Technology Laboratories, Inc. Ultrasonic endoscopic probe
US6210337B1 (en) 1995-06-07 2001-04-03 Atl Ultrasound Inc. Ultrasonic endoscopic probe
US5871483A (en) 1996-01-19 1999-02-16 Ep Technologies, Inc. Folding electrode structures
US6475213B1 (en) 1996-01-19 2002-11-05 Ep Technologies, Inc. Method of ablating body tissue
US5830213A (en) 1996-04-12 1998-11-03 Ep Technologies, Inc. Systems for heating and ablating tissue using multifunctional electrode structures
US5800482A (en) 1996-03-06 1998-09-01 Cardiac Pathways Corporation Apparatus and method for linear lesion ablation
AU728802B2 (en) 1996-05-17 2001-01-18 Biosense, Inc. Self-aligning catheter
US5904651A (en) 1996-10-28 1999-05-18 Ep Technologies, Inc. Systems and methods for visualizing tissue during diagnostic or therapeutic procedures
US5788636A (en) 1997-02-25 1998-08-04 Acuson Corporation Method and system for forming an ultrasound image of a tissue while simultaneously ablating the tissue
US5868735A (en) 1997-03-06 1999-02-09 Scimed Life Systems, Inc. Cryoplasty device and method
US6547788B1 (en) 1997-07-08 2003-04-15 Atrionx, Inc. Medical device with sensor cooperating with expandable member
US5902299A (en) 1997-07-29 1999-05-11 Jayaraman; Swaminathan Cryotherapy method for reducing tissue injury after balloon angioplasty or stent implantation
US6238389B1 (en) 1997-09-30 2001-05-29 Boston Scientific Corporation Deflectable interstitial ablation device
US6120476A (en) 1997-12-01 2000-09-19 Cordis Webster, Inc. Irrigated tip catheter
US5971979A (en) 1997-12-02 1999-10-26 Odyssey Technologies, Inc. Method for cryogenic inhibition of hyperplasia
US6917834B2 (en) 1997-12-03 2005-07-12 Boston Scientific Scimed, Inc. Devices and methods for creating lesions in endocardial and surrounding tissue to isolate focal arrhythmia substrates
EP0945104A1 (de) 1998-03-25 1999-09-29 Sulzer Osypka GmbH System und Verfahren zur Visualisierung von Aktivitäten eines Organs
US6059778A (en) 1998-05-05 2000-05-09 Cardiac Pacemakers, Inc. RF ablation apparatus and method using unipolar and bipolar techniques
US6171305B1 (en) 1998-05-05 2001-01-09 Cardiac Pacemakers, Inc. RF ablation apparatus and method having high output impedance drivers
US6050994A (en) 1998-05-05 2000-04-18 Cardiac Pacemakers, Inc. RF ablation apparatus and method using controllable duty cycle with alternate phasing
US6064905A (en) 1998-06-18 2000-05-16 Cordis Webster, Inc. Multi-element tip electrode mapping catheter
US6950689B1 (en) 1998-08-03 2005-09-27 Boston Scientific Scimed, Inc. Dynamically alterable three-dimensional graphical model of a body region
JP2002526188A (ja) 1998-09-24 2002-08-20 スーパー ディメンション リミテッド 体内への医療処置中にカテーテルの位置を判定するためのシステム及び方法
US20040006268A1 (en) 1998-09-24 2004-01-08 Super Dimension Ltd Was Filed In Parent Case System and method of recording and displaying in context of an image a location of at least one point-of-interest in a body during an intra-body medical procedure
US6116027A (en) 1998-09-29 2000-09-12 Air Products And Chemicals, Inc. Supplemental air supply for an air separation system
US6120445A (en) 1998-10-02 2000-09-19 Scimed Life Systems, Inc. Method and apparatus for adaptive cross-sectional area computation of IVUS objects using their statistical signatures
US7837624B1 (en) 1998-11-20 2010-11-23 Siemens Medical Solutions Usa, Inc. Medical diagnostic ultrasound imaging methods for extended field of view
US6673290B1 (en) 1998-11-12 2004-01-06 Scimed Life Systems, Inc. Electrode structure for heating and ablating tissue and method for making and assembling the same
US6290697B1 (en) 1998-12-01 2001-09-18 Irvine Biomedical, Inc. Self-guiding catheter system for tissue ablation
US6206831B1 (en) 1999-01-06 2001-03-27 Scimed Life Systems, Inc. Ultrasound-guided ablation catheter and methods of use
US7524289B2 (en) * 1999-01-25 2009-04-28 Lenker Jay A Resolution optical and ultrasound devices for imaging and treatment of body lumens
US6855123B2 (en) 2002-08-02 2005-02-15 Flow Cardia, Inc. Therapeutic ultrasound system
US6432102B2 (en) 1999-03-15 2002-08-13 Cryovascular Systems, Inc. Cryosurgical fluid supply
US6423002B1 (en) 1999-06-24 2002-07-23 Acuson Corporation Intra-operative diagnostic ultrasound multiple-array transducer probe and optional surgical tool
US6315732B1 (en) 1999-07-20 2001-11-13 Scimed Life Systems, Inc. Imaging catheter and methods of use for ultrasound-guided ablation
US6575966B2 (en) 1999-08-23 2003-06-10 Cryocath Technologies Inc. Endovascular cryotreatment catheter
US7232433B1 (en) 1999-09-22 2007-06-19 Siemens Medical Solutions Usa, Inc. Medical diagnostic ultrasound catheter with dielectric isolation
JP2003518404A (ja) 1999-12-28 2003-06-10 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ 移動部を有する対象物の超音波色分けイメージを表示する超音波イメージ処理方法及び装置
US6224557B1 (en) 2000-02-03 2001-05-01 Agilent Technologies, Inc. Ultrasonic method using adaptive clutter filter to remove tissue wall motion
US6508767B2 (en) 2000-02-16 2003-01-21 Koninklijke Philips Electronics N.V. Ultrasonic harmonic image segmentation
US6394956B1 (en) 2000-02-29 2002-05-28 Scimed Life Systems, Inc. RF ablation and ultrasound catheter for crossing chronic total occlusions
JP2003524506A (ja) 2000-03-01 2003-08-19 イナークール セラピーズ インコーポレイテッド 再狭窄を伴う血管形成術のための冷却療法及び装置
US6516667B1 (en) 2000-03-07 2003-02-11 Koninklijke Philips Electronics N.V. Ultrasonic harmonic signal acquisition
AU5468301A (en) 2000-03-15 2001-09-24 Boston Scientific Limited Ablation and imaging catheter
US6932811B2 (en) 2000-04-27 2005-08-23 Atricure, Inc. Transmural ablation device with integral EKG sensor
US6579278B1 (en) 2000-05-05 2003-06-17 Scimed Life Systems, Inc. Bi-directional steerable catheter with asymmetric fulcrum
US6537271B1 (en) 2000-07-06 2003-03-25 Cryogen, Inc. Balloon cryogenic catheter
US6635054B2 (en) 2000-07-13 2003-10-21 Transurgical, Inc. Thermal treatment methods and apparatus with focused energy application
US6656174B1 (en) 2000-07-20 2003-12-02 Scimed Life Systems, Inc. Devices and methods for creating lesions in blood vessels without obstructing blood flow
AU2001276954A1 (en) 2000-07-31 2002-02-13 Boston Scientific Limited Expandable atherectomy burr
US7037264B2 (en) 2000-08-17 2006-05-02 Koninklijke Philips Electronics N.V. Ultrasonic diagnostic imaging with steered image plane
JP2002078809A (ja) 2000-09-07 2002-03-19 Shutaro Satake 肺静脈電気的隔離用バルーンカテーテル
ES2241868T3 (es) 2000-09-08 2005-11-01 Atrionix, Inc. Dispositivo medico con sensor que coopera con un miembro dilatable.
US6544175B1 (en) 2000-09-15 2003-04-08 Koninklijke Philips Electronics N.V. Ultrasound apparatus and methods for display of a volume using interlaced data
US6640120B1 (en) 2000-10-05 2003-10-28 Scimed Life Systems, Inc. Probe assembly for mapping and ablating pulmonary vein tissue and method of using same
DE60121800T2 (de) 2000-12-11 2007-01-04 C.R. Bard, Inc. Vorrichtung zum mapping
US7047068B2 (en) 2000-12-11 2006-05-16 C.R. Bard, Inc. Microelectrode catheter for mapping and ablation
US6589182B1 (en) 2001-02-12 2003-07-08 Acuson Corporation Medical diagnostic ultrasound catheter with first and second tip portions
US6837884B2 (en) 2001-06-18 2005-01-04 Arthrocare Corporation Electrosurgical apparatus having compound return electrode
EP1404255A2 (en) 2001-06-19 2004-04-07 Eva Corporation Positioning assembly and method of use
US6582372B2 (en) 2001-06-22 2003-06-24 Koninklijke Philips Electronics N.V. Ultrasound system for the production of 3-D images
US6773402B2 (en) 2001-07-10 2004-08-10 Biosense, Inc. Location sensing with real-time ultrasound imaging
US6592525B2 (en) 2001-07-31 2003-07-15 Koninklijke Philips Electronics N.V. Micro-machined ultrasonic transducer (MUT) having improved sensitivity
US6632179B2 (en) 2001-07-31 2003-10-14 Koninklijke Philips Electronics N.V. Acoustic imaging system with non-focusing lens
US6585733B2 (en) 2001-09-28 2003-07-01 Ethicon, Inc. Surgical treatment for atrial fibrillation using radiofrequency technology
JP3607231B2 (ja) 2001-09-28 2005-01-05 有限会社日本エレクテル 高周波加温バルーンカテーテル
US6735465B2 (en) 2001-10-24 2004-05-11 Scimed Life Systems, Inc. Systems and processes for refining a registered map of a body cavity
US20030088240A1 (en) 2001-11-02 2003-05-08 Vahid Saadat Methods and apparatus for cryo-therapy
US6796980B2 (en) 2001-11-21 2004-09-28 Cardiac Pacemakers, Inc. System and method for validating and troubleshooting ablation system set-up
US7785324B2 (en) 2005-02-25 2010-08-31 Endoscopic Technologies, Inc. (Estech) Clamp based lesion formation apparatus and methods configured to protect non-target tissue
US7753908B2 (en) 2002-02-19 2010-07-13 Endoscopic Technologies, Inc. (Estech) Apparatus for securing an electrophysiology probe to a clamp
US6572549B1 (en) 2001-12-18 2003-06-03 Koninklijke Philips Electronics Nv High frame rate extended field of view ultrasound imaging system and method
AU2002367296A1 (en) 2001-12-28 2003-07-24 Ekos Corporation Multi-resonant ultrasonic catheter
US7648462B2 (en) 2002-01-16 2010-01-19 St. Jude Medical, Atrial Fibrillation Division, Inc. Safety systems and methods for ensuring safe use of intra-cardiac ultrasound catheters
US6932816B2 (en) 2002-02-19 2005-08-23 Boston Scientific Scimed, Inc. Apparatus for converting a clamp into an electrophysiology device
US20030158548A1 (en) 2002-02-19 2003-08-21 Phan Huy D. Surgical system including clamp and apparatus for securing an energy transmission device to the clamp and method of converting a clamp into an electrophysiology device
US6736814B2 (en) 2002-02-28 2004-05-18 Misonix, Incorporated Ultrasonic medical treatment device for bipolar RF cauterization and related method
US6705992B2 (en) 2002-02-28 2004-03-16 Koninklijke Philips Electronics N.V. Ultrasound imaging enhancement to clinical patient monitoring functions
US7166075B2 (en) 2002-03-08 2007-01-23 Wisconsin Alumni Research Foundation Elastographic imaging of in vivo soft tissue
JP3875581B2 (ja) 2002-03-18 2007-01-31 独立行政法人科学技術振興機構 超音波診断システム
US6743174B2 (en) 2002-04-01 2004-06-01 Koninklijke Philips Electronics N.V. Ultrasonic diagnostic imaging system with automatically controlled contrast and brightness
FR2839157A1 (fr) 2002-04-30 2003-10-31 Koninkl Philips Electronics Nv Systeme d'imagerie ultrasonore a haute resolution laterale
AUPS226402A0 (en) 2002-05-13 2002-06-13 Advanced Metal Coatings Pty Limited An ablation catheter
US6620103B1 (en) 2002-06-11 2003-09-16 Koninklijke Philips Electronics N.V. Ultrasonic diagnostic imaging system for low flow rate contrast agents
US6676606B2 (en) 2002-06-11 2004-01-13 Koninklijke Philips Electronics N.V. Ultrasonic diagnostic micro-vascular imaging
US6824517B2 (en) 2002-06-25 2004-11-30 Koninklijke Philips Electronics N.V. Ultrasound quantification in real-time using acoustic data in more than two dimensions
US6709396B2 (en) 2002-07-17 2004-03-23 Vermon Ultrasound array transducer for catheter use
TWI235073B (en) 2002-08-20 2005-07-01 Toray Industries Catheter for treating cardiac arrhythmias
US7220233B2 (en) 2003-04-08 2007-05-22 Flowcardia, Inc. Ultrasound catheter devices and methods
US7758508B1 (en) 2002-11-15 2010-07-20 Koninklijke Philips Electronics, N.V. Ultrasound-imaging systems and methods for a user-guided three-dimensional volume-scan sequence
US7105122B2 (en) 2002-10-08 2006-09-12 Ossur Hf Prosthesis socket direct casting device having multiple compression chambers
US6776758B2 (en) 2002-10-11 2004-08-17 Koninklijke Philips Electronics N.V. RFI-protected ultrasound probe
US7306593B2 (en) 2002-10-21 2007-12-11 Biosense, Inc. Prediction and assessment of ablation of cardiac tissue
US7001383B2 (en) 2002-10-21 2006-02-21 Biosense, Inc. Real-time monitoring and mapping of ablation lesion formation in the heart
AU2003278424A1 (en) 2002-11-06 2004-06-07 Koninklijke Philips Electronics N.V. Phased array acoustic system for 3d imaging of moving parts_____
US6692441B1 (en) 2002-11-12 2004-02-17 Koninklijke Philips Electronics N.V. System for identifying a volume of interest in a volume rendered ultrasound image
US7697972B2 (en) 2002-11-19 2010-04-13 Medtronic Navigation, Inc. Navigation system for cardiac therapies
US6796979B2 (en) 2002-12-11 2004-09-28 Cryocor, Inc. Coaxial catheter system for performing a single step cryoablation
US6922579B2 (en) 2002-12-12 2005-07-26 Scimed Life Systems, Inc. La placian electrode
JP4067976B2 (ja) 2003-01-24 2008-03-26 有限会社日本エレクテル 高周波加温バルーンカテーテル
US7534207B2 (en) 2003-02-07 2009-05-19 Alfred E. Mann Institute For Biomedical Engineering At The University Of Southern California Implantable device with sensors for differential monitoring of internal condition
WO2004072676A1 (en) 2003-02-13 2004-08-26 Koninklijke Philips Electronics N.V. Flow spectrograms synthesized from ultrasonic flow color doppler information
US7357800B2 (en) 2003-02-14 2008-04-15 Boston Scientific Scimed, Inc. Power supply and control apparatus and electrophysiology systems including the same
WO2004078066A2 (en) 2003-03-03 2004-09-16 Sinus Rhythm Technologies, Inc. Primary examiner
US20040186467A1 (en) 2003-03-21 2004-09-23 Swanson David K. Apparatus for maintaining contact between diagnostic and therapeutic elements and tissue and systems including the same
US7270634B2 (en) 2003-03-27 2007-09-18 Koninklijke Philips Electronics N.V. Guidance of invasive medical devices by high resolution three dimensional ultrasonic imaging
US7796789B2 (en) 2003-03-27 2010-09-14 Koninklijke Philips Electronics N.V. Guidance of invasive medical devices by three dimensional ultrasonic imaging
CN1764849B (zh) 2003-03-27 2010-05-26 皇家飞利浦电子股份有限公司 通过广角三维超声成像引导侵入式医疗设备
US7297116B2 (en) 2003-04-21 2007-11-20 Wisconsin Alumni Research Foundation Method and apparatus for imaging the cervix and uterine wall
US20040215177A1 (en) 2003-04-24 2004-10-28 Scimed Life Systems, Inc. Therapeutic apparatus having insulated region at the insertion area
US7131947B2 (en) 2003-05-08 2006-11-07 Koninklijke Philips Electronics N.V. Volumetric ultrasonic image segment acquisition with ECG display
JP4855926B2 (ja) 2003-06-03 2012-01-18 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ 旋回３次元超音波表示の振動対象との同期化
WO2004109328A1 (en) 2003-06-05 2004-12-16 Koninklijke Philips Electronics, N.V. Redundant wire bonds for increasing transducer reliability
US7347821B2 (en) 2003-06-26 2008-03-25 Koninklijke Philips Electronics N.V. Adaptive processing of contrast enhanced ultrasonic diagnostic images
US8048169B2 (en) 2003-07-28 2011-11-01 Baronova, Inc. Pyloric valve obstructing devices and methods
US20050059963A1 (en) 2003-09-12 2005-03-17 Scimed Life Systems, Inc. Systems and method for creating transmural lesions
US20050059862A1 (en) 2003-09-12 2005-03-17 Scimed Life Systems, Inc. Cannula with integrated imaging and optical capability
US7569052B2 (en) 2003-09-12 2009-08-04 Boston Scientific Scimed, Inc. Ablation catheter with tissue protecting assembly
US7438714B2 (en) 2003-09-12 2008-10-21 Boston Scientific Scimed, Inc. Vacuum-based catheter stabilizer
US7736362B2 (en) 2003-09-15 2010-06-15 Boston Scientific Scimed, Inc. Catheter balloons
ATE485004T1 (de) 2003-09-29 2010-11-15 Koninkl Philips Electronics Nv Ultraschallquantifizierung des herzvolumens
US20050090817A1 (en) 2003-10-22 2005-04-28 Scimed Life Systems, Inc. Bendable endoscopic bipolar device
CA2449080A1 (en) 2003-11-13 2005-05-13 Centre Hospitalier De L'universite De Montreal - Chum Apparatus and method for intravascular ultrasound image segmentation: a fast-marching method
US6958064B2 (en) 2003-11-14 2005-10-25 Boston Scientific Scimed, Inc. Systems and methods for performing simultaneous ablation
US7608072B2 (en) 2003-12-02 2009-10-27 Boston Scientific Scimed, Inc. Surgical methods and apparatus for maintaining contact between tissue and electrophysiology elements and confirming whether a therapeutic lesion has been formed
US8055357B2 (en) 2003-12-02 2011-11-08 Boston Scientific Scimed, Inc. Self-anchoring surgical methods and apparatus for stimulating tissue
US8002770B2 (en) 2003-12-02 2011-08-23 Endoscopic Technologies, Inc. (Estech) Clamp based methods and apparatus for forming lesions in tissue and confirming whether a therapeutic lesion has been formed
US8052676B2 (en) 2003-12-02 2011-11-08 Boston Scientific Scimed, Inc. Surgical methods and apparatus for stimulating tissue
US20050119653A1 (en) 2003-12-02 2005-06-02 Swanson David K. Surgical methods and apparatus for forming lesions in tissue and confirming whether a therapeutic lesion has been formed
US7371233B2 (en) 2004-02-19 2008-05-13 Boston Scientific Scimed, Inc. Cooled probes and apparatus for maintaining contact between cooled probes and tissue
AU2005231323B2 (en) 2004-03-26 2011-03-31 Ethicon Endo-Surgery, Inc Systems and methods for treating obesity
US20050228286A1 (en) 2004-04-07 2005-10-13 Messerly Jeffrey D Medical system having a rotatable ultrasound source and a piercing tip
US7507205B2 (en) 2004-04-07 2009-03-24 St. Jude Medical, Atrial Fibrillation Division, Inc. Steerable ultrasound catheter
WO2005096950A1 (en) 2004-04-08 2005-10-20 Koninklijke Philips Electronics N.V. Ultrasound probes with improved electrical isolation
EP1737348A1 (en) 2004-04-14 2007-01-03 Koninklijke Philips Electronics N.V. Ultrasound imaging probe featuring wide field of view
WO2005099606A1 (en) 2004-04-16 2005-10-27 Sydney West Area Health Service Biomedical return electrode having thermochromic layer
WO2005099579A1 (en) 2004-04-16 2005-10-27 Koninklijke Philips Electronics, N.V. Automated myocardial contrast echocardiography
US7582083B2 (en) 2004-05-10 2009-09-01 Boston Scientific Scimed, Inc. Probe based low temperature lesion formation apparatus, systems and methods
US7291142B2 (en) 2004-05-10 2007-11-06 Boston Scientific Scimed, Inc. Low temperature lesion formation apparatus, systems and methods
US7288088B2 (en) 2004-05-10 2007-10-30 Boston Scientific Scimed, Inc. Clamp based low temperature lesion formation apparatus, systems and methods
WO2005120363A1 (en) 2004-06-03 2005-12-22 Mayo Foundation For Medical Education And Research Obesity treatment and device
US7549988B2 (en) 2004-08-30 2009-06-23 Boston Scientific Scimed, Inc. Hybrid lesion formation apparatus, systems and methods
US7306561B2 (en) 2004-09-02 2007-12-11 Scimed Life Systems, Inc. Systems and methods for automatic time-gain compensation in an ultrasound imaging system
US20060100522A1 (en) 2004-11-08 2006-05-11 Scimed Life Systems, Inc. Piezocomposite transducers
US7776033B2 (en) 2005-01-08 2010-08-17 Boston Scientific Scimed, Inc. Wettable structures including conductive fibers and apparatus including the same
US7727231B2 (en) 2005-01-08 2010-06-01 Boston Scientific Scimed, Inc. Apparatus and methods for forming lesions in tissue and applying stimulation energy to tissue in which lesions are formed
US7862561B2 (en) 2005-01-08 2011-01-04 Boston Scientific Scimed, Inc. Clamp based lesion formation apparatus with variable spacing structures
US7585310B2 (en) 2005-01-14 2009-09-08 Boston Scientific Scimed, Inc. Minimally invasive clamp
US7918851B2 (en) 2005-02-14 2011-04-05 Biosense Webster, Inc. Irrigated tip catheter and method for manufacturing therefor
US7892228B2 (en) 2005-02-25 2011-02-22 Boston Scientific Scimed, Inc. Dual mode lesion formation apparatus, systems and methods
US7862562B2 (en) 2005-02-25 2011-01-04 Boston Scientific Scimed, Inc. Wrap based lesion formation apparatus and methods configured to protect non-target tissue
US7455669B2 (en) 2005-03-08 2008-11-25 Boston Scientific Scimed, Inc. Finger mountable lesion formation devices and methods
US20060253028A1 (en) 2005-04-20 2006-11-09 Scimed Life Systems, Inc. Multiple transducer configurations for medical ultrasound imaging
CA2605360C (en) 2005-04-21 2017-03-28 Asthmatx, Inc. Control methods and devices for energy delivery
US7517318B2 (en) 2005-04-26 2009-04-14 Biosense Webster, Inc. Registration of electro-anatomical map with pre-acquired image using ultrasound
US7658715B2 (en) 2005-05-04 2010-02-09 Fluid Medical Miniature actuator mechanism for intravascular imaging
JP5188389B2 (ja) 2005-05-05 2013-04-24 ボストン サイエンティフィック リミテッド 肺静脈口を画像として再構築する予成形した位置確認カテーテル及びシステム
US8016822B2 (en) 2005-05-28 2011-09-13 Boston Scientific Scimed, Inc. Fluid injecting devices and methods and apparatus for maintaining contact between fluid injecting devices and tissue
DE102005029762A1 (de) 2005-06-20 2006-12-21 Elringklinger Ag Dichtungsanordnung für einen Brennstoffzellenstapel und Verfahren zum Herstellen einer solchen Dichtungsanordnung
US8303510B2 (en) 2005-07-01 2012-11-06 Scimed Life Systems, Inc. Medical imaging device having a forward looking flow detector
US20070021744A1 (en) 2005-07-07 2007-01-25 Creighton Francis M Iv Apparatus and method for performing ablation with imaging feedback
US8945151B2 (en) 2005-07-13 2015-02-03 Atricure, Inc. Surgical clip applicator and apparatus including the same
US9955947B2 (en) 2005-07-15 2018-05-01 General Electric Company Device and method for shielding an ultrasound probe
US7859170B2 (en) 2005-08-08 2010-12-28 Koninklijke Philips Electronics N.V. Wide-bandwidth matrix transducer with polyethylene third matching layer
US20070073135A1 (en) 2005-09-13 2007-03-29 Warren Lee Integrated ultrasound imaging and ablation probe
US20070088345A1 (en) 2005-10-13 2007-04-19 Ust Inc. Applications of HIFU and chemotherapy
US7766833B2 (en) 2005-11-23 2010-08-03 General Electric Company Ablation array having independently activated ablation elements
US20070167821A1 (en) 2005-11-30 2007-07-19 Warren Lee Rotatable transducer array for volumetric ultrasound
US9492226B2 (en) 2005-12-06 2016-11-15 St. Jude Medical, Atrial Fibrillation Division, Inc. Graphical user interface for real-time RF lesion depth display
JP4702026B2 (ja) 2005-12-09 2011-06-15 コニカミノルタビジネステクノロジーズ株式会社 画像形成装置、及び画像形成装置の制御方法
US20070173680A1 (en) 2005-12-29 2007-07-26 Boston Scientific Scimed, Inc Apparatus and method for performing therapeutic tissue ablation and brachytherapy
US8401650B2 (en) 2008-04-10 2013-03-19 Electrocore Llc Methods and apparatus for electrical treatment using balloon and electrode
US20080009733A1 (en) 2006-06-27 2008-01-10 Ep Medsystems, Inc. Method for Evaluating Regional Ventricular Function and Incoordinate Ventricular Contraction
US8409172B2 (en) 2006-08-03 2013-04-02 Hansen Medical, Inc. Systems and methods for performing minimally invasive procedures
JP2008052181A (ja) 2006-08-28 2008-03-06 Brother Ind Ltd 定着装置および画像形成装置
US8403858B2 (en) 2006-10-12 2013-03-26 Perceptive Navigation Llc Image guided catheters and methods of use
US8690870B2 (en) 2006-12-28 2014-04-08 St. Jude Medical, Atrial Fibrillation Division, Inc. Irrigated ablation catheter system with pulsatile flow to prevent thrombus
WO2008118992A1 (en) * 2007-03-26 2008-10-02 Boston Scientific Scimed, Inc. High resolution electrophysiology catheter
US8577447B2 (en) 2007-05-01 2013-11-05 St. Jude Medical, Atrial Fibrillation Division, Inc. Optic-based contact sensing assembly and system
US8641704B2 (en) 2007-05-11 2014-02-04 Medtronic Ablation Frontiers Llc Ablation therapy system and method for treating continuous atrial fibrillation
US8428690B2 (en) 2007-05-16 2013-04-23 General Electric Company Intracardiac echocardiography image reconstruction in combination with position tracking system
US8216221B2 (en) 2007-05-21 2012-07-10 Estech, Inc. Cardiac ablation systems and methods
US8702609B2 (en) 2007-07-27 2014-04-22 Meridian Cardiovascular Systems, Inc. Image-guided intravascular therapy catheters
WO2009032421A2 (en) 2007-07-27 2009-03-12 Meridian Cardiovascular Systems, Inc. Image guided intracardiac catheters
US20090062790A1 (en) 2007-08-31 2009-03-05 Voyage Medical, Inc. Direct visualization bipolar ablation systems
US9023030B2 (en) 2007-10-09 2015-05-05 Boston Scientific Scimed, Inc. Cooled ablation catheter devices and methods of use
US20090093810A1 (en) * 2007-10-09 2009-04-09 Raj Subramaniam Electrophysiology Electrodes and Apparatus Including the Same
US10492854B2 (en) 2007-12-05 2019-12-03 Biosense Webster, Inc. Catheter-based acoustic radiation force impulse system
US8579889B2 (en) 2008-01-11 2013-11-12 Boston Scientific Scimed Inc. Linear ablation devices and methods of use
US8480663B2 (en) 2008-05-15 2013-07-09 Boston Scientific Scimed, Inc. Apparatus and methods for cryogenically ablating tissue and adjusting cryogenic ablation regions
US8133222B2 (en) 2008-05-28 2012-03-13 Medwaves, Inc. Tissue ablation apparatus and method using ultrasonic imaging
EP2355735A1 (en) 2008-09-02 2011-08-17 Medtronic Ablation Frontiers LLC Irrigated ablation catheter system and methods
US20100168568A1 (en) * 2008-12-30 2010-07-01 St. Jude Medical, Atrial Fibrillation Division Inc. Combined Diagnostic and Therapeutic Device Using Aligned Energy Beams
US9833217B2 (en) * 2008-12-31 2017-12-05 St. Jude Medical, Atrial Fibrillation Division, Inc. Methods and apparatus for utilizing impeller-based rotationally-scanning catheters
WO2010082146A1 (en) * 2009-01-14 2010-07-22 Koninklijke Philips Electronics N.V. Monitoring apparatus for monitoring an ablation procedure
US20100249604A1 (en) 2009-03-31 2010-09-30 Boston Scientific Corporation Systems and methods for making and using a motor distally-positioned within a catheter of an intravascular ultrasound imaging system
US8298149B2 (en) 2009-03-31 2012-10-30 Boston Scientific Scimed, Inc. Systems and methods for making and using a motor distally-positioned within a catheter of an intravascular ultrasound imaging system
US8647281B2 (en) 2009-03-31 2014-02-11 Boston Scientific Scimed, Inc. Systems and methods for making and using an imaging core of an intravascular ultrasound imaging system
JP5786108B2 (ja) 2009-05-08 2015-09-30 セント・ジュード・メディカル・ルクセンブルク・ホールディング・エスエーアールエル カテーテルアブレーション治療において病変部サイズを制御するための方法および装置
EP3391845B1 (en) 2009-06-30 2020-02-12 Boston Scientific Scimed, Inc. Map and ablate open irrigated hybrid catheter
CN102548496B (zh) 2009-09-15 2015-04-29 皇家飞利浦电子股份有限公司 具有力探测的医学超声设备
US20110071400A1 (en) 2009-09-23 2011-03-24 Boston Scientific Scimed, Inc. Systems and methods for making and using intravascular ultrasound imaging systems with sealed imaging cores
US20110071401A1 (en) 2009-09-24 2011-03-24 Boston Scientific Scimed, Inc. Systems and methods for making and using a stepper motor for an intravascular ultrasound imaging system
US20130023897A1 (en) 2009-10-06 2013-01-24 Michael P Wallace Devices and Methods for Endovascular Therapies
DE102009053470A1 (de) 2009-11-16 2011-05-26 Siemens Aktiengesellschaft Thermische Ablationsvorrichtung, Katheter sowie Verfahren zur Durchführung einer thermischen Ablation
US10688278B2 (en) * 2009-11-30 2020-06-23 Biosense Webster (Israel), Ltd. Catheter with pressure measuring tip
US9907534B2 (en) 2009-12-15 2018-03-06 St. Jude Medical, Atrial Fibrillation Division, Inc. Self-aiming directable acoustic transducer assembly for invasive medical device applications
US9694213B2 (en) * 2009-12-31 2017-07-04 St. Jude Medical, Atrial Fibrillation Division, Inc. Acoustic coupling for assessment and ablation procedures
JP2013517039A (ja) 2010-01-19 2013-05-16 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ 撮像装置
BR112012019262A2 (pt) 2010-02-05 2021-03-09 Koninklijke Philips Electronics N.V. Sistema para ablação combinada e imagem de ultrassom do tecido associado , metodo para avaliar um risco de um iminente dano do tecido devido a uma liberação rápida de uma energia da bolha, uso de um sistema para ablação combinada e imagem de ultrassom do tecido associado e produto de programa de computador sendo adaptado para um sistema de computador
WO2011101778A1 (en) 2010-02-19 2011-08-25 Koninklijke Philips Electronics N.V. Ablation catheter and a method of performing ablation
JP5841140B2 (ja) 2010-06-30 2016-01-13 コーニンクレッカ フィリップス エヌ ヴェＫｏｎｉｎｋｌｉｊｋｅ Ｐｈｉｌｉｐｓ Ｎ．Ｖ． エネルギーを対象物に付与するためのエネルギー付与装置
WO2012051305A2 (en) 2010-10-13 2012-04-19 Mau Imaging, Inc. Multiple aperture probe internal apparatus and cable assemblies
BR112013008821A2 (pt) 2010-10-14 2016-06-28 Koninkl Philips Electronics Nv aparelho de determinação de propriedades para determinar propriedades de objetos, método de determinação de propriedades para determinar propriedades de objetos e programa de computador de determinação de propriedades para determinar propriedade de objeto
CN103221148B (zh) 2010-11-18 2016-04-13 皇家飞利浦电子股份有限公司 具有嵌在挠性箔片内的超声波换能器的医疗设备
US9089340B2 (en) 2010-12-30 2015-07-28 Boston Scientific Scimed, Inc. Ultrasound guided tissue ablation
US20120172727A1 (en) 2010-12-30 2012-07-05 Boston Scientific Scimed, Inc. Imaging system
WO2012091903A1 (en) 2010-12-30 2012-07-05 Boston Scientific Scimed, Inc. Imaging assembly combining intravascular ultrasound and optical coherence tomography
EP2713888B1 (en) 2011-06-01 2019-09-04 Boston Scientific Scimed, Inc. Ablation probe with ultrasonic imaging capabilities
US9119636B2 (en) 2011-06-27 2015-09-01 Boston Scientific Scimed Inc. Dispersive belt for an ablation system
US9125668B2 (en) 2011-09-14 2015-09-08 Boston Scientific Scimed Inc. Ablation device with multiple ablation modes
WO2013040297A1 (en) 2011-09-14 2013-03-21 Boston Scientific Scimed, Inc. Ablation device with ionically conductive balloon
US8945015B2 (en) 2012-01-31 2015-02-03 Koninklijke Philips N.V. Ablation probe with fluid-based acoustic coupling for ultrasonic tissue imaging and treatment
EP2892433A1 (en) 2012-09-05 2015-07-15 Boston Scientific Scimed, Inc. Characterization of tissue by ultrasound echography
EP2897545A1 (en) 2012-09-20 2015-07-29 Boston Scientific Scimed, Inc. Nearfield ultrasound echography mapping
WO2014152575A2 (en) 2013-03-15 2014-09-25 Boston Scientific Scimed Inc. Ablation catheter with ultrasonic lesion monitoring capability

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999009879A1 (en) * 1997-08-27 1999-03-04 Pinotage, L.L.C. Controllable multi-directional surgical positioning device
WO2011024133A1 (en) * 2009-08-28 2011-03-03 Koninklijke Philips Electronics N.V. A catheter for open-loop irrigated ablation of tissue

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CN104125811A (zh) 2014-10-29
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